scholarly journals Levels and health risk assessment of organochlorine pesticide residues in vegetables from Yamaltu area in Gombe, Nigeria

2021 ◽  
Vol 9 (1) ◽  
pp. 19-30
Author(s):  
Mohammad Sulaiman ◽  
Aishatu Maigari ◽  
Janefrances Ihedioha ◽  
Rasheed Lawal ◽  
Abdullahi Gimba ◽  
...  
Keyword(s):  
Health Risks ◽  
High Performance ◽  
Health Effect ◽  
Daily Intake ◽  
Hazard Index ◽  
Acceptable Daily Intake ◽  
Estimated Daily Intake ◽  
Organochlorine Pesticide Residues ◽  
The Mean ◽  
Almost All

The study determined the levels of organochlorine pesticides (OCPs) residues and assesses health risks linked with the consumption of vegetables cultivated in the Yamaltu area in Gombe, Nigeria. OCPs residues were solvent extracted and analyzed with a high performance liquid chromatography equipped with UV/VIS Detector. The mean concentrations of ten detected OCPs residues were almost all above the set limit of EU/WHOMRL. The estimated daily intake of OCPs from samples was below the acceptable daily intake, hazard index estimated were <1, indicated no probable non-carcinogenic health effect, while the carcinogenic health effect showed that children were more vulnerable for the consumption of the contaminated vegetables.

scholarly journals The occurrence of aflatoxins and human health risk estimations in randomly obtained maize from some markets in Ghana

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nii Korley Kortei ◽  
Theophilus Annan ◽  
Papa Toah Akonor ◽  
Seidu A. Richard ◽  
Helen Ama Annan ◽  
...  
Keyword(s):  
Food Safety ◽  
High Performance ◽  
Hazard Quotient ◽  
Human Health Risk ◽  
Daily Intake ◽  
Hazard Index ◽  
Estimated Daily Intake ◽  
Ecological Zones ◽  
Adverse Health ◽  
Margin Of Exposure

AbstractMaize and its products are most often prone to fungal contamination especially during cultivation and storage by toxigenic fungi. Aflatoxicosis still persist in Ghana despite the numerous education on several ways of its prevention at the farm as well as its adverse health implications which are food safety concerns. A random assessment and human risk analysis was conducted on 90 maize (72 white and 18 colored) samples from markets across all the regions of Ghana. Total aflatoxins (AFtotal) and the constitutive aflatoxins (AFB1, AFB2, AFG1, and AFG2) were analyzed by High-Performance Liquid Chromatography (HPLC). Out of a total of ninety (90) samples investigated, 72 (80%) tested positive for AFB1 and the contamination levels ranged from 0.78 ± 0.04 to 339.3 ± 8.6 µg kg−1. Similarly, AFG2 was detected in only 14 (15.5%) samples, and their values ranged between 1.09 ± 0.03 and 5.51 ± 0.26 µg kg−1 while AF total ranged between 0.78 ± 0.04 and 445.01 ± 8.9 µg kg−1 constituting approximately 72 (80%). Limits of AFB1 and total aflatoxins (AFtotal) for the Ghana Standards Authority (GSA) (5 and 10 µg kg−1) and the European Food Safety Authority (EFSA) (2 and 4 µg kg−1), were used as checks. A total of 33 (41.25%) samples were above the limits for both. Risk assessments recorded for Estimated Daily Intake (EDI), Hazard Quotient (H.Q), Hazard Index (H.I), Margin of Exposure (MOE), av. Potency, and population risks ranged 0.087–0.38 μg kg−1 bw day−1, 1.5–6.9, 0.0087–0.38, 3.64–12.09, 0–0.0396 ng Aflatoxins kg−1 bw day−1 and, 3.5 × 10–1–0.015 respectively for total aflatoxins. While ranges for aflatoxins B1 (AFB1) recorded were 0.068–0.3 μg Kg bw−1 day−1, 2.43–10.64, 0.0068–0.030, 4.73–20.51, 0–0.0396 ng Aflatoxins kg−1 bw day−1 and, 2.69 × 10–3–0.012 for Estimated Daily Intake (EDI), Hazard Quotient (H.Q), Hazard Index (H.I), Margin of Exposure (MOE), Av. potency, and population risks respectively. It was deduced that although there was some observed contamination of maize across the different ecological zones, the consumption of maize (white and colored) posed no adverse health effects on the population of Ghana since computed H.I was less than 1 (< 1).

scholarly journals The Occurrence of Aflatoxins and Human Health Risk Estimations in Randomly Obtained Maize from Some Markets in Ghana

2021 ◽  
Author(s):  
Nii Korley Kortei ◽  
Theophilus Annan ◽  
Papa Toah Akonor ◽  
Seidu Richard ◽  
Helen Annan ◽  
...  
Keyword(s):  
Food Safety ◽  
High Performance ◽  
Hazard Quotient ◽  
Human Health Risk ◽  
Daily Intake ◽  
Hazard Index ◽  
Estimated Daily Intake ◽  
Ecological Zones ◽  
Adverse Health ◽  
Margin Of Exposure

Abstract Maize and its products are most often prone to fungal contamination especially during cultivation and storage by toxigenic fungi. Aflatoxicosis still persist in Ghana despite the numerous education on several ways of its prevention at the farm as well as its adverse health implications which are food safety concerns. A random assessment and human risk analysis was conducted on 90 maize (72 white and 18 colored) samples from markets across all the regions of Ghana. Total aflatoxins (AFtotal) and the constitutive aflatoxins (AFB1, AFB2, AFG1, and AFG2) were analyzed by High-Performance Liquid Chromatography (HPLC). Out of a total of ninety (90) samples investigated, 72 (80%) tested positive for AFB1 and the contamination levels ranged from 0.78 ± 0.04–339.3 ± 8.6µg/kg. Similarly, AFG2 was detected in only 14 (15.5%) samples, and their values ranged between 1.09 ± 0.03–5.51 ± 0.26 µg/kg while AF total ranged between 0.78 ± 0.04- 445.01 ± 8.9 µg/kg constituting approximately 72 (80%). Limits of AFB1 and total aflatoxins (AFtotal) for the Ghana Standards Authority (GSA) (5 and 10 µg/kg) and the European Food Safety Authority (EFSA) (2 and 4 µg/kg), were used as checks. A total of 33 (41.25%) samples were above the limits for both. Risk assessments recorded for Estimated Daily Intake (EDI), Hazard Quotient (H.Q), Hazard Index (H.I), Margin of Exposure (MOE), av. Potency, and population risks ranged 0.087–0.38 µg/Kg.bw/day, 1.5–6.9, 0.0087-0.38, 3.64–12.09, 0-0.0396 ng Aflatoxins kg− 1bwday− 1 and, 3.5x10− 1 – 0.015 respectively for total aflatoxins. While ranges for aflatoxins B1 (AFB1) recorded were 0.068-0.3 µg/Kg.bw/day, 2.43–10.64, 0.0068-0.030, 4.73–20.51, 0-0.0396 ng Aflatoxins kg− 1bwday− 1 and, 2.69 x10− 3-0.012 for Estimated Daily Intake (EDI), Hazard Quotient (H.Q), Hazard Index (H.I), Margin of Exposure (MOE), Av. potency, and population risks respectively. It was deduced that although there was some observed contamination of maize across the different ecological zones, the consumption of maize (white and colored) posed no adverse health effects on the population of Ghana since computed H.I was less than 1 (< 1).

scholarly journals Pesticide residues in selected vegetables from Gombe markets, Gombe State, Nigeria: assessing the health impact

2021 ◽  
Vol 23 (1) ◽  
pp. 77-87
Author(s):  
A.U. Maigari ◽  
M.B. Sulaiman ◽  
M. Buhari ◽  
A.O. Abdullahi
Keyword(s):  
Health Risk ◽  
Pesticide Residues ◽  
High Performance ◽  
Health Effect ◽  
Daily Intake ◽  
Hazard Index ◽  
Health Impact ◽  
Daily Intakes ◽  
Risk Parameters ◽  
Order Four

The study determined the content of pesticide residues in vegetables (cabbage, lettuce, calyces, and tiger nut), obtained from markets in Gombe, Nigeria. Health risk parameters were also determined to evaluate the health risk associated with their consumption. A total of 72 samples (cabbage, lettuce, calyces and tiger nut) were analyzed using high performance liquid chromatography with UV/VIS Detector (HPLC-UV/VIS). A total of 18 pesticide residues were detected: nine organochlorines (OCs), five organophosphates (OPs), and  four pyrethroids (PYs). The residual contents of nine OCs ranged from 0.00 to 0.098 μg/kg and found in 61.87%, 60.99%, 63.69%, and 63.89% of cabbage, lettuce, calyces and tiger nut samples respectively, five OPs with concentrations ranging from 0.00 to 0.043 μg/kg were found in 22.69%, 21.89%, 19.49% and 22.21% of cabbage, lettuce, calyces and tiger nut samples respectively. In similar order, four PYs with concentrations that ranged from 0.00 to 0.046 μg/kg were found in 15.44%, 17.04%, 16.82% and 13.89% of the vegetables. Themean estimated daily intake of pesticides in the studied samples was lower than that of acceptable daily intakes. The hazard index obtained was less than one, indicating no probable adverse health effect on both children and adult consumers. However, monitoring and continuous stringent regulation should be imposed with regard to the usage of pesticides in vegetables, and other food stuff for public health protection. Keywords: Hazard Index, Health risk, Nut, Pesticide residues, Vegetables

scholarly journals Kandungan Logam Berat (Pb dan Hg) pada Sayuran di Desa Kopeng Kabupaten Semarang dan Analisis Risiko Kesehatan Lingkungannya

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Indira Casheila Anindityo ◽  
Nur Endah Wahyuningsih ◽  
Yusniar Hanani Darundiati
Keyword(s):  
Heavy Metal ◽  
Health Risk ◽  
Health Risks ◽  
Random Sampling ◽  
Heavy Metal Contamination ◽  
Daily Intake ◽  
Hazard Index ◽  
Lifetime Risk ◽  
Estimated Daily Intake ◽  
Running Water

Abstrak : Desa Kopeng, Kabupaten Semarang merupakan kawasan pertanian sayuran. Kegiatan pertanian seperti penggunaan pestisida dapat menyebabkan kontaminasi logam berat pada sayuran dan dapat mengganggu kesehatan yang bersifat karsinogenik pada logam berat timbal dan non-karsinogenik pada logam berat merkruri pada setiap orang yang mengkonsumsinya secara teratur. Penelitian ini bertujuan untuk mengetahui konsentrasi timbal dan merkuri pada sayuran di Desa Kopeng dan mengetahui risiko kesehatannya yang merupakan penelitian deskriptif kuantitatif dengan metode uji laboratorium menggunakan spektrometri serapan atom dan analisis risiko kesehatan lingkungan. Sampel penelitian sebanyak 15 diambil secara proporsional random sampling. Terdiri dari sayuran kubis, brokoli dan selada. Perhitungan risiko kesehatan non-karsinogenik dan karsinogenik meliputi estimated daily intake (EDI); hazard quotients (HQ) dan hazard index (HI); serta lifetime risk cancer (LCR) untuk logam berat Pb. Diperoleh rata-rata kandungan Pb pada seluruh sayuran sebesar 0,069 dan Hg <0,002 mg/kg. Hasil tersebut berada di bawah nilai ambang batas logam berat sayuran yaitu 0,5 untuk Pb dan 0,03 mg/kg untuk Hg. Perhitungan risiko kesehatan karsinogenik pada konsumsi kubis, brokoli dan selada di Desa Kopeng belum memberikan risiko kesehatan, namun pada perhitungan risiko kesehatan non-karsinogenik HI pada anak-anak sudah berisiko. Sebaiknya mengonsumsi sayuran dan buah-buahan yang beragam dan dan dicuci menggunakan air bersih dan mengalir sebelum dikonsumsi.Kata Kunci: sayuran; timbal; merkuri; risiko kesehatan; KopengAbstract: Kopeng in Distric Semarang is a vegetables agricultural area. Agricultural activities such as the use of pesticides can cause heavy metal contamination of vegetables and can cause health problems which are carcinogenic to heavy metal lead and non-carcinogenic to heavy metal mercury in everyone who consumes them regularly. This study aims to determine the concentration of lead and mercury in vegetables in Kopeng and to determine their health risks. This research is a quantitative descriptive study using laboratory test methods using atomic absorption spectrometry and environmental health risk analysis. The research sample 15 was taken by proportional random sampling. Consisting of cabbage vegetables, broccoli and lettuce. Calculations of non-carcinogenic and carcinogenic health risks include estimated daily intake (EDI); hazard quotients (HQ) and hazard index (HI); and lifetime risk cancer (LCR) for heavy metal Pb. Results an average Pb content in all vegetables of 0.069 and Hg <0.002 mg/kg. These results are below the threshold values for heavy metals in vegetables, namely 0.5 for Pb and 0.03 mg/kg for Hg. Calculation of carcinogenic health risks in the consumption of cabbage, broccoli and lettuce in Kopeng Village has not provided a health risk, but the non-carcinogenic health risk of HI in children is already at risk. We recommend that you eat a variety of vegetables and fruits and wash them using clean and running water before consumption.Keywords: vegetables; lead; mercury; health risk; Kopeng

Concentration and Risk Assessment of Potentially Toxic Elements, Lead and Cadmium, in Vegetables and Cereals Consumed in Western Iran

2019 ◽  
Vol 83 (1) ◽  
pp. 101-107 ◽  
Author(s):  
ALI HESHMATI ◽  
FERESHTEH MEHRI ◽  
JAVAD KARAMI-MOMTAZ ◽  
AMIN MOUSAVI KHANEGHAH
Keyword(s):  
European Union ◽  
Health Risks ◽  
Toxic Elements ◽  
Daily Intake ◽  
Potentially Toxic Elements ◽  
Estimated Daily Intake ◽  
The European Union ◽  
Wet Weight ◽  
Rice Samples ◽  
The Mean

ABSTRACT The concentration of cadmium (Cd) and lead (Pb) in vegetable (potatoes, onions, tomatoes, lettuce, leeks, and carrots) and cereal (wheat and rice) samples collected from Iran were investigated by a graphite furnace atomic absorption spectrophotometer. In addition, we determined the health risks due to exposure to Cd and Pb through vegetable and cereal consumption by computing the estimated daily intake, the target hazard quotient (THQ), the total THQ, and the margin of exposure. The mean concentrations of Pb in potato, onion, tomato, lettuce, leek, carrot, wheat, and rice samples were measured as 0.029 ± 0.011, 0.016 ± 0.012, 0.007 ± 0.005, 0.022 ± 0.020, 0.040 ± 0.048, 0.029 ± 0.025, 0.123 ± 0.120, and 0.097 ± 0.059 mg kg−1 wet weight, respectively, and all were below the maximum allowable concentrations set by the European Union. The mean concentrations of Cd in potatoes, onions, tomatoes, lettuce, leeks, carrots, wheat, and rice samples were measured as 0.022 ± 0.013, 0.011 ± 0.009, 0.003 ± 0.003, 0.007 ± 0.005, 0.015 ± 0.024, 0.013 ± 0.011, 0.046 ± 0.043, and 0.049 ± 0.04 mg kg−1 wet weight, respectively, and all were below the permissible levels established by the European Union. The corresponding values for the estimated daily intake of Cd were acceptable and lower than the provisional tolerable daily intake. The THQ and total THQ values of Cd through consumption of all vegetables and cereals were lower than 1. The margin of exposure values for Pb in samples were &gt;1, showing no significant human health risks for both potentially toxic elements. The findings of this study indicated there is no risk associated with exposure to Pb and Cd through the intake of selected vegetables and cereals in western Iran. HIGHLIGHTS

scholarly journals Tingkat Keamanan Konsumsi Residu Karbamat dalam Buah dan Sayur Menurut Analisis Pascakolom Kromatografi Cair Kinerja Tinggi

2013 ◽  
Vol 7 (7) ◽  
pp. 317 ◽  
Author(s):  
Bambang Wispriyono ◽  
Arry Yanuar ◽  
Laila Fitria
Keyword(s):  
High Performance ◽  
Fruits And Vegetables ◽  
Health Effect ◽  
Daily Intake ◽  
Human Consumption ◽  
Acceptable Daily Intake ◽  
Fluorescence Detector ◽  
Traditional Market ◽  
Margin Of Safety ◽  
Wet Weight

Karbamat merupakan salah satu jenis pestisida yang banyak digunakan untuk membasmi hama buah dan sayur. Untuk menentukan bahwa residu karbamat dalam sayuran masih aman dikonsumsi manusia, telah dilakukan analisis beberapa residu karbamat seperti metomil, karbaril, karbofuran, dan propoksur. Sampel-sampel tomat, apel, selada air, kubis, dan sawi hijau dikumpulkan dari tiga supermarket dan satu pasar tradisional di Depok, Jawa Barat. Analisis dilakukan serempak untuk ke empat residu karbamat menggunakan kromatografi cair kinerja tinggi denganpereaksi o-ftalaldehida dan 2-merkaptoetanol dalam reaktor pascakolom dengan detektor fluoresensi. Dari sampel-sampel buah dan sayur yang dianalisis, hanya sawi hijau asal pasar tradisional yang positif mengandung propoksur dengan kadar 1,2 mg/25 gram berat basah (0,048 mg/g berat basah). Dengan Acceptable Daily Intake(ADI) propoksur 0,005 mg/kg berat badan/hari, konsumsi sawi hijau harian seberat 20 g/hari masih cukup aman dari gangguan kesehatan akibat pajanan kronik propoksur dengan margin of safety 298,7 (> 100 sebagai batas aman).Carbamat is a group of pesticides which is commonly used to control fruits and vegetables pests. To determine that carbamat residues in fruits and vegetables are safe for human consumption, carbamate residues such as methomyl, carbaryl, carbofuran, and propoxur in vegetables and fruits have been analyzed. Samples of tomato, apple, water lettuces, cabbage, and mustard greens were collected from three supermarkets and one traditional market in Depok, West Java. The analysis was carried out simultaneously for all four carbamate residues by high performance liquid chromatography using o-phtaladehyde and 2 mercaptoethanol reagents in post-column reactor with a fluorescence detector. Of fruits and vegetable samples analyzed, only mustard greens from traditional market positively containe propoxur at 1.2 mg/ 25 gram wet weight (0,048 mg/gram wet weight). With Acceptable Daily Intake (ADI) of 0.005 mg/kg body weight/day, mustard greens consumption of 20 g/day is safe from adverse health effect from chronic exposure to propoxur with Margin of Safety of 298.7 (> 100 as safe limit).

scholarly journals Assessing the Risk of Antibiotic Residues in Milk Produced in the Republic of Armenia

2021 ◽  
pp. 199-202
Author(s):  
D.A. Pipoyan ◽  
M.R. Beglaryan ◽  
G.K. Gharibyan ◽  
A.A. Aghababyan
Keyword(s):  
Human Health ◽  
Health Risks ◽  
Daily Intake ◽  
Antibiotic Exposure ◽  
Antibiotic Residues ◽  
Acceptable Daily Intake ◽  
Estimated Daily Intake ◽  
Domestic Production ◽  
Human Health Risks ◽  
The Republic

This research sets out to assess both the antibiotic exposure via milk produced in the Republic of Armenia and the associated human health risks. As established, the milk of domestic production contains residual antibiotics (streptomycin, chloramphenicol, tetracyclines). The estimated daily intake (EDI) and the margin of exposure (MOE) for the antibiotics identified upon this research were assessed. It has been indicated that for the population of Yerevan, the daily intake of antibiotics via milk does not exceed the acceptable daily intake (ADI). Moreover, the derived MOE values point to the absence of health risks associated with shop-bought milk.

scholarly journals Biomonitoring and Subsequent Risk Assessment of Combined Exposure to Phthalates in Iranian Children and Adolescents

2018 ◽  
Vol 15 (11) ◽  
pp. 2336 ◽  
Author(s):  
Maryam Zare Jeddi ◽  
Mohamad Eshaghi Gorji ◽  
Ivonne Rietjens ◽  
Jochem Louisse ◽  
Yuri Bruinen de Bruin ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Children And Adolescents ◽  
Health Risks ◽  
Safety Concern ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Hazard Index ◽  
Internal Exposure ◽  
Combined Exposure ◽  
Iranian Children

This study aimed to estimate the exposure and related health risks of phthalates, and to assess the health risks from combined exposure to three of the phthalates sharing the same mode of action (anti-androgenicity) in children. We determined the internal exposure of 56 Iranian children and adolescents aged 6 to 18 years by analyzing seven urinary metabolites of five phthalates. The estimated daily intake values derived from the biomonitoring data ranged from 0.01 µg/kg bw/day for butyl benzyl phthalate (BBP), to 17.85 µg/kg bw/day for di(2-ethylhexyl) phthalate (DEHP). The risk assessment revealed that not only the exposure to the individual phthalates, but also the combined exposure to the three anti-androgenic phthalates (DEHP, DBP, BBP) did not raise a safety concern (hazard index values averaged 0.2). The range of maximum cumulative ratio values varied from around 1 for most individuals to around 2 in some individuals, indicating that the combined exposures were dominated by one and in some cases by two of the three anti-androgenic phthalates, especially dibutyl phthalate (DBP) and/or DEHP. Based on biomonitoring data, the overall combined exposure of Iranian children to phthalates does not raise a concern, while reduction of exposure is best focused on DEHP and DBP that showed the highest hazard quotient.

scholarly journals Levels of Metals in Soils of Ait Ammar Iron Mine, Morocco: Human Health Risks

2017 ◽  
Vol 25 (2) ◽  
pp. 127-144
Author(s):  
Mohamed Nouri ◽  
Taoufik El Rasafi ◽  
Abdelmajid Haddioui
Keyword(s):  
Human Health ◽  
Health Risks ◽  
Hazard Index ◽  
Carcinogenic Risk ◽  
Dermal Absorption ◽  
Cancer Risks ◽  
Human Health Risks ◽  
Safe Level ◽  
Iron Mine ◽  
The Mean

Abstract The concentrations of metals were determined in soil samples collected in Ait Ammar (Oued Zem, Morocco). The mean Cd, Cr, Cu, Fe, Pb and Zn contents in the mining topsoil samples were: 2.12, 135, 34.9, 214, 9.13 and 90.8 mg kg−1, respectively. Human health risks developed from metal ingestion, dermal absorption and inhalation of soils were also evaluated. For non-carcinogenic risks, united hazard index (HI) values for children surpassed the safe level (HI=1) for Cr (13.1). Values for HI in adults (1.74) also surpassed the safe level for Cr. The HI values for Pb and Cd for children were 0.69 and 0.68, respectively. Cancer risk due to Cr surpassed the tolerable range (1E-06 to1E-04) for children (1.05E-03) and for adults (1.42E-04). Cancer risks due to Pb and Cd were within acceptable ranges for both children and adults. Furthermore, oral ingestion of soil particles contributed more highly to both carcinogenic and non-carcinogenic risk from Cr than either dermal absorption or inhalation in both children and adults.

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