scholarly journals Candida spp. isolated from inpatients, the environment, and health practitioners in the pediatric unit at the Universitary Hospital of the Jundiaí Medical College, state of São Paulo, Brazil

2012 ◽  
Vol 45 (2) ◽  
pp. 225-231 ◽  
Author(s):  
Lucas Ruiz Storti ◽  
Giuliano Pasquale ◽  
Rogério Scomparim ◽  
Ana Lúcia Galastri ◽  
Flávio Alterthum ◽  
...  

INTRODUCTION: This study aimed to isolate and identify Candida spp. from the environment, health practitioners, and patients with the presumptive diagnosis of candidiasis in the Pediatric Unit at the Universitary Hospital of the Jundiaí Medical College, to verify the production of enzymes regarded as virulence factors, and to determine how susceptible the isolated samples from patients with candidiasis are to antifungal agents. METHODS: Between March and November of 2008 a total of 283 samples were taken randomly from the environment and from the hands of health staff, and samples of all the suspected cases of Candida spp. hospital-acquired infection were collected and selected by the Infection Control Committee. The material was processed and the yeast genus Candida was isolated and identified by physiological, microscopic, and macroscopic attributes. RESULTS: The incidence of Candida spp. in the environment and employees was 19.2%. The most frequent species were C. parapsilosis and C. tropicalis among the workers, C. guilliermondii and C. tropicalis in the air, C. lusitanae on the contact surfaces, and C. tropicalis and C. guilliermondii in the climate control equipment. The college hospital had 320 admissions, of which 13 (4%) presented Candida spp. infections; three of them died, two being victims of a C. tropicalis infection and the remaining one of C. albicans. All the Candida spp. in the isolates evidenced sensitivity to amphotericin B, nystatin, and fluconazole. CONCLUSIONS: The increase in the rate of hospital-acquired infections caused by Candida spp. indicates the need to take larger measures regarding recurrent control of the environment.

2012 ◽  
Vol 6 (2) ◽  
pp. 7-10
Author(s):  
Mohammad Murshed ◽  
Sabeena Shahnaz ◽  
Md. Abdul Malek

Isolation and identification of post operative hospital acquired infection was carried out from July 2008 to December 2008 in Holy Family Red Crescent Medical College Hospital (private hospital). The major pathogen of wound infection was E. coli. A total; of 120 samples were collected from the surrounding environment of post operative room like floor, bed sheets, instruments, dressing materials, catheter, nasogastric and endotracheal tube. E. coli (40%) was the predominant organism followed by S. aureus (24%). DNA fingerprinting analysis using pulsed field gel electreopheresis of XbaI restriction digested genomic DNA showed that clonal relatedness between the two clinical nd environmental isolates were 100%.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19369 Bangladesh J Med Microbiol 2012; 06(02): 7-10


2013 ◽  
Vol 2 (2) ◽  
pp. 77-79
Author(s):  
Shubhada Avachat ◽  
Deepak Phalke ◽  
Mrinal Zambare ◽  
Vaishali Phalke

Hospital-acquired infection (HAI) in healthcare settings is the most frequent adverse event in healthcare delivery worldwide. Hundreds of millions of patients are affected by HAI worldwide each year, leading to significant patient mortality rates and financial losses for health systems. We evaluated the impact of a sensitization workshop on knowledge and awareness of HAI among nurses in a medical college hospital in rural area of Ahmednagar district, India from March 2010 to August 2010. One hundred staff nurses, who had more than one year of experience, had attended the workshops on HAI. Pre- and post-test data was collected by a questionnaire. A significant increase in number of nurses having knowledge regarding commonly occurring HAI and routes of transmission , barrier nursing and hygienic hand washing techniques, hospital waste management (its importance and color coding), and the im-portance of an infection control team was observed after the workshop. Education and training of healthcare workers about standard infection control can reduce the extent of risks of HAI. Nurses have a critical role to play in preven-tion measures and infection control and they should have the opportunity for continuous professional development. DOI: http://dx.doi.org/10.3329/seajph.v2i2.15960 South East Asia J Public Health | Jul-Dec 2012 | Vol 2 Issue 2 | 77-79


2020 ◽  
Vol 3 (2) ◽  
pp. 141-146
Author(s):  
Sarkar T

Candida spp. colonizes the human host and coexists with members of the human microbiome. Candida glabrata are aggressive pathogens, have many virulence factors that lead to serious recurrent candidiasis. Their ability to form a complex biofilm, inability to form hyphae, and inability to secrete hydrolase lead to antifungal resistance. Candidemia is the fourth most common bloodstream infection [1]. Candidemia remains a major source of mortality and morbidity. Mortality among patients with invasive candidiasis is as high as 40%, even when patients receive antifungal therapy [2]. More than 90% of invasive diseases are caused by the 5 most common Candida spp. C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, and C. krusei [3]. The distribution of Candida species has been changing over the last decade, with a decrease in the proportion of C. albicans and an increase in C. glabrata and C. parapsilosis. More than 50% of bloodstream infections are caused by non-albicans Candida [2,4]. The largest proportional increase in the USA is in C. glabrata, which accounts for one third or more of all candidemia isolates [5-7]. C.glabrata are associated with high mortality. Candida glabrata develop acquired resistance following exposure to antifungal agents [8]. 50% of C. glabrata are resistant to fluconazole [9,10]. Furthermore, 9% of C. glabrata that are resistant to fluconazole are also resistant to the echinocandins [8,11].


1970 ◽  
Vol 21 (2) ◽  
pp. 121-125 ◽  
Author(s):  
M Azizul Haque ◽  
Q Tarikul Islam ◽  
MA Razzak ◽  
MA Faiz ◽  
M Iqbal Bari

The study was carried out in Medicine and Pediatrics Department of Rajshahi Medical College Hospital, and Natore Sadar Hospital, both are located in the northern territory of Bangladesh. Period of study ranged from admission of patients till discharge. On 8th June 2008, 83 patients of Singra Upazilla Natore were admitted in Rajshahi Medical College Hospital and Natore Sadar Hospital with the history of consumption of Puffer fish. A presumptive diagnosis of Puffer fish poisoning was made on the basis of classical clinical presentations followed by Puffer fish ingestion. Blood and urine samples from 38 patients were sent to Frankfurt, Germany for toxicological analysis. The cases were clinically reviewed periodically and routine investigations were done. Report of the toxicological study confirmed the diagnosis of tetrodotoxin poisoning. Important neurological symptoms observed were peri-oral paresthesia (71), tingling over entire body (50), dizziness (35), headache (20). Muscular paralysis of the limbs was noted in 13 patients, of which 7 patients developed respiratory involvement. All the patients who developed respiratory involvement died. Early diagnosis and supportive management could ensure a safe and favorable outcome. Management of respiratory failure by ventilator support can be life saving. doi: 10.3329/taj.v21i2.3790 TAJ 2008; 21(2): 121-125


2020 ◽  
Vol 17 (1) ◽  
pp. 53-55
Author(s):  
Md Abdul Awal ◽  
Shahara Haque ◽  
Mst Nazmun Nahar ◽  
Husne Ara ◽  
Farhana Kamal

Prune belly Syndrome (PBS), a rare congenital anomaly of uncertain aetiologies has been seldom reported among Bangladeshis. Prune belly syndrome is a birth defect that involve three main problems like poor development of the abdominal musclescausing the skin of the belly area to wrinkle like a prune, undescended testicles and urinary tract problems. We report a case of 15 days old term male neonate with PBS. The baby named Shumon was admitted in Dhaka Medical College Hospital with complaint of lax abdominal wall, absence of both testes since birth. He was born by NVD and consulted with a local doctor who commented that the baby was not normal and referred to Dhaka Medical College Hospital for better management. On physical examination the baby weighted 2.7Kg and full length was 40 cm. He was mildly pale, his respiratory rate was 32 cycles per minute with normal breath sounds. Heart rate was 134 beats per minute. His abdomen was flabby with a wrinkled appearance and there were visible peristalses with palpable kidneys & bilateral undescended testes. His B.P was within normal range and cardiac examination was normal clinically and echocardiographically. USG of abdomen showed bilateral gross hydronephrosis with mega ureter. Micturating cystography showed grade-IV vesico-ureteric reflux bilaterally with no urethral obstruction. Serum creatinine concertration was 80 μmol/L, Serum Sodium was 130 mmol/L and Serum Potassium was 5.8 mmol/L. The presumptive diagnosis was Prune Belly Syndrome. Bangladesh Journal of Urology, Vol. 16, No. 1, Jan 2014 p.53-55


2018 ◽  
Vol 17 (1) ◽  
pp. 42-45
Author(s):  
Raushan Akter ◽  
Mahtab Uddin Hassan ◽  
Rajat Sankar Roy Biswas

Background: Hospital acquired urinary tract infection among the hospitalized catheterized patient due to different indications are a common morbility. The objective of study to see the prevalence hospital acquired urinary tract infection among the patients of indwelling catheter admitted in the department Medicine of Chittagong Medical College Hospital. Methods: It was a hospital based obsevational study conducted on purposively selected (Non-probability) hospitalized patients who got indwelling catheter had admitted into the Medicine ward, Chittagong Medical College Hospital from 1st January 2013 to 30th June 2013. Total 50 patients were selected. Urine was analyzed for growth of organism and sensitivity was also done in case where growth was positive. Data was analyzed by statistical method with the software SPSS-20. Results: Results showed that 15 (30%) developed bacteriuria or urinary tract infection with catheter. Development of bacteriuria was not affected by sex, age. People who introduce the catheter has some influence with the occurrence of UTI. E.coli, Klebsella, Proteas and Pseudomonas aeroginosa were the most common bacteria isolated. Imepenam was found the most sensitive antibiotic. Conclusion: Catheter play an important risk for occurrence of UTI. So it should be avoided if possible. Chatt Maa Shi Hosp Med Coll J; Vol.17 (1); Jan 2018; Page 42-45


2020 ◽  
Vol 28 (1) ◽  
pp. 49-53
Author(s):  
Debesh Chandra Talukder ◽  
Satinath Chandra Sarker ◽  
Syed Ali Ahasan ◽  
Muhammad Mozammal Haque ◽  
Mostafa Kamal Arefin ◽  
...  

Background: To study the incidence, clinical presentation and to observe comparison of different sinonasal masses. Materials and Methods: This Prospective study was carried out from January 2017 to December 2018. Data were collected from 100 patients presented with sinonasal masses. This study is based on history, clinical, radiological, laboratory and histopathological examination. Results: During the study period, 100 patients presented with sinonasal masses (male 60, female 40; age group 8-70 years).Nasal polyploid masses were non-neoplastic in 70 (70%) subjects, and neoplastic in 30 (30%) cases. Nasal obstruction was the most common (95%) presenting complaint, followed by rhinorrhoea (48%), hyposmia (30%), intermittent epistaxis (17%), headache (15%), facial swelling (10%) and eye-related symptoms (10%). The most common site of origin of polyploid masses was the middle meatus (54%) followed by the lateral wall of the nasal cavity (15%) and superior meatus (11%). unilateral nasal masses was present in 49% patients, while the remaining patients had bilateral nasal masses. Allergic (60%) and inflammatory (28.5%) polyps were the most common non-neoplastic mass, inverted papilloma (41.17%) and haemangioma (35.29%) were most common benign neoplastic mass; 92.3% of all malignant masses were squamous cell carcinoma. Surgery was the major mode of treatment. it included Caldwell-luc operation (7%), polypectomy (10%), excision of mass (25.0%) and functional endoscopic sinus surgery (44%). Malignancies were treated with radiotherapy or Surgery followed by radiotherapy or Chemoradiotherapy. Conclusions: The masses in nasal cavity, paranasal sinuses, and nasopharynx encompass a wide spectrum of common and rare diseases and are very common lesions encountered in clinical practice. Endoscopic examination and advanced imaging technique help to reach a presumptive diagnosis but histopathological examination remains the mainstay of final definitive diagnosis. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 49-53


2009 ◽  
Vol 25 (1) ◽  
pp. 76 ◽  
Author(s):  
UmeshS Kamat ◽  
Agnelo Fereirra ◽  
Dilip Amonkar ◽  
DilipD Motghare ◽  
ManojS Kulkarni

Author(s):  
Monika Kushwaha ◽  
Sanjeev Narang

Background: This study is cross-sectional, observational and comparative study, at Index Medical College, Hospital & Research Centre, Indore, Madhya Pradesh from July 2017 to July 2019 with sample size 100 placentae. Method: The placenta received was evaluated blinded of maternal pregnancy outcome. The pattern of morphology was evaluated both qualitatively (type of lesion) and quantitatively (number of lesions). Result: In Present study 79% of the deliveries were term deliveries and 21% were preterm deliveries. On placental macroscopy, placenta weight was significantly low among the neonates of preterm deliveries (370.00±60.49) as compared to term deliveries (440.89±55.22). Preterm placenta had higher number of abnormal placental lesion compared to term pregnancies. Conclusion: The uteroplacental insufficiency defined as placental infarct, fibrosis of chorionic villi, thickening of blood vessels, and poor vascularity of chorionic villi. Placental histopathological lesions are strongly associated with maternal under perfusion and uteroplacental insufficiency. These are the reasons for preterm birth. Thus, knowledge of the etiological factor can be use to reduce maternal and neonatal morbidity and mortility. Keywords: Placenta, Term & Preterm.


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