scholarly journals Congenital anomalies in Santa Catarina: case distribution and trends in 2010–2018

2022 ◽  
Vol 40 ◽  
Author(s):  
Bruna Muraro Vanassi ◽  
Gabriel Cremona Parma ◽  
Vivyane Santiago Magalhaes ◽  
Augusto César Cardoso dos Santos ◽  
Betine Pinto Moehlecke Iser

Abstract Objective: To evaluate the distribution of cases of congenital anomalies in the state of Santa Catarina by health macro-region, to determine the frequency according to maternal and neonatal variables, to estimate the related mortality, and the trends in the period 2010–2018. Methods: An ecological time-series study with secondary data on congenital anomalies and the sociodemographic and health variables of mothers and newborns living in Santa Catarina, from 2010 to 2018. For temporal trend analysis, generalized linear regression was performed using the Prais-Winsten method with robust variance. Results: The average prevalence of congenital anomalies in the period was 8.9 cases per 1,000 live births, being 9.4 cases by 1,000 live births in 2010 and, in 2018, 8.2/1,000. The trend remained stable in the analyzed period. The major malformations were musculoskeletal, hip, and foot malformations, with a proportion ≥30%. There was a higher prevalence of congenital anomalies in low birthweight, preterm, male livebirths with Apgar≤7, born by cesarean section, mothers of older age (≥40 years), and less educated (less than eight years of study). Infant mortality due to congenital malformations was 2.6 deaths/1,000 live births, representing about 25.8% of the total infant deaths in the period. Conclusions: The frequency of congenital anomalies and the mortality with anomalies was stable in the studied period in Santa Catarina. The presence of anomalies was associated with low birth weight, prematurity, and low Apgar score. The highest proportion of congenital anomalies was in the musculoskeletal system.

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e023420 ◽  
Author(s):  
Márcio Bezerra Santos ◽  
Allan Dantas dos Santos ◽  
Aline Silva Barreto ◽  
Mariana do Rosário Souza ◽  
Marco Aurélio de Oliveira Goes ◽  
...  

ObjectiveThis study aimed to analyse the clinical and epidemiological indicators, temporal trends and the spatial distribution of leprosy in patients under 15 years old in an endemic area of Northeast Brazil.DesignRegional surveillance study of all reported cases.SettingState of Sergipe, endemic area of Northeast Brazil.MethodsAn ecological and time series study was conducted, based on secondary data reported by the Brazilian Information System on Notifiable Diseases for leprosy cases diagnosed in Sergipe state (2002–2015). The analysis of temporal trends was performed using the Joinpoint Regression Programme through Poisson regression. We performed spatial analysis by Kernel estimator and Moran index.ResultsThe incidence rate was reduced from 6.29 to 3.78 cases per 100 000 inhabitants in 2002 and 2015, respectively. However, Sergipe was still classified as highly endemicity in 2015. The mean number of household contacts (HHC) examined was significantly lower than those registered. Clinical data indicated that 21.4% of the patients developed leprosy reactions, and 31.3% presented with some physical disability in the multibacillary groups. Patients diagnosed by examination within the HHC presented better indicators, such as lower percentage of leprosy reaction and physical disability. Spatial analysis showed the most risk areas distributed on the northeast and cities around the capital, Aracaju.ConclusionThe data indicate that there is a persistence of activeMyobacterium lepraetransmission and a delay in disease detection, following a pattern of high endemicity in many municipalities. The early detection by HHC examination is important to stop transmission and also to detect the cases in a less severe state.


2019 ◽  
Vol 17 (1) ◽  
pp. 55
Author(s):  
Lendi Ageng Kurnia ◽  
Deden Dinar Iskandar

In maintaining the stability of national rice availability, 3 supporting aspects are needed, namely increasing domestic rice production, procuring government rice reserves through Bulog and importing rice. The purpose of this study is 1) to find out the factors that influence the availability of national rice, 2) to find out the factors that influence food independence, especially rice. The data used is secondary data sourced from BPS, FAO statistics and IRRI statistics. The research design used in this study is a time series study from 1970-2016. The model used in the study is Least Square (LS). The results of the analysis show partially the availability of national rice influenced by domestic rice production, government rice reserves and rice imports. While the ability of domestic rice production in supplying the availability of national rice, which is represented in the substance of food independence, is influenced by productivity, rice supply stability, price gap of rice / rice and farmers' welfare. However, it is not influenced by the application of appropriate technology (in this case the use of subsidized fertilizer). The conclusion of this study is that the availability of national rice is not only supplied from within the country but must still be supported by the procurement of imported rice. In increasing food independence, productivity must be increased, ensuring that government rice reserves are always available, monitoring the development of rice / rice prices are always stable, and paying attention to the welfare of farmers as the main actors in rice trading. Whereas the government's policy of providing subsidized fertilizers needs to be refined and monitored in the field because so far only serves as a complement in the provision of rice to the community.


2008 ◽  
Vol 7 (1) ◽  
Author(s):  
Ai Ishigami ◽  
Shakoor Hajat ◽  
R Sari Kovats ◽  
Luigi Bisanti ◽  
Magda Rognoni ◽  
...  

2019 ◽  
Vol 1 (2) ◽  
pp. 171-188
Author(s):  
Eduardo Ottobelli Chielle ◽  
Fagner Genz ◽  
Abel Petter

Suicide has been a subject of increasing concern and the toxicological and blood alcohol investigate in these victims is little studied. This study investigated the toxicological and blood alcohol profile of suicide victims in 27 municipalities in the extreme west of Santa Catarina. Aggregate time series study, with a survey of epidemiological data and analysis of expert reports by the Medical Legal Institute of all fatal victims of suicide, registered in the period between 2012 to 2016. Results: Males, aged 50-59 years, were the main victims and the hanging the main suicide method. The months of February and November, Sundays and the time of 08:00 to 11:59 were the moments of greater occurrences. Elevated levels of alcohol were observed in 23.97% of the victims and the main drugs found were benzodiazepines and tricyclic antidepressants. The results obtained in this study reinforce the concern regarding cases of suicide and an association between alcohol/drug use and suicidal practices. The data provide subsidies for elaboration and implementation of preventive actions. Professionals should be alert to signs of suicide, so that specialized help becomes a possible option, and is instrumental in reducing the number of suicides.


PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256169
Author(s):  
Ketyllem Tayanne da Silva Costa ◽  
Thiffany Nayara Bento de Morais ◽  
Dayane Caroliny Pereira Justino ◽  
Fábia Barbosa de Andrade

The World Health Organization declared, at the end of 2019, a pandemic caused by SARS-CoV-2, a virus that causes Coronavirus Disease—COVID-19. Currently, Brazil has become the epicenter of the disease, registering approximately 345 thousand deaths. Thus, the study has scientific relevance in health surveillance as it identifies, quantifies and monitors the main behavioral patterns of the mortality rate due to COVID-19, in Brazil and in their respective regions. In this context, the study aims to assess the epidemiological behavior of mortality due to COVID-19 in Brazil: a time series study, referring to the year 2020. This is an ecological time series study, constructed using secondary data. The research was carried out in Brazil, having COVID-19 deaths as the dependent variable that occurred between the 12th and 53rd Epidemiological Week of 2020. The independent variable will be the epidemiological weeks. The data on deaths by COVID-19 were extracted in February 2021, on the Civil Registry Transparency Portal. The cleaning of the database and the information were treated in the Microsoft Excel® Software and, for statistical analysis, the JoinPoint software, version 4.7.0.0 was used. It was observed that Brazil presents an upward curve between the 12th and 19th SE, when it reaches saturation at the peak of mortality, which remains until the 35th SE and, subsequently, a downward curve was identified until the 47th SE, period in the which curve turns back up.


2019 ◽  
Author(s):  
Apub Marhen ◽  
Irdha Yusra

This study aimed to prove the influence of inflation, interest rates certificates of Bank Indonesia, and exchange rate rupiah on composite stock price index (CSPI) in Indonesia Stock exchange. The period used in the study was three years from 2015 to 2017. The research design was causal associative and this was a time-series study using CSPI at Indonesia Stock Exchange. This data type is a documentary. Source data using secondary data. Analysis methods using classical assumption, multiple regression analysis, and t-test. The result there the influence of inflation is not influenced toward composite stock price index, interest rates of Indonesia Bank are negative significant toward composite stock price index, and there is not the influence of exchange rate rupiah toward composite stock price index


2014 ◽  
Vol 56 (2) ◽  
pp. 151-155 ◽  
Author(s):  
Chaiana Esmeraldino Mendes Marcon ◽  
Ione Jayce Ceola Schneider ◽  
Jefferson Traebert

Hepatitis B is a serious public health problem. The state of Santa Catarina presents areas of high endemicity. The aim of this study was to describe temporal trends in detection rates of hepatitis B in the period from 2002 to 2009 in Santa Catarina and in its regions. A time series study was carried out. Crude rates were calculated and standardized by age using the direct method. Annual variation percentages were estimated by Joinpoint regression. There were two distinct and significant trends in Santa Catarina. From 2002 to 2006 a significant increase of 5.9% per year was observed. From 2006, there was a significant decrease of 6.4% per year. In this same period the southern and far-western regions had significant increases of 15.9% and 4.6% and significant decreases of 7.5% and 4.8%, respectively. Greater Florianópolis and Northeast also showed significant increases until 2006, of 15.4% and 17.4%, respectively. In the following period, non-significant decreases of 5.8% and 9.8% respectively were observed. Foz do Rio Itajaí and Planalto Serrano showed non-significant increases up to half of the studied period of 21.1% and 12.0%, respectively and after, significant decreases of 21.5% and 18.0%, respectively. Vale do Itajaí showed a significant decrease of 9.7%; Planalto Norte showed a non-significant decrease of 0.6% and Midwest a non-significant increase of 2.7% per year, in the period from 2002 to 2009.


Author(s):  
Ania Zylbersztejn ◽  
Ruth Gilbert ◽  
Anders Hjern ◽  
Pia Hardelid

IntroductionChild mortality is nearly twice as high in England as in Sweden. A comparison of mortality from potentially preventable causes could inform health system responses. This study focused on respiratory tract infection (RTI)-related deaths, amenable to healthcare interventions, and sudden unexpected deaths in infancy (SUDI), amenable to public health interventions. Objectives and ApproachWe developed nationally-representative birth cohorts of singleton live births in 2003-2012 using a hospital admissions database in England and the Medical Birth Register in Sweden. Children were followed-up from 31st day of life until their fifth birthday via linkage to hospital admission and mortality records. We compared child mortality using Cox proportional hazards models to estimate hazard ratios (HR) for England versus Sweden for RTI-related mortality at 31-364 days and 1-4 years, and for SUDI mortality at 31-364 days. Models were adjusted for birth characteristics (gestational age, birthweight, sex, congenital anomalies), and socio-economic factors (maternal age and socio-economic status). ResultsOf 3,928,483 children in England, there were 807 RTI-related deaths at 31-364 days (17% of all deaths in the age range), 691 deaths at 1-4 years (31%), and 1,166 SUDIs (24%) in England. Corresponding figures for 1,012,682 children in Sweden were 136 (18%), 118 (25%) and 189 (24%). Unadjusted HRs for RTI-related deaths in England versus Sweden were 1.50 (95% confidence interval: 1.25-1.80) at 31-364 days. Adjustment for birth characteristics reduced the HR to 1.16 (0.97-1.39), and for socio-economic factors to 1.11 (0.92-1.33). Corresponding figures for RTI-related mortality at 1-4 years were 1.58 (1.30-1.92), 1.32 (1.09-1.61) and 1.30 (1.07-1.59), respectively. Unadjusted HRs for SUDIs reduced from 1.59 (1.36-1.85) to 1.40 (1.20-1.63) after adjusting for birth characteristics, and to 1.19 (1.02-1.39) after adjusting for socio-economic factors. Conclusion/ImplicationsHigher prevalence of adverse birth characteristics (such as prematurity, low birthweight, congenital anomalies) contributed to increased risks of RTI-related and SUDI mortality in England relative to Sweden. Therefore, preventive strategies should focus on maternal health and socio-economic circumstances before and during pregnancy to reduce RTI-related and SUDI mortality in England.


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