scholarly journals Synthesis, Characterization and Crystal Structures of Zinc(II) and Cobalt(III) Complexes Derived from Tridentate NNO- and NON- Schiff Bases with Antibacterial Activities

2021 ◽  
Vol 68 (3) ◽  
pp. 700-708
Author(s):  
Heng-Yu Qian
Keyword(s):  
Antibacterial Activities ◽  
Bacterial Strains ◽  
X Ray Diffraction ◽  
X Ray ◽  
E Coli ◽  
Mtt Method ◽  
Trigonal Bipyramidal ◽  
Mononuclear Cobalt ◽  
Elemental Analyses ◽  
Distorted Trigonal Bipyramidal Coordination

Two new polynuclear zinc complexes [Zn2Br2(L1)2] (1) and [Zn(μ1,5-dca)L2]n (2), and two new mononuclear cobalt(III) complexes [CoL1N3(Brsal)] (3) and [CoL2(HL2)] (4), where L1 = 5-bromo-2-(((2-dimethylamino)ethyl)imino)methyl)phenolate, L2 = 5-bromo-2-(((2-hydroxyethyl)imino)methyl)phenolate, dca = dicyanoamide, Brsal = 5-bromo-2-formylphenolate, have been synthesized and characterized. The complexes were characterized by elemental analyses, IR, UVVis spectra, molar conductivity, and single crystal X-ray diffraction. X-ray analysis indicates that the Zn atoms in complex 1 are in distorted square pyramidal coordination, the Zn atoms in complex 2 are in distorted trigonal bipyramidal coordination, and the Co atoms in complexes 3 and 4 are in octahedral coordination. The molecules of the complexes are stacked through π···π interactions and hydrogen bonds. The complexes were assayed for antibacterial activities against three Gram-positive bacterial strains (B. subtilis, S. aureus, and St. faecalis) and three Gram-negative bacterial strains (E. coli, P. aeruginosa, and E. cloacae) by MTT method.

scholarly journals Syntheses, Crystal Structures, and Antibacterial Activity of New Tetranuclear Zinc(II) Complexes with Schiff Base Ligands

2021 ◽  
Vol 68 (3) ◽  
pp. 638-644
Author(s):  
Heng-Yu Qian
Keyword(s):  
Antibacterial Activities ◽  
Bacterial Strains ◽  
X Ray Diffraction ◽  
X Ray ◽  
E Coli ◽  
Mtt Method ◽  
Trigonal Bipyramidal ◽  
Vis Spectroscopy ◽  
Crystal Structural ◽  
L1 And L2

Two new tetranuclear zinc(II) complexes, [Zn4(L1)2(μ2-η1:η1-CH3COO)4(μ1,1-N3)2] (1) and [Zn4(L2)4(CH3CH2OH) (H2O)] (2), where L1 and L2 are the deprotonated forms of 4-fluoro-2-((pyridin-2-ylmethylimino)methyl)phenol (HL1) and 4-fluoro-2-((2-(hydroxymethyl)phenylimino)methyl)phenol (H2L2), have been synthesized and characterized by elemental analysis, IR and UV-vis spectroscopy, and single crystal X-ray diffraction. X-ray crystal structural study indicated that the distances between the adjacent Zn atoms are 3.160(1)–3.353(1) Å in 1 and 3.005(1)–3.168(1) Å in 2. All zinc atoms in 1 are pentacoordinated in trigonal bipyramidal geometry, and those in 2 are in square pyramidal and octahedral geometry. The complexes and the Schiff bases were assayed for antibacterial activities against three Gram-positive bacterial strains (B. subtilis, S. aureus, and St. faecalis) and three Gram-negative bacterial strains (E. coli, P. aeruginosa, and E. cloacae) by MTT method.

Effect of Ce3+ Ions Doped NiFe2O4 Magnetic Nanoparticles on Photocatalytic Degradation of Rhodamine B and Antibacterial Activities

2021 ◽  
Vol 21 (11) ◽  
pp. 5784-5793
Author(s):  
K. Geetha ◽  
R. Udhayakumar
Keyword(s):  
Photocatalytic Degradation ◽  
Rhodamine B ◽  
Spinel Ferrite ◽  
Magnetic Hysteresis ◽  
Aloe Vera ◽  
Antibacterial Activities ◽  
X Ray Diffraction ◽  
X Ray ◽  
E Coli ◽  
Ferrite Structure

In this study, spinel NiCexFe2–XO4 (x = 0.0 - 0.5) nanoparticles (NPs) was synthesized by microwave combustion technique (MCT) utilizing the fuel of Aloe vera plant extract. The establishment of spinel cubic crystal structure was ensured by powder X-ray diffraction (PXRD) technique. The particles like nanostructured morphology were confirmed by high-resolution scanning electron microscope (HRSEM). Energy dispersive X-ray (EDX) studies confirmed the formation of spinel ferrite structure and ensured that no other elements were present. Magnetic parameters such as remanant magnetisation (Mr), coercivity (He) and saturation magnetization (Ms) were calculated from the magnetic hysteresis (M-H) loops, which exhibited ferromagnetic behaviour. The photocatalytic behavior was investigated by visible light treatment for the photocatalytic degradation (PCD) of rhodamine B (Rh-B) dye and the sample NiCe0.3Fe1.7O4 exhibits higher PCD efficiency (93.88%) than other compositions. The antibacterial activities of gram-positive S. aureus, B. subtilis, gramnegative K. pneumonia and E. coli have been investigated using undoped and Ce3+ substituted NiFe2O4 NPs and observed higher activity, which indicated that, they can be used in the bio-medical applications.

scholarly journals Copper(II) and Zinc(II) Complexes Derived from N,N’-Bis(4-bromosalicylidene)propane-1,3-diamine: Syntheses, Crystal Structures and Antimicrobial Activity

2021 ◽  
Vol 68 (1) ◽  
pp. 102-108
Author(s):  
Yu-Mei Hao
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Candida Parapsilosis ◽  
Antibacterial Activities ◽  
X Ray Diffraction ◽  
Deprotonated Form ◽  
X Ray ◽  
Square Planar ◽  
Vis Spectroscopy ◽  
Elemental Analyses

A mononuclear copper(II) complex, [CuL] (1), and a phenolato-bridged trinuclear zinc(II) complex, [Zn3Cl2L2(DMF)2] (2), where L is the deprotonated form of N,N’-bis(4-bromosalicylidene)propane-1,3-diamine (H2L), have been prepared and characterized by elemental analyses, IR and UV-Vis spectroscopy, and single crystal X-ray diffraction. The Cu atom in complex 1 is in square planar coordination, while the terminal and central Zn atoms in complex 2 are in square pyramidal and octahedral coordination, respectively. The antibacterial activities of the complexes have been tested on the bacteria Staphylococcus aureus and Escherichia coli, and the yeast Candida parapsilosis.

scholarly journals Synthesis, Structures, and Antibacterial Activities of Hydrazone Compounds Derived from 4-Dimethylaminobenzohydrazide

2021 ◽  
Vol 68 (3) ◽  
pp. 567-574
Author(s):  
Guo-Xu He ◽  
Ling-Wei Xue
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Nmr Spectra ◽  
Antibacterial Activities ◽  
13C Nmr Spectra ◽  
X Ray Diffraction ◽  
X Ray ◽  
Mtt Method ◽  
Antibacterial Material ◽  
And Staphylococcus Aureus

A series of three new hydrazone compounds derived from the condensation reactions of 4-dimethylaminobenzohydrazide with 4-dimethylaminobenzaldehyde, 2-chloro-5-nitrobenzaldehyde and 3-methoxybenzaldehyde, respectively, were prepared. The compounds were characterized by elemental analysis, infrared and UV-vis spectra, HRMS, 1H NMR and 13C NMR spectra, and single crystal X-ray diffraction. Crystals of the compounds are stabilized by hydrogen bonds. The compounds were assayed for antibacterial (Bacillus subtilis, Escherichia coli, Pseudomonas fluorescence and Staphylococcus aureus) and antifungal (Aspergillus niger and Candida albicans) activities by MTT method. The results indicated that compound 2 is an effective antibacterial material.

scholarly journals Synthesis and Fluorescence Properties of a Structurally Characterized Hetero-Hexanuclear Zn(II)-La(III) Salamo-Like Coordination Compound Containing Auxiliary Ligands

Crystals ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 414
Author(s):  
Wen-Ting Guo ◽  
Ling-Zhi Liu ◽  
Meng Yu ◽  
Fei Wang ◽  
Jian-Chun Ma ◽  
...  
Keyword(s):  
Oxygen Atom ◽  
Single Crystal ◽  
Diffraction Analysis ◽  
Coordination Compound ◽  
Terephthalic Acid ◽  
Photophysical Property ◽  
X Ray Diffraction ◽  
X Ray ◽  
Trigonal Bipyramidal ◽  
Elemental Analyses

A hetero-hexanuclear Zn(II)-La(III) coordination compound, [{(ZnL)2La}2(bdc)2](NO3)2 (H2bdc = terephthalic acid) has been synthesized with a symmetric Salamo-like bisoxime, and characterized by elemental analyses, IR, UV-Vis, fluorescent spectroscopy, and single-crystal X-ray diffraction analysis. All of the Zn(II) ions are pentacoordinated by N2O2 donator atoms from the (L)2− unit and one oxygen atom from one terephthalate anion. The Zn(II) ions adopt trigonal bipyramidal geometries (τZn1 = 0.61, τZn2 = 0.56). The La(III) ions are decacoordinated in the Zn(II)-La(III) coordination compound and has a distorted bicapped square antiprism geometry. Meanwhile, the photophysical property of the Zn(II)-La(III) coordination compound was also measured and discussed.

scholarly journals Synthesis and Structure Features of Tetraphenylantimony 2,3-Difluoro- and 2,3,4,5,6-Pentafluorobenzoate

2020 ◽  
Vol 12 (4) ◽  
pp. 51-62
Author(s):  
A. Efremov ◽  
Keyword(s):  
Diffraction Analysis ◽  
X Ray Diffraction ◽  
Space Group ◽  
X Ray ◽  
Bond Lengths ◽  
Trigonal Bipyramidal ◽  
Cambridge Crystallographic Data Center ◽  
Redistribution Reaction ◽  
Distorted Trigonal Bipyramidal Coordination ◽  
Distorted Trigonal Bipyramidal

Tetraphenylantimony 2,3-difluorobenzoate (1) and tetraphenylantimony 2,3,4,5,6-pentafluorobenzoate (2) was obtained by the interaction of pentaphenylantimony with 2,3-difluorobenzoic and 2,3,4,5,6-pentafluorobenzoic acids in benzene with a yield of up to 98 %. The compounds were also synthesized by the ligand redistribution reaction between pentaphenylantimony and triphenylantimony dicarboxylates. The compounds have been identified by IR spectroscopy and X-ray diffraction analysis. According to the X-ray diffraction data, the antimony atoms in compounds 1 and 2 have a distorted trigonal-bipyramidal coordination with the oxygen atom in axial positions. X-ray diffraction analysis was performed on a D8 QUEST diffractometer (Bruker). The crystallographic parameters of the unit cell of the compounds: 1 space group Р1 ̅, а = 9.857(5), b = 10.154(7), c = 14.362(11) Å, α = 83.74(4)°, β = 82.59(3), γ = 68.34(2)°, V = 1321.9(16) Å3, ρcalc = 1.475 g/cm3, Z = 2; 2 space group Р21/с, а = 16.186(9), b = 8.771(6), c = 20.413(13) Å, α = 90.00°, β = 113.073(17), γ = 90.00°, V = 2666(3) Å3, ρcalc = 1.597 g/cm3, Z = 4. The OSbO axial angles are slightly different and amount to 177.90(5)º in 1 and 179.00(5)º in 2. The sums of the CSbC equatorial angles are 356.89(9)º (1), 355.85(7)º (2). The Sb–Ceq distances in compounds 1 and 2 are 2.116(2), 2.119(2), 2.118(2) and 2.1073(17), 2.1158(18), 2.1152(19) Å respectively, which are significantly shorter than the Sb–Сax bond lengths (2.169(2) and 2.1617(19) Å). The organization of molecules in the crystals of compounds is due to hydrogen bonds and CHπ-interactions of the aryl and carboxyl ligands. The main difference between structures 1 and 2 is the different Sb–O bond lengths (2.2864(18) and 2.3168(18) Å), which is due to an increase in the electronegativity of the carboxyl ligand in 2, caused by the presence of five electronegative fluorine atoms in the benzoate substituent. Complete tables of atom coordinates, bond lengths and valence angles are deposited at the Cambridge Crystallographic Data Center (No. 1980908 (1); 1977189 (2); [email protected]; http://www.ccdc.cam.ac.uk/data_request/cif).

The synthesis, and molecular and crystal structure of diphenyl(2-oxidonaphthylmethyl-iminoacetato)tin(IV)

1996 ◽  
Vol 74 (11) ◽  
pp. 2041-2047 ◽  
Author(s):  
Frank. E. Smith ◽  
Lian Ee Khoo ◽  
Ngoh Khang Goh ◽  
Rosemary C. Hynes ◽  
George Eng
Keyword(s):  
Crystal Structure ◽  
Elemental Analysis ◽  
Monoclinic Space Group ◽  
X Ray Diffraction ◽  
X Ray ◽  
H Nmr ◽  
Trigonal Bipyramidal ◽  
Intermolecular Contacts ◽  
Distorted Trigonal Bipyramidal Coordination ◽  
Distorted Trigonal Bipyramidal

The new diorganotin complex ((C6H5)2Sn(OC10H6CH=NCH2COO)) was prepared and characterized by 1H NMR, IR, elemental analysis, and a single crystal X-ray diffraction study. The crystals are monoclinic, space group P21/a with a = 16.9167(9) Å, b = 19.1276(16) Å, c = 26.538(2) Å, β = 100.534(6)°, V = 8442.5(11) Å3, Z = 16, and Dcalc = 1.574 Mg m−3. The final discrepancy factors are RF = 0.030, and RW = 0.021 for 6524 significant reflections. The tin atom has a distorted trigonal bipyramidal coordination, with no short intermolecular contacts. The two axial Sn—O bonds of 2.12 Å and 2.09 Å and the equatorial Sn—N bond of 2.14 Å are among the shortest found in related complexes. Key words: diorganotin(IV), bicycloazastannoxide, trigonal bipyramidal, antitumour.

scholarly journals Synthesis of Cefixime and Azithromycin Nanoparticles: An Attempt to Enhance Their Antimicrobial Activity and Dissolution Rate

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Farhat Ali Khan ◽  
Muhammad Zahoor ◽  
Noor Ul Islam ◽  
Rabia Hameed
Keyword(s):  
Structural Changes ◽  
Antibacterial Activities ◽  
Salmonella Typhi ◽  
Diffusion Method ◽  
X Ray Diffraction ◽  
Sem Images ◽  
X Ray ◽  
E Coli ◽  
Antisolvent Precipitation ◽  
C Decomposition

In this study cefixime and azithromycin nanoparticles were prepared by antisolvent precipitation with syringe pump (APSP) and evaporator precipitation nanosuspension (EPN) methods. The nanoparticles were characterized by XRD, FTIR, SEM, and TGA. X-ray diffraction pattern of cefixime samples showed the amorphous form, while azithromycin samples showed crystalline form. The FTIR spectra of parental drugs and synthesized nanoparticles have no major structural changes detected. The SEM images showed that nanoparticles of both drugs have submicron sized and nanosized particles. TGA analyses showed that above 30°C the decomposition of cefixime samples starts and their weight gradually decreases up to 600°C, while, in case of azithromycin, 30°C to 250°C, very small changes occur in weight; from above 250°C decomposition of the sample took place to a greater extent. The antibacterial activities of raw drugs and prepared samples of nanoparticles were determined againstStaphylococcus aureus,Shigella,E. coli, andSalmonella typhiby agar well diffusion method. Every time the nanoparticles samples showed better results than parental drugs. The dissolution rates of raw drugs and prepared nanoparticles were also determined. The results were always better for the synthesized nanoparticles than parental drug.

scholarly journals Cerium doped hydroxyapatite nanoparticles synthesized by coprecipitation method

2016 ◽  
Vol 81 (4) ◽  
pp. 433-446 ◽  
Author(s):  
Carmen Ciobanu ◽  
Cristina Popa ◽  
Daniela Predoi
Keyword(s):  
Electron Microscopy ◽  
Progressive Increase ◽  
Morphological Properties ◽  
Bacterial Strains ◽  
X Ray Diffraction ◽  
X Ray ◽  
E Coli ◽  
Transmission Electron ◽  
Ft Raman Spectroscopy ◽  
Xrd Studies

The present work reports a simple coprecipitation adapted method for the synthesis of stable Ce substituted to Ca hydroxyapatite (HAp) nanoparticles. The structural and morphological properties of Ce doped hydroxyapatite (Ce:HAp) were characterized by X-ray diffraction (XRD), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray analysis (EDAX). The optical properties of Ce doped hydroxyapatite were also investigated using Fourier Transform Infrared (FTIR) spectroscopy, FT Raman spectroscopy and photoluminescence analysis. The results of the XRD studies revealed the progressive increase in the a- and c-axes with increasing of Ce concentrations. In the FTIR studies of Ce:HAp powders a similar structure to hydroxyapatite was observed. IR and Raman wavenumbers and the peak strength of the bands associated to the P-O and O-H bonds decreases progressively with the increase of Ce concentration. All the emission maxima could be attributed to the 5d-4f transitions of Ce ions. The displacement of maximum emission bands with the increase of Cerium in the samples is in agreement with the results obtained by XRD studies. The Ce:HAp samples with xCe =0.03 and 0.05 exhibited significant antibacterial activity against Staphylococcus aureus ATCC 6538 and E. coli 714 bacterial strains compared to Ce:HAp samples with xCe =0 (pure HAp) and 0.01.

scholarly journals Zinc Complexes Derived from 5-Bromo-2-(((2-isopropylamino)ethyl)imino)methyl)phenol: Microwave-Assisted Synthesis, Characterization, Crystal Structures and Antibacterial Activities

2021 ◽  
Vol 68 (4) ◽  
pp. 921-929
Author(s):  
Wei-Guang Zhang ◽  
Ji-Hong Liang
Keyword(s):  
Antibacterial Activities ◽  
Molar Conductivity ◽  
Zinc Complexes ◽  
Microwave Assisted Synthesis ◽  
Tetrahedral Coordination ◽  
X Ray Diffraction ◽  
X Ray ◽  
Microwave Assisted ◽  
Elemental Analyses

Three new zinc complexes [Zn3L2(μ2-η1:η1-CH3COO)2(μ2-η2:η0-CH3COO)2] (1), [ZnCl2(HL)] (2) and [ZnBr2(HL)] (3), where L = 5-bromo-2-(((2-isopropylamino)ethyl)imino)methyl)phenolate, HL = 5-bromo-2-(((2-isopropylammonio) ethyl)imino)methyl)phenolate, have been synthesized under microwave irradiation. The complexes were characterized by elemental analyses, IR, UV-Vis spectra, molar conductivity, and single crystal X-ray diffraction. X-ray analysis revealed that the Zn atoms in complex 1 are in square pyramidal and octahedral coordination, and those in complexes 2 and 3 are in tetrahedral coordination. The molecules of the complexes are linked through hydrogen bonds and π···π interactions. In order to evaluate the biological activity of the complexes, in vitro antibacterial against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa was assayed.

Sign in / Sign up

Export Citation Format

Share Document