scholarly journals Features of blood`s microcirculation at physical loads

2020 ◽  
pp. 4-7
Author(s):  
Tetana Stanishevska ◽  
Оksana Gorna ◽  
Daria Horban ◽  
Olga Yusupova
Keyword(s):  
Physical Activity ◽  
Blood Flow ◽  
Physical Exertion ◽  
Doppler Flowmetry ◽  
Blood Microcirculation ◽  
Functional Reserves ◽  
State Pedagogical ◽  
Before And After ◽  
Human Cardiovascular System ◽  
Microcirculation Parameter

This research deals with the study of blood microcirculation peculiarities.Materials and methods. 72 students of Bogdan Khmelnytsky Melitopol State Pedagogical University, aged 18–19, were examined. The experimental research consisted of the study of blood microcirculation functional state by means of Laser Doppler flowmetry (LDF) method. It helped to evaluate the state of tissue blood-circulation and to detect individual-typological peculiarities of blood microcirculation under the influence of physical activity (before and after exercise).Results. Three types of blood microcirculation were identified by using LDF-metry. The normoemic type of blood microcirculation, characterized by the superposition of oscillatory rhythms and reflected the balance of the mechanisms of regulation of microcirculation. The hyperemic type, characterized by a «monotonous» LDF-gram with a high parameter of microcirculation, which reflects the relative predominance of metabolic mechanisms in the regulation of microcirculation. The hypoemic type, characterized by a «monotonous» LDF-gram with a low parameter of the microcirculation parameter, which reflects the decrease of vasomotor mechanisms in the regulation of microcirculation. According to the LDF-metric data, the examined students under intensive physical activity have a significant increase in microcirculatory status: by 6 % of the microcirculation parameter, by 28 % of the mean square deviation and by 45 % of the initial value of the coefficient of variation.Conclusions. This dynamics of microcirculation shows that under the influence of physical exertion, a person creates significant functional reserves for the redistribution of blood flow and for more perfect intraorgan capillary blood flow. It was found, that in the process of physical activity, morpho-functional rearrangements of the human cardiovascular system occur. This reaction is formed by several components of blood microcirculation: blood flow in the transport direction, regulating blood supply in accordance with the needs of tissues and the exchange component of the histochemical barrier

scholarly journals Features of the Dynamics of Infected and Septic Wounds Microcirculation in Children

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
O. V. Spahiu ◽  
A. P. Paholchuk
Keyword(s):  
Wound Healing ◽  
Blood Flow ◽  
Healing Process ◽  
Wound Healing Process ◽  
Doppler Flowmetry ◽  
Wound Area ◽  
Average Value ◽  
Process Dynamics ◽  
Area Monitoring ◽  
Microcirculation Parameter

Treatment of infected and septic wounds remains one of the most important problems of pediatric surgery. According to the authors, the wound process monitoring affects the treatment outcome not less than operative technique.The objective of the research was to examine the dynamics of microcirculation of the infected and septic wounds in children.Materials and methods. The analysis of the study of infected and septic wounds microcirculation in 178 children was performed. Blood flow laser analyzer (“LAKК-02” RPE “Lazma”, Russia) was used to study the blood flow in the wound area. Monitoring of wound healing process dynamics was conducted by studying the wound healing cytogram.Results. On the first day the average parameter of microcirculation was markedly increased in the area of wound edges in comparison with the contralateral area. The subsequent study of a blood flow during 5 days showed that average value of microcirculation parameter in the wound area decreased by more than 2 times in comparison with the figures on the first day. Microcirculation parameters of in the wound area further decreased.Conclusions. Dynamics of microcirculation changes in wound healing process significantly corresponds to cytogram of impression smears obtained from infected and septic wounds in children. Laser Doppler flowmetry is an effective method microcirculation control and minimally invasive diagnostic method of wound healing process.

scholarly journals Peripheral microcircuiation in patients over 60 years with atherosclerosis of lower limb arteries

2015 ◽  
Vol 17 (2) ◽  
pp. 22
Author(s):  
O. V. Kamenskaya ◽  
A. S. Klinkova ◽  
A. A. Karpenko ◽  
A. M. Karaskov ◽  
V. B. Starodubtsev ◽  
...  
Keyword(s):  
Lower Limb ◽  
High Volume ◽  
The Elderly ◽  
Early Postoperative Period ◽  
Lower Limbs ◽  
Orthostatic Test ◽  
Doppler Flowmetry ◽  
Functional Reserves ◽  
Before And After ◽  
Fontaine Classification

We investigated peripheral microcirculatory blood flow (MBF) by using laser Doppler flowmetry in 146 patients with IIB-IV stage chronic ischemia of lower limbs (CILL) according to the Pokrovsky-Fontaine classification. The objective was to study the state of peripheral MBF while carrying out functional tests in patients over 60 years with IIB-IV stage CILL before and after revascularization of lower limb arteries. When ageing, CILL patients demonstrate a decrease in the peripheral MBF baseline indicators and an increase in the quantity of defects of regulatory mechanisms and functional reserves of microcirculation, which manifest themselves as a severe paradoxical reaction of the microvasculature during an orthostatic test. In the early postoperative period the elderly patients tend to have reduced functional reserves and regulation mechanisms of MBF, with a high volume and degree of severity of MBF paradoxical reactions during an orthostatic test.

scholarly journals CHANGES IN THE ADAPTIVE CAPACITY OF DOGS OF DIFFERENT AGES TO WORKLOADS IN A MODERATE MONSOON CLIMATE

2020 ◽  
pp. 334-343
Author(s):  
A. S. Semenov ◽  
◽  
O. S. Poptsova ◽  
Keyword(s):  
Physical Activity ◽  
Physical Exertion ◽  
The Body ◽  
Monsoon Climate ◽  
Service Dogs ◽  
German Shepherd ◽  
Different Ages ◽  
Before And After ◽  
Different Seasons ◽  
Adaptive Ability

The article presents the results of changes in the adaptive ability of dogs of different ages before and after exposure to physical activity in different seasons of the year in the conditions of Sakhalin island (Yuzhno-Sakhalinsk). The main clinical and physiological parameters of the body of service dogs of the German shepherd breed were studied. The authors established a certain relationship between the degree of training and the response of the body of service dogs to physical activity in different seasons of the year. The most stressful periods for the life of service animals are summer and spring, and autumn and winter are consid-ered more comfortable. In General, the authors believe that service dogs are quite well adapted to use them in a moderate monsoon climate in the Yuzhno-Sakhalinsk region, regardless of age. Regular train-ing conducted with service dogs increases their resistance to physical exertion and endurance, so older dogs have adaptive abilities.

Effect of a Gel Formulation of Sucralfate on Gastric Microcirculation

1993 ◽  
Vol 21 (1) ◽  
pp. 47-50 ◽  
Author(s):  
M Guslandi ◽  
M Sorghi ◽  
A Foppa ◽  
PC Braga ◽  
A Tittobello
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Chronic Gastritis ◽  
Blood Perfusion ◽  
Mucosal Blood Flow ◽  
Gastric Blood Flow ◽  
Doppler Flowmetry ◽  
Before And After ◽  
Therapeutic Properties ◽  
Gastric Microcirculation

Dyspeptic patients ( n = 12) with endoscopic signs of chronic gastritis were treated orally for 28 days with a new gel formulation of sucralfate at a dose of 1 g twice daily. Before and after treatment, gastric blood flow was assessed during endoscopy by means of laser Doppler flowmetry. The sucralfate gel promoted a significant increase ( P < 0.001) in blood perfusion in all patients, restoring normal levels of gastric microcirculation. The results are consistent with observations in animals, suggesting that the mechanisms responsible for the gastroprotective and therapeutic properties of sucralfate include enhancement of mucosal blood flow.

scholarly journals STUDY OF HEMOMICROCIRCULATION IN UPPER- EXTREMITYSKIN IN HEALTHY MEN IN NORMAL CONDITIONS WITH ACCOUNT OF H

2020 ◽  
Vol 10 (4) ◽  
pp. 63-65
Author(s):  
Vadim Astashov ◽  
Valentin Kozlov ◽  
Victor Sidorov, ◽  
Mihail Uloga ◽  
Inna Borodina ◽  
...  
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Peripheral Blood ◽  
Upper Extremities ◽  
Laser Doppler ◽  
Peripheral Blood Flow ◽  
Doppler Flowmetry ◽  
Healthy Men ◽  
Young Males ◽  
Blood Microcirculation

In this study we used laser doppler flowmetry to investigate the parameters of peripheral blood flow in the upper extremities in young males both right- and left-handers. Based on the data obtained we found that in right-handers (dextrals) active mechanisms of regulation of blood microcirculation prevail on the leading hand, In left-handers (sinestrals) active and passive mechanisms of its regulation are involved in the regulation of blood flow on the leading hand (left) and on the opposite (right). However, the contribution of active mechanisms is lower than that of right-handers.

scholarly journals Peculiarities of local blood microcirculation in patients with the psoriasis

2018 ◽  
Vol 17 (3) ◽  
pp. 58-64
Author(s):  
E. V. Potapova ◽  
M. A. Filina ◽  
I. O. Kozlov ◽  
E. V. Zharkikh ◽  
V. V. Dremin ◽  
...  
Keyword(s):  
Blood Flow ◽  
Spectral Analysis ◽  
Laser Doppler Flowmetry ◽  
Psoriatic Lesion ◽  
Hemodynamic Parameters ◽  
Intact Skin ◽  
Doppler Flowmetry ◽  
Blood Microcirculation ◽  
Uninvolved Skin ◽  
Microcirculatory Disorders

The purpose of this work is to diagnose microcirculatory disorders in the tissues of psoriatic plaques in patients with psoriasis. Material and methods. Using the method of laser Doppler flowmetry (LDF), local hemodynamic parameters were studied in the place of psoriatic lesion of tissue and in uninvolved skin. Results. In the psoriatic plaque, there is an increase in average perfusion, myogenic and cardiac fluctuations, as well as nutritive blood flow as compared to the area of intact skin. Conclusions. The use of spectral analysis of the LDF signal has great potential for assessing the contribution of each link of the microvascular bed in the study the pathogenesis of psoriasis and evaluating the effectiveness of the therapy.

Temporal profile of vascular changes induced by systemic nitroglycerin in the meningeal and cortical districts

Cephalalgia ◽  
2010 ◽  
Vol 31 (2) ◽  
pp. 190-198 ◽  
Author(s):  
Rosaria Greco ◽  
Cristina Meazza ◽  
Antonina Stefania Mangione ◽  
Marta Allena ◽  
Monica Bolla ◽  
...  
Keyword(s):  
Blood Flow ◽  
Regional Blood Flow ◽  
Sprague Dawley ◽  
No Donor ◽  
Doppler Flowmetry ◽  
Additional Information ◽  
Sprague Dawley Rats ◽  
Before And After ◽  
Pre Treatment ◽  
Induced Changes

Background: Clinical studies indicated that nitric oxide (NO) donors cause regional changes in cerebral blood flow (CBF), similar to those reported in spontaneous migraine. Systemic nitroglycerin (NTG), a NO donor, is a well-accepted experimental model of migraine. In this study we have examined the effects of NTG on the meningeal and cortical blood flow in rats. Methods: Regional blood flow was monitored in male Sprague-Dawley rats using laser Doppler flowmetry before and after NTG/saline injection over 150 minutes. The effect of pre-treatment with Nω-nitro-L-arginine ester (L-NAME) or 7-nitroindazole (7-NI) on NTG-induced changes on blood flow was also investigated. Results: In the dura NTG caused a biphasic response represented by an initial decrease in blood flow followed by a significant increase. At variance, in the cortex NTG caused only an increase in blood flow. Pre-treatment with either L-NAME or 7-NI prevented NTG-induced increase in blood flow in both districts, while only L-NAME also prevented NTG-induced decrease in dural blood flow. Conclusion: The present findings provide additional information on the timing of effects of NTG on blood flow at both the meningeal and cortical levels. These effects seem to be related to vasoregulatory mechanisms and/or metabolic activity in response to the synthesis of endogenous NO.

scholarly journals L-NA-Sensitive rCBF Augmentation during Vibrissal Stimulation in Type III Nitric Oxide Synthase Mutant Mice

1996 ◽  
Vol 16 (4) ◽  
pp. 539-541 ◽  
Author(s):  
Cenk Ayata ◽  
Jianya Ma ◽  
Wei Meng ◽  
Paul Huang ◽  
Michael A. Moskowitz
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Regional Cerebral Blood ◽  
Doppler Flowmetry ◽  
Type Iii ◽  
Cranial Window ◽  
Window Technique ◽  
Before And After ◽  
Whisker Stimulation ◽  
Oxide Synthase

Regional cerebral blood flow (rCBF) was studied in type III nitric oxide (NO) synthase (endothelial, eNOS) mutant and wild type mice during mechanical whisker stimulation before and after nitro-L-arginine (L-NA) superfusion using the closed cranial window technique. rCBF increased equally in cortical barrel fields in both strains during stimulation, as measured by laser Doppler-flowmetry, and was inhibited by L-NA superfusion (1 m M) in both groups. Hence, coupling of blood flow and metabolism appears neuronal NOS- (nNOS) but not eNOS-dependent in cortical barrel fields of the mouse.

Spreading depression reversibly impairs autoregulation of cortical blood flow

1994 ◽  
Vol 266 (4) ◽  
pp. R1136-R1140 ◽  
Author(s):  
G. Florence ◽  
G. Bonvento ◽  
R. Charbonne ◽  
J. Seylaz
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Initial Phase ◽  
Cortical Spreading Depression ◽  
Time Course ◽  
Spreading Depression ◽  
Doppler Flowmetry ◽  
Cortical Blood Flow ◽  
Before And After

The experiment examines whether the mechanisms responsible for the autoregulation of cerebral blood flow (CBF) in response to hypotension were affected during the initial phase of cortical spreading depression (CSD). CSD was induced by a cortical pinprick in anesthetized rabbits, and CBF was measured by laser-Doppler flowmetry through a chronically implanted Plexiglas window. The reactivity to CO2 and papaverine was also studied before and after CSD. Fifteen minutes after CSD, autoregulatory vasodilation was reduced (P < 0.01). This impairment was reversible, since the autoregulatory response was restored 35 min after CSD. The time course of the reactivity to papaverine after CSD paralleled the autoregulatory response, with a significant correlation between the two reactivities (r = 0.47; P < 0.01). Conversely, the reactivity to CO2 was significantly reduced after CSD (P < 0.001) and remained affected for at least 95 min. We conclude that the mechanisms underlying autoregulation are transiently disturbed by CSD and that these mechanisms are not mediated by an accumulation of CO2 but seem instead to be related to an increase in adenosine 3',5'-cyclic monophosphate concentration.

scholarly journals ОСОБЛИВОСТІ МІКРОЦИРКУЛЯЦІЇ КРОВІ У СТУДЕНТІВ

2015 ◽  
Vol 5 (03) ◽  
pp. 122-129
Author(s):  
D. D. Horban ◽  
O. V. Yusupova ◽  
M. I. Sobichanska ◽  
V. G. Chorna
Keyword(s):  
Blood Flow ◽  
Functional State ◽  
Experimental Research ◽  
Nervous Activity ◽  
High Amplitude ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry ◽  
Blood Microcirculation ◽  
Higher Nervous Activity ◽  
Different Types

<p>The experimental research included the study of the functional state of blood microcirculation by means of laser Doppler flowmetry (LDF). Allowing to assess the condition of tissue blood flow and to detect the features of the microcirculation under different types of higher nervous activity. The obtained results showed that at most of students high-amplitude LDF was registered. Determining the characteristics of students` blood microcirculation with different types of higher nervous activity among healthy students 17-22 years showed that the prevailing strong and active types of temperament (choleric and sanguine) students hiperemichnym type of temperament. Percentage strong, but few mobile (phlegmatic) students was minimal and there was a greater number of students with hiperemichnym type of microcirculation, and the percentage weak sedentary (melancholic) type had a mean and often observed in students from normoemichnym type of blood microcirculation.</p> <p><em>Keywords: the blood microcirculation, LDF-metry,</em><em> </em><em>the</em><em> higher nervous activity, temperament.</em></p>

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