scholarly journals Contagious Otherness: Translating Communicable Diseases in the Modern Italian and Francophone Novel

2021 ◽  
Author(s):  
Marta Arnaldi
Keyword(s):  
Immune System ◽  
Comparative Analysis ◽  
Medical Knowledge ◽  
Communicable Diseases ◽  
Translation Theory ◽  
National Cultures ◽  
Contagious Diseases ◽  
Course Of Action

The words contagion ('to touch together') and translation ('to carry across') share a common course of action and meaning, i.e. that of breaking what 'should be joined or joining [what] should be separate' (Douglas, 1996: 113). In a continuous yet imperceptible way, ideas of risk, corruption and error have been attached as much to the transfer of texts, beliefs and theories as to the spread of diseases. Our immune system fight against outsiders, just like national cultures can shield themselves from the foreign. Yet, if we have come to accept that contagion can be understood as a 'foundational concept in the study of [literature], of religion and of society' (Wald, 2007: 2), translation's epidemiological dimensions have remained relatively unexplored. What do the art of translation and epidemiological science have in common, and how can they inform one another? Why is contagion culturally valuable, but physiologically destructive? How can translation theory contribute to the shaping of a novel, biocultural epistemology of contagion? This essay aims to address these questions by shedding light onto the implicit and understudied translation-contagion link. It offers the first comparative analysis of its kind covering three centuries (nineteenth century-present), two languages (French and Italian), and four contagious diseases (plague, smallpox, Ebola and Aids). It provides an interdisciplinary model to approach the study of literature and epidemiology in a synergic, non-exclusive way, one that is based on the double mobilisation, or 'entanglement' (Whitehead et al., 2016), of literary and medical knowledge. 

scholarly journals Comparative analysis of single cell lung atlas of bat, cat, tiger and pangolin

2021 ◽  
Author(s):  
Xiran Wang ◽  
Zhihua Ou ◽  
Peiwen Ding ◽  
Chengcheng Sun ◽  
Daxi Wang ◽  
...  
Keyword(s):  
Immune System ◽  
Comparative Analysis ◽  
Single Cell ◽  
Animal Species ◽  
Respiratory Viruses ◽  
Virus Infections ◽  
Species Comparison ◽  
Transcriptomic Data ◽  
Horseshoe Bat ◽  
Horseshoe Bats

Horseshoe bats (Rhinolophus sinicus) might help maintain coronaviruses severely affecting human health, such as SARS-CoV and SARS-CoV-2. It has long been suggested that bats may be more tolerant of viral infection than other mammals due to their unique immune system, but the exact mechanism remains to be fully explored. During the COVID-19 pandemic, multiple animal species were diseased by SARS-CoV-2 infection, especially in the respiratory system. Herein, single-cell transcriptomic data of the lungs of a horseshoe bat, a cat, a tiger, and a pangolin were generated. The receptor distribution of twenty-eight respiratory viruses belonging to fourteen viral families were characterized for the four species. Comparison on the immune-related transcripts further revealed limited cytokine activations in bats, which might explain the reason why bats experienced only mild diseases or even no symptoms upon virus infection. Our findings might increase our understanding of the immune background of horseshoe bats and their insensitivity to virus infections.

scholarly journals Cancer vaccines: a newer front of immunotherapy

2018 ◽  
Vol 7 (12) ◽  
pp. 5214
Author(s):  
Sonia Puri ◽  
Naveen Krishan Goel ◽  
Veenal Chadha ◽  
Praizy Bhandari
Keyword(s):  
Immune System ◽  
Cancer Treatment ◽  
Cancer Cells ◽  
Cancer Vaccines ◽  
Biological Response ◽  
Communicable Diseases ◽  
The Body ◽  
Therapeutic Vaccines ◽  
Non Communicable Diseases ◽  
Cervical Cancer Vaccine

Vaccines have been used as a promising instrument over the years to combat the dreadful communicable diseases. But now owing to epidemiological transition as the burden of non-communicable diseases has increased, efforts are now being made globally to use this weapon for non-communicable diseases like cancer. Cancer vaccines belong to a class of substances known as “biological response modifiers”. These work by stimulating or restoring the immune system’s ability to fight infections and disease. There are two broad types of cancer vaccines: Preventive (or prophylactic) vaccines and Treatment or therapeutic vaccines. Cancer treatment vaccines are made up of cancer cells, parts of cells or pure antigens. Sometimes a patient’s own immune cells are removed and exposed to these substances in the lab to create the vaccine.  Cancer treatment vaccines differ from the vaccines that work against viruses. These vaccines try to get the immune system to mount an attack against cancer cells in the body. Instead of preventing disease, they are meant to get the immune system to attack a disease that already exists. Preventive vaccines are intended to prevent cancer from developing in healthy people.  And in fact, many evidence-based studies have proven the decrease in morbidity and mortality in various cancers by usage of some of the vaccines like cervical cancer vaccine etc. The biggest challenges currently facing preventive anti-cancer vaccines are clinical, social, and economic in nature.  This article is an effort to   highlight the advances in various cancer vaccines, so done, to use them on preventive and therapeutic front.

scholarly journals Vaccination status of medical students and faculty members

2021 ◽  
Vol 13 (8) ◽  
pp. e8277
Author(s):  
Aléxia Alves Cabral ◽  
Cecília Pereira Silva ◽  
Fernanda del Carlo Cândido ◽  
Igor Dutra Braz ◽  
Izabella dos Santos Gomes ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Medical Students ◽  
Quantitative Research ◽  
Risk Group ◽  
Action Plan ◽  
Health Sector ◽  
High Risk Group ◽  
Vaccination Status ◽  
Faculty Members ◽  
Contagious Diseases

Objectives: To analyze the student's and professor's vaccinal situation of a medical course. Methods: It is a transversal and quantitative research, done in 2019, which aimed to identify if preconized vaccines of Programa Nacional de Imunização (PNI) were administered or not. The data was obtained through a questionnaire applied to professors and students from the 1st to the 12th period, under CAAE 08246918.1.0000.5237. Posteriorly, it was done an inferential and comparative analysis with literature and vaccinal data from previous research done in 2014, at the same institution, that evaluated vaccination for hepatitis B, dT, varicella, influenza, and HPV. Results: Despite the rise in vaccination of students from 2014 to 2019, most of PNI coverage goals were not reached in 2019. As a result, it is necessary to maintain the incentives for vaccination in the health sector since the sample is constituted of a high-risk group of infectious contagious diseases. Conclusion: The implementation of an action plan for the exigence of the updated vaccinal chart as a prerequisite for registration of medical students must be considered. It is expected that it would reinforce the relevance of vaccination for diseases that are preventable through immunization.

scholarly journals Comparative analysis of the Pocillopora damicornis genome highlights role of immune system in coral evolution

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
R. Cunning ◽  
R. A. Bay ◽  
P. Gillette ◽  
A. C. Baker ◽  
N. Traylor-Knowles
Keyword(s):  
Immune System ◽  
Comparative Analysis ◽  
Pocillopora Damicornis

scholarly journals Lactobacillus buchneri Genotyping on the Basis of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Locus Diversity

2013 ◽  
Vol 80 (3) ◽  
pp. 994-1001 ◽  
Author(s):  
Alexandra E. Briner ◽  
Rodolphe Barrangou
Keyword(s):  
Immune System ◽  
Comparative Analysis ◽  
Common Origin ◽  
Type Ii ◽  
Crispr Locus ◽  
Content Type ◽  
Lactobacillus Buchneri ◽  
Protospacer Adjacent Motif ◽  
Associated Sequences ◽  
Short Palindromic Repeat

ABSTRACTClustered regularly interspaced short palindromic repeats (CRISPR) in combination with associated sequences (cas) constitute the CRISPR-Cas immune system, which uptakes DNA from invasive genetic elements as novel “spacers” that provide a genetic record of immunization events. We investigated the potential of CRISPR-based genotyping ofLactobacillus buchneri, a species relevant for commercial silage, bioethanol, and vegetable fermentations. Upon investigating the occurrence and diversity of CRISPR-Cas systems inLactobacillus buchnerigenomes, we observed a ubiquitous occurrence of CRISPR arrays containing a 36-nucleotide (nt) type II-A CRISPR locus adjacent to fourcasgenes, including the universalcas1andcas2genes and the type II signature genecas9. Comparative analysis of CRISPR spacer content in 26L. buchneripickle fermentation isolates associated with spoilage revealed 10 unique locus genotypes that contained between 9 and 29 variable spacers. We observed a set of conserved spacers at the ancestral end, reflecting a common origin, as well as leader-end polymorphisms, reflecting recent divergence. Some of these spacers showed perfect identity with phage sequences, and many spacers showed homology toLactobacillusplasmid sequences. Following a comparative analysis of sequences immediately flanking protospacers that matched CRISPR spacers, we identified a novel putative protospacer-adjacent motif (PAM), 5′-AAAA-3′. Overall, these findings suggest that type II-A CRISPR-Cas systems are valuable for genotyping ofL. buchneri.

scholarly journals Comparative Analysis And Criteria For Highlighting The Circumstances Of The Course Of Action In Pashto And Russian

2021 ◽  
Vol 03 (04) ◽  
pp. 194-200
Author(s):  
Eleonora Ilsurovna Zamaleeva ◽  
Keyword(s):  
Comparative Analysis ◽  
Mode Of Action ◽  
Russian Language ◽  
Parts Of Speech ◽  
Grammatical Categories ◽  
Course Of Action ◽  
Functional Features ◽  
The Russian Language ◽  
Selection Of

The article is devoted to the comparative, as well as the criteria for highlighting the circumstance of the mode of action in the Pashto language, approaches to the selection of the circumstance of the mode of action among other grammatical categories in Pashto and Russian. In terms of the functional features of adverbs, it is worth noting that an adverb always performs the function of a circumstance in a sentence. For example, the circumstances of time, place, degree, or mode of action in both Pashto and Russian. In the adverbialization characteristic of the Pashto language adverbs, it can be noted that this paragraph considers the process of the transition of adverbs to other parts of speech. In the Pashto language, as in the Russian language, the circumstance is divided into the following groups: place, time, degree, mode of action, and others.

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