Correlation of Implant Stability between two Non-Invasive Methods Using Submerged and non submerged healing protocols; A randomized clinical trail

Author(s):  
Marwa Abdel AAL ◽  
Mahmoud El Far ◽  
Nora Mohamed Sheta ◽  
Ahmed Fayyad ◽  
Eman El Desouky ◽  
...  

Various invasive and non-invasive methods have been used for measuring primary implant stability. Periotest damping device, and resonance frequency analysis (RFA) with the Osstell device have been classified as non-invasive methods.In this clinical randomized trial, a general correlation of primary implant stability was recorded using both the Osstell and Periotest device at the day of implant installation and 3 month after healing for the submerged and non submerged   loading protocols. The gender of included patients were investigated in the correlation of the two devices.Eighty completely edentulous patients were recruited, all patients were of age ranging from 50 to 69 years old. A single implant was installed in the midline of the completely edentulous mandible to improve retention of their lower denture. After implant installation, Implant Stability was recorded using the osstel and periotest device. Patients were then randomized into two groups using sealed envelopes; Submerged (S), and Non Submerged (NS). All ISQ and PTV were recorded at the day of implant installation, and 3 month after healing for both groups.When the ISQ was correlated to the (PTV), there was a moderate negative statistically significant correlation between the two readings, correlation coefficient= -0.466, p=0.000 . There tends to be a weak negative correlation between the two devices in the male group ,while there tends to be no correlation between the two devices in the female group After 3 month healing, there was no statistically significant correlation of the readings with in both groups ;NS and S ; Correlation coefficient =-0.014, -0.430, p=0.942, 0.052 respectively.   A strong negative statistically significant correlation between the two devices for the female group for both, NS and the S group. While there was no statistically significant correlation with in the male group for both groups.The present study concluded that there is a significant negative correlation between the two devices when recording primary implant stability, while this significance is lost after 3 month of loading when recording secondary implant stability. Gender would affect the implant stability recording, this would mainly due to the difference in bone density between the male and female group.

2016 ◽  
Vol 24 (4) ◽  
pp. 615-623 ◽  
Author(s):  
Nestor G. Rodriguez-Martinez ◽  
Luis Perez-Orribo ◽  
Samuel Kalb ◽  
Phillip M. Reyes ◽  
Anna G. U. S. Newcomb ◽  
...  

OBJECT The effects of obesity on lumbar biomechanics are not fully understood. The aims of this study were to analyze the biomechanical differences between cadaveric L4–5 lumbar spine segments from a large group of nonobese (body mass index [BMI] < 30 kg/m2) and obese (BMI ≥ 30 kg/m2) donors and to determine if there were any radiological differences between spines from nonobese and obese donors using MR imaging. METHODS A total of 168 intact L4–5 spinal segments (87 males and 81 females) were tested using pure-moment loading, simulating flexion-extension, lateral bending, and axial rotation. Axial compression tests were performed on 38 of the specimens. Sex, age, and BMI were analyzed with biomechanical parameters using 1-way ANOVA, Pearson correlation, and multiple regression analyses. MR images were obtained in 12 specimens (8 from obese and 4 from nonobese donors) using a 3-T MR scanner. RESULTS The segments from the obese male group allowed significantly greater range of motion (ROM) than those from the nonobese male group during axial rotation (p = 0.018), while there was no difference between segments from obese and nonobese females (p = 0.687). There were no differences in ROM between spines from obese and nonobese donors during flexion-extension or lateral bending for either sex. In the nonobese population, the ROM during axial rotation was significantly greater for females than for males (p = 0.009). There was no significant difference between sexes in the obese population (p = 0.892). Axial compressive stiffness was significantly greater for the obese than the nonobese population for both the female-only group and the entire study group (p < 0.01); however, the difference was nonsignificant in the male population (p = 0.304). Correlation analysis confirmed a significant negative correlation between BMI and resistance to deformation during axial compression in the female group (R = −0.65, p = 0.004), with no relationship in the male group (R = 0.03, p = 0.9). There was also a significant negative correlation between ROM during flexion-extension and BMI for the female group (R = −0.38, p = 0.001), with no relationship for the male group (R = 0.06, p = 0.58). Qualitative analysis using MR imaging indicated greater facet degeneration and a greater incidence of disc herniations in the obese group than in the control group. CONCLUSIONS Based on flexibility and compression tests, lumbar spinal segments from obese versus nonobese donors seem to behave differently, biomechanically, during axial rotation and compression. The differences are more pronounced in women. MR imaging suggests that these differences may be due to greater facet degeneration and an increased amount of disc herniation in the spines from obese individuals.


2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Zenghui Wang ◽  
Dongmei Wang ◽  
Linfang Huang

The contents of ferulic acid, senkyunolide A, butylidenephthalide, ligustilide, and n-butylphthalide were determined by UPLC analytical method; the correlation among the grade, average weight, and content was explored by correlation analysis and analysis of variance (ANOVA); the different commercial grades with average weight and content were revealed by principal component analysis (PCA) and then rationality analysis grade classification ofA. sinensis. The results showed that various commercial grades can be distinguished by PCA analysis. And there was significant negative correlation between the commodity grades and average weight, commodity, and the content of bioactive compounds, while the content of senkyunolide A had significant negative correlation with commodity grades (P<0.01). Average weight had no correlation with chemicals compounds. Additionally, there was significant positive correlation among the bioactive compounds (content of ferulic acid and phthalides) of different grades ofA. sinensis. The content of senkyunolide A, butylidenephthalide, and ligustilide had significant positive correlation with the content of ferulic acid. The content of ligustilide and butylidenephthalide had significant positive correlation with the content of senkyunolide A. The content of ligustilide had significant positive correlation with the content of butylidenephthalide. The basis of grades classification is related with the difference levels of the bioactive compounds.


2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S648-S648
Author(s):  
J Amoedo Cibeira ◽  
S Ramió-Pujol ◽  
M Serra-Pagès ◽  
A Bahí ◽  
C Puig-Amiel ◽  
...  

Abstract Background Crohn disease (CD) and Ulcerative colitis (UC) are characterised by episodes of exacerbations and remissions. Monitoring disease activity based on intestinal lesion is mandatory prior to any change in the therapeutic strategy. Colonoscopy is the gold standard technique to monitor the disease activity in IBD patients, but it is usually discarded because of costs and risk issues. The concentration of Faecal Calprotectin (FC) is widely used as a non-invasive marker of inflammation of the intestinal mucosa, allowing the assessment of the disease activity. Recently, different studies have demonstrated that certain microbial species, part of intestinal microbiota which can be detected in stool samples, are capable of correlating with disease activity in CD and UC patients. The purpose of this study was to analyse the correlation between these microbial indicators and the FC to monitor the disease activity in CD and UC patients. Methods FC levels were used to define inflammatory disease activity, the predetermined cut-off of 250 μg/g of faeces was used, higher values indicated an active inflammation and lower values indicated disease in remission. Two cohorts consisting of 61 patients of CD (25 with active inflammation and 36 with remission) and 90 of UC (42 with active inflammation and 48 with remission) were recruited by the Gastroenterology department of 4 Catalan hospitals. A sample of faeces was collected from each patient. FC and the following markers were quantified by qPCR: Faecalibacterium prausnitzii (Fpra), Escherichia coli (Eco), Akkermansia muciniphila (Akk), Ruminococcus sp. (Rum), Bacteroidetes (Bac) and Methanobrevibacter smithii (Msm) for each sample. Results The bacterial markers presented different behaviour depending on the disease analysed. The abundances of Eco and Bac were higher in CD with active inflammation compared with CD with remission. In contrast, no significant differences were found for Fpra, Akk, Rum, and Msm. Besides, a significant positive correlation between Eco abundance and FC levels (0.280, p = 0.029) and a significant negative correlation between Msm and FC levels (−0.299, p = 0.021) were observed. According UC patients, while the abundance of Eco was higher in patients with active inflammation, the abundance of Rum was significantly less abundant. No significant differences were found for Fpra, Akk, Bac, and Msm. Moreover, we also observed a significant negative correlation between Rum and FC levels (−0.308, p = 0.003, respectively). Conclusion The abundance of Eco and Msm in CD patients and the abundance of Rum in UC patients correlate to FC in order to determine inflammatory disease activity. So, these markers can also be an accurate discriminator of active disease in CD and UC patients.


Water SA ◽  
2018 ◽  
Vol 44 (3 July) ◽  
Author(s):  
D Seal ◽  
RT Bown ◽  
AH Parker

Pit latrine contents can have varying consistencies that make the pits challenging to empty. It has been assumed that solids sink to the bottom of the pit with a more liquid layer above this and a scum on the top. This implies that it would be possible to remove the uppermost layers with a pump. However, recent studies have found alternative sludge profiles, including a thick crust on the top. This paper presents penetrometer data from a large number (109) of pit latrines in Kibera, Nairobi, Kenya. The penetrometer consists of a weight, dropped onto an anvil that drives a cone into the pit. The depth of penetration following each impact was measured. This was converted into plots of depth in the pits against penetration. Each pit was analysed using Spearman’s rank correlation coefficient, and categorised into positive or negative correlation, significant or non-significant. Significant, negative correlation was assumed to correspond to pits where the solids had sunk to the bottom. 38% of pits were classified in this way, which suggested that while it is common that the number of impacts required to penetrate the sludge increases with depth in the pit, this is not always the case. Pit emptiers should be prepared to deal with pits with a variety of sludge profiles, including those with a solids layer at the top.


1992 ◽  
Vol 13 (3) ◽  
pp. 209-218 ◽  
Author(s):  
Raymond D. Semlitsch ◽  
Robert D. Aldridge

AbstractFemale Tantilla coronata reach sexual maturity in the spring of their third calendar of life (about 21 months of age) at about 150 mm snout-vent length. Vitellogenesis occurs in the spring, ovulation in June and oviposition in June and early July. Both ovaries are fully functional despite the lack of a functional left oviduct. The number of vitellogenic follicles is correlated with snout-vent length, however, the number of eggs or corpora lutea are not correlated with snout-vent length. Mean litter size and percent of females reproductive varied between years. The difference in the expected litter size between snakes with vitellogenic follicles and snakes with oviducal eggs or corpora lutea is due to atresia of vitellogenic follicles. Coelomic fat mass of adults showed a significant negative correlation during the course of vitellogenesis. Fat mass increased significantly following oviposition, however, some females had low coelomic reserves in late summer.


2014 ◽  
Vol 21 (06) ◽  
pp. 1264-1271
Author(s):  
Qamar Qamar Mehboob ◽  
M.H Qazi ◽  
Muhammad Arif

Objectives: To see the consequences of diabetic macular edema as assessed by optical coherence tomography (OCT) and visual acuity (V/A). Design: A prospective observational study. Patients were selected by simple random technique. Duration: Jan 2012 - Dec 2013. Material and Methods: A total of one hundred patients (200 eyes) of ages forty two to sixty three years with an average age of 51.04 ± 6.26 years of either sex were included. All these patients were examined in the outpatient department and were diagnosed as diabetic with macular edema and no opacity in refractive media. Their V/A was checked. OCT was performed in the Diagnostic & Research Centre, Department of Ophthalmology, Allied Hospital, Faisalabad. Results: Out of 200 eyes on OCT our findings were Diffuse Retinal Thickening in 199 eyes (99.5%), Cystoid Macular Edema in 119 eyes (59.5%), Subretinal Fluid in 48 eyes (24%), Epiretinal Membrane in 15 eyes(7.5%), Vitreomacular Traction in 11 eyes (5.5%) and Taut Posterior Hyaloid Membrane in 4 eyes(2%). The visual acuity on the right side was 0.29±0.19 and on left side it was 0.38±0.11. The macular thickness was 437.10±82.57 microns on the right side and 414.01±69.35 microns on the left side. The best-corrected visual acuity was significantly correlated with central foveal thickness. Our results showed, on the right side, a significant negative correlation (correlation coefficient: -0.355, p<0.01) between them. On the left side, a significant negative correlation (correlation coefficient: -0.362, p<0.01) was recorded.


2021 ◽  
Vol 23 (2) ◽  
pp. 175-180
Author(s):  
RAJEEV KUMAR ◽  

The investigation was carried out at the Horticulture Research Farm of the B.B.A. University, Lucknow (UP), India during rabi season of 2017-18 and 2018-19 to. Study the correlation coefficient and path analysis in tomato (Solanum lycopersicum L.). The twenty genotypes were evaluated in randomized block design with three replication. Genotypic correlation coefficient was indicated that fruit yield (q ha-1) exhibited highly significant positive correlations with average fruit weight (1.042), fruits per plant (0.996), branches per plant (0.831) and fruits per cluster (0.749). It also registered significant negative correlation with days to 50 % flowering (-0.835). However, phenotypic correlation coefficient indicated that fruit yield (q ha-1) had highly significant positive correlations with fruits per plant (0.977), clusters per plant (0.893), average fruit weight (0.729) whereas, significant negative correlation with days to 50 % flowering (-0.178). Path analysis revealed that the traits like fruit yield kg/plot (1.430) and fruit yield per plant (0.034) exhibited positive direct effects on fruit yield and these traits also recorded positive correlation with yield. This suggested that direct selection based on these traits will be rewarding for crop yield improvement.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
H Amer ◽  
H Ghareeb ◽  
N L Mohamed ◽  
N O El-Azizi ◽  
A M Mansour

Abstract Background Rheumatoid Arthritis (RA) is a common autoimmune disease with a complex pathogenesis involving multiple genetic and environmental factors. The management of RA rests on several principles. Drug treatment, which comprises disease-modifying antirheumatic drugs (DMARDs), non-steroidal anti-inflammatory drugs and glucocorticoids (GCs), as well as non-pharmacological measures, such as physical, occupational and psychological therapeutic approaches, together may lead to therapeutic success. However, the mainstay of RA treatment is the application of DMARDs. Methotrexate is an antifolate and antimetabolite; it’s one of the DMARDs. Long term therapy with methotrexate has been associated with development of fatty liver and hepatic fibrosis. Liver biopsy is the standard method for diagnosing liver fibrosis, but it may be associated with significant morbidity and mortality of up to 0.33% thereby limiting its use. So the use of noninvasive markers of hepatic fibrosis such as serial platelet counts, FIB 4 score, ALT/AST ratio and recently serum PIIINP become mandatory. Objectives to evaluate the reliability of PIIINP in the screening for hepatic fibrosis induced by long term methotrexate therapy in rheumatoid arthritis patients compared with FIB 4 score and ALT/AST ratio. Patients and Methods This case study included 90 RA patients categorized into 60 RA patients on MTX therapy (group I), 30 RA patients on other medications (group II). All participants were subjected to full history taking, thorough rheumatological examination and lab investigations including complete blood count (CBC), ESR, CRP, AST, ALT, RF and measurement of serum PIINP levels, DAS and FIB-4 score were calculated. Results Patients in group I showed significant increase in serum PIIINP compared to patients in group II. There was significant negative correlation between disease duration, Platelets count and serum PIIINP levels in patients of both groups. There was significant negative correlation between folic acid intake and serum PIIINP levels of group I. There was significant positive correlation between Mean Corpuscular Volume, AST, ALT, AST/ALT ratio, FIB-4 score and serum PIIINP levels in patients of both groups. There was significant positive correlation between MTX dose and duration and levels of serum PIIINP in patients of group I. Conclusion Serum PIIINP levels could be used as non invasive marker for screening for hepatic fibrosis induced by long term MTX therapy in RA patients.


Author(s):  
Mohammed A. Saker ◽  
Shereef L. Elshwaikh ◽  
Ayman A. Eldorf ◽  
Manal M. AbdAlla

Background: Placenta accrete occurs when there is abnormal attachment of the placenta to the uterine wall either partially or totally. Placenta accreta had many complications mainly intraoperative and postpartum including injury to local organs (e.g. bowel, bladder, ureters) and neurovascular structures in the retroperitoneum. The aim of the present study was to evaluate the uterine cavity after conservative management of placenta accreta by using hysteroscope. Materials and Methods: This is prospective study was carried on 40 pregnant at Tanta University Hospital with age >35 years, to detect Presence or absence of intra uterine changes after conservative management of placenta accrete by hysteroscopy, easiness of performing diagnostic hysteroscopy and Correlation between intrauterine changes and operative data. Results: Hysteroscopic examination of the participants showed that 30.0% with incidences of Cervical stenosis, 15.0% with uterine cavity irregularity, 15.0% with intrauterine adhesions, 10.0% with endometrial fibrosis, 5.0% with scar dehiscence and 5.0% with Remnant. There was a statistically significant positive correlation between development of cervical stenosis and endometrial thickness by US (correlation coefficient r = 0.323 with p value 0.042) .There was a statistically significant negative correlation between Endometrial fibrosis and scar thickness (correlation coefficient r = -0.538 with p value <0.001). There was a statistically significant negative correlation between Intra uterine adhesions and scar thickness (correlation coefficient r = -0.470 with p value 0.002). There was a statistically significant negative correlation between uterine cavity irregularity and duration of CS  (correlation coefficient r = -0.320 with p value 0.044). Conclusion: The frequency of abnormal hysteroscopic findings after conservative management of placenta accreta is high, for at least several months after the procedure. The most frequently found abnormalities, associated with conservative treatment, are cervical stenosis, uterine cavity irregularity and Intrauterine adhesions.


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