scholarly journals Disease as a result of violations of the symbiotic relationship between the host and the microbiota with pathogens

2021 ◽  
Vol 23 (2) ◽  
pp. 243-252
Author(s):  
Evgeny I. Tkachenko ◽  
Vladimir B. Grinevich ◽  
Irina V. Gubonina ◽  
Yuriy A. Kravchuk ◽  
Vasily Ya. Apcel ◽  
...  

Recent achievements in many sciences have led to an understanding of the need to form new ideas about the nature of human relationships with the environment and the inner world, his health, the principles of disease formation and their prevention. There has been a transition from a collection of achievements of various sciences to a holistic paradigm that unites a person as an organism and as a person, his inner and surrounding world. It became obvious that this could not be done within the framework of the previous general theories of medicine. To this end, the authors propose a new theory of medicine: "the theory of noospheric-anthropogenic harmony". From the standpoint of this theory, the mechanisms of the relationship of microbiota and pathogens with the protective and acceptive immunity of a healthy and sick person, as well as the mechanisms of microbiota regulation, are considered. The paradigm of dysbiosis as the cause of many diseases and main homeostatic mechanisms that provide symbiotic relationships of microbiota, immunity and its role in the mechanisms of natural tolerance and formation of various disease, such as, autoimmune ones and tumors, require a change in the acceptedtreatment and prevention. A new approach should be based on using a new class of drugs metabiotics, which in their term influence microbiota.

2017 ◽  
Vol 8 (1) ◽  
pp. 22-48 ◽  
Author(s):  
Iain Mackinnon

This article employs a new approach to studying internal colonialism in northern Scotland during the 18th and 19th centuries. A common approach to examining internal colonial situations within modern state territories is to compare characteristics of the internal colonial situation with attested attributes of external colonial relations. Although this article does not reject the comparative approach, it seeks to avoid criticisms that this approach can be misleading by demonstrating that promoters and managers of projects involving land use change, territorial dispossession and industrial development in the late modern Gàidhealtachd consistently conceived of their work as projects of colonization. It further argues that the new social, cultural and political structures these projects imposed on the area's indigenous population correspond to those found in other colonial situations, and that racist and racialist attitudes towards Gaels of the time are typical of those in colonial situations during the period. The article concludes that the late modern Gàidhealtachd has been a site of internal colonization where the relationship of domination between colonizer and colonized is complex, longstanding and occurring within the imperial state. In doing so it demonstrates that the history and present of the Gaels of Scotland belongs within the ambit of an emerging indigenous research paradigm.


2016 ◽  
Vol 25 (1) ◽  
pp. 99-120
Author(s):  
Saidurrahman Saidurrahman

Abstract: Knowledge of the presence (ḥuḍūrī) with mystical experience as describe above is deemed the most popular models of knowledge in Islamic philosophy at the same coloring methodology and epistemology of Islam. Through logical arguments, semantic analysis and epistemo¬logy sharp Suhrawardī considered very successfully demonstrate authenticity huduri science as a science model of non-representational. Among the classical epistemological problems that have not been resolved until now -but able to be dissected in clear and distinct- is about the relationship of subject and object of knowledge, that is the problem more acute in modern Western philosophy. What is interesting is when when to review the issues very carefully and consistently Mehdi directing and bringing the students (who interest in Islamic philosophy) into the recesses of the inner world and the dialogue with the depth of their own existence. It is undeniable that Ha'iri Mehdi Yazdi take existentialist philosophy illumination Suhrawardī and MullaṢadrā as a main reference, as he learned the lesson of Plato, Aristotle, Plotinus, Ibn Sīnā, and al-Ṭūsī, citing the idea of a number of Western philosophers were actually familiar with the science huduri that he wanted to offer. However unique, he expertly directs their ideas to the conclusion that it is inevitable for us to acknowledge the existence of non - phenomenal knowledge. Abstrak:Pengetahuan dengan kehadiran (ḥuḍūrī) dibarengai pengalaman mistik seperti yang paprkan diatas dipandang model pengetahuan yang paling populer dalam filsafat Islam sekaligus mewarnai metodologi dan epistemologi Islam. Melalui argumen-argumen logis, analisis semantik dan epistemologi yang tajam Suhrawardī dipandang sangat berhasil mendemonstrasikan keautentikan ilmu huduri sebagai sebuah model ilmu non-representasional. Diantara problem-problem klasik episte-mologis yang belum terselesaikan hingga kini—tetapi mampu dibedah secara clear dan distink—adalah tentang hubungan subjek dan objek pengetahuan, yang problemnya makin akut dalam filsafat Barat modern. Yang menarik adalah ketika ketika mengulas masalah-masalah itu Mehdi sangat cermat dan konsisten mengarahkan dan membawa para murid-muridnya (peminat filsafat Islam) memasuki relung-relung dunia batin dan berdialog dengan kedalaman eksistensi mereka sendiri. Tak dapat dipungkiri bahwa Mehdi Ha’iri Yazdi mengambil filsafat iluminasi Suhrawardī dan eksistensialis MullaṢadrā sebagai acuan utamanya, seraya memetik pelajaran dari Plato, aristoteles, Plotinus, Ibn Sīnā, dan al-Ṭūsī, mengutip gagasan sejumlah filosof Barat yang sebetulnya asing dengan ilmu ḥuḍūrī yang hendak ia tawarkan. Akan tetapi uniknya, dengan piawai ia mengarahkan gagasan-gagasan mereka kepada penarik¬an kesimpulan bahwa adalah tak terelakkan bagi kita untuk mengakui eksistensi pengetahuan non-fenomenal itu. Keywords: ilmu ḥuḍūrī, khazanah, epistemologi, cogito ergo sum, atheisme.


This chapter focuses on understanding the use of and relationship among the features of statistics cognition: literacy, reasoning, and thinking. We argue that research on statistics cognition is fragmented, which is problematic for understanding how these constructs can be unified to support education. We then review methods of quantifying cognitions, involving studies which have attempted to categorize and parse cognitive processes. This information is then used to synthesize a new approach to understanding statistics cognition, proposing a model which makes specific predictions about the relationship of these features. The model and definitions of cognitions presented in this chapter are used as a basis of discussion cognition throughout the remainder of the book.


Author(s):  
Peter Avitabile ◽  
Stephen Pennell ◽  
John White

Students generally do not understand how basic STEM (Science, Technology, Engineering and Mathematics) material fits into all of their engineering courses. Basic material is presented in introductory courses but the relationship of the material to subsequent courses is unclear to the student since the practical relevance of the material is not necessarily presented. Students generally hit the “reset button” after each course not realizing the importance of basic STEM material. The capstone experience is supposed to “tie all the pieces together” but this occurs too late in the student’s educational career. A new multisemester interwoven dynamic systems project has been initiated to better integrate the material from differential equations, mathematical methods, laboratory measurements and dynamic systems across several semesters/courses so that the students can better understand the relationship of basic STEM material to an ongoing problem. This paper highlights the overall concept to be addressed by the new approach. The description of the project and modules under development are discussed.


2011 ◽  
Vol 138-139 ◽  
pp. 1274-1279
Author(s):  
Su Zhang ◽  
Zuo Quan Zhang ◽  
Xuan Wu ◽  
Xiao Yue Li ◽  
Rong Zhu

According to the price volume relationship of the stock, with the help of the elasticity and plasticity theory in the physics, some new ideas like stock equilibrium price, share price elasticity, and share price plasticity are put forward. Then elasticity and plasticity model of the stock price are built on account of the relationship between share price and trading volume, and model parameters are tested by a kind of software calling Eviews from econometrics. In the end, we get relatively scientific result.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Jianhua Cheng ◽  
Jing Wang ◽  
Lin Zhao

The principle of the traditional attitude solution approach based on GPS (Global Position System) is to get the attitude matrix according to the relationship of coordinates. During the progress, the error of baseline position assumed in ECEF (Earth-Centered Earth-Fixed) and the error of coordinate transform between body frame and reference frame (ENU, East-North-Up) have been included in the result, and finally the precision of attitude determination is reduced. This contribution presents a new approach of attitude determination, in which the attitude angles are calculated by the double-difference carrier phase equation of GPS according to the relationship of attitude matrix and attitude angles through least-squares estimate method. The new approach predigests the procedure of attitude determination which reduces the error assumed. According to the analysis the precision of attitude determination is higher than that of traditional method. It is shown it gets a precise attitude result with the direct attitude determination method in the simulation. A novel algorithm is proposed to solve some problems. Simulation results show the effectiveness of the proposed algorithm.


2014 ◽  
Vol 12 ◽  
pp. 164-170
Author(s):  
Alžbeta Križánková

The year 1973 was a breakthrough year in the development of architecture. It triggered a crisis in society as well as the end of a period of relative prosperity and wasting of energy, which until then did not constitute a limiting factor. The crisis has forced to seek a new and more efficient architecture. The following decades were each in their own way characteristic particular in how architects approached to reduce the energy consumption of buildings and how they resolved the relationship of the building to the surrounding and the environment at all. My paper maps ecological ideas in architecture in Slovakia on the background of broader context. Initial decade was about searching and experiments. Mainly theoretical and research projects appeared. In the following period, first projects implementing ecological ides were built, e.g. experimental residential house in Holíč or solar house in Levice. Ecological aspects in architecture ascended to the real centre of interest in Slovakia from the 90s. After the change of political situation, sustainability was perceived more intense, as evidenced by a greater number of ecological houses of this period. Alternative building materials as well as the effort to reduce energy consumption were the driving force to the design of new buildings. New ideas often associated with an endeavor to define an appearance of ecological architecture are observable in many buildings, e.g. clay houses or solar collector house in Zvolen. My paper documents the development of sustainable architecture in Slovakia from the first attempts to the standardization of sustainable architecture with characteristic examples of ecologically conscious architecture of mentioned periods.


2021 ◽  
Vol 59 ◽  
pp. 37-48
Author(s):  
Nithin Varghese ◽  
Suman Sigroha

Acclaimed Kannada and English playwright, Girish Karnad’s play Broken Images focuses on human relationships and their intricacies, as well as on the relationship between languages. Outwardly, it addresses the sibling relationship and focuses on its destructive side. However, on a close reading, this monologue unfolds a series of diverse human relationships, viz., the relationship of the two sisters, Manjula and Malini; the husband-wife relationship between Manjula and Pramod; the camaraderie of Pramod and Malini; the friendship between Pramod and Lucy; and the amity between Lucy and Manjula. Besides these personal relationships, the play deals with and explores at length another important relationship, the one between two languages, one regional and one global, the legacy of the erstwhile colonizers. The relationship between Manjula and Malini acts as a metaphor for the mismatch and the hierarchy between regional language writers and Indian English writers on the Indian literary scene. This paper, therefore, examines the aforementioned human relationships in the play to reveal the motives behind the enmity and the causes which lead to sinful actions that remain invisible at all times, and in the process comments upon the relationship between different language writers, as well as what leads to the formation of existing hierarchies. First, the paper investigates the sororal bond between Manjula and Malini; second, it examines the tripartite relationships and how the third party is perceived as a rival in the relationships of Manjula-Lucy-Pramod and Manjula-Malini-Pramod; and finally, it looks at the relationship that exists between the Bhasha writers and Indian English writers, and exposes the enmity in these relationships and its various causes.


2018 ◽  
Vol 222 (1) ◽  
pp. 13-24
Author(s):  
Asst. Instructor: Ayad Enad Khalaf

This article highlights different ways of metaphorical use in language and shows its potential in attracting the readers' attention. Language as a biological being lives its own life witnessing never-ending changes: falling outs and newly built elements. We enrich our language not only by new elements but also by new styles and reusing of existing sources. One of these ways which makes language more alive and active is metaphor. Metaphor nowadays is found in all the fields of life, education, medicine, policy and everyday life. Metaphor, in fact, reflects the relationship of language to culture and the world of ideas. Language, on the one hand, is a repository of culture; the traditions, proverbs, and knowledge of our ancestors. On the other hand, language is the mirror of the world of ideas. People reflect their new ideas in using language in new ways, even such devices as paintings and riddles. Metaphor has many shapes and is found in spoken and written language, graphics, cartoon or caricature, riddles, jokes and paintings to express novel shades of meanings, e.g., metaphor in newspaper photos, magazines or even in advertisements attracts the attention of readers and are memorized for a long time. Metaphoric use is also a way of enjoying the readers. It is used for both real and logical aims such as; warnings, advises, or invitations ...etc


2020 ◽  
Vol 2020 (3) ◽  
pp. 37-50
Author(s):  
Evgeniy Butyrskiy ◽  
Vitaliy Rahuba

This article proposes a new approach to signal synthesis to ensure the stealth and safety of active location tools, which improves the efficiency of lighting. The work has been classified complex broadband signals, considered the class of polyharmonic and band signals, their pros and cons, the prospects of application in the systems of location, shows the relationship of their signals with hyperbolic function and generalized range Fibonacci.


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