scholarly journals Precipitating Factors of Psoriasis in North Indian Population

2021 ◽  
Vol 9 (5) ◽  
pp. 280-285
Author(s):  
Dr. Kamlesh Kumar Bhaskar ◽  
◽  
Dr. Kavita Chawla ◽  
Dr. Beenu Beenu ◽  
Dr. Archana Mishra ◽  
...  

Aim: This study aims to study precipitating factors of psoriasis in the north Indian population.Material & Method:Two hundred twenty-eight psoriasis patients regardless of age, sex, religion,occupation, attending the skin, and V.D. outpatients Department, B.R.D. Medical College, Gorakhpurfor were taken because of the subject of this study. The bulk of patients belonged to the Eastern U.P.and adjoining areas of Bihar and Nepal. The clinical criteria for diagnosis of psoriasis were thepresence of Erythematous and papulosquamous lesions with loosely adherent silvery-white scales.The auspitz's sign was demonstrated all told the cases. The detailed clinical history and examinationwere recorded. Each patient was categorized into mild to severe psoriasis. Result: The maximumpercentage of cases was aggravated by weather (winter), 55.26%, next to that was trauma 27.19%, and least after infections 4.35%. The summer and spring seasons showed an improved effecton the condition of psoriasis. Alcohol, smoking, and mental stress found no relation with psoriasis.In most cases, where the infection was associated with the disease, it had been aggravated only inchildren, and young adults and lesions were of guttate type. Pregnancy had no effect in 25.43% ofcases, while the disease was improved in 3.50% of patients and worsen in 4.35% of cases.Conclusion: Psoriasis is positively correlated with the winter season and negatively associated withSummer and Spring.

2017 ◽  
Vol 10 (2) ◽  
pp. 70-73
Author(s):  
Mohan Mogarnad ◽  
Vandana Mohta

ABSTRACT Aim To study the clinical profile of deviated nasal septum and to assess the subjective efficacy of the surgical outcome using Likert scale. Materials and methods This study is a prospective, observational, single-center study from October 2013 to May 2015. The study was conducted in Sri Siddhartha Medical College, Tumkur, Karnataka, India. A detailed clinical history was taken and clinical examination of the patient was carried out. Sixty symptomatic patients were taken up. Patient scored their symptom-related severity using a Likert scale preoperatively. All patients underwent conventional septoplasty. Postoperatively, their symptoms were scored on 30th, 45th, and 90th day. Results Preoperative and Postoperative values were analyzed. Statistically significant improvement was observed in the entire population: Nasal obstruction (p<0.001), headache (p<0.001), nasal discharge (p<0.001), facial pain (p<0.001), and hyposmia (p<0.001). Patient satisfaction was high and they used fewer nasal medications. Conclusion After surgical correction of the septum and analysis of the subjective scale, i.e., Likert scale showed improvement in all symptoms. The principal benefits of septal surgery relate to improvement in nasal symptoms. How to cite this article Mogarnad M, Mohta V. A Study on Clinical Profile of Deviated Nasal Septum and to determine the Efficacy of the Surgery. Clin Rhinol An Int J 2017;10(2):70-73.


2021 ◽  
Vol 8 (2) ◽  
pp. 289
Author(s):  
Abid Ahmad Shairgojri ◽  
Khalid Mohiuddin ◽  
Amber Bashir ◽  
Muzafar Jan

Background: Cardiomyopathy constitutes a group of diseases that directly affect the structural or functional ability of myocardium. They are the most common form of heart diseases that are inherited in children and responsible for sudden deaths in healthy young adults. The Aim of our study was to provide a detailed description of clinical profile, epidemiology and etiology of cardiomyopathies in children.Methods: This was a hospital based prospective observational study, conducted over a period of two and half years from September 2017 to March 2020 in the Post Graduate Department of Pediatrics Government Medical College Srinagar. Study group included all patients aged between 1 month and 18 years diagnosed with cardiomyopathy. They were subjected to a detailed clinical history and physical examination. All the patients underwent echocardiography.Results: During the study period 37 patients were diagnosed with different types of cardiomyopathies. Dilated cardiomyopathy was commonest seen in 19 (51.35%), followed by hypertrophic cardiomyopathy 13 (35%) cases. Fast breathing was most common presenting complaint in dilated cardiomyopathy while most of cases with hypertrophic cardiomyopathy were asymptomatic. There was one case of distinct form of cardiomyopathy isolated left ventricular hypoplasia. Males were more involved 21 (56.76%) cases. Majority of patients 18 (48.64%) were less than one year at time of diagnosis. Parental consanguity was seen in 6 (16.22%) cases. Underlying cause was identified in 10 (27.02%) cases with myocarditis being the commonest cause.Conclusions: Pediatric cardiomyopathy represents a considerable percentage of children with cardiac disorders. Dilated cardiomyopathy is the most common type usually presented with congestive heart failure, majority of cases of hypertrophic CMP were asymptomatic. Male preponderance was seen in dilated and hypertrophic cardiomyopathy. Parental consanguinity was seen in significant number of patients. Myocarditis and inborn error of metabolism was seen in significant number of patients.


Author(s):  
Karthik Rao ◽  
Gurukanth Rao ◽  
Navin Patil ◽  
Balaji Ommurugan ◽  
N R Rao ◽  
...  

OBJECTIVE To study the incidence, age and sex distribution among adults, various modes of presentation, correlation between thrombocytopenia and bleeding manifestations and various modalities of treatment of Idiopathic Thrombocytopenic Purpura in a tertiary care hospital in India.MATERIALS AND METHODSProspective study consisting of 4o cases of ITP admitted to Kasturba Medical College Hospital, Manipal from November 2005 to March 2007. Patients above 14 years of age admitted with thrombocytopenia in this institution were screened based on detailed clinical history, physical examination and laboratory investigations.RESULTSThe maximum incidence was in the 3 rd decade of life accounting for 27.5% of the patients. Ratio of male to female was 1:1.9 with female preponderance. Females in 3 rd decade had maximum incidence while males in 4th decade have maximum incidence. Majority 12 (85.71%) of male patients and 15(57.69%) of female patients  developed purpura during the course of disease. The mean count was 17.8X109/L with range between 2.0 X109/L to 76 X109/L. Cutaneous bleeding spots were found to be assosiated with counts above 25000X109/L and hematuria with lowest counts around 4000 X109/L. 20 (50%) of the above 40 patients responded to corticposteroids alone and did not have any further relapse. Among the remaining patients 3 (7.5%) had a relapse of symptoms within next 6 months and responded to repeat prednisolone started at 1mg/kg. 2 (5%) patients were given steroids tapering dose with IV Immune globulins for initial 5 days as therapy to which they responded.CONCLUSIONIdiopathic thrombocytopenia is 1.9 times more common in females than males. Most common presentation is bleeding spots over body. Bleeding manifestations are more common with thrombocytopenia less than 30000/mm3. Corticosteroids are the mainstay in treatment. Complete remission is seen in up to 57.5% of the patients. Splenectomy is the second modality of treatment in ITP. Complete and sustained remission is seen 75% of patients.  


2021 ◽  
Vol 53 (1-2) ◽  
pp. 3-7
Author(s):  
Md Nazrul Islam ◽  
Sabikun Nahar Chowdhury ◽  
SK Moazzem Hossain ◽  
Arina Shorani Mousi

Background: Dengue is a very common seasonal public health problem causing significant mortality every year. In 2019 an outbreak occurred in Bangladesh. Few new manifestations and multi organ involvement were found. Objective: The objective of the study was to see the clinical and laboratory manifestations and outcome of dengue fever in a medical college hospital. Methods: It was an observational study in a medical college hospital in Bangladesh. Study period was one year. The patients were confirmed cases of dengue. Apart from detailed clinical history, examination of patient, relevant investigations and follow up was done until discharge. Result: Total number of cases was 98. Out of them 62 (63.2%) were male and 36 (36.73%) were female. Fever was most common (100%) manifestation and duration of fever ranged from 5 to 8 days with a mean duration of 6.3 (± 1.0) days. Among other symptoms generalized body ache was most common (63, 64.3%). Generalized weakness was present in 60 cases (61.2% cases) Bleeding manifestations was present in 41 cases; abdominal manifestations were found in 11 cases. Blood for NSI was positive in 94 (95.9%) cases; most cases (71, 72.4%) became positive between 2nd to 4th day. Ninety (91.9%) cases developed thrombocylopcnia and it started at 5th day in 45 (45.9%) cases. Blood transfusion was given in 12 (12.2%) cases & Platelet transfusion was given in 3 (3.1%) cases. Complete recovery was in 96 (98%) cases and Death occurred in 2 (2.0%) cases. Conclusion: Bleeding was a dominant presentation. Some atypical manifestations like gastro intestinal features were also observed. These findings will help physicians in early diagnosis of dengue. Bang Med J Khulna 2020: 53 : 3-7


2020 ◽  
Vol 11 (3) ◽  
pp. 3329-3337
Author(s):  
Anupam Kakade ◽  
Mangesh Padamwar ◽  
Ajonish Kamble ◽  
Yashwant Lamture ◽  
Meenakshi Yeola

One of the most common problems experienced in surgical practice, which challenges the surgeon and needs the ability to diagnose through knowing the anatomy and pathological process that can occur inside the abdomen, is a mass in the right iliac fossa. The purpose of this research was to examine clinical appearance, differential diagnosis and treatment methods for patients with the right iliac fossa.Study was carried out in the Dept. of General Surgery at Jawaharlal Nehru Medical College and Acharya Vinoba Bhave Rural Hospital, Sawangi (M), Wardha , Maharashtra , between August 2018 to December 2019. 43 patients with signs and symptoms of right iliac fossa mass were studied by taking detailed clinical history, physical examination, and were subjected to various investigations.In the present study appendicular mass constituted 60.46%, appendicular abscess 09.30% ,ileocaecal tuberculosis 06.97 % , carcinoma caecum 13.95 % , intussusseption02.32%. Patients presented with constitutional symptoms like pain , fever , vomiting , weight loss.Appendicular lump remains the most common entity in right iliac fossa mass patients. Ileocaecal tuberculosis is one of the most common differential diagnosis to be considered for pain abdomen evaluation in rural population. Conservative treatment followed by interval appendicectomy remains the main management modality in appendicular lump. The rare cause of mass in right iliac fossa as intussusception should be kept in mind.


2018 ◽  
Vol 17 (03) ◽  
pp. 111-117
Author(s):  
Pallavi Sachdeva ◽  
Sadasivan Sitaraman ◽  
Priyanka Minocha ◽  
Rohit Jain ◽  
Anita Choudhary ◽  
...  

AbstractGlobal developmental delay (GDD) is a relatively common pediatric issue. It can have plethora of causes. Early intervention in these children by finding the cause of developmental delay is often challenging but can definitely improve ultimate developmental outcome. The study was undertaken to study the clinical profile of children with GDD to assess the etiology of delay in these children. The study was performed in the Department of Pediatrics, SMS Medical College, Jaipur, from June 2014 to May 2015. One hundred sixty-eight children with GDD attending the child development clinic with age ≤ 5 years and development quotient < 70% were enrolled. After detailed clinical history and thorough examination, specific investigations were obtained. Data analysis was done to determine the underlying etiology. Out of 168 children studied, etiology was detected in 155 (92.3%). Most common etiology was perinatal insult (63.1%) followed by genetic (8.93%), postnatal (7.14%), metabolic (5.95%), mixed (2.98%), cerebral dysgenesis (2.38%), and congenital infections (1.79%). Microcephaly was present in 100 children. Most common etiology was found to be perinatal insult, which is a preventable cause to much extent. Newer and sophisticated investigations such as metabolic profile, genetic studies should be incorporated in the planned investigations to increase the diagnostic yield.


2018 ◽  
Vol 10 (2) ◽  
pp. 21-26 ◽  
Author(s):  
S Neupane ◽  
B Basnet

Background: Cutaneous adverse drug reactions (CADRs) range from minor reactions to several life threatening complications. Objectives: To study the clinical spectrum of cutaneous adverse drug reactions, determine the causative drugs responsible for the reactions and to assess the preventability.Methods: The study was carried out in the Department of Dermatology of Gandaki Medical College Teaching Hospital from June 2011 to June 2015. All the patients attending the Dermatology Outpatient Department and the patients admitted in the wards with suspected cutaneous adverse drug reactions to systemic drugs were included in the study. A detailed clinical history, including the history of drug intake was noted. Each case was assessed for its causality by using the WHO definitions. Data analysis was done using SPSS software.Results: There were 102 patients in total. The mean age of the patient was 32 ±15.7 years. Maximum patients belonged to the 21 to 30 years age group. There were 59 female patients and 43 male patients. Severe type of cutaneous adverse drug reactions was noted in 7.8% of patients. Antibiotics were responsible for most of the cutaneous adverse drug reactions. Cefixime was the most commonly incriminated drug. Exanthematous drug reaction was the most common type seen in 45%. Stevens-Johnson syndrome was the commonest type noted among the serious adverse drug reactions. Drug preventability was noted in 6% of patients.Conclusions: The commonest type of CADR noted was exanthematous type. Antibiotics were the commonest drug group involved in CADR. Six percent of CADR were preventable. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 21-26


2020 ◽  
Vol 11 (1) ◽  
pp. 16-21
Author(s):  
Md Haroon Ur Rashid ◽  
Rezaul Karim Chowdhury ◽  
Mashah Binte Amin ◽  
Md Momenuzzaman Khan

Background: COPD is a widely prevalent disease with high morbidity and mortality and is associated with various comorbidities, among which is osteoporosis. However, osteoporosis is often undiagnosed in these patients. Material and methods: This study was conducted on 40 patients with COPD and 15 healthy controls (the control group). They were selected from EMCH from Jan 2015 to Dec 2017. All participants were subjected to detailed clinical history taking, a thorough clinical examination, plain chest radiography (posteroanterior and lateral views), blood sampling for complete blood picture, erythrocyte sedimentation rate, and serum calcium and phosphates, ventilatory function tests (spirometry), and measurement of bone density using dual-energy X-ray absorptiometry (DEXA). Results: The results of this study revealed prevalence of osteoporosis was higher in the COPD group compared with the control group (P < 0.00). Prevalence of osteoporosis increased with increasing severity of COPD (P < 0.00). Conclusion: Osteopenia and osteoporosis are more prevalent in COPD patients than in healthy controls and the severity of osteoporosis increases with increasing severity of COPD. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 16-21


2020 ◽  
Vol 7 (4) ◽  
pp. 541
Author(s):  
Usham Gangaram ◽  
Giri Raju Sarikonda ◽  
Bhimasen Soren ◽  
Venkatakrishnan .

Background: Malaria is a major health problem in many parts of India and some parts of Andhra Pradesh is one of the endemic areas for malaria. The objective was to study clinical profile and outcome of malaria in both species and mixed infection.Methods: Present study was carried out on 100 patients admitted during the period of  November 2016 - October 2018 in Narayana medical college and hospital, Nellore. Malaria confirmed by Peripheral thick and thin smear or Antigen Assay underwent detailed clinical history and physical examination. This was followed by monitoring the outcome of the patients with respect to morbidity and mortality.Results: Out Of the 100 patients 58 patients were from rural background, males were predominant, most common age group was 20-30 (34%) followed by 31-40 (31%). Out of 100 patients, 54 patients were  falciparum,44 patients had vivax  and two had mixed infection. All of the patients had fever followed by chills and rigors (75%), nausea and vomiting (59%), easy fatiguability (28%), pain abdomen (17), cough (14%) in both infections, altered sensorium was seen in only falciparum (20.3%). On clinical examination,70% of the patients had pallor, splenomegaly in 46%, icterus (23%), hepatomegaly (14%) and pedal edema in12 patients were observed. All 0f the patients were treated with appropriate antimalarial drugs for appropriate duration, and all were recovered without any mortality.Conclusions:Malaria is very common disease in our country especially in South India, which is one of the endemic areas. Severe malaria usually caused by the falciparum more than vivax, early diagnosis and treatment decreases the mortality and morbidity. 


2021 ◽  
pp. 56-57
Author(s):  
T. Anandachockaling am ◽  
J. Balasubramani

Deviated nasal septum is one of the most common ENTnding . we did this study to nd out the clinical prole of deviated nasal septum Materials and methods: This study is a prospective, observational,single-center study .The study was conducted in Government sivagangai medical college hospital , sivagangai , tamil, India. A detailed clinical history was taken and clinical examination of the patient was carried out. Sixty symptomatic patients were taken up. Patient scored their symptom-related severity using a Likert scale preoperatively. All patients underwent conventional septoplasty. Postoperatively,their symptoms were scored on 30th, 45th, and 90th day. Results: Preoperative and Postoperative values were analyzed.Statistically signicant improvement was observed in the entire population: Nasal obstruction (p<0.001), headache(p<0.001), nasal discharge (p<0.001), facial pain (p<0.001),and hyposmia (p<0.001). Patient satisfaction was high and they used fewer nasal medications. Conclusion:After surgical correction of the septum and analysis of the subjective scale showed improvement in all symptoms.


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