scholarly journals Sweet Taste Threshold among Medical Students with Family History of Diabetes Mellitus

2020 ◽  
Vol 7 (4) ◽  
Author(s):  
Nasya Aisah Latif ◽  
Yulia Sofiatin ◽  
Maya Kusumawati ◽  
Rully Marsis Amirullah Roesli
Keyword(s):  
Diabetes Mellitus ◽  
Medical Students ◽  
Family History ◽  
Sweet Taste ◽  
Diabetic Patients ◽  
Taste Threshold ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
History Of

Background: Diabetic patients have low sensitivity towards sweet taste, thus consuming more sugar. A young adult with family history of diabetes mellitus (FHD) who lives with diabetic parents may have an increased risk of overconsumption of sugar due to a similar dietary pattern, leading to diabetes. This study aimed to explore the difference in the sweet taste threshold (STT) between students with and without a family history of diabetes mellitus. Methods: This cross-sectional study was conducted in October –November 2018 on Class 2018 medical students living in a student dormitory who were divided into those with family history of diabetes (FHD) and those without it (non-FHD). Family history of diabetes and other known diseases were self-reported. The three-Ascending Forced Choice method was used to determine the sweet recognition threshold. Mann-Whitney analysis was used to compare the sweet taste thresholds between the two groups. Result: A total of 183 subjects participated in this study. The non-FHD group had a higher rank of sweet taste threshold than subjects in the FHD group (94.21 vs 81.16), albeit insignificant (p=0.192). Interestingly, the modes of best estimation threshold (BET) for non-FHD group was than the FHD group (0.067 M vs 0.043 M). Conclusion: The BET for students without family history of diabetes is higher than those with family history of diabetes. It is imperative that low sugar consumption campaign should also aim young people without FHD.

scholarly journals Assessment of plasma blood sugar level in first degree relatives of known type 2 diabetes patients: a descriptive study from Maharashtra, India

2020 ◽  
Vol 7 (3) ◽  
pp. 482
Author(s):  
J. K. Deshmukh ◽  
P. Y. Mulay ◽  
Amit G. Naghate ◽  
Anant A. Takalkar
Keyword(s):  
Family History ◽  
Health Check ◽  
Steady Increase ◽  
Diabetic Patients ◽  
Maternal History ◽  
Family History Of Diabetes ◽  
First Degree Relatives ◽  
Increased Risk ◽  
History Of

Background: There is steady increase in the prevalence of diabetes mellitus from 0.73% to current 2.4% in rural and 4.0% to 11.6% in urban areas. Familial clustering of diabetes may support a genetic predisposition to diabetes. With increase in the prevalence of diabetes there is increase in number of first degree relative as well, thus an increased risk of developing diabetes, will also increase. To study the plasma glucose levels in First-degree relatives of family member of type 2 diabetic patients was the objective of the present study.Methods: It is a descriptive observational study with 1020 individuals serially coming to our outpatient Department for Pre-employment Medical Health Check Up Annual Health Check Up were selected. These individuals have been enrolled for the study and their family history of diabetes was noted, their sugar levels and their lipid levels were estimated and their body mass index was calculated. The data thus collected and analyzed with excel.Results: 184 (18%) individuals were FDRs, were as 836 (82%) individuals were Non-FDRs. There were 754 (74%) males [131(17%) FDR and 623(83%) Non-FDR], were as 213 (26%) females [53(20%) FDR and 213(80%) Non-FDR], 61(6%) individuals were having Diabetic Mother, 91(9%) individuals had Diabetic Father and 32(3%) were those in whom both the Parents were Diabetic. It was found that maternal history has strong association for getting abnormal BSL levels as compared to a diabetic father as the RR of 9.82 (95% 4.84 to 19.95) in individuals with mother being diabetic, and RR of 1.54(95% 0.68 to 3.87) of father being diabetic.Conclusions: Family history of diabetes, maternal history of diabetes and history of both the parents having diabetes are risk factors for diabetes in FDRs.

scholarly journals The prevalence of insulin resistance in patients with β -thalassemia major at Cipto Mangunkusumo Hospital

2016 ◽  
Vol 43 (4) ◽  
pp. 117
Author(s):  
Caroline Mulawi ◽  
Bambang Tridjaja ◽  
Maria Abdulsalam ◽  
Zakiudin Munasir
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Family History ◽  
Glucose Metabolism ◽  
Thalassemia Major ◽  
Oral Glucose ◽  
Model Assessment ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Background Diabetes mellitus is a common complication in pa-tients with thalassemia major. Iron overload plays an important roleby damaging the pancreatic β-cell and the liver cell, with the con-sequences of insulin deficiency and insulin resistance. Family his-tory of diabetes mellitus is one of the critical factors for the devel-opment of glucose metabolism derangement. However, the patho-genesis of glucose metabolism derangement remains unclear.Objective To evaluate the prevalence of impaired glucose toler-ance, diabetes mellitus, and insulin resistance in patients with β-thalassemia major treated in the Thalassemia Outpatient Clinic,Department of Child Health, Cipto Mangunkusumo Hospital,Jakarta.Methods This was a descriptive cross sectional study conductedin May 2002. Forty-eight subjects aged 10 to 18 years, grouped bytotal volume of transfusions and family history of diabetes mellitus,underwent an oral glucose tolerance test (OGTT), serum transfer-rin saturation, and insulin level examinations. Insulin resistancewas calculated from fasting plasma glucose and insulin concen-trations using the homeostasis model assessment (HOMA).Results One of 48 patients (2%) had impaired glucose toleranceat the age of 17 years. Diabetes mellitus occurred in three of 48patients (6%) at the age of 15.5 years in one patient and 18 yearsin two patients. Family history of diabetes mellitus was found in 2patients with diabetes mellitus and in the only one with impairedglucose tolerance. Insulin resistance was not detected in this study.Conclusion The prevalence of glucose metabolism derangementin patients with thalassemia major was low. No insulin resistancewas found in this study

FAMILY HISTORY OF DIABETES IS ASSOCIATED WITH INCREASED RISK OF RECURRENT DIABETIC KETOACIDOSIS IN PEDIATRIC PATIENTS

2020 ◽  
Vol 26 (3) ◽  
pp. 305-311
Author(s):  
Janaki D. Vakharia ◽  
Sungeeta Agrawal ◽  
Janine Molino ◽  
Lisa Swartz Topor
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Diabetic Ketoacidosis ◽  
Pediatric Patients ◽  
Incidence Rate Ratio ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
History Of

Objective: To determine the relationship between family history of diabetes mellitus (DM) and diabetic ketoacidosis (DKA) recurrence in youth with established type 1 diabetes mellitus (T1DM). Methods: We performed a retrospective chart review of patients with DKA admitted to a pediatric hospital between January, 2009, and December, 2014. We compared patients with recurrent (≥2 admissions) and nonrecurrent DKA (1 admission) and investigated patient level factors, including family history, that may be associated with DKA recurrence in pediatric patients with established T1DM. Results: Of the 131 subjects in the study, 51 (39%) subjects were in the recurrence group. Age ≥15 years old, public health insurance, and family history of T1DM or type 2 diabetes mellitus were associated with recurrent DKA admissions in both univariable and multivariable analyses. Family history was associated with DKA recurrence, with an incidence rate ratio of 1.5 (95% confidence interval = 1.0 to 2.3; P = .03). The association was not explained by type of familial diabetes, first degree relative status, or whether the family member lived in the household. Conclusion: Recognition that a positive family history of DM may be associated with a higher risk for DKA recurrence in patients with established T1DM may allow for targeted education and focus on a previously unidentified population at increased risk for DKA. Understanding the mechanism underlying the effect of family history of diabetes on the rates of DKA in patients with established T1DM may allow for improved identification and education of patients who may be at risk for DKA recurrence. Abbreviations: CI = confidence interval; DKA = diabetic ketoacidosis; EHR = electronic health record; IBD = inflammatory bowel disease; IRR = incidence rate ratio; T1DM = type 1 diabetes mellitus; T2DM = type 2 diabetes mellitus

scholarly journals A community based study on perceived knowledge of diabetes on cause, control, prevention and complications among diabetic patients in Bengaluru city

2017 ◽  
Vol 4 (9) ◽  
pp. 3416
Author(s):  
Shwetha . ◽  
K. N. Prasad
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Warning Signs ◽  
Diabetic Patients ◽  
Perceived Knowledge ◽  
Community Based ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Duration Of Diabetes ◽  
Intervention Measures

Background: The numbers of diabetes mellitus cases are increasing among all sections of Indian population. The knowledge about the disease, associated complications and co-morbidities are not satisfactory among the public including diabetic patients. The objective of the study was to assess the perceived knowledge and determining factors on onset, control, prevention and complications of diabetes mellitus in urban area of Bengaluru.Methods: A cross sectional, descriptive and community based study with a sample size 770 randomly selected known diabetics was conducted during May to July 2016 in Bengaluru city by direct interviewing them at their doorsteps using pretested questionnaire. The data contained information about the socio-demographic profile, knowledge about the warning signs, complications, controllability, consequences and co morbidities. Data was analysed in SPSS version 18.Results: There were 43.7% and 57.5% of males and females respectively. Seventy percent of females were homemakers and two third were literates. The maximum numbers of subjects were in the age group of 41-60 years with mean age of 56±11.6 years.  Family history of diabetes was present among 40%. The median duration of diabetes was 48 months (range 1 to 360) and 38% of the subjects had co morbid conditions related to cardiovascular diseases and other systems. The perceived knowledge related to prevention, complications, consequences and controllability of diabetes was not adequate in relation to their literacy status, family history and duration of diabetes. The overall perceived knowledge was better among females than male subjects.Conclusions: The perceived knowledge about the different aspects of diabetes care at the personal level of diabetics were inadequate and needs periodic counselling as intervention measures. 

scholarly journals Synergy of BMI and family history on diabetes: the Humboldt Study

2009 ◽  
Vol 13 (4) ◽  
pp. 461-465 ◽  
Author(s):  
Yue Chen ◽  
Donna C Rennie ◽  
James A Dosman
Keyword(s):  
Family History ◽  
Joint Effect ◽  
Cross Sectional Study ◽  
Additive Interaction ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Increased Risk ◽  
History Of ◽  
Associated Family ◽  
Diagnosed Diabetes

AbstractObjectiveTo examine the joint effect of family history and BMI on diabetes.DesignCross-sectional study.SettingA rural community in Saskatchewan, Canada.SubjectsThe analysis was based on data from 2081 adults, 18–79 years of age, who participated in the Humboldt Study conducted in 2003. Doctor-diagnosed diabetes and family history of diabetes of biological parents and siblings were self-reported. Body weight and height were objectively measured. The interaction of family history and BMI on diabetes was assessed on an additive scale.ResultsThe prevalence of diabetes was 7·9 %, and BMI and history of diabetes were two important predictors. The adjusted prevalence ratios were 1·76 (95 % CI 1·37, 2·27) and 2·59 (95 % CI 2·05, 3·31) for those with a BMI of 25·0–29·9 kg/m2 and of at least 30 kg/m2, respectively, compared with a BMI of less than 25 kg/m2, and was 2·41 (95 % CI 2·08, 2·80) for those with a family history of diabetes v. those without. The data indicated an additive interaction of family history and BMI on diabetes.ConclusionsWhen exposed to both family history and overweight/obesity, individuals would have an increased risk that was greater than the sum of their single effects. Reduction of BMI would also reduce the risk of diabetes associated family history.

scholarly journals Prevalence of T2 Diabetes Mellitus (DM) Among the Rural People of Selected villages Of Bangladesh

2015 ◽  
Vol 4 (1) ◽  
pp. 22-29
Author(s):  
Md Yunus Ali ◽  
Maksuda Begum ◽  
Sultan Sobnam Dipu
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Middle Class ◽  
Demographic Data ◽  
Fasting Blood Glucose ◽  
Positive Association ◽  
Cross Sectional ◽  
Rural People ◽  
Family History Of Diabetes ◽  
History Of

Objectives: This cross-sectional study was conducted to find out the prevalence of type 2 diabetes and pre-diabetes ((PD) (Impaired fasting glucose-IFG, impaired glucose tolerance-IGT)) and to see the associations with risk factors. Methods: Two villages were randomly selected from rural area of Mymensingh district. 125 study subjects (≥30 years) were selected with systematic procedure but 118 samples were participated in the study. Below 30 years, diagnosed case of diabetes and urban people were excluded from study. Socio-demographic data were collected on a pre-tested interview schedule through face to face interview. DM, PD were interpreted by estimating fasting blood glucose level and 2 hour after 75 gm glucose load. Obesity was assigned by BMI. SPSS program (version 11.5) used for data analysis. Results: Mean age of participants was 46.68 with SD ± 12.698. Female participation (66.9%) was double compare to male, literacy rate was (64.4%) with female illiteracy of 29.67%. House wives (61.9%) were more than other professions. Middle class people were nearly 73%, Poor 14.4%, sedentary life style 11% and depressives 14.4% evident in study. A 20.3% people did laborious works. 17.8% had the family history of diabetes. Smokers (53.4%) were more than the non-smokers. Majority (89.0%) of rural people eat rice thrice a day. Normal BMI 61.0%, underweight 31.4% and 7.6% overweight observed.  Overall prevalence of T2 DM was 11.0% showing increase trend of diabetes compared to 8.6% estimated in 2000 and higher than several studies of home and abroad. Female showed higher prevalence (7.6%) compare to male (P>0.05). The overall prevalence of PD was 16.1% evident in this study. The prevalence of IFG and IGT were 8.5% and 7.6% respectively. Female showed higher prevalence of IFG (5.1%) and IGT (5.9%) than male (P>0.05). House wives showed higher prevalence (5.6%) of DM compare to other professions (P>0.05). Illiterates showed more PD (10.3%) and less DM (1.7%) but literates showed more (9.3%) DM (P >0.05). DM (6.7%) and PD (11.8%) more were among the middle class (P=0.018). A high prevalence of PD (13.6%) and DM (9.3%) noticed among non-sedentary lifestyle (P >0.05). Smoker showed higher DM (8.5%) and PD (11.8%). (P-0.071). Prevalence of PD and DM were high among the people with physically less active (P =0.795). Depressives showed more prevalence of DM (8.5%) and PD (13.5%), (P=0.345). increased frequency of rice eating (P=0.004), people with normal BMI (P=0.081) and family history of DM (P=0.000) showed positive association with diabetes mellitus. CBMJ 2015 January: Vol. 04 No. 01 P: 22-29

scholarly journals Prevalence and commonest predictors of gestational diabetes mellitus: a cross-sectional study

2019 ◽  
Vol 6 (1) ◽  
pp. 96
Author(s):  
Saranya Nagalingam ◽  
Vaishnavi Murugaraj
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Gestational Diabetes ◽  
Cross Sectional Study ◽  
Health Centers ◽  
Sectional Study ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Rural And Urban ◽  
History Of

Background: Babies born to mothers with GDM are at increased risk of complications, primarily growth abnormalities and chemical imbalances such as hypoglycemia, GDM is a reversible condition and women who have adequate control of glucose level scan effectively decrease the associated risks and give birth to healthy babies. The objective was to estimate the prevalence and the predictors of gestational diabetes mellitus.Methods: This study was conducted as a cross sectional study among the antenatal mothers at the outpatient department of the rural and urban health centers of the KG hospital and PG institute and its affiliated centers in Coimbatore. The study period was one year and during which 150 antenatal mothers participated in the study.Results: The prevalence of GDM was 76 (9%) and 74 (11%) in rural and urban health centers respectively. The maximum number of GDM Mothers to be 26-30years of age with a peak indicating 42% and 39% of GDM mothers were found to be in primigravida, 48% of GDM mothers were primipara. About 65% of GDM pre-pregnant mothers were overweight according to BMI, 53% of GDM mothers had positive family history of DM. Majority of the study population 100 (67%) had HBA1C less than 6% and the remaining 50 (33%) had more than 6% value. The variables like age, gravida, parity, family history of diabetes, pre-pregnant BMI, history of PCOS, history of hypertension, history of hypothyroidism was compared with the glycaemic status (HBA1C values) and it was found to be statistically significant at P<0.05.Conclusions: The commonest risk factors which increases the incidence of GDM were family history of diabetes mellitus, overweight pre-pregnant BMI, history of PCOS, hypothyroidism, increasing gravidity and parity respectively.

scholarly journals Risk Factors for Fracture in Diabetes: The Canadian Multicentre Osteoporosis Study

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Lisa-Ann Fraser ◽  
Alexandra Papaioannou ◽  
Jonathan D. Adachi ◽  
Jinhui Ma ◽  
Lehana Thabane
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Family History ◽  
Female Gender ◽  
Diabetic Patients ◽  
Mineral Density ◽  
Cross Sectional ◽  
Increased Risk ◽  
Traumatic Fracture ◽  
History Of

Objective. Individuals with diabetes have been found to be at increased risk of nontraumatic fracture. However, within the diabetic population, how to distinguish who is at the highest risk and warranting therapy has remained elusive. Design. Cross-sectional analysis of a national population-based cohort study. Patients. Men and women over the age of 50 with diabetes from across Canada. Measurements. Logistic regression analysis to identify diabetes specific factors associated with a history of one or more non-traumatic fractures. Results. Six hundred and six individuals with diabetes with a mean age of 69 years were examined. Thirty percent had a history of non-traumatic fracture. Macrovascular diseases in the form of stroke or TIA, as well as hypertension, were found to be independently associated with fragility fracture. Other, more traditional, clinical risk factors were also associated with fracture, including increased age, female gender, rheumatoid arthritis, family history of osteoporosis, and decreased bone mineral density. Conclusions. In this cohort of Canadians with diabetes, those with rheumatoid arthritis, a family history of osteoporosis, female gender, increased age, decreased BMD, cerebrovascular disease, or hypertension were more likely to have had a non-traumatic fracture. These risk factors may be important to clinicians when identifying which of their diabetic patients are at highest risk of fracture and in need of preventative therapies.

scholarly journals Prevalence of postpartum thyroiditis in women with gestational diabetes mellitus in Ardabil: North West of Iran

2016 ◽  
Vol 2 (6) ◽  
pp. 116
Author(s):  
Manouchehr Iranparvar-Alamdari ◽  
Hosein Ghorbani Behrooz ◽  
Mostafa Alidousti
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Thyroid Stimulating Hormone ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Postpartum Thyroiditis ◽  
Pregnancy And Postpartum ◽  
History Of

<p class="abstract"><strong>Background:</strong> Gestational diabetes is the most common metabolic disorder during pregnancy and postpartum thyroiditis is a destructive thyroiditis that can cause serious complications for the mother and her child. The purpose of this study was to determine the prevalence of postpartum thyroiditis in women with gestational diabetes.</p><p class="abstract"><strong>Methods:</strong> In this cross-sectional study, 86 cases satisfy inclusion criteria and gestational diabetes mellitus (GDM) and were evaluated for postpartum thyroiditis with thyroid stimulating hormone (TSH), T4, anti-TPO, T3RU tests. The groups with and without thyroiditis were compared and data was analyzed by statistical methods.</p><p class="abstract"><strong>Results:</strong> There were 17 patients (19.8%) with postpartum thyroiditis, of whom 4 patients (23.5%) had hyperthyroidism, 9 patients (52.9%) were in the age group of 21 to 30 years, and 9 patients (52.9%) had a family history of diabetes.  Five patients (29.4%) with high anti-TPO level (P=0.022) and mean TSH and anti-TPO respectively, 2.8 (4.8) and 17.2 (35.9).</p><p><strong>Conclusions:</strong> The results showed that higher level of anti TPO titer and family history of diabetes can be associated with a higher rate of postpartum thyroiditis, so it is recommended that postpartum thyroiditis to be examined in women with gestational diabetes who have these mentioned items.</p>

scholarly journals Risk factors for type 2 diabetes mellitus: An urban perspective

2019 ◽  
Vol 71 ◽  
pp. 16-21
Author(s):  
Reshma Patil ◽  
Jayashree Gothankar
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Family History ◽  
Waist Circumference ◽  
Cross Sectional Study ◽  
Lifestyle Changes ◽  
Chi Square ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
History Of

Background: Diabetes mellitus is rising to an alarming epidemic level; hence, strategies formulated based on the risk factors can be helpful to curb the rising trend of the same. Objective: The objective of the study was to assess the prevalence of diagnosed cases of diabetes mellitus and correlate it with various risk factors and sociodemographic variables. Methods: A cross-sectional study was carried out in randomly selected wards under the field practice area of Urban Health Training Center of Private Medical College, Pune, Maharashtra. A total of 425 subjects aged 20 years and above residing in the study area were screened for diabetes mellitus. Risk factors such as age, waist circumference, waist-to-hip ratio (WHR), family history of diabetes, and physical activities were recorded. The statistical analysis of the data was performed using Chi-square test. Results: The prevalence of diagnosed cases of diabetes mellitus found in this study was 9.88%. There was a significant increase in the prevalence of diabetes as age increases (age 20–34 years: 1.66%, 35–49 years: 7.53%, ≥50 years: 15.66%, and P < 0.05). Furthermore, male gender, obesity, waist circumference, WHR, and diabetes mellitus were found to be statistically significant. Conclusions: Risk factors such as rising age, family history of diabetes mellitus, lack of physical activity, and central obesity were the most common factors found in diagnosed cases of diabetes mellitus. Therefore, lifestyle changes and awareness regarding risk factors is needed to make control over the diabetes.

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