EXCORNSEED EU Project: Separation, Fractionation and Isolation of Biologically Active Natural Substances from Corn Oil and Other Side Streams to Be Used in Food, Specialty Chemicals and Cosmetic Markets

The EXCornsEED project combines science, chemistry, biology, engineering and biotechnology tools and knowledge, to develop and validate an integrated process of innovative and highly sustainable extraction/ purification and concentration technologies being integrated in bio-refineries’ side streams in order to recover, characterise and prepare proteins and other bio-active compounds (i.e. peptides, polyphenols, amino acids, fibres, lipid compounds) as ingredients for food, specialty chemicals and cosmetic market. The approach will be upscaled from lab level (few grams, TRL3) up to industrial pilot level (1t/d capacity, TRL5) considering EU strategies for a bio-based economy to transform traditional bioethanol production into future biorefinery concept as well as circular economy, in order to maximize the utilization of industrial by-products.

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Sustainable Extraction and Use of Natural Bioactive Compounds from the Waste Management Process of Castanea spp. Bud-Derivatives: The FINNOVER Project

Sustainability ◽

10.3390/su122410640 ◽

2020 ◽

Vol 12 (24) ◽

pp. 10640

Author(s):

Dario Donno ◽

Federica Turrini ◽

Raffaella Boggia ◽

Maddalena Guido ◽

Giovanni Gamba ◽

...

Keyword(s):

Waste Management ◽

Bioactive Compounds ◽

Value Added ◽

Total Content ◽

Biologically Active ◽

Management Process ◽

Ultrasound Assisted Extraction ◽

Green Extraction ◽

Sustainable Extraction ◽

By Products

The FINNOVER project provides a technical and economic path for the creation of new supply chains, or their development, for the sustainable extraction and utilization of natural biologically active molecules. In this research, a green extraction method and re-use strategy of botanical by-products are developed and used to obtain value-added products as an ecological alternative to waste composting or incineration. It was applied to the production of Castanea spp. bud-derivatives (a specific category of food supplements derived from plant material) and their by-products. This study aimed to compare the phytochemical composition of Castanea spp. bud-preparations (herbal preparations from buds and sprouts) with the extracts derived from the bud-waste management process. Bioactive compounds were extracted by maceration in hydroglyceroalcoholic solution (traditional method) and by a green extraction technique (Pulsed Ultrasound-Assisted Extraction—PUAE) and identified and quantified by HPLC methods obtaining a specific chromatographic profile. PUAE extracted a total content of 160.42 mg/100 g FW, a good amount if compared to the relative commercial product (1276.17 mg/100 g FW). About 13% of the chemical content of Castanea spp. bud-preparations was maintained in the by-product extracts. This research showed that PUAE may be considered as a sustainable alternative to waste management based on incineration or composting. This study could be considered by the industries for the development of new products for the market derived from the bud-derivative processing waste.

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ChemInform Abstract: Synthesis of Biologically Active Natural Substances

ChemInform ◽

10.1002/chin.198829345 ◽

1988 ◽

Vol 19 (29) ◽

Author(s):

R. VLAKHOV ◽

D. KRIKORYAN ◽

V. TARPANOV ◽

G. SPASOV ◽

G. SNATZKE ◽

...

Keyword(s):

Biologically Active ◽

Natural Substances ◽

Active Natural

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Secondary Metabolites, Dietary Fiber and Conjugated Fatty Acids as Functional Food Ingredients against Overweight and Obesity

Natural Product Communications ◽

10.1177/1934578x1801300836 ◽

2018 ◽

Vol 13 (8) ◽

pp. 1934578X1801300 ◽

Cited By ~ 8

Author(s):

Kamila Kasprzak ◽

Karolina Wojtunik-Kulesza ◽

Tomasz Oniszczuk ◽

Maciej Kuboń ◽

Anna Oniszczuk

Keyword(s):

Functional Food ◽

Overweight And Obesity ◽

Biologically Active ◽

Food Ingredients ◽

Conjugated Fatty Acids ◽

Natural Substances ◽

Optimal Health ◽

Positive Effect ◽

Interesting Solution ◽

Active Natural

Obesity is a common serious health problem leading to many serious health disorders. This phenomenon is defined as the over-storage of lipids in adipose tissue that occurs when there is an imbalance between the energy intake and energy used. During obesity, many metabolic alterations occur that can damage several organs, such as vascular or skeletal muscle resulting in the dysfunction of these tissues. In this review, we will discuss molecular genetics and causes of obesity, some of the disorders related to human obesity as well as anti-obesity tool. An interesting solution to the obesity problem is natural substances, revealing anti-obesity activity, as well as functional food enriched with aforementioned substances. Functional foods are products exhibiting a potentially positive effect on health beyond basic nutrition. They contain well-known biologically active natural compounds, which promote optimal health and reduce the risk of many diseases, including obesity.

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Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil

Foods ◽

10.3390/foods11020153 ◽

2022 ◽

Vol 11 (2) ◽

pp. 153

Author(s):

Francesco Cairone ◽

Stefania Cesa ◽

Alessia Ciogli ◽

Giancarlo Fabrizi ◽

Antonella Goggiamani ◽

...

Keyword(s):

Corn Oil ◽

Solid Phase ◽

Biological Activities ◽

Selective Extraction ◽

Bioactive Molecules ◽

Total Phenolic ◽

Extraction And Purification ◽

Sustainable Extraction ◽

By Products ◽

Hplc Analyses

The aim of this work was to develop innovative and sustainable extraction, concentration, and purification technologies aimed to recover target substances from corn oil, obtained as side stream product of biomass refineries. Residues of bioactive compounds such as carotenoids, phytosterols, tocopherols, and polyphenols could be extracted from this matrix and applied as ingredients for food and feeds, nutraceuticals, pharmaceuticals, and cosmetic products. These molecules are well known for their antioxidant and antiradical capacity, besides other specific biological activities, generically involved in the prevention of chronic and degenerative diseases. The project involved the development of methods for the selective extraction of these minor components, using as suitable extraction technique solid phase extraction. All the extracted and purified fractions were evaluated by NMR spectroscopic analyses and UV–Vis spectrophotometric techniques and characterized by quali-quantitative HPLC analyses. TPC (total phenolic content) and TFC (total flavonoid content) were also determined. DPPH and ABTS radical were used to evaluate radical quenching abilities. Acetylcholinesterase (AChE), amylase, glucosidase, and tyrosinase were selected as enzymes in the enzyme inhibitory assays. The obtained results showed the presence of a complex group of interesting molecules with strong potential in market applications according to circular economy principles.

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Biologically active natural products from Cassine viburnifolia

Planta Medica ◽

10.1055/s-0035-1556259 ◽

2015 ◽

Vol 81 (11) ◽

Author(s):

T Grkovic ◽

R Akee ◽

J Evans ◽

JM Collins ◽

B O'Keefe

Keyword(s):

Natural Products ◽

Biologically Active ◽

Active Natural

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Monomers, Materials and Energy from Coffee By-Products: A Review

Sustainability ◽

10.3390/su13126921 ◽

2021 ◽

Vol 13 (12) ◽

pp. 6921

Author(s):

Laura Sisti ◽

Annamaria Celli ◽

Grazia Totaro ◽

Patrizia Cinelli ◽

Francesca Signori ◽

...

Keyword(s):

Circular Economy ◽

Food Industry ◽

Food Packaging ◽

Low Cost ◽

Biofuel Production ◽

Material Technology ◽

Coffee Production ◽

Coffee Pulp ◽

Coffee Waste ◽

By Products

In recent years, the circular economy and sustainability have gained attention in the food industry aimed at recycling food industrial waste and residues. For example, several plant-based materials are nowadays used in packaging and biofuel production. Among them, by-products and waste from coffee processing constitute a largely available, low cost, good quality resource. Coffee production includes many steps, in which by-products are generated including coffee pulp, coffee husks, silver skin and spent coffee. This review aims to analyze the reasons why coffee waste can be considered as a valuable source in recycling strategies for the sustainable production of bio-based chemicals, materials and fuels. It addresses the most recent advances in monomer, polymer and plastic filler productions and applications based on the development of viable biorefinery technologies. The exploration of strategies to unlock the potential of this biomass for fuel productions is also revised. Coffee by-products valorization is a clear example of waste biorefinery. Future applications in areas such as biomedicine, food packaging and material technology should be taken into consideration. However, further efforts in techno-economic analysis and the assessment of the feasibility of valorization processes on an industrial scale are needed.

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Valorization of Kiwi by-Products for the Recovery of Bioactive Compounds: Circular Economy Model

Proceedings ◽

10.3390/foods_2020-07647 ◽

2020 ◽

Vol 70 (1) ◽

pp. 9

Author(s):

Franklin Chamorro ◽

María Carpena ◽

Bernabé Nuñez-Estevez ◽

Miguel A. Prieto ◽

Jesus Simal-Gandara

Keyword(s):

Bioactive Compounds ◽

Circular Economy ◽

Agricultural Production ◽

Organic Waste ◽

Antimicrobial Activities ◽

Added Value ◽

Economic Returns ◽

Industrial Processing ◽

Pharmaceutical Industries ◽

By Products

Currently, agricultural production generates large amounts of organic waste, both from the maintenance of farms and crops, and from the industrialization of the product. Generally, these wastes are accumulated in landfills or burned, sometimes causing environmental problems. However, many scientific studies suggest that these residues are rich in bioactive compounds, so these matrices could be revalued for their use in food, cosmetic, or pharmaceutical industries. In this way, the circular and sustainable economy is favored, while obtaining products with high added value. In this case, this approach is applied to the residues generated from kiwi production, since numerous studies have shown the high content of kiwi in bioactive compounds of interest, such as phenolic compounds, vitamins, and carotenoids. These compounds have been reported for their antioxidant, anti-inflammatory, and antimicrobial activities, among other beneficial properties for health such as its use as prebiotic. Therefore, this article reviews the potential of residues derived from industrial processing and agricultural maintenance of kiwi as promising matrices for the development of new nutraceutical, cosmetic, or pharmacological products, obtaining, at the same time, economic returns and a reduction of the environmental impact of this industry, attaching it to the perspective of the circular economy.

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A review on the production, structure, bioactivities and applications of Tremella polysaccharides

International Journal of Immunopathology and Pharmacology ◽

10.1177/20587384211000541 ◽

2021 ◽

Vol 35 ◽

pp. 205873842110005

Author(s):

Xia Ma ◽

Meng Yang ◽

Yan He ◽

Chuntao Zhai ◽

Chengliang Li

Keyword(s):

Biologically Active ◽

Research Progress ◽

Research Trend ◽

Production Structure ◽

Health States ◽

Preparation Methods ◽

The Past ◽

Structure Activity ◽

Relationship Of ◽

Active Natural

Tremella polysaccharide is known to be structurally unique and biologically active natural products, abundant and versatile in activities and applications in food industry, daily chemical industry and medicine industry. In order to improve the industrialisation of Tremella polysaccharide, the limitations of preparation and structure-activity relationship of Tremella polysaccharide were reviewed in this paper. The research progress of Tremella polysaccharide in the past 20 years was summarized from the sources, preparation methods, molecular structure, activity and application, and the research trend in the future was also prospected. The application prospect of Tremella polysaccharide in against multiple sub-health states was worth expecting.

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Sustainability: Recovery and Reuse of Brewing-Derived By-Products

Sustainability ◽

10.3390/su13042355 ◽

2021 ◽

Vol 13 (4) ◽

pp. 2355

Author(s):

Tiziana Amoriello ◽

Roberto Ciccoritti

Keyword(s):

Circular Economy ◽

Inclusive Growth ◽

Global Challenge ◽

Use Of Resources ◽

By Products ◽

Recovery And Reuse

The great global challenge in order to achieve sustainable and inclusive growth over the coming decades is the promotion of the efficient use of resources, favoring a transition to a cleaner and circular economy [...]

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