scholarly journals Methods used in the 1982, 1993, and 2004 birth cohort studies from Pelotas, Rio Grande do Sul State, Brazil, and a description of the socioeconomic conditions of participants' families

2008 ◽  
Vol 24 (suppl 3) ◽  
pp. s371-s380 ◽  
Author(s):  
Aluísio J. D. Barros ◽  
Iná S. Santos ◽  
Alicia Matijasevich ◽  
Cora L. Araújo ◽  
Denise P. Gigante ◽  
...  

Three birth cohorts are currently being followed in Pelotas, Southern Brazil, in order to assess changes in birth conditions, growth, development, morbidity, and infant mortality, as well as the influence of pre- and perinatal factors on the subsequent morbidity of participants in their adult lives. We provide a description of the methodology used for the cohort studies that began in 1982, 1993, and 2004 in Pelotas, and a description of the economic conditions of the families involved. For the three cohorts, similar strategies were used to recruit babies born to mothers living in the municipality's urban area. These included daily visits to maternity hospitals where births were identified, mothers interviewed, and newborns examined. Over this time frame, there has been a significant reduction in the number of births due to declining fertility rates amongst the target population. Salaries (measured as a multiple of the minimum wage) were stable across cohorts, but quality of life indicators - such as the availability of piped water, flushing toilets and refrigerators - showed clear improvements. Mothers' levels of education improved markedly. Important changes in the demographic profile of risk factors and health outcomes are being recorded by the Pelotas cohorts.

2020 ◽  
Vol 56 (5) ◽  
pp. 2000168
Author(s):  
Cristina Ardura-Garcia ◽  
Rebeca Mozun ◽  
Eva S.L. Pedersen ◽  
Maria Otth ◽  
Maria Christina Mallet ◽  
...  

The paediatric respiratory research community uses cohort studies extensively. However, the landscape of these studies and their quality of reporting has not been assessed.We performed a systematic review of publications on cohort studies reporting on paediatric lower respiratory problems published in 2018. We searched MEDLINE and Embase and extracted data on study and journal characteristics. We assessed the number of items of the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) checklist that a random sample (100 papers) reported. We analysed factors associated with the STROBE score and with the most poorly reported items, using Poisson and logistic regression.Of the 21 319 records identified, 369 full-text articles met our inclusion criteria. Most papers studied asthma aetiology through birth cohorts and were based in Europe or North America. The reporting quality was insufficient: 15% reported the 22 STROBE items; median (interquartile range) score 18 (16–21). The most poorly reported items were sources of bias, sample size, statistical methods, descriptive results and generalisability. None of the study or journal factors were associated with the STROBE score.We need a joint effort of editors, reviewers and authors to improve the reporting quality of paediatric cohort studies on respiratory problems.


2021 ◽  
Vol 7 (1) ◽  
pp. 15-26
Author(s):  
Ume Laila ◽  
Najma Sadiq ◽  
Tahir Mehmood ◽  
Khansa Almas

This study aims to asses the socioeconomic conditions of the beneficiaries who are associated with Pakistan Bait ul Mal and are receiving funds. The target population of this research were the beneficiaries affiliated with the Pakistan Baitul Mal regardless of the fat that whether they have received the programs and services in the given time frame or not. The quantitative data collected was on the bases of telephonic surveys which targeted a total of 155 beneficiaries. After a careful analysis of data, it was revealed that most of them agreed that these services have positively impacted on their socioeconomic conditions. The top three influencing factors in this study include the difficulty in application process, monthly household income and employment status. Briefly, this study has also provided some recommendations through which the scope and working of organization can be enhanced.


2019 ◽  
Vol 18 (4) ◽  
pp. 1844-1885
Author(s):  
Simen Markussen ◽  
Knut Røed

Abstract Based on complete population data, with the exact same definitions of family class background and economic outcomes for a large number of birth cohorts, we examine post-war trends in intergenera-tional economic mobility in Norway. Standard summary statistics indicate stable or mildly declining rank–rank mobility for sons and sharply declining mobility for daughters. The most conspicuous trend in the mobility patterns is that men and women born into the lowest parts of the parental earnings distribution have fallen behind in terms of own earnings rank, as well as a number of other quality-of-life indicators. A considerable part of this development can be explained by changes in the class distribution of educational attainment and in its rising influence on earnings rank. We argue that although the educational revolution has diminished the role of inherited ability, it has enlarged the influence of the family as provider of a social learning environment.


2018 ◽  
Vol 1 (2) ◽  
pp. 1
Author(s):  
Andi Asadul Islam

Neurosurgery is among the newest of surgical disciplines, appearing in its modern incarnation at the dawn of twentieth century with the work of Harvey Cushing and contemporaries. Neurosurgical ethics involves challenges of manipulating anatomical locus of human identity and concerns of surgeons and patients who find themselves bound together in that venture.In recent years, neurosurgery ethics has taken on greater relevance as changes in society and technology have brought novel questions into sharp focus. Change of expanded armamentarium of techniques for interfacing with the human brain and spine— demand that we use philosophical reasoning to assess merits of technical innovations.Bioethics can be defined as systematic study of moral challenges in medicine, including moral vision, decisions, conduct, and policies related to medicine. Every surgeon should still take the Hippocratic Oath seriously and consider it a basic guide to follow good medical ethics in medical practice. It is simple and embodies three of the four modern bioethics principles – Respecting autonomy, beneficence, nonmaleficence, and justice.Spinal cord injury (SCI) is a devastating condition often affecting young and healthy individuals around the world. Currently, scientists are pressured on many fronts to develop an all-encompassing “cure” for paralysis. While scientific understanding of central nervous system (CNS) regeneration has advanced greatly in the past years, there are still many unknowns with regard to inducing successful regeneration. A more realistic approach is required if we are interested in improving the quality of life of a large proportion of the paralyzed population in a more expedient time frame.


BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e042325
Author(s):  
Qirong Chen ◽  
Chongmei Huang ◽  
Aimee R Castro ◽  
Siyuan Tang

IntroductionNursing research competence of nursing personnel has received much attention in recent years, as nursing has developed as both an independent academic discipline and an evidence-based practiing profession. Instruments for appraising nursing research competence are important, as they can be used to assess nursing research competence of the target population, showing changes of this variable over time and measuring the effectiveness of interventions for improving nursing research competence. There is a need to map the current state of the science of the instruments for nursing research competence, and to identify well validated and reliable instruments. This paper describes a protocol for a scoping review to identify, evaluate, compare and summarise the instruments designed to measure nursing research competence.Methods and analysisThe scoping review will be conducted following Arksey and O’Malley’s methodological framework and Levac et al’s additional recommendations for applying this framework. The scoping review will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist. The protocol is registered through the Open Science Framework (https://osf.io/ksh43/). Eight English databases and two Chinese databases will be searched between 1 December 2020 and 31 December 2020 to retrieve manuscripts which include instrument(s) of nursing research competence. The literature screening and data extraction will be conducted by two researchers, independently. A third researcher will be involved when consensus is needed. The COnsensus-based Standards for the selection of health Measurement INstruments methodology will be used to evaluate the methodological quality of the included studies on measurement properties of the instruments, as well as the quality of all the instruments identified.Ethics and disseminationEthical approval is not needed. We will disseminate the findings through a conference focusing on nursing research competence and publication of the results in a peer-reviewed journal.


2020 ◽  
pp. 1-13
Author(s):  
Mariane da Silva Dias ◽  
Alicia Matijasevich ◽  
Aluísio JD Barros ◽  
Ana Maria B. Menezes ◽  
Bruna Celestino Schneider ◽  
...  

Abstract Objective: We aimed at evaluating the association of maternal pre-pregnancy nutritional status with offspring anthropometry and body composition. We also evaluated whether these associations were modified by gender, diet and physical activity and mediated by birth weight. Design: Birth cohort study. Setting: Waist circumference was measured with an inextensible tape, and fat and lean mass were measured using dual-energy X-ray absorptiometry. Multiple linear regression was used to adjust for possible confounders and allele score of BMI. We carried out mediation analysis using G-formula. Participants: In 1982, 1993 and 2004, all maternity hospitals in Pelotas (South Brazil) were visited daily and all live births whose families lived in the urban area of the city were evaluated. These subjects have been followed up at different ages. Results: Offspring of obese mothers had on average higher BMI, waist circumference and fat mass index than those of normal weight mothers, and these differences were higher among daughters. The magnitudes of the association were similar in the cohorts, except for height, where the association pattern was not clear. In the 1982 cohort, further adjustment for a BMI allele score had no material influence on the magnitude of the associations. Mediation analyses showed that birth weight captured part of this association. Conclusions: Our findings suggest that maternal pre-pregnancy nutritional status is positively associated with offspring BMI and adiposity in offspring. And this association is higher among daughters whose mother was overweight or obese and, birth weight explains part of this association.


2007 ◽  
Vol 12 (1) ◽  
pp. 37-62 ◽  
Author(s):  
Paul Lambert ◽  
Kenneth Prandy ◽  
Wendy Bottero

This paper discusses long term trends in patterns of intergenerational social mobility in Britain. We argue that there is convincing empirical evidence of a small but steady linear trend towards increasing social mobility throughout the period 1800-2004. Our conclusions are based upon the construction and analysis of an extended micro-social dataset, which combines records from an historical genealogical study, with responses from 31 sample surveys conducted over the period 1963-2004. There has been much previous study of trends in social mobility, and little consensus on their nature. We argue that this dissension partly results from the very slow pace of change in mobility rates, which makes the time-frame of any comparison crucial, and raises important methodological questions about how long-term change in mobility is best measured. We highlight three methodological difficulties which arise when trying to draw conclusions over mobility trends - concerning the extent of controls for life course effects; the quality of data resources; and the measurement of stratification positions. After constructing a longitudinal dataset which attempts to confront these difficulties, our analyses provide robust evidence which challenges hitherto more popular, politicised claims of declining or unchanging mobility. By contrast, our findings suggest that Britain has moved, and continues to move, steadily towards increasing equality in the relationship between occupational attainment and parental background.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Rainer Lüdtke ◽  
Stefan N. Willich ◽  
Thomas Ostermann

Background. Cohort studies have reported that patients improve considerably after individualised homeopathic treatment. However, these results may be biased by regression to the mean (RTM).Objective. To evaluate whether the observed changes in previous cohort studies are due to RTM and to estimate RTM adjusted effects.Methods. SF-36 quality-of-life (QoL) data from a German cohort of 2827 chronically diseased adults treated by a homeopath were reanalysed by Mee and Chua’s modifiedt-test.Results. RTM adjusted effects, standardized by the respective standard deviation at baseline, were 0.12 (95% CI: 0.06–0.19,P<0.001) in the mental and 0.25 (0.22–0.28,P<0.001) in the physical summary score. Small-to-moderate effects were confirmed for the most individual diagnoses in physical, but not in mental component scores. Under the assumption that the true population mean equals the mean of all actually diseased patients, RTM adjusted effects were confirmed for both scores in most diagnoses.Conclusions. Changes in QoL after treatment by a homeopath are small but cannot be explained by RTM alone. As all analyses made conservative assumptions, true RTM adjusted effects are probably larger than presented.


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