scholarly journals Peripheral plasma levels of LH, testosterone, and estradiol-17.BETA. before and after orchiopexy in unilaterally cryptorchid dogs.

1990 ◽  
Vol 52 (1) ◽  
pp. 179-181 ◽  
Author(s):  
Eiichi KAWAKAMI ◽  
Toshihiko TSUTSUI ◽  
Akira OGASA
Keyword(s):  
Plasma Levels ◽  
Peripheral Plasma ◽  
Before And After

SECRETION OF DIHYDROTESTOSTERONE BY HUMAN PROSTATE IN BENIGN PROSTATIC HYPERTROPHY

1974 ◽  
Vol 77 (2) ◽  
pp. 401-407 ◽  
Author(s):  
J. A. Mahoudeau ◽  
A. Delassalle ◽  
H. Bricaire
Keyword(s):  
Plasma Levels ◽  
Benign Prostatic Hypertrophy ◽  
Prostatic Hypertrophy ◽  
Human Prostate ◽  
Control Subjects ◽  
Peripheral Plasma ◽  
Significant Difference ◽  
Before And After ◽  
The Mean ◽  
And Control

ABSTRACT Plasma levels of testosterone (T) and 5α-dihydrotestosterone (DHT) were determined by radioimmunoassay in 29 patients with benign prostatic hypertrophy (BPH) and in 56 control men of various ages. No significant difference was found in T, DHT nor DHT/T ratio between BPH and control subjects of similar age. Plasma DHT was higher in the prostatic than in the peripheral veins in 8/9 patients with BPH during laparotomy, indicating a prostatic secretion of DHT. No difference in the mean T nor the mean DHT was found in peripheral plasma before and after adenomectomy.

STUDIES ON HUMAN ADRENAL STEROIDS: 1. THE EFFECT OF CORTICOTROPIN ON COMPONENTS OF THE FREE AND CONJUGATED PLASMA C2l ADRENAL STEROID FRACTIONS

1956 ◽  
Vol 34 (2) ◽  
pp. 146-157 ◽  
Author(s):  
C. M. Southcott ◽  
S. K. Gandossi ◽  
A. D. Barker ◽  
H. E. Bandy ◽  
Hamish McIntosh ◽  
...  
Keyword(s):  
Individual Variation ◽  
Preliminary Data ◽  
Plasma Levels ◽  
Adrenal Steroids ◽  
Adrenal Steroid ◽  
Peripheral Plasma ◽  
Before And After ◽  
Normal Human ◽  
Considerable Individual Variation

The free and conjugated adrenal steroid fractions of peripheral plasma from12 normal human males were studied. Specimens were withdrawn before and after the administration of corticotropin. Hydrocortisone was identified chemically and some evidence was obtained for the presence of corticosterone. Hydrocortisone levels showed a marked but variable increase after corticotropin treatment. In some cases the administration of corticotropin resulted in the appearance of an unconjugated compound which may have been a tetrahydro derivative of cortisone or hydrocortisone. A method for studying the conjugated fraction was developed and preliminary data indicated that four components were present in some specimens after hydrolysis with β-glucuronidase. The level of these conjugates appeared to increase after treatment with corticotropin. In general, the response to a given dose of corticotropin showed considerable individual variation in the plasma levels of the components of both the free and conjugated corticosteroid fractions.

ENDOCRINE EFFECTS OF MASTURBATION IN MEN

1976 ◽  
Vol 70 (3) ◽  
pp. 439-444 ◽  
Author(s):  
K. PURVIS ◽  
B.-M. LANDGREN ◽  
Z. CEKAN ◽  
E. DICZFALUSY
Keyword(s):  
Plasma Levels ◽  
The Other ◽  
Endocrine Effects ◽  
Systemic Blood ◽  
Peripheral Plasma ◽  
Semen Collection ◽  
Before And After ◽  
Control Study ◽  
Healthy Males ◽  
Apparently Healthy

SUMMARY The levels of pregnenolone, dehydroepiandrosterone (DHA), androstenedione, testosterone, dihydrotestosterone (DHT), oestrone, oestradiol, cortisol and luteinizing hormone (LH) were measured in the peripheral plasma of a group of young, apparently healthy males before and after masturbation. The same steroids were also determined in a control study, in which the psychological anticipation of masturbation was encouraged, but the physical act was not carried out. The plasma levels of all steroids were significantly increased after masturbation, whereas steroid levels remained unchanged in the control study. The most marked changes after masturbation were observed in pregnenolone and DHA levels. No alterations were observed in the plasma levels of LH. Both before and after masturbation plasma levels of testosterone were significantly correlated to those of DHT and oestradiol, but not to those of the other steroids studied. On the other hand, cortisol levels were significantly correlated to those of pregnenolone, DHA, androstenedione and oestrone. In the same subjects, the levels of pregnenolone, DHA, androstenedione, testosterone and DHT in seminal plasma were also estimated; they were all significantly correlated to the levels of the corresponding steroid in the systemic blood withdrawn both before and after masturbation. As a practical consequence, the results indicate that whenever both blood and semen are analysed, blood sampling must precede semen collection.

STUDIES ON HUMAN ADRENAL STEROIDS: 1. THE EFFECT OF CORTICOTROPIN ON COMPONENTS OF THE FREE AND CONJUGATED PLASMA C2l ADRENAL STEROID FRACTIONS

1956 ◽  
Vol 34 (1) ◽  
pp. 146-157
Author(s):  
C. M. Southcott ◽  
S. K. Gandossi ◽  
A. D. Barker ◽  
H. E. Bandy ◽  
Hamish McIntosh ◽  
...  
Keyword(s):  
Individual Variation ◽  
Preliminary Data ◽  
Plasma Levels ◽  
Adrenal Steroids ◽  
Adrenal Steroid ◽  
Peripheral Plasma ◽  
Before And After ◽  
Normal Human ◽  
Considerable Individual Variation

The free and conjugated adrenal steroid fractions of peripheral plasma from12 normal human males were studied. Specimens were withdrawn before and after the administration of corticotropin. Hydrocortisone was identified chemically and some evidence was obtained for the presence of corticosterone. Hydrocortisone levels showed a marked but variable increase after corticotropin treatment. In some cases the administration of corticotropin resulted in the appearance of an unconjugated compound which may have been a tetrahydro derivative of cortisone or hydrocortisone. A method for studying the conjugated fraction was developed and preliminary data indicated that four components were present in some specimens after hydrolysis with β-glucuronidase. The level of these conjugates appeared to increase after treatment with corticotropin. In general, the response to a given dose of corticotropin showed considerable individual variation in the plasma levels of the components of both the free and conjugated corticosteroid fractions.

CHANGES IN THE CONCENTRATION OF PITUITARY AND STEROID HORMONES IN THE FOLLICULAR FLUID OF HUMAN GRAAFIAN FOLLICLES THROUGHOUT THE MENSTRUAL CYCLE

1975 ◽  
Vol 64 (3) ◽  
pp. 555-571 ◽  
Author(s):  
K. P. McNATTY ◽  
W. M. HUNTER ◽  
A. S. McNEILLY ◽  
R. S. SAWERS
Keyword(s):  
Menstrual Cycle ◽  
Steroid Hormones ◽  
Follicular Fluid ◽  
Follicle Stimulating Hormone ◽  
Secretory Activity ◽  
Follicular Phase ◽  
Hormonal Changes ◽  
Peripheral Plasma ◽  
Before And After ◽  
Late Follicular Phase

SUMMARY The concentrations of FSH, LH, prolactin, oestradiol and progesterone were measured in peripheral plasma and follicular fluid of women throughout the menstrual cycle. With the exception of prolactin, concentrations of pituitary and steroid hormones in follicular fluid correlated with those in peripheral plasma. Follicle-stimulating hormone was present in a greater number of small follicles ( < 8 mm) during or just after the peaks of FSH in peripheral plasma. During the mid-follicular phase the concentration of both FSH and oestradiol in fluid from large follicles ( ≥ 8 mm) was high. During the late follicular phase the large follicles ( ≥ 8 mm) contained high amounts of progesterone in addition to oestradiol, low physiological levels of prolactin, and concentrations of LH and FSH about 30 and 60% respectively of those found in plasma. By contrast no large 'active' follicles ( ≥ 8 mm) were found during the luteal phase although many contained both LH and FSH. Luteinizing hormone was present in a proportion of small follicles ( < 8 mm) during the late follicular and early luteal but not at other stages of the menstrual cycle. It is suggested that a precise sequence of hormonal changes occur within the microenvironment of the developing Graafian follicle; the order in which they occur may be of considerable importance for the growth of that follicle and secretory activity of the granulosa cells both before and after ovulation.

Acute cold stress in rheumatoid arthritis inadequately activates stress responses and induces an increase of interleukin 6

2008 ◽  
Vol 68 (4) ◽  
pp. 572-578 ◽  
Author(s):  
R H Straub ◽  
G Pongratz ◽  
H Hirvonen ◽  
T Pohjolainen ◽  
M Mikkelsson ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Stress Response ◽  
Cold Stress ◽  
Stress Responses ◽  
Plasma Levels ◽  
Acute Stress ◽  
Whole Body ◽  
Cold Therapy ◽  
Before And After ◽  
Sympathetic Stress

Objective:Acute stress in patients with rheumatoid arthritis (RA) should stimulate a strong stress response. After cryotherapy, we expected to observe an increase of hormones of the adrenal gland and the sympathetic nervous system.Methods:A total of 55 patients with RA were recruited for whole-body cryotherapy at −110°C and −60°C, and local cold therapy between −20°C and −30°C for 7 days. We measured plasma levels of steroid hormones, neuropeptide Y (sympathetic marker), and interleukin (IL)6 daily before and after cryotherapy.Results:In both therapy groups with/without glucocorticoids (GC), hormone and IL6 levels at baseline and 5 h after cold stress did not change over 7 days of cryotherapy. In patients without GC, plasma levels of cortisol and androstenedione were highest after −110°C cold stress followed by −60°C or local cold stress. The opposite was found in patients under GC therapy, in whom, unexpectedly, −110°C cold stress elicited the smallest responses. In patients without GC, adrenal cortisol production increased relative to other adrenal steroids, and again the opposite was seen under GC therapy with a loss of cortisol and an increase of dehydroepiandrosterone. Importantly, there was no sympathetic stress response in both groups. Patients without GC and −110°C cold stress demonstrated higher plasma IL6 compared to the other treatment groups (not observed under GC), but they showed the best clinical response.Conclusions:We detected an inadequate stress response in patients with GC. It is further shown that the sympathetic stress response was inadequate in patients with/without GC. Paradoxically, plasma levels of IL6 increased under strong cold stress in patients without GC. These findings confirm dysfunctional stress axes in RA.

Chronic physical stress differences between genders in a military training on the Amazon jungle

2015 ◽  
Vol 11 (1) ◽  
pp. 17-21
Author(s):  
Y.R. de Souza ◽  
F.B. Feitosa
Keyword(s):  
Plasma Levels ◽  
Scientific Literature ◽  
Military Training ◽  
Female Gender ◽  
Physical Stress ◽  
Male Gender ◽  
Normal Range ◽  
Male And Female ◽  
Normal Limits ◽  
Before And After

This study aimed to investigate the gender difference in the manifestation of physical stress in a strenuous military training on Amazon jungle, using alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH) markers, measured before and after an adaptation to jungle training. The sample consisted of 49 military volunteers, 35 male and 14 female, recently moved to the Amazon region. All plasma levels rose after the training. Serum ALT (male and female) and AST (male and female), although borderline, remained within normal limits. Already plasma levels of CK (both male and female) and LDH (male and female) largely exceeded the normal range. The average of all markers listed in female gender remained below the levels of the male gender. However, significant differences in biomarkers ALT, AST and CK between genders were found. The study points out that, in a jungle environment, biometric markers ALT, AST, CK and LDH are efficient for monitoring chronic physical stress in both genders, when used in combination. The influence of the weather on the occurrence of physical stress in unacclimated people of both genders, and the lower responses in the levels of ALT, AST, LDH and CK in females were discussed basing on the scientific literature.

scholarly journals Malondialdehyde Levels in Preeclampsia before and after Delivery

1970 ◽  
pp. 143
Author(s):  
Harold Rumopa ◽  
Freddy W. Wagey ◽  
Eddy Suparman
Keyword(s):  
Oxidative Stress ◽  
Plasma Levels ◽  
Cross Sectional Study ◽  
Hplc Method ◽  
Wilcoxon Test ◽  
Sectional Study ◽  
Cross Sectional ◽  
Average Value ◽  
Significant Difference ◽  
Before And After

  Objective: Determine differences plasma levels MDA in preeclampsiabefore and 2 hours after delivery.   Methods: This was an analytic cross-sectional study. Subjectconsists of 23 pregnancies with preeclampsia, where 23 bloodsamples taken before delivery and 23 were taken 2 hours afterdelivery. This study was conducted from August 2016 untilDecember 2016 at Department of Obstetrics and GynecologyFaculty of Medicine Universitas Sam Ratulangi / Prof. Dr. R. D.Kandou Hospital Manado and satellite hospital. Samples weretaken from plasma and analysed using HPLC method at Prodiaclinical laboratory.   Results: In patients with severe preeclampsia before deliverywe found average value (1.4796  0.40819 nmol/ml), minimumvalue (1.03 nmol/ml) and maximal value (2.77 nmol/ml)and 2 hours after delivery with average value (1.2470 0.34324 nmol/ml), minimum value (0.91 nmol/ml), and maximumvalue (2.47 nmol/ml). by using Wilcoxon test, we foundthere were significant differences in plasma levels of MDA (p =0.000).   Conclusion: This significant difference suggests that decreasedplasma levels of MDA 2 hours after delivery and gives the sense thatthere is a relationship between oxidative stress of cells with severepreeclampsia before and shortly after delivery, that MDA is an indicatorof oxidative stress.   Keywords: malondialdehyde, oxidative stress, peroxidation lipid,preeclampsia

Autoantibodies reacting with vasopressin and oxytocin in relation to cortisol secretion in major depression

2011 ◽  
Vol 26 (S2) ◽  
pp. 904-904
Author(s):  
F.D. Garcia ◽  
Q. Coquerel ◽  
E. Kiive ◽  
P. Déchelotte ◽  
J. Harro ◽  
...  
Keyword(s):  
Major Depression ◽  
Physical Exercise ◽  
Plasma Levels ◽  
Plasma Cortisol ◽  
Cortisol Response ◽  
Cortisol Secretion ◽  
Mild Depression ◽  
Moderate Depression ◽  
Before And After ◽  
Underlying Mechanisms

IntroductionAbnormal vasopressin (VP) and oxytocin (OT) signaling may contribute to the altered activity of the hypothalamo-pituitary-adrenal (HPA) axis in major depression; the underlying mechanisms remain uncertain.ObjectiveThis study characterized plasma levels and affinities of OT-and VP-reactive autoantibodies (autoAbs) with relation to disease severity and plasma cortisol response to physical exercise in patients with mild and moderate depression and healthy controls.MethodsPhysical exercise was used to elicit plasma cortisol response in 23 male depressive and 20 healthy subjects. All subjects were evaluated by the MADRS. Plasma levels VP-and OT-reactive IgG, IgA and IgM autoAbs were measured by ELISA, before and after the exercise, and affinity was measured by plasmon resonance.ResultsPlasma levels of OT-and VP-reactive total IgG autoAbs were lower in patients with moderate depression vs. controls and patients with mild depression. Both OT- and VP- free IgG autoAbs levels were negatively correlated with MADRS scores. Affinity values displayed 100 fold variability in both groups. Patients with moderate depression displayed blunted response of cortisol secretion to physical exercise. Baseline levels of VP total IgG and IgM autoAbs correlated negatively and of VP free IgG autoAbs correlated positively with plasma cortisol after physical exercise.ConclusionThese data show that changes of levels but not affinity of OT- and VP- reactive autoantibodies can be associated with the altered mood in subjects with moderate depression and that levels of VP-reactive autoAbs are associated with cortisol secretion.

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