scholarly journals The influence of a 3-week body mass reduction program on the metabolic parameters and free amino acid profiles in adult Polish people with obesity

2018 ◽  
Vol 27 (6) ◽  
pp. 749-757 ◽  
Author(s):  
Małgorzata Moszak ◽  
Agnieszka Klupczynska ◽  
Alina Kanikowska ◽  
Zenon Kokot ◽  
Agnieszka Zawada ◽  
...  
2020 ◽  
Author(s):  
Małgorzata Moszak ◽  
Agnieszka Zawada ◽  
Aldona Juchacz ◽  
Marian Grzymisławski ◽  
Paweł Bogdański

Abstract Background: Amaranth seed oil (ASO) and rapeseed oil (RSO) are representative functional food with glucose and cholesterol-lowering, antioxidant, and hepatoprotective properties. We aimed to determine whether compared to RSO, ASO supplementation can improve the weight loss and metabolic parameters when consumed as a part of a 3-week weight loss program.Methods: Eighty-one obese subjects (BMI > 30 kg/m 2 ) aged 25−70 years enrolled in a 3-week body mass reduction program based on calorie-restricted diet and physical activity. The participants were randomly administered 20 ml/d of ASO (AO group) or 20 ml/d of RSO (RO group), or were assigned to the control (C) group. Anthropometric and metabolic parameters were measured at baseline and at endpoint.Results: At the end of the study, significant ( P < 0.05) decrease in weight, BMI, WC (waist circumference), HC (hip circumference), FM (fat mass), LBM (lean body mass), VFM (visceral fat mass), and TBW% (total body water) were observed in all the studied groups. There were no significant improvements in clinical parameters in the C group, while reduction in fasting insulin ( P = 0.001 and P = 0.005) and HOMA-IR ( P = 0.02 and P = 0.03) were observed in the RO and AO groups. Compared to the RO group, we observed significant improvement in fasting glucose ( P = 0.03), total cholesterol ( P = 0.03), non-HDL cholesterol ( P = 0.01), TG/HDL ratio ( P = 0.03), LDL cholesterol ( P = 0.04), and triglycerides ( P = 0.000008) in the AO group.Conclusions: The 3-week body mass reduction intervention resulted in statistically significant reduction in weight, BMI, WC, HC, FM, and VFM in all the studied groups. The fasting insulin level and HOMA-IR improved in both AO and RO groups. In contrast to the RO group, positive changes in glucose and lipid levels were observed in the AO group. Compared to the AO and RO groups, subjects without oil supplementation did not show improvement in clinical parameters. Thus, edible oils may improve metabolic parameters during weight loss programs.


2019 ◽  
Vol 62 ◽  
pp. 103569 ◽  
Author(s):  
Wen Chaoyue ◽  
Li Fengna ◽  
Duan Yehui ◽  
Guo Qiuping ◽  
Wang Wenlong ◽  
...  

2017 ◽  
Vol 313 (4) ◽  
pp. R487-R495 ◽  
Author(s):  
Desy Salvadego ◽  
Alessandro Sartorio ◽  
Fiorenza Agosti ◽  
Gabriella Tringali ◽  
Alessandra Patrizi ◽  
...  

In obesity, the increased O2 cost of breathing negatively affects the O2 cost of exercise and exercise tolerance. The purpose of the study was to determine whether, in obese adolescents, the addition of respiratory muscle endurance training (RMET) (isocapnic hyperpnea) to a standard body mass reduction program decreases the O2 cost of exercise and perceived exertion. Nine male obese adolescents [16.0 ± 1.4 yr ( x ± SD), body mass 114.4 ± 22.3 kg] underwent 3 wk of RMET (5 days/week) in addition to a standard body mass reduction program. Eight age- and sex-matched obese adolescents underwent only the standard program (CTRL). Before and after interventions, patients performed on a cycle ergometer: incremental exercise; 12-min exercises at a constant work rate (CWR) of 65% and 120% at the gas exchange threshold (GET) determined before the intervention. Breath-by-breath pulmonary ventilation (V̇e) and O2 uptake (V̇o2), heart rate (HR), and ratings of perceived exertion for dyspnea/respiratory discomfort (RPER) and leg effort (RPEL) were determined. Body mass decreased (by ~3.0 kg) after both RMET ( P = 0.003) and CTRL ( P = 0.002). Peak V̇o2 was not affected by both interventions. Peak work rate was slightly, but significantly ( P = 0.04), greater after RMET but not after CTRL. During CWR < GET, no changes were observed after both interventions. During CWR > GET, the O2 cost of cycling at the end of exercise ( P = 0.02), the slope of V̇o2 vs. time (3–12 min) ( P = 0.01), RPER ( P = 0.01), and RPEL ( P = 0.01) decreased following RMET, but not following CTRL. HR decreased after both RMET ( P = 0.02) and CTRL ( P = 0.03), whereas V̇e did not change. In obese adolescents RMET, superimposed on a standard body mass reduction program, lowered the O2 cost of cycling and perceived exertion during constant heavy-intensity exercise.


2020 ◽  
Author(s):  
Małgorzata Moszak ◽  
Agnieszka Zawada ◽  
Aldona Juchacz ◽  
Marian Grzymisławski ◽  
Paweł Bogdański

Abstract Background: Amaranth seed oil (ASO) and rapeseed oil (RSO) are functional foods that display antioxidant and hepatoprotective properties. These oils are also known to lower glucose and cholesterol levels. The current study compared the effects exerted by RSO and ASO on weight loss and metabolic parameters during a 3-week body mass reduction program. Methods: Eighty-one obese subjects (BMI > 30 kg/m2), aged 25-70 years, were enrolled in a 3-week body mass reduction program based on a calorie-restricted diet and physical activity. Participants were randomly categorized into an AO group (administered 20 mL/d of ASO), a RO group (administered 20 mL/d of RSO), and a C group (control; untreated). Anthropometric and metabolic parameters were measured at baseline and endpoint. Results: Significant decreases in weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), fat mass (FM), lean body mass (LBM), visceral fat mass (VFM), and total body water (TBW%) were observed in all groups (P < 0.05). No significant improvements were observed in the clinical parameters of group C. Fasting insulin (Δ -5.9, and Δ -5.7) and homeostatic model assessment of insulin resistance (HOMA-IR) (Δ -1.1 and Δ -0.5) were decreased in both RO and AO groups, respectively. Fasting glucose (Δ -8.5; P = 0.034), total cholesterol (Δ -14.6; P = 0.032), non-HDL cholesterol (Δ 15.9; P = 0.010), TG/HDL ratio (Δ -0.6; P = 0.032), LDL cholesterol (Δ -12.3; P = 0.042), and triglycerides (Δ -6.5; P = 0.000) were significantly improved in the AO group, compared to the RO group. Conclusions: The 3-week body mass reduction intervention caused a significant reduction in the weight, BMI, WC, HC, FM, and VFM of all groups. Except for HOMA-IR, there were no statistical differences between the clinical parameters of all groups. However, a trend toward improved insulin levels and HDL% was noticeable in AO and RO. Therapies involving edible oils with high nutritional value, such as RSO and ASO, show potential for improving metabolic measurements during body mass reduction programs. Thus, obese patients undertaking weight reduction programs may benefit from RSO and ASO supplementation.


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