scholarly journals Organo-Protective Effect of Moringa oleifera (Moringa) and Camellia sinensis (Green Tea) against Histopathological Damage in Monosodium Glutamate-induced Oxidative-Stressed Rats

Author(s):  
Ikechukwu E. Ezeagu ◽  
◽  
Moses B. Ayoola ◽  
Nonso C. Ejiofor ◽  
Peter Achukwu ◽  
...  
2015 ◽  
Vol 12 (24) ◽  
pp. 17-27
Author(s):  
Luana Taís Hartmann BACKES ◽  
Telma Elita BERTOLIN ◽  
Silvana Souza ROMAN ◽  
Janaine de Oliveira PAIVA ◽  
Vanusa MANFREDINI ◽  
...  

The use of medicinal plants is expressive because it’s beneficial effects, however the dosages some times are not adjusted. The study had for objective to investigate the toxicity of the green tea and the protective effect of vitamin C. Had been used 36 mice swiss, distributed in 6 groups (n=6): Control group with 1 ml/kg of saline solution 0.9%; Experimental group 1 with extract of Camellia sinensis in 0,5% concentration; Experimental group 2 with extract of Camellia sinensis in 10% concentration; Experimental group 3 with extract of Camellia sinensis in 0,5% concentration associate with vitamin C in 40mg/mL concentration; Experimental group 4 with extract of Camellia sinensis in 10% concentration associate with vitamin C in 40mg/mL concentration and Experimental group 5 with vitamin C solution in 40mg/mL concentration. The results had been significant for corporal weight and agencies (liver, kidneys, dull and brain) in the group of bigger concentration of green tea and in the groups where vitamin C was associated, allowing itself to suggest a light toxicity in the groups that had received these treatments.


2013 ◽  
Vol 2 (7) ◽  
Author(s):  
M. Negahdary ◽  
R. Chelongar ◽  
S. Papi ◽  
A. Noori ◽  
R. Rahimzadeh ◽  
...  

2019 ◽  
Vol 20 (7) ◽  
pp. 542-550 ◽  
Author(s):  
Nahla S. El-Shenawy ◽  
Reham Z. Hamza ◽  
Fawziah A. Al-Salmi ◽  
Rasha A. Al-Eisa

Background: Zinc oxide nanoparticles (ZnO NPs) are robustly used biomedicine. Moreover, no study has been conducted to explore the consequence of green synthesis of ZnO NPs with Camellia sinensis (green tea extract, GTE) on kidneys of rats treated with monosodium glutamate (MSG). Methods: Therefore, the objective of the research was designed to explore the possible defensive effect of GTE/ZnO NPs against MSG-induced renal stress investigated at redox and histopathological points. Results: The levels of urea and creatinine increased as the effect of a high dose of MSG, in addition, the myeloperoxidase and xanthine oxidase activates were elevated significantly with the high dose of MSG. The levels of non-enzymatic antioxidants (uric acid, glutathione, and thiol) were decreased sharply in MSG-treated rats as compared to the normal group. Conclusion: The data displayed that GTE/ZnO NPs reduced the effects of MSG significantly by reduction of the level peroxidation and enhancement intracellular antioxidant. These biochemical findings were supported by histopathology evaluation, which showed minor morphological changes in the kidneys of rats.


2019 ◽  
Vol 15 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Satheesh Babu Natarajan ◽  
Suriyakala Perumal Chandran ◽  
Sahar Husain Khan ◽  
Packiyaraj Natarajan ◽  
Karthiyaraj Rengarajan

Background: Tea (Camellia sinensis, Theaceae) is the second most consumed beverage in the world. Green tea is the least processed and thus contain rich antioxidant level, and believed to have most of the health benefits. </p><p> Methods: We commenced to search bibliographic collection of peer reviewed research articles and review articles to meet the objective of this study. </p><p> Results: From this study, we found that the tea beverage contains catechins are believed to have a wide range of health benefits which includes neuroprotective, anti-inflammatory, antiulcer, antiviral, antibacterial, and anti-parasitic effects. The four major catechin compounds of green tea are epigallocatechin (EGC), epicatechin (EC), epigallocatechin gallate (EGCG), and epicatechin gallate (ECG), of which EGCG is the major constituent and representing 50-80% of the total catechin content. And also contain xanthine derivatives such as caffeine, theophylline, and theobromine, and the glutamide derivative theanine. It also contains many nutritional components, such as vitamin E, vitamin C, fluoride, and potassium. We sum up the various green tea phytoconstituents, extraction methods, and its medicinal applications. </p><p> Conclusion: In this review article, we have summarized the pharmacological importance of green tea catechin which includes antioxidant potential, anti-inflammatory, antimicrobial, anticancer, antidiabetic and cosmetic application.


Author(s):  
Jéssica G. A. Melo ◽  
Jossaria P. Sousa ◽  
Ramon T. Firmino ◽  
Carolina C. Matins ◽  
Ana Flávia Granville‐Garcia ◽  
...  

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