ENDOCRINE EFFECTS OF MASTURBATION IN MEN

1976 ◽  
Vol 70 (3) ◽  
pp. 439-444 ◽  
Author(s):  
K. PURVIS ◽  
B.-M. LANDGREN ◽  
Z. CEKAN ◽  
E. DICZFALUSY
Keyword(s):  
Plasma Levels ◽  
The Other ◽  
Endocrine Effects ◽  
Systemic Blood ◽  
Peripheral Plasma ◽  
Semen Collection ◽  
Before And After ◽  
Control Study ◽  
Healthy Males ◽  
Apparently Healthy

SUMMARY The levels of pregnenolone, dehydroepiandrosterone (DHA), androstenedione, testosterone, dihydrotestosterone (DHT), oestrone, oestradiol, cortisol and luteinizing hormone (LH) were measured in the peripheral plasma of a group of young, apparently healthy males before and after masturbation. The same steroids were also determined in a control study, in which the psychological anticipation of masturbation was encouraged, but the physical act was not carried out. The plasma levels of all steroids were significantly increased after masturbation, whereas steroid levels remained unchanged in the control study. The most marked changes after masturbation were observed in pregnenolone and DHA levels. No alterations were observed in the plasma levels of LH. Both before and after masturbation plasma levels of testosterone were significantly correlated to those of DHT and oestradiol, but not to those of the other steroids studied. On the other hand, cortisol levels were significantly correlated to those of pregnenolone, DHA, androstenedione and oestrone. In the same subjects, the levels of pregnenolone, DHA, androstenedione, testosterone and DHT in seminal plasma were also estimated; they were all significantly correlated to the levels of the corresponding steroid in the systemic blood withdrawn both before and after masturbation. As a practical consequence, the results indicate that whenever both blood and semen are analysed, blood sampling must precede semen collection.

SECRETION OF DIHYDROTESTOSTERONE BY HUMAN PROSTATE IN BENIGN PROSTATIC HYPERTROPHY

1974 ◽  
Vol 77 (2) ◽  
pp. 401-407 ◽  
Author(s):  
J. A. Mahoudeau ◽  
A. Delassalle ◽  
H. Bricaire
Keyword(s):  
Plasma Levels ◽  
Benign Prostatic Hypertrophy ◽  
Prostatic Hypertrophy ◽  
Human Prostate ◽  
Control Subjects ◽  
Peripheral Plasma ◽  
Significant Difference ◽  
Before And After ◽  
The Mean ◽  
And Control

ABSTRACT Plasma levels of testosterone (T) and 5α-dihydrotestosterone (DHT) were determined by radioimmunoassay in 29 patients with benign prostatic hypertrophy (BPH) and in 56 control men of various ages. No significant difference was found in T, DHT nor DHT/T ratio between BPH and control subjects of similar age. Plasma DHT was higher in the prostatic than in the peripheral veins in 8/9 patients with BPH during laparotomy, indicating a prostatic secretion of DHT. No difference in the mean T nor the mean DHT was found in peripheral plasma before and after adenomectomy.

STUDIES ON HUMAN ADRENAL STEROIDS: 1. THE EFFECT OF CORTICOTROPIN ON COMPONENTS OF THE FREE AND CONJUGATED PLASMA C2l ADRENAL STEROID FRACTIONS

1956 ◽  
Vol 34 (2) ◽  
pp. 146-157 ◽  
Author(s):  
C. M. Southcott ◽  
S. K. Gandossi ◽  
A. D. Barker ◽  
H. E. Bandy ◽  
Hamish McIntosh ◽  
...  
Keyword(s):  
Individual Variation ◽  
Preliminary Data ◽  
Plasma Levels ◽  
Adrenal Steroids ◽  
Adrenal Steroid ◽  
Peripheral Plasma ◽  
Before And After ◽  
Normal Human ◽  
Considerable Individual Variation

The free and conjugated adrenal steroid fractions of peripheral plasma from12 normal human males were studied. Specimens were withdrawn before and after the administration of corticotropin. Hydrocortisone was identified chemically and some evidence was obtained for the presence of corticosterone. Hydrocortisone levels showed a marked but variable increase after corticotropin treatment. In some cases the administration of corticotropin resulted in the appearance of an unconjugated compound which may have been a tetrahydro derivative of cortisone or hydrocortisone. A method for studying the conjugated fraction was developed and preliminary data indicated that four components were present in some specimens after hydrolysis with β-glucuronidase. The level of these conjugates appeared to increase after treatment with corticotropin. In general, the response to a given dose of corticotropin showed considerable individual variation in the plasma levels of the components of both the free and conjugated corticosteroid fractions.

The effect of ACTH stimulation on plasma steroids in two patients with congenital hypoaldosteronism and in their relatives

1982 ◽  
Vol 99 (2) ◽  
pp. 245-250 ◽  
Author(s):  
S. L. S. Drop ◽  
I. M. E. Frohn-Mulder ◽  
H. K. A. Visser ◽  
W. G. Sippell ◽  
H. G. Dörr ◽  
...  
Keyword(s):  
Plasma Levels ◽  
Zona Glomerulosa ◽  
The Other ◽  
Type I ◽  
Type Ii ◽  
Acth Stimulation ◽  
Oxidase Deficiency ◽  
Before And After ◽  
Plasma Steroids ◽  
Deficiency Type

Abstract. In two children with isolated congential hyperreninaemic hypoaldosteronism, as well as in their relatives, plasma levels of aldosterone (Aldo), corticosterone (B), deoxycorticosterone (DOC), 18-OH-B and 18-OH-DOC were measured before and after an iv bolus of 0.25 mg Synacthen® (Ciba). A corticosterone methyl oxidase deficiency type II was demonstrated in one child. Her normoreninaemic parents (no consanguinity) had plasma values consistent with heterozygosity. The results in the other child and one asymptomatic sib were compatible with a partial corticosterone methyl oxidase deficiency type I. His parents were consanguine but had normal Aldo levels. Overnight dexamethasone administration did not suppress any of the steroids measured except cortisol, suggesting synthesis of these steroids by the zona glomerulosa.

PERIPHERAL PLASMA LEVELS OF OESTRONE AND PROGESTERONE IN PREGNANT COWS TREATED WITH DEXAMETHASONE

1972 ◽  
Vol 71 (4) ◽  
pp. 731-742 ◽  
Author(s):  
Lars-Eric Edqvist ◽  
Lars Ekman ◽  
Börje Gustafsson ◽  
Sten-Olof Jacobsson ◽  
Elof D. B. Johansson ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Peripheral Blood ◽  
Plasma Levels ◽  
The Other ◽  
Dexamethasone Treatment ◽  
Peripheral Plasma ◽  
White Breed ◽  
Peripheral Blood Plasma

ABSTRACT Eight pregnant cows of the Swedish Red and White Breed were used. Four cows at 248–250 days of pregnancy received 10 or 20 mg of dexamethasone1) intramuscularly and a second dose equal to the first 3 to 6 days later. Two cows at day 75 and two cows at days 147 and 150 of pregnancy received daily injections of 40 mg of dexamethasone for 7 to 12 days. All late pregnant cows delivered living calves 12 to 68 hours after the second injection. One cow at day 150 of pregnancy aborted on the 6th day from the start of treatment. In all the other cows dead foetuses were found. An increase in oestrone and a decrease in progesterone in peripheral blood plasma were observed in all late pregnant cows after the dexamethasone treatment. The increase in oestrone preceded the decrease in progesterone. The cow pregnant for 150 days which aborted showed decreased plasma levels of progesterone before abortion. No pronounced changes in the levels of progesterone were observed in the other three early pregnant cows. The peripheral plasma levels of oestrone showed no increase in any of the early and mid-term pregnant cows.

STUDIES ON HUMAN ADRENAL STEROIDS: 1. THE EFFECT OF CORTICOTROPIN ON COMPONENTS OF THE FREE AND CONJUGATED PLASMA C2l ADRENAL STEROID FRACTIONS

1956 ◽  
Vol 34 (1) ◽  
pp. 146-157
Author(s):  
C. M. Southcott ◽  
S. K. Gandossi ◽  
A. D. Barker ◽  
H. E. Bandy ◽  
Hamish McIntosh ◽  
...  
Keyword(s):  
Individual Variation ◽  
Preliminary Data ◽  
Plasma Levels ◽  
Adrenal Steroids ◽  
Adrenal Steroid ◽  
Peripheral Plasma ◽  
Before And After ◽  
Normal Human ◽  
Considerable Individual Variation

The free and conjugated adrenal steroid fractions of peripheral plasma from12 normal human males were studied. Specimens were withdrawn before and after the administration of corticotropin. Hydrocortisone was identified chemically and some evidence was obtained for the presence of corticosterone. Hydrocortisone levels showed a marked but variable increase after corticotropin treatment. In some cases the administration of corticotropin resulted in the appearance of an unconjugated compound which may have been a tetrahydro derivative of cortisone or hydrocortisone. A method for studying the conjugated fraction was developed and preliminary data indicated that four components were present in some specimens after hydrolysis with β-glucuronidase. The level of these conjugates appeared to increase after treatment with corticotropin. In general, the response to a given dose of corticotropin showed considerable individual variation in the plasma levels of the components of both the free and conjugated corticosteroid fractions.

Arthroscopy in Arthrosis: Is It Worth it? A case Presentation

2018 ◽  
Vol 69 (8) ◽  
pp. 2232-2235
Author(s):  
Marius Moga ◽  
Mark Edward Pogarasteanu ◽  
Antoine Edu
Keyword(s):  
Clinical Status ◽  
Loose Body ◽  
Point Of View ◽  
The Other ◽  
Joint Range Of Motion ◽  
Objective Evidence ◽  
Before And After ◽  
Total Knee ◽  
Joint Range

The role of arthroscopy in incipient and mild arthrosis, even combined with proximal tibial ostetomy, is well known and well documented. On the other hand, its role in the treatment of advanced arthrosis of the large joints, especially the knee, is a subject of controversy. The proponents of the use of arthroscopy in advanced arthrosis claim that meniscectomy, synovectomy, ostophytectomy, chondral lesion stabilization, arthroscopic release, plica and loose body removal greatly improve the quality of life for most patients, especially if followed by the use of viscoelastic injection, by diminishing pain and improving joint range of motion. The opponents claim that, even though the advantages are clear in the cases that refuse arthroplasty, in all the other cases the surgical indication should be total knee arthroplasty, as the clinical relief is temporary, but with all the risks of a surgical intervention. We have conducted an overview of the recent literature, in order to find objective evidence to sustain either point of view. We focused on articles published that included an objective measurement of before and after clinical status through clinical scores and objective measurements. We also focused on the follow-up period and on the evolution of the pathology after arthroscopy.

Antimicrobial Effect of 940 nm Diode Laser based on Photolysis of Hydrogen Peroxide in the Treatment of Periodontal Disease

2018 ◽  
Vol 69 (8) ◽  
pp. 2081-2088 ◽  
Author(s):  
Alin Alexandru Odor ◽  
Edwin Sever Bechir ◽  
Deborah Violant ◽  
Victoria Badea
Keyword(s):  
Hydrogen Peroxide ◽  
Laser Therapy ◽  
Diode Laser ◽  
Antimicrobial Effect ◽  
The Other ◽  
Control Group ◽  
Group 4 ◽  
Periodontal Bacteria ◽  
Severe Periodontitis ◽  
Before And After

Moderate and severe periodontitis represents a challenge in the non-surgical periodontal therapy. Due to the lack of evidence regarding the antimicrobial effectiveness of 940 nm diode laser in periodontal treatment, this study aimed to evaluate the antimicrobial effect of hydrogen peroxide (H2O2) photolysis performed with 940 nm diode laser in the treatment of moderate and severe periodontitis. Twenty-five patients with 100 teeth were selected for this pilot study. The test teeth were randomly assigned to one of the four treatment groups: Group 1: scaling and root planning (SRP) (control group); and the following experimental groups: Group 2: H2O2; Group 3: 940 nm diode laser therapy; Group 4: 940 nm diode laser therapy and H2O2. Clinical examinations, like probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) were performed before and after the treatment. The microbiological evaluation, effectuated before and after the treatment, included nine periodontal bacteria species and investigated by means of real-time PCR assay. The clinical and bacterial differences in the tested groups, was assessed between control group and the other three experimental groups, as well as between the experimental groups. The total bacteria load was reduced for all four studied groups. Group 4 (diode laser + H2O2) showed significant bacterial reduction of the major periodontal bacteria like Pg., Tf., Td., Pi., Pm., Fn (p[0.001) than the other 3 groups (p]0.001). Also the periodontal clinical parameters, like PD, CAL and BOP showed a significant reduction after the photolysis of H2O2 with the 940 nm diode laser (p[0.001). Differences between tested groups showed a significant beneficial results in regard to Group 4.It is suggested that the photoactivation of H2O2 with the 940 nm diode laser can be used successfully in adjunctive to the non-surgical periodontal treatment as a bactericidal tool.

scholarly journals Management of chronic periodontitis: an interdisciplinary approach

2016 ◽  
Vol 4 (2) ◽  
pp. 65
Author(s):  
Sneha Dani ◽  
Savitha A.N ◽  
Kenneth Tan ◽  
Anand Naik ◽  
Charan Chhatrala ◽  
...  
Keyword(s):  
Public Interest ◽  
Orthodontic Treatment ◽  
Interdisciplinary Approach ◽  
Primary Objective ◽  
Periodontal Therapy ◽  
The Other ◽  
Periodontal Health ◽  
Orthodontic Therapy ◽  
Single Tooth ◽  
Before And After

Objective: In recent years, advances in technique as well as a growing public interest in developing and maintaining a healthy and attractive smile, has resulted in a greater understanding of the interrelationships between periodontics and orthodontics. The primary objective of periodontal therapy is to restore and maintain the health and integrity of the attachment apparatus of teeth. In adults, the loss of teeth or periodontal support can result in pathological teeth migration involving either a single tooth or a group of teeth. This may result in the development of a diastema, incisal proclination, rotation with collapse of the posterior occlusion.Materials and methods: This case report is of a 32 year old female patient who reported with swollen gums, generalized spacing between the teeth and extruded upper anterior tooth. Periodontal therapy followed by fixed orthodontic therapy was planned.Results: At the end of 2 years a stable healthy periodontium was established that was both functional and esthetic.Conclusion: Adjunctive orthodontic therapy is often necessary for successful restoration of periodontal health. On the other hand, successful orthodontic treatment will depend on the periodontal preparation before and after treatment and the maintenance of periodontal health throughout all phases of mechano-therapy.

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