scholarly journals Polymorphisms and association of FAT1 gene with wool quality traits in Chinese Merino sheep

2020 ◽  
Vol 65 (No. 1) ◽  
pp. 31-39
Author(s):  
Guang-Wei Ma ◽  
Xin You ◽  
Hua Yang ◽  
Xiao-Hong Yan ◽  
Fang Mou ◽  
...  
Keyword(s):  
Planar Cell Polarity ◽  
Fibre Diameter ◽  
Fibre Length ◽  
Wool Fibre ◽  
Pcr Analysis ◽  
Quality Trait ◽  
Quality Traits ◽  
Exon 2 ◽  
Merino Sheep ◽  
Wool Quality

FAT atypical cadherin 1 (FAT1) is a member of the atypical cadherin superfamily and is involved in the planar cell polarity signalling pathway which regulates hair follicle morphogenesis, cycling, and orientation. The purpose of this study was to investigate the sheep FAT1 gene expression, polymorphisms and its association with wool quality traits in Chinese Merino sheep. Quantitative real-time PCR analysis showed that the FAT1 mRNA was differentially expressed in the adult skin of Chinese Merino and Kazak sheep. Seven SNPs (termed SNPs 1–7) were identified in exon 2 of sheep FAT1 gene by Sanger sequencing. SNPs 2 and 7 (novel SNPs) were significantly associated with wool crimp (P < 0.05). SNPs 4 and 5 (rs161528993 and rs161528992) were significantly associated with wool fibre length (P < 0.05). SNP 7 was highly significantly associated with average wool fibre diameter (P < 0.01). Similarly, FAT1 haplotypes were significantly associated with wool crimp (P < 0.05), and the haplotypes H1–H3 and H5 were significantly associated with higher wool crimp (P < 0.05). Bioinformatics analysis showed that the wool quality trait-associated SNPs (SNPs 2, 4, 5 and 7) might affect the pre-mRNA splicing by creating or abolishing the binding sites for serine/arginine-rich proteins, and in addition, SNPs 2 and 4 might alter the FAT1 mRNA secondary structure. Our results suggest that FAT1 influences wool quality traits and its SNPs 2, 4, 5 and 7 might be useful markers for marker-assisted selection and sheep breeding.

Genetic parameters for visually assessed traits and their relationships to wool production and liveweight in Australian Merino sheep

2009 ◽  
Vol 49 (1) ◽  
pp. 32 ◽  
Author(s):  
S. I. Mortimer ◽  
D. L. Robinson ◽  
K. D. Atkins ◽  
F. D. Brien ◽  
A. A. Swan ◽  
...  
Keyword(s):  
Coefficient Of Variation ◽  
Genetic Correlations ◽  
Fibre Diameter ◽  
Quality Traits ◽  
Production Traits ◽  
Merino Sheep ◽  
Wool Production ◽  
Breeding Objectives ◽  
Wool Quality ◽  
Staple Length

Heritability was estimated for a range of visually assessed traits recorded on Merino sheep, together with the phenotypic and genetic correlations among the visually assessed traits and correlations of the visually assessed traits with measured wool production traits and liveweight. Data were derived from four research resource flocks, with a range of 12 958 to 57 128 records from animals with 478 to 1491 sires for the various traits. The estimates of heritability were high for the wool quality traits of handle, wool character and wool colour (0.33–0.34) and the conformation traits of face cover, neck wrinkle and body wrinkle (0.42–0.45), moderate for front leg structure (0.18) and low for back leg structure (0.13). Fleece rot score had low heritability (0.14), while classer grade was moderately heritable (0.20). Estimates of genetic correlations among the visually assessed wool quality traits were low to moderate in size and positive (0.17–0.47). Genetic correlation estimates among the assessed conformation traits were generally very low, except for the genetic correlations between scores for neck and body wrinkle (0.92 ± 0.01) and front and back leg structure (0.31 ± 0.09). Fleece rot score had low positive genetic correlations with neck and body wrinkle scores (0.18 ± 0.05 and 0.15 ± 0.05, respectively) and classer grade (0.26 ± 0.06). Classer grade was slightly positively correlated with the wool quality traits (0.17–0.45) and leg structure traits (0.21–0.25). The genetic correlations among the visually assessed traits were generally neutral to favourable. The visually assessed wool quality traits had low to moderate favourable genetic correlations with mean and coefficient of variation of fibre diameter (0.19 –0.47), but negative correlations with clean wool yield (–0.26 to –0.37). Face cover was unfavourably correlated with staple length (–0.27 ± 0.04) and liveweight (–0.23 ± 0.02). Neck and body wrinkle scores were genetically associated with higher greasy (0.33–0.39) and clean fleece weights (0.19–0.22), greater coefficient of variation of fibre diameter (0.24–0.26) and fibre curvature (0.27–0.28), but with reduced yield (–0.26 to –0.28) and staple length (–0.34 to –0.41). Fleece rot score was genetically correlated with clean fleece weight (0.26 ± 0.05) and coefficient of variation of fibre diameter (0.27 ± 0.04). Classer grade was favourably correlated with greasy and clean fleece weights (–0.41 to –0.43), staple length (–0.29 ± 0.04), liveweight (–0.36 ± 0.03) and coefficient of variation of fibre diameter (0.27 ± 0.03). Most genetic correlations between the visually assessed traits and the measured production traits and liveweight were close to zero and less than 0.2 in magnitude. This study provides accurate values for the parameter matrix required to incorporate visually assessed traits into breeding objectives and the genetic evaluation programs used in the Australian sheep industry, allowing the development of breeding objectives and indexes that optimally combine visually assessed performance and measured production in Merino sheep.

Effects of site of assessment and variation in wool quality traits on the tactile assessment of textural greasy wool handle

2014 ◽  
Vol 54 (10) ◽  
pp. 1665 ◽  
Author(s):  
J. W. V. Preston ◽  
S. Hatcher ◽  
B. A. McGregor
Keyword(s):  
Fibre Diameter ◽  
Quality Traits ◽  
Merino Sheep ◽  
Diameter Fibre ◽  
Wool Quality ◽  
A Site ◽  
Staple Length

Variation in textural greasy wool handle across the fleece of Merino sheep was explored. Results demonstrate that there were significant differences across nine sites on the fleece. The inclusion of the covariates fibre diameter, fibre diameter co-efficient of variation, staple length, dust penetration, staple structure, greasy wool colour and resistance to compression, helped to explain some of the variation in textural greasy wool handle between sites such that site of assessment was no longer a significant factor (P = 0.065). However, in practice, those involved with clip preparation or sheep selection based on textural greasy wool handle assessment are unlikely to have these measurements available. The results highlight the importance of nominating a site of assessment when recording textural greasy wool handle.

Environmental influence on Merino sheep wool quality through the lens of seasonal variations in fibre diameter

2020 ◽  
Vol 181 ◽  
pp. 104248
Author(s):  
Ezequiel Bernardo Gonzalez ◽  
Diego Mariano Sacchero ◽  
Marcos Horacio Easdale
Keyword(s):  
Seasonal Variations ◽  
Environmental Influence ◽  
Fibre Diameter ◽  
Merino Sheep ◽  
Wool Quality ◽  
Sheep Wool

Transient treatment of pregnant Merino ewes with modulators of cortisol biosynthesis coinciding with primary wool follicle initiation alters lifetime wool growth

2013 ◽  
Vol 53 (10) ◽  
pp. 1101 ◽  
Author(s):  
M. L. McDowall ◽  
N. S. Watson-Haigh ◽  
N. M. Edwards ◽  
H. N. Kadarmideen ◽  
G. S. Nattrass ◽  
...  
Keyword(s):  
Transforming Growth Factor ◽  
Fibre Diameter ◽  
Fibre Length ◽  
Gene Families ◽  
Transforming Growth Factor Β ◽  
In Utero ◽  
Skin Development ◽  
Merino Sheep ◽  
Wool Follicle ◽  
Critical Phases

The economically important characteristics of the adult fleece of Merino sheep, such as increases in clean fleece weight, fibre length, fibre diameter and crimp characteristics are determined during critical phases of fetal development of the skin and its appendages. Genetics plays a major role in the development of traits, but the maternal uterine environment could also influence development. Treatment of pregnant ewes with cortisol and its analogues has previously been shown to produce changes in wool follicle morphology. The aim of this study was to determine the effect of transient manipulation of maternal cortisol status during critical phases of wool follicle initiation and development in utero. From Days 55–65 post-conception, singleton-bearing Merino ewes were treated with metyrapone (cortisol inhibitor) or betamethasone (cortisol analogue). Lambs exposed to metyrapone in utero were born with hairier birthcoats than the control or betamethasone treatment groups (P < 0.05), displayed a 10% increase in staple length and a reduction in crimp frequency for the first three shearings (P < 0.05). Co-expression network analysis of microarray data revealed up-regulation of members of the transforming growth factor-β and chemokine receptor superfamilies, gene families known to influence hair and skin development. These experiments demonstrate that presumptive transient manipulation of maternal cortisol status coinciding with the initiation of fetal wool follicle development results in long-term alteration in fleece characteristics, namely fibre length and fibre crimp frequency. These results indicate it is possible to alter the lifetime wool production of Merino sheep with therapeutics targeted to gene expression during key windows of development in utero.

An evaluation of Merino wool quality: III. The prediction of uniformity of fleece characters from fleece and skin characters of the birthcoat

1971 ◽  
Vol 76 (2) ◽  
pp. 211-215 ◽  
Author(s):  
J. R. Gallagher
Keyword(s):  
Fibre Diameter ◽  
Fibre Length ◽  
Objective Measurement ◽  
Merino Wool ◽  
Wool Quality

SUMMARYFibres of anomalous length or diameter are undesirable in the Merino, a breed noted for uniformity of fleece characters. Previous studies which have aimed at estimating adult fleece quality have been based on visual appraisal of the birthcoat. This study was undertaken to test the prediction of uniformity of fibre length at 10½ months and fibre diameter at 15 months from the objective measurement of birthcoat fleece and skin follicle characters.The results indicated that fibre length uniformity at 10½ months cannot be predicted from measurement of fleece or skin characters at birth. It was found that fibre diameter uniformity at 15 months can be predicted from objective measurement of mean fibre diameter of the birthcoat but not by visual appraisal.

Effect of light and temperature on wool growth

1978 ◽  
Vol 90 (2) ◽  
pp. 329-334 ◽  
Author(s):  
A. A. Elsherbiny ◽  
H. A. Eloksh ◽  
A. S. Elsheikh ◽  
M. H. Khalil
Keyword(s):  
Seasonal Changes ◽  
Seasonal Pattern ◽  
Fibre Diameter ◽  
Fibre Length ◽  
Atmospheric Temperature ◽  
Wool Fibre ◽  
Wool Growth ◽  
Dim Light ◽  
Normal Light ◽  
Winter Time

SummaryWool samples were collected from 39 rams representing five breed groups of sheep: Merino (M), Ossimi (0), and the crosses between them, viz. ¾ Ossimi–¾ Merino (¾ O), ½ Ossimi–½ Merino (½ O) and ½ Ossimi–¾ Merino (¼ O) maintained at Sakha Experiment Station, Kafrelsheikh, Egypt, with the objectives of detecting the effect of the seasonal changes in normal light rhythm and temperature on wool fibre length and diameter. Animals were divided into two light treatments groups, the first consisting of four animals from each breed kept under continuous dim light conditions throughout the year and the second of three animals from Ossimi and four from each breed group kept inside an open pen free to sunlight and shade zones under daylight rhythm throughout the year. It was found that fibre length as well as fibre diameter in normal light exceeded that in dim light except in winter time. Breed groups showed different responses to the absence of light especially the Ossimi and the ¾ O whose fibre lengths were most affected. The breed groups had larger fibre diameters in normal light than in dim light except Merino and ¼ O. Seasonal changes in temperature had a highly significant effect on fibre length but not on fibre diameter. Higher temperature coincided with lower increases in fibre length. Season to season variation in wool growth seemed to suggest that the number of light hours per day and atmospheric temperature counteracted each other resulting in a non-significant seasonal pattern.

Predicted responses in Merino sheep from selection combining visually assessed and measured traits

2010 ◽  
Vol 50 (10) ◽  
pp. 976 ◽  
Author(s):  
S. I. Mortimer ◽  
K. D. Atkins ◽  
S. J. Semple ◽  
N. M. Fogarty
Keyword(s):  
Fibre Diameter ◽  
Selection Combining ◽  
Breeding Programs ◽  
Dual Purpose ◽  
Merino Sheep ◽  
Merino Wool ◽  
Wool Quality ◽  
Staple Strength ◽  
Fleece Weight ◽  
Australian Merino

Visually assessed traits for wool quality and ease of management are important to Merino sheep breeders and need to be considered in breeding programs. The present study reports on the predicted correlated responses in visual traits from selection using a range of standard MERINOSELECT™ indices available for use in Australian Merino breeding programs. The effect of including a visual trait in the index is also reported. The visual scored traits were classer grade, wool quality (handle, character and colour), conformation (neck and body wrinkle, front and back leg structure) and fleece rot. The indices covered a range of micron premiums of varying emphasis on increasing fleece weight and reducing fibre diameter. The indices were for Merino wool enterprises (Merino 14%, Merino 7% and Merino 3.5%) and Merino dual purpose wool and meat enterprises (Dual Purpose 7% and Dual Purpose 3.5%). The breeding objectives for the indices included fleece weight, fibre diameter, coefficient of variation of fibre diameter, staple strength, bodyweight and reproduction. Selection over 10 years using the standard MERINOSELECT™ indices is predicted to result in a small correlated improvement in the wool quality traits and classer grade, with a slight deterioration in fleece rot score. The improvement in wool handle, character and colour are greater with those indices that have a greater emphasis on reducing fibre diameter than with those increasing fleece weight. Indices with more emphasis on increased fleece weight than on reduced fibre diameter are predicted to result in small increases in neck and body wrinkle scores and a slight deterioration in wool colour. Inclusion of classer grade, handle, character or colour provided slight extra gains in fleece weight for indices that emphasised reduced fibre diameter through increased accuracy of selection.

Environmental responsiveness of fibre diameter in grazing fine wool Merino sheep

2005 ◽  
Vol 56 (7) ◽  
pp. 673 ◽  
Author(s):  
D. J. Brown ◽  
B. J. Crook
Keyword(s):  
Seasonal Variation ◽  
Fibre Diameter ◽  
Fibre Length ◽  
Skin Thickness ◽  
Merino Sheep ◽  
Length Growth ◽  
Environmental Responsiveness ◽  
Diameter Fibre ◽  
Staple Strength ◽  
Profile Characteristics

Fibre diameter, fibre length, and the ratio of fibre length growth to mean fibre diameter (L/D), fibre diameter profile characteristics, and staple strength were examined in 16 fine wool Merino wethers in a 12-month field experiment. Variations in fibre diameter, fibre length, and L/D were shown to be associated with fibre diameter profile characteristics and staple strength. At constant fibre diameter, L/D was significantly positively related to variation in fibre diameter along the staple. A positive correlation between seasonal variation in L/D and variation in diameter between fibres was also observed. Staple length was significantly positively correlated with along-staple variation in fibre diameter and negatively correlated with variation in fibre diameter among fibres. Among-fibre variation in fibre diameter was not significantly correlated with along-staple variation in fibre diameter. Seasonal variation in fibre length growth, fibre diameter, and the ratio of length to diameter throughout the year was associated with increased variation in fibre diameter along the fibre diameter profile and reduced staple strength in grazing sheep. Seasonal variation in fibre diameter was mostly related to mean fibre diameter, L/D, and seasonal variation in fibre length growth rate. Changes in fibre diameter throughout the year were also related to seasonal changes in body weight, fat depth, and skin thickness.

Effects of shearing time and time of lambing on wool growth and processing characteristics

1984 ◽  
Vol 24 (126) ◽  
pp. 337 ◽  
Author(s):  
GW Arnold ◽  
AJ Charlick ◽  
JR Eley
Keyword(s):  
Growth Rate ◽  
Seasonal Pattern ◽  
Fibre Diameter ◽  
Fibre Length ◽  
Lower Percentage ◽  
Dominant Factor ◽  
Lower Yield ◽  
Merino Sheep ◽  
Wool Growth ◽  
Fleece Weight

Wool growth rate, seasonal pattern of fibre diameter, clean fleece weight, quality and the processing characteristics of wool were measured on medium-wool Merino sheep shorn in March (autumn) or October (spring) coupled with March or June lambing. These four management systems were compared under two nutritional regimes in the medium rainfall area of Western Australia. The sheep grazed annual pastures only, or had lupin grain and stubble during summer in addition to the pasture. The study ran for two shearing periods. Time of shearing was the dominant factor. Sheep shorn in March produced 14% more clean wool and fewer tender fleeces than sheep shorn in October. The autumn wool had a lower yield, higher fibre diameter and when processed had a higher card loss, lower percentage noil and lower top and noil yield. However, mean fibre length in the top was substantially higher and the variation in fibre length lower. Vegetable matter was higher in autumn shorn wools. There were some interacting effects of lambing time and type of feed regime. Sheep fed lupins had lower yielding wool but this effect was more pronounced in June lambings and was reflected in differences in top and noil yield. From measurements of wool growth rate, it was found that the extra wool was produced in autumn after shearing, due possibly to stimulated appetite that cannot occur after spring shearing because the sheep are too fat.

Some properties of the wool from copper-starved Merino sheep

1949 ◽  
Vol 39 (3) ◽  
pp. 265-273 ◽  
Author(s):  
R. C. Palmer
Keyword(s):  
Tensile Strength ◽  
Amino Acid ◽  
Fibre Diameter ◽  
Fibre Length ◽  
South Australia ◽  
Fibre Strength ◽  
Research Association ◽  
Merino Sheep ◽  
Special Skill ◽  
The Mean

The mean fibre length, mean fibre diameter, mean fibre crimp ratio (i.e. ratio of length of the fibre under 2·5 mg. load to its length stretched), and a quantity approximately proportional to the ultimate tensile fibre strength, have been measured for twenty-five skirted Merino fleeces clipped from sheep that had been grazed at Robe (South Australia) on copperdeficient land and fed by mouth with amounts of copper varying from zero to 100 mg./day. Sulphur analyses and qualitative amino-acid analyses were carried out on some of the fleeces. The fleeces were processed one by one on the worsted system into yarn. The results show an increase in fibre diameter, an increase in ultimate tensile strength and an improvement in behaviour in processing with increasing dietary supplement of copper.A contribution to these experiments through special skill or knowledge has been made by almost everyone on the staff at Torridon, and especially by the late W. L. Semple, J. G. Martindale and H. Beevers. Thanks are due to Messrs Isaac Holden and Sons Ltd. for their generous co-operation in carrying out part of the work at their mill and to Mr A. Prescott, Mr F. Sharp and Mr G. W. Owen of the Wool Control, and Mr F. R. Emmett of Messrs Laycock, Son and Co. Ltd., for their assistance in judging tops. The author would like to thank Mr B. H. Wilsdon, the Director of Research, for suggestions and encouragement during this work, and the Council of the Wool Industries Research Association for permission to publish this paper.

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