scholarly journals Klasifikasi Alzheimer dan Non Alzheimer Menggunakan Fuzzy C-Mean, Gray Level Co-Occurence Matrix dan Support Vector Machine

2018 ◽  
Vol 4 (2) ◽  
pp. 83-89
Author(s):  
Dian C. Rini Novitasari
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Support Vector Machine ◽  
Cognitive Disorders ◽  
Support Vector ◽  
Gray Level ◽  
Accuracy Result ◽  
Magnetic Resonance Imaging Mri ◽  
Occurrence Matrix ◽  
Patients Experience

Based on the Alzheimer's Charter, 2-3 million cases of dementia by Alzheimer's disease occur every year. People with Alzheimer's disease experience memory and cognitive disorders progressively for 3 to 9 years. Patients experience confusion in understanding the question and have a chaotic sequence of memory, which can interfere with daily activities and unchecked well, it cause death. The classification system is based on Alzheimer's and non-Alzheimer's disease Magnetic Resonance Imaging (MRI) using Support Vector Machine (SVM). The feature data segmentation using Fuzzy C-Means (FCM) and feature extraction using Gray Level Co-Occurrence Matrix (GLCM) and give accuracy result of 93.33%.

scholarly journals Classification of Alzheimer’s Disease Patients Using Texture Analysis and Machine Learning

2021 ◽  
Vol 4 (3) ◽  
pp. 49
Author(s):  
Sumit Salunkhe ◽  
Mrinal Bachute ◽  
Shilpa Gite ◽  
Nishad Vyas ◽  
Saanil Khanna ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Complex Disease ◽  
Texture Classification ◽  
Region Of Interest ◽  
Structural Data ◽  
Support Vector ◽  
Magnetic Resonance Imaging Mri ◽  
The Many ◽  
Occurrence Matrix

Alzheimer’s disease (AD) has been studied extensively to understand the nature of this complex disease and address the many research gaps concerning prognosis and diagnosis. Several studies based on structural and textural characteristics have already been conducted to aid in identifying AD patients. In this work, an image processing methodology was used to extract textural information and classify the patients into two groups: AD and Cognitively Normal (CN). The Gray Level Co-occurrence Matrix (GLCM) was employed since it is a strong foundation for texture classification. Various textural parameters derived from the GLCM aided in deciphering the characteristics of a Magnetic Resonance Imaging (MRI) region of interest (ROI). Several commonly used image classification algorithms were employed. MATLAB was used to successfully derive 20 features based on the GLCM of the MRI dataset. Based on the data analysis, 8 of the 20 features were determined as significant elements. Ensemble (90.2%), Decision Trees (88.5%), and Support Vector Machine (SVM) (87.2%) were the best performing classifiers. It was observed in GLCM that as the distance (d) between pixels increased, the classification accuracy decreased. The best result was observed for GLCM with d = 1 and direction (d, d, −d) with age and structural data.

scholarly journals To Explore the Predictive Power of Visuomotor Network Dysfunctions in Mild Cognitive Impairment and Alzheimer’s Disease

2021 ◽  
Vol 15 ◽  
Author(s):  
Justine Staal ◽  
Francesco Mattace-Raso ◽  
Hennie A. M. Daniels ◽  
Johannes van der Steen ◽  
Johan J. M. Pel
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Support Vector Machine ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Predictive Power ◽  
Area Under The Curve ◽  
Classification Performance ◽  
Support Vector ◽  
Potential Biomarker

BackgroundResearch into Alzheimer’s disease has shifted toward the identification of minimally invasive and less time-consuming modalities to define preclinical stages of Alzheimer’s disease.MethodHere, we propose visuomotor network dysfunctions as a potential biomarker in AD and its prodromal stage, mild cognitive impairment with underlying the Alzheimer’s disease pathology. The functionality of this network was tested in terms of timing, accuracy, and speed with goal-directed eye-hand tasks. The predictive power was determined by comparing the classification performance of a zero-rule algorithm (baseline), a decision tree, a support vector machine, and a neural network using functional parameters to classify controls without cognitive disorders, mild cognitive impaired patients, and Alzheimer’s disease patients.ResultsFair to good classification was achieved between controls and patients, controls and mild cognitive impaired patients, and between controls and Alzheimer’s disease patients with the support vector machine (77–82% accuracy, 57–93% sensitivity, 63–90% specificity, 0.74–0.78 area under the curve). Classification between mild cognitive impaired patients and Alzheimer’s disease patients was poor, as no algorithm outperformed the baseline (63% accuracy, 0% sensitivity, 100% specificity, 0.50 area under the curve).Comparison with Existing Method(s)The classification performance found in the present study is comparable to that of the existing CSF and MRI biomarkers.ConclusionThe data suggest that visuomotor network dysfunctions have potential in biomarker research and the proposed eye-hand tasks could add to existing tests to form a clear definition of the preclinical phenotype of AD.

scholarly journals Accelerating Hyperparameter Tuning in Machine Learning for Alzheimer’s Disease With High Performance Computing

2021 ◽  
Vol 4 ◽  
Author(s):  
Fan Zhang ◽  
Melissa Petersen ◽  
Leigh Johnson ◽  
James Hall ◽  
Sid E. O’Bryant
Keyword(s):  
Machine Learning ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
High Performance ◽  
Support Vector ◽  
Massive Datasets ◽  
Complexity Of Algorithms ◽  
Magnetic Resonance Imaging Mri ◽  
Research Challenge ◽  
Improved Accuracy

Driven by massive datasets that comprise biomarkers from both blood and magnetic resonance imaging (MRI), the need for advanced learning algorithms and accelerator architectures, such as GPUs and FPGAs has increased. Machine learning (ML) methods have delivered remarkable prediction for the early diagnosis of Alzheimer’s disease (AD). Although ML has improved accuracy of AD prediction, the requirement for the complexity of algorithms in ML increases, for example, hyperparameters tuning, which in turn, increases its computational complexity. Thus, accelerating high performance ML for AD is an important research challenge facing these fields. This work reports a multicore high performance support vector machine (SVM) hyperparameter tuning workflow with 100 times repeated 5-fold cross-validation for speeding up ML for AD. For demonstration and evaluation purposes, the high performance hyperparameter tuning model was applied to public MRI data for AD and included demographic factors such as age, sex and education. Results showed that computational efficiency increased by 96%, which helped to shed light on future diagnostic AD biomarker applications. The high performance hyperparameter tuning model can also be applied to other ML algorithms such as random forest, logistic regression, xgboost, etc.

scholarly journals A Comparative Analysis of Machine Learning Algorithms to Predict Alzheimer’s Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Morshedul Bari Antor ◽  
A. H. M. Shafayet Jamil ◽  
Maliha Mamtaz ◽  
Mohammad Monirujjaman Khan ◽  
Sultan Aljahdali ◽  
...  
Keyword(s):  
Machine Learning ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Support Vector Machine ◽  
Machine Learning Algorithms ◽  
Learning System ◽  
Fine Tuning ◽  
Support Vector ◽  
Learning Models ◽  
Machine Learning Models

Alzheimer’s disease has been one of the major concerns recently. Around 45 million people are suffering from this disease. Alzheimer’s is a degenerative brain disease with an unspecified cause and pathogenesis which primarily affects older people. The main cause of Alzheimer’s disease is Dementia, which progressively damages the brain cells. People lost their thinking ability, reading ability, and many more from this disease. A machine learning system can reduce this problem by predicting the disease. The main aim is to recognize Dementia among various patients. This paper represents the result and analysis regarding detecting Dementia from various machine learning models. The Open Access Series of Imaging Studies (OASIS) dataset has been used for the development of the system. The dataset is small, but it has some significant values. The dataset has been analyzed and applied in several machine learning models. Support vector machine, logistic regression, decision tree, and random forest have been used for prediction. First, the system has been run without fine-tuning and then with fine-tuning. Comparing the results, it is found that the support vector machine provides the best results among the models. It has the best accuracy in detecting Dementia among numerous patients. The system is simple and can easily help people by detecting Dementia among them.

scholarly journals Prediction of Alzheimer’s Disease Using Machine Learning Classifiers

2020 ◽  
Vol 9 (3) ◽  
pp. 116-120
Author(s):  
Mansour Rezaei ◽  
Ehsan Zereshki ◽  
Soodeh Shahsavari ◽  
Mohammad Gharib Salehi ◽  
Hamid Sharini
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Correct Diagnosis ◽  
Medical Science ◽  
Screening Tests ◽  
Support Vector ◽  
Svm Classifier ◽  
Rbf Kernel ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Background: Alzheimer’s disease (AD) is the most common brain failure for which no cure has yet been found. The disease starts with a disturbance in the brain structure and then it manifests itself clinically. Therefore, by timely and correct diagnosis of changes in the structure of the brain, the occurrence of this disease or at least its progression can be prevented. Due to the fact that magnetic resonance imaging (MRI) can be used to obtain very useful information from the brain, and also because it is non-invasive, this method has been considered by researchers. Materials and Methods: The data were obtained from an MRI database (MIRIAD) of 69 subjects including 46 AD patients and 23 healthy controls (HC). Individuals were categorized based on two criteria including NINCDS-ADRAD and MMSE, as the gold standard. In this paper, we used the support vector machine (SVM) and Bayesian SVM classifiers. Results: Using the SVM classifier with Gaussian radial basis function (RBF) kernel, we distinguished AD and HC with an accuracy of 88.34%. The most important regions of interest (ROIs) in this study included right para hippocampal gyrus, left para hippocampal gyrus, right hippocampus, and left hippocampus. Conclusion: This study showed that the SVM model with Gaussian RBF kernel can distinguish AD from HC with high accuracy. These studies are of great importance in medical science. Based on the results of this study, MRI centers and neurologists can perform AD screening tests in people over the age of 50 years.

scholarly journals Digit Classification of Majapahit Relic Inscription using GLCM-SVM

2018 ◽  
Vol 1 (2) ◽  
pp. 46
Author(s):  
Tri Septianto ◽  
Endang Setyati ◽  
Joan Santoso
Keyword(s):  
Image Processing ◽  
Support Vector Machine ◽  
Feature Extraction ◽  
Template Matching ◽  
Support Vector ◽  
Gray Level ◽  
Class 1 ◽  
Occurrence Matrix ◽  
Handwritten Recognition

A higher level of image processing usually contains some kind of classification or recognition. Digit classification is an important subfield in handwritten recognition. Handwritten digits are characterized by large variations so template matching, in general, is inefficient and low in accuracy. In this paper, we propose the classification of the digit of the year of a relic inscription in the Kingdom of Majapahit using Support Vector Machine (SVM). This method is able to cope with very large feature dimensions and without reducing existing features extraction. While the method used for feature extraction using the Gray-Level Co-Occurrence Matrix (GLCM), special for texture analysis. This experiment is divided into 10 classification class, namely: class 1, 2, 3, 4, 5, 6, 7, 8, 9, and class 0. Each class is tested with 10 data so that the whole data testing are 100 data number year. The use of GLCM and SVM methods have obtained an average of classification results about 77 %.

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