STRUCTURAL ELUCIDATION OF FIVE PHENOLIC COMPOUNDS FROM THE RHIZOMES OF CURCULIGO ANNAMITICA GAGNEP
Phytochemical research on the chloroform and ethyl acetate extracts of the rhizome of Curculigo annamitica Gagnep (Hypoxidaceae) collected in Binh Chau-Phuoc Buu Nature Reserve, Ba Ria - Vung Tau province, led to the isolation and structural elucidation of five phenolic compounds namely 2-hydroxy-3,4-dimethoxybenzoic acid (1), 2-hydroxy-6-methoxybenzoic acid (2), 4-hydroxybenzoic acid (3), p-coumaric acid (4) and 2-(ethoxymethyl)benzene-1,4-diol (5). Their chemical structures were confirmed by spectroscopic methods including HR-ESI-MS, 1D and 2D-NMR and compared with reported data. Compound 1 was known to be present for the first time from the family Hypoxidaceae.Keywords: Curculigo annamitica Gagnep (Hypoxidaceae), rhizome, phenolic compounds, 2-hydroxy-3,4-dimethoxybenzoic acid