scholarly journals Clove oil as anaesthetic for juveniles of matrinxã Brycon cephalus (Gunther, 1869)

2003 ◽  
Vol 33 (5) ◽  
pp. 943-947 ◽  
Author(s):  
Luis Antônio Kioshi Aoki Inoue ◽  
Cristiano dos Santos Neto ◽  
Gilberto Moraes
Keyword(s):  
Side Effects ◽  
Recovery Time ◽  
Upright Position ◽  
Clove Oil ◽  
Fish Farms ◽  
Methane Sulfonate ◽  
Tricaine Methane Sulfonate ◽  
Oil Concentration ◽  
Corneal Damage ◽  
The Times

Many chemicals have been used as anaesthetics in fish farms and fish biology laboratories to keep the fish immobilized during handling procedures and to prevent accidents and animal stress. In Brazil, tricaine methane sulfonate (MS 222), quinaldine sulfate, benzocaine, and phenoxyethanol are the most common fish anaesthetics used to prevent fish stress during handling, but many side effects such as body and gill irritations, corneal damage and general risks of intoxication have been reported. Clove oil is a natural product proposed as an alternative fish anaesthetic by many researchers and it has been used in many countries with great economic advantages and no apparent toxic properties. In this work, we assessed the suitability of clove oil to anaesthetize matrinxã. Sixty-three juveniles of matrinxã were exposed to seven anaesthetic batches of clove oil (pharmaceutical grade) namely 18, 20, 30, 40, 50, 60, and 70 mg/L. The times to reach total loss of equilibrium and to recover the upright position were measured. Clove oil concentration about 40 mg/L was enough to anaesthetize the fish in approximately one minute and the recovery time was independent in regard to anaesthetic concentration.

scholarly journals RESPONS IKAN ZEBRA EKOR HITAM (Dascyllus melanurus) TERHADAP PENGGUNAAN ANAESTESI MINYAK CENGKEH SEBAGAI ALAT BANTU PENANGKAPAN PADA SKALA LABORATORIUM (Response of Zebra Fish Blacktail (Dascyllus melanurus) on the use of Clove Oil Anesthesia as a ...

2017 ◽  
Vol 8 (1) ◽  
pp. 51
Author(s):  
Sri Wahyuni Rahim
Keyword(s):  
Induction Time ◽  
Recovery Time ◽  
Sea Water ◽  
Negative Impact ◽  
Anesthetic Technique ◽  
Clove Oil ◽  
Zebra Fish ◽  
Synthetic Chemicals ◽  
Target Fish ◽  
Oil Concentration

<p align="center"><strong><em>ABSTRACT</em></strong></p><p><em>The process of catching fish using an anesthetic technique is inseparable from the use of synthetic chemicals (cyanide) that negatively impact the target fish, non-target and on coral reefs. One way to reduce the negative impact of cyanide is to look for another alternative that are environmental friendly. One alternative is clove oil. The </em><em>objectives of study are </em><em>to determine the optimal concentration of clove oil on the induction and recovery time of zebra fish blacktail (Dascyllus melanurus).</em><em> </em><em>Samples used were captured without using cyanide.  A tank with dimension 30 x 40 x 50 m filled with sea water was mixed with different concentrations of clove oil.</em><em> </em><em>The experiment was repeated three times. Observation of the behavior was performed to determine the induction and recovery time.</em><em> </em><em>The results showed the longest induction time were observed in concentration of 20 ppm with an average time of 321.33 seconds and the fastest time of induction was recognized in concentration of 60 ppm with an average time of 28.33 seconds. Longest recovery time was at a concentration of 20 ppm with an average time of 188.33 seconds and the fastest recovery time was at a concentration of 40 ppm with an average time of 80.67 seconds. Clove oil concentration of 40 ppm was most effective in fishing with induction time ranged from 40-48 seconds, and recovery time ranges from 72-91 seconds.</em><em></em></p><p class="TubuhTulisanAll"><strong><em>Keywords:</em></strong><strong><em> </em></strong><em>clove oil, induction time, recovery time</em><em>, </em><em>zebra fish blacktail</em><em></em></p><p align="center"><strong>ABSTRAK</strong></p><p class="Abstrakisi">Proses penangkapan ikan dengan menggunakan teknik pembiusan tidak terlepas dari penggunaan bahan kimia sintetik (sianida) yang berdampak negatif terhadap ikan target, non-target serta pada terumbu karang. Salah satu cara untuk mengurangi dampak negatif dari sianida adalah dengan mencari alternatif lain yang ramah lingkungan. Salah satu alternatif yang digunakan adalah minyak cengkeh. Penelitian ini bertujuan untuk mengetahui konsentrasi optimal minyak cengkeh terhadap waktu induksi dan waktu pulih ikan zebra blacktail (<em>Dascyllus melanurus</em>). Sampel yang digunakan ditangkap tanpa mengggunakan sianida.  Akuarium berukuran 30 x 40 x 50 m diisi dengan air laut. Kemudian dimasukkan beberapa konsentrasi minyak cengkeh yang berbeda (20, 30, 40, 50 dan 60 ppm). Pengamatan terhadap tingkah laku dilakukan untuk menentukan waktu induksi dan waktu pulih. Hasil penelitian menunjukkan waktu induksi terlama terdapat pada konsentrasi 20 ppm dengan waktu rata-rata 321,33 detik dan waktu induksi tercepat terdapat pada konsentrasi 60 ppm dengan waktu rata-rata 28,33 detik. Waktu pulih terlama terdapat pada konsentrasi 20 ppm dengan waktu rata-rata 188,33 detik dan waktu pulih tercepat terdapat pada konsentrasi 40 ppm dengan waktu rata-rata 80,67 detik. Penelitian ini menunjukkan bahwa konsentrasi minyak cengkeh 40 ppm merupakan konsentrasi yang paling efektif dalam proses penangkapan ikan zebra blacktail (<em>Dascyllus melanurus</em>) dengan waktu induksi berkisar 40 – 48 detik dan waktu pulih berkisar 72 – 91 detik.</p><p class="TubuhTulisanAll" align="left"><strong>Kata kunci:</strong>  minyak cengkeh, waktu Induksi, waktu pulih, ikan zebra blacktail</p>

scholarly journals Prophylactic corneal cross-linking in LASIK surgery: effects on visual outcome and recovery time

2020 ◽  
Vol 17 (1) ◽  
pp. 61-68
Author(s):  
Dominique Clare Oh ◽  
Yiong Huak Chan ◽  
Sao Bing Lee ◽  
Jovina Li Shuen See
Keyword(s):  
Visual Acuity ◽  
Side Effects ◽  
Recovery Time ◽  
Visual Outcome ◽  
Cross Linking ◽  
Safe Procedure ◽  
Distance Visual Acuity ◽  
Visual Outcomes ◽  
Group A ◽  
Group B

Introduction: Collagen cross-linking is a useful adjunct in preventing corneal ectasia after laser-assisted in situ keratomileusis (LASIK). This study aimed to evaluate whether prophylactic cross-linking in IntraLase LASIK affects optimum visual outcome and recovery time in the immediate post-surgery period and is associated with any side effects. Methods: This was a retrospective case study on the right eyes of 100 Chinese subjects aged 18 to 40 years who underwent IntraLase LASIK. Fifty subjects who underwentcross-linking after completing LASIK (Group A) were compared with 50 subjects who did not undergo LASIK (Group B). Cases were evaluated for pre- and post-operative spherical equivalent, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), recovery time and presence of side effects. Results: At 1 week post-LASIK, mean (SD) UDVA of Group A subjects was poorer than Group B, at 1.05 (0.19) vs 1.17 (0.19) (p = 0.036); however, there was no significant difference in CDVA (p = 0.095). By 1 month post-LASIK, differences in both UDVA and CDVA were insignificant (p = 0.055, 0.106, respectively). Mean recovery time was 2.72 (95% confidence interval [CI] = 0.64-4.7) days longer in Group A (p = 0.010), although by 1 month post-LASIK, both groups were able to achieve CDVA equal to or better than that achieved pre-LASIK. Incidence of mild inflammation and dry eyes post-LASIK was similar in both groups (p = 1.00, 0.749, respectively); no other complications were observed. Conclusion: No differences in visual outcomes at and occurrence of side effects at 1 month post-LASIK were observed between subjects who underwent cross-linking prior to refractive surgery and those who did not. However, the group that underwent cross-linking had a slightly longer mean recovery time. Our study supports prophylactic cross-linking as a safe procedure that does not affect immediate visual outcomes among the Chinese population when used in adjunct with LASIK surgery.

scholarly journals Comparison of Ketamine and Pentazocine with Fentanyl and Propofol combination for anaesthesia during laparoscopic tubal ligation

2019 ◽  
Vol 8 (4) ◽  
pp. 1525
Author(s):  
Ovais Nazir ◽  
Asif Hussain Bhat ◽  
Hamid Yatoo ◽  
Sanjeevni Gupta ◽  
Rajesh Misra
Keyword(s):  
Side Effects ◽  
Recovery Time ◽  
Postoperative Nausea And Vomiting ◽  
Rapid Onset ◽  
Tubal Ligation ◽  
Onset Of Action ◽  
Anaesthetic Agents ◽  
Minimally Invasive Surgical ◽  
Group I ◽  
Group Ii

Background: Laparoscopic tubal ligation have advantages of minimally invasive surgical technique, without risk of major haemorrhage, early postoperative ambulation and alimentation, making it suitable for ambulatory surgery. The choice of aneasthesia for laparoscopic ligation hence should consider the anaesthetic agents with a rapid onset of action and fast recovery time, with minimal problems for intraoperative control of haemodynamic, airway and pain relief as well as take consideration of the safety, quality, efficacy, and utilization of resources available to the given situation.Methods: A total of 100 patients aged from 18 to 45 years who were scheduled to undergo laparoscopic tubal ligation  were divided into Group I-  Ketamine plus pentazocine group (n=50), Group II- Propofol plus fentanyl group (n=50) and studied  for the intraoperative parameters (hemodynamic and respiratory profile), recovery time, postoperative side effects and discharge time.Results: Intraoperatively MAP and HR were consistently higher in group I as compared to group II. Incidence of apnea and need for bag and mask ventilation was significantly more in Group II than in Group I as was the incidence of Bradycardia. Postoperative nausea and vomiting, psychomimetic effects were significantly more in Group I than in Group II. The time to reach modified PADSS ≥9 (discharge time) was significantly longer in group I (140.3±12.82 min than in group II 102.2±9.2 min), P<0.01.Conclusions: Combination of ketamine and pentazocine gives good anaesthetic conditions during procedure with less incidence of airway and haemodynamic complications intraoperatively but more incidence of postoperative side effects like nausea, vomiting, psycomimetic effects, and time to meet discharge criteria, compared to propofol plus fentanyl.

scholarly journals The Use of Natural Anesthetic Ingredients for Clove Oil in Transportation of Juvenile Swordtail (Xiphophorus helleri)

2021 ◽  
pp. 1-8
Author(s):  
Kelvin Manik ◽  
Walim Lili ◽  
. Rosidah ◽  
Roffi Grandiosa
Keyword(s):  
Water Quality ◽  
Survival Rate ◽  
Effective Treatment ◽  
Induction Time ◽  
Recovery Time ◽  
Block Design ◽  
Effective Concentration ◽  
Clove Oil ◽  
Xiphophorus Helleri ◽  
Randomized Block Design

This research aims to determine the most effective concentration of clove oil and the best period in the transportation of swordtail (Xiphophorius helleri) with the highest survival rate. This research used the factorial randomized block design (FRBD) which consisting of four treatments of concentration (10 x 10-3 mL, 13 x 10-3 mL, 16 x 10-3 mL), three treatments of duration (3 hours, 5 hours, 7 hours), and repeated three times. The measured parameters are induction time, conscious recovery time, and survival rate after transportation. The results showed that the treatment of 10 x 10-3 mL with the duration of 5 hours was an effective treatment with an average induction time of 17 minutes 56 seconds, a conscious recovery time of 7 minutes 37 seconds, the survival rate of 100% at post-transportation and after 7 days of rearing is 83%. Water quality after transportation are temperature (24.6 ℃), DO (14.72 mg / L), pH (6.42) and ammonia (0.0043 mg/L).

Application of NK Cells in ASCT Peritransplantation of Multiple Myeloma

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 5427-5427
Author(s):  
Yangyi Bao ◽  
Kunyuan Guo ◽  
Yuanyuan Liu ◽  
Beilei Jiang ◽  
Zhijian Zeng ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Stem Cell ◽  
Side Effects ◽  
Nk Cells ◽  
Recovery Time ◽  
Adverse Reactions ◽  
Nk Cell ◽  
Curative Effect ◽  
Myeloma Cells

Abstract BACKGROUND Significant progress has been made in the therapy of multiple myeloma (MM) with the autologous hematopoietic stem cell transplantation(ASCT) in recent years. But the relapse after transplantation is still the main problem because the grafts are often contaminated by tumor cells and have no effect of anti myeloma. The residual myeloma cells are reduced by increasing doses of cytotoxic drug in the pretreatment. But the related mortality of ASCT is increased because of side effects and complications. Therefore, the pretreatment of MM hasn't changed very much in recent 50 years. So it is urgent to find a new pretreatment to improve curative effect which has small side effects. Natural killer (NK) cells are the principal effector cells in the innate immune system. They have extensive biological functions including anti-tumor and antiviral effects, etc. There is no report about applying NK cells as a pretreatment for ASCT to treat MM so far. In this study, NK cells were added to the pretreatment of ASCT to treat MM We hope NK cells can increase the curative effect and reduce relapse rate, but not increase the side effects. Meanwhile, they can clear myeloma cells without killing by chemotherapy drugs and to decrease infection in transplantation. OBJECTIVE To observe the safety and effectiveness of the technology by applying NK cells in peritransplantation of MM ASCT. METHODS The ages of 8 MM patients including 7 males and 1 female were 42-62 years, the median age was 51 years, 2 patents of CR and 6 patents of PR before transplantation. The method of NK cell culture: membrane embedded active factor culture system. The pretreatment mainly based on standard Melphalan or busulfan. NK cells were infused to 2 cases back 6-7days after infusing stem cell, and to 6 cases back 24-48 hours before infusing stem cells and 48 hours after chemotherapy as a part of pretreatment in transplantation. Stem cell infusion volume: the number of CD34+ cell 2.2-4.0×106/kg, the number of mononuclear cells 4.3-5.8×106/kg. NK cell infusion volume: 16-160×106/kg. we observed the adverse reactions, recovery time of blood cells and the curative effects. RESULTS There were no instances of fever, rash, diarrhea,shock, and other adverse reactions in this study. Recovery time of hematopoietic cells was: 7-14d of granulocyte and 9d of the median time, 9-34d of platelet and 11d of the median time. Fever(38-39 degrees) occurred in 6 patients during the inhibitory period of bone marrow after ASCT. Infection is the major cause of fever in patients receiving ASCT. We evaluated therapeutic effect 3 months after transplantation was 3 cases of CR and 5 cases of PR in 8 patients. The effect 6 months after transplantation was 3 cases of CR and 3 cases of PR in 6 patients. 8 patients were given thalidomide for maintenance therapy. The follow-up time was 3-29 months, median follow-up time was 11 months. Up to the present, there was no death case. CONCLUSIONS It was safe and effective to infuse autologous NK cells back in peritransplantation of MM ASCT. Storm effect of inflammatory factors didn't occur during this study. We will expand the number of cases for further clinical research to observe the long-term therapeutic effects and adverse reactions. Disclosures No relevant conflicts of interest to declare.

Intravenous Tranquillization with ECT

1975 ◽  
Vol 127 (6) ◽  
pp. 604-608 ◽  
Author(s):  
Joan Gomez ◽  
Peter Dally
Keyword(s):  
Side Effects ◽  
Recovery Time ◽  
Memory Impairment ◽  
Depression And Anxiety ◽  
Convulsive Therapy ◽  
Depressed Patients ◽  
Retrograde Memory ◽  
High Level ◽  
Electro Convulsive Therapy

SummaryForty depressed in-patients for whom electro-convulsive therapy had been prescribed were rated before treatment on depression and anxiety scales. Side effects, post-operative agitation and retrograde memory impairment were assessed in each patient after each of several treatments. Results were compared when no tranquillizer was given and when either diazepam or haloperidol was administered intravenously immediately before the anaesthetic. It was found than when ECT was given without tranquillization, the incidence and severity of post-operative agitation and of side effects were significantly greater in those patients with a high level of anxiety before treatment. Both diazepam and haloperidol were found to be effective in subduing agitation and side effects in anxious, depressed patients, but with diazepam recovery time was longer.

scholarly journals Comparison of Different Anesthetic Protocols for Morphometric Measurements of Carp (Cyprinus carpio)

2017 ◽  
Vol 1 (1) ◽  
pp. 81-84
Author(s):  
Ferhat Çağiltay ◽  
Alexander Atanasoff ◽  
Mehmet Sağlam ◽  
Soner Çağatay ◽  
Galin Nikolov ◽  
...  
Keyword(s):  
Water Quality ◽  
Recovery Time ◽  
Quality Parameters ◽  
Clove Oil ◽  
Morphometric Measurements ◽  
Anesthetic Agents ◽  
Growth Performances ◽  
Water Based ◽  
Carp Cyprinus Carpio ◽  
Water Borne

Abstract Measurement of growth performances in fish is carried out in stressful and unnatural environment. The purpose of the present investigation was to compare the effect of four different water-borne anesthetic agents. The fish (Ave. wt. 400.3±7.12 g) were divided into four groups in the glass tanks (80×48×30 cm) containing 80 L of dechlorinated bore water. For the first group we used clove oil (CO) and anesthetic agents used for other three groups were as follows: second group- lidocaine 1% (LC), III groupisoflourane (IF), IV group-halothane (HT). During experiment, water quality parameters (to, pH, О2, and NO3) were recorded. The desired concentration of anesthetics was established andinduction time, maintenance and recovery time were recorded. In two groups out of four (LC and HT) time of induction was longer approximately with 1 minute and time of recovery was shorter with 30 seconds in comparison with other two groups (CO and IF) where the time for both was 3 minutes. It could be concluded that the anesthetic time for each of the protocols used was about 4-5 minutes and allowed to measure the growth performance. An effective and safe agent is 1% lidocaine used as a water-based anesthetic at 100 mg.L-1. Isoflurane can be used with caution in small carp because there is a risk of overdose. We recommend the anesthetic clove oil protocol.

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