scholarly journals Pathogenesis of perinatal pathology in newborns developing under conditions of chronic hypoxia with placental insufficiency

2004 ◽  
Vol 53 (2) ◽  
pp. 26-29
Author(s):  
I. I. Evsyukova

The study of the pathogenetic aspects of disorders in the formation of the functions of the central nervous system and other vital functional systems of the child's body under unfavorable conditions of its intrauterine development has always been a priority direction of scientific research by the employees of the Department of Physiology and Pathology of Newborns of the N.I. BEFORE. Otta RAMS.

2021 ◽  
Vol 20 (4) ◽  
pp. 57-64
Author(s):  
Maya A. Khan ◽  
Maria S. Petrova ◽  
Maria G. Degtyareva ◽  
Natalya A. Mikitchenko ◽  
Olga U. Smotrina ◽  
...  

The subject of this publication is the medical rehabilitation of children with perinatal lesions of the central nervous system. Currently, the main methodological principles of stage-by-stage medical rehabilitation of newborns, mainly children with the consequencesof perinatal damage to the nervous system, have been determined. Special attention should be paid to the issue of minimal use of medicines in children with perinatal pathology, in this regard, an importanttask is the development and scientific justification of new non-drug technologies of medical rehabilitation, especially in childrenunder 1 year. Medical rehabilitation sets itself the following tasks: stimulation of blood circulation in the brain tissues, improvement of muscle toneby affecting the central nervous system and the peripheral nervous system, activation of neuromuscular transmission processes andimprovement of psychomotor development of a child with perinatal pathology of the central nervous system. Medical rehabilitationof children with perinatal lesions of the central nervous system begins at the earliest possible time and is carried out by specialists ofa multidisciplinary rehabilitation team based on an individual medical rehabilitation program. Aim. To study the results of research conducted by Russian and foreign authors on the issues of physical rehabilitation of children withperinatal damage to the central nervous system and to conduct an analysis of the effectiveness of the proposed technologies. Material and methods. The literature review for this article was conducted from the elibrary, PubMed, Cochrane Library databaseswith a search depth of 10 years. The selection of publications was carried out using keywords: non-drug technologies, perinatal damageto the central nervous system; perinatal hypoxic-ischemic encephalopathy, kinesotherapy, neurodevelopmental therapy, massage,thin finger training method, dry immersion, fitball gymnastics, V. Voit therapy; Bobat therapy. Conclusion. Currently, a wide range of non-drug technologies of medical rehabilitation of children with the consequences of perinataldamage to the central nervous system is used such as therapeutic gymnastics, massage, kinesiotherapy with a neuroreflex locomotionaccording to Vojta’s method, Bobath-therapy, massage, etc. The analysis of publications has shown that kinesotherapy and massagein in the complex of rehabilitation measures for children with perinatal lesions allows to increase the effectiveness of rehabilitationmeasures, reduce the severity of motor disorders, and can help reduce the frequency of formation of cerebral palsy.


2019 ◽  
pp. 42-46
Author(s):  
Yu. L. Mizernitskiy ◽  
I. M. Melnikova ◽  
V. A. Pavlenko ◽  
V. N. Volovenko ◽  
N. M. Kondrashova

Objective: The objective is to assess the clinical efficacy of the inclusion of release-active medication of affinity purified antibodies to protein S100 in complex rehabilitation of infants with old acute obstructive bronchitis affected by perinatal pathology of central nervous system of hypoxic genesis.Methods: 210 infants aged from 2–36 months, who suffered events of acute obstructive bronchitis, were examined. Along with clinical methods of examination, a computer bronchophonography and assessment of heart rate variability were performed.Results: Additional inclusion of release-active medication ‘Tenoten for children’ in the complex of rehabilitation of these patients had a positive effect on autonomic balance and autonomic component of bronchial obstruction. At the same time, the short course of Tenoten (1 month) did not prevent recurrent events of bronchial obstruction.Conclusions: Probably, patients with recurrent events of acute bronchial obstruction in combination with pronounced functional disorders of vegetative state require longer courses of release-active medication which normalized the activity of the central nervous system.


2021 ◽  
pp. 29-39
Author(s):  
M.A. Khan ◽  
Prikuls V.F. Prikuls V.F. ◽  
N.A. Mikitchenko ◽  
O.Yu. Smotrina ◽  
Filatova E.V. Filatova E.V.

The article is dedicated to non-pharmacological rehabilitation of children with perinatal lesions of the central nervous system. Currently, the main methodological principles of the staged medical rehabilitation of newborns, mainly children with consequences of perinatal damage to the nervous system, have been determined. Special attention should be paid to the issue of the minimum use of drugs in children with perinatal pathology. In this regard, an important task is to develop and scientifically substantiate new non-drug technologies for medical rehabilitation, especially in children under 1 year of age. Medical rehabilitation has the following aims: stimulation of blood circulation in the tissues of the brain, improvement of muscle tone by acting on the central nervous system and the peripheral nervous system, activation of the processes of neuromuscular transmission and improvement of the psychomotor development of a child with perinatal pathology of the central nervous system. Medical rehabilitation of children with perinatal lesions of the central nervous system begins at the earliest possible date and is carried out by specialists of a multidisciplinary rehabilitation team based on an individual medical rehabilitation program. At present, a wide range of non-drug technologies for medical rehabilitation of children with the consequences of perinatal damage to the central nervous system is used: therapeutic gymnastics, massage, kinesitherapy with a neuroreflex component according to the V. Vojta’s method, Bobath therapy. The analysis of publications presented in the review has shown that the inclusion of modern technologies of kinesitherapy and massage in the complex of rehabilitation measures in children with perinatal lesions can increase the effectiveness of rehabilitation measures, reduce the severity of movement disorders, and decrease the incidence of cerebral palsy.


Author(s):  
Antonella Mandas

The physiology and the pathology of the Central Nervous System (CNS) is very complex, and only by understanding it the scientific research might develop effective treatments. Neurocognitive Disorders, extremely diffused diseases, have a multifactorial aetiology, in which lipid homeostasis plays an important role, as known. The aim of this mini-review is focus on interesting recently published researches on the topic, in order to put together some pieces of the puzzle of such an enormous physiopathology chapter. After a brief introduction, we will describe important aspects of CNS lipid metabolism, then we will examine the conclusions of recent articles relating to lipid role in neurodegeneration. The recent scientific literature has strengthened the position of some well-known “biological agents” – i.e. lipid peroxidation and apolipoprotein E4 allele –but also detailed the importance of new promising diagnostic and therapeutic targets.


Author(s):  
L. . Vygovskaya ◽  
A. . Samigullina ◽  
Y. . Efendiev

The study showed how the severe health condition at birth has influence on manifestation rate of the peripheral and central hearing disorders in patients with perinatal pathology of the central nervous system. The algorithm for correcting somatic dysfunctions reduces frequency and degree of neurosensory hearing disorders at the earliest child development stage, thereby promoting the integration of these patients into society.


1993 ◽  
Vol 7 (5) ◽  
pp. 508
Author(s):  
A.M. Litvinova ◽  
S.G. Baltuk ◽  
N.V. Bashmakova ◽  
V.A. Babayeva ◽  
L.I. Voronina ◽  
...  

1894 ◽  
Vol 40 (171) ◽  
pp. 673-684
Author(s):  
W. Lloyd Andriezen

After noting the importance not merely of the study of the origin, evolution, and structure of the central nervous system, but the importance of the attempt to correlate these with the actual life-activities of the organism in both health and disease, Dr. Andriezen showed how the neglect of alienists to follow and work up these investigations entailed their falling back and separation from the advancing army of neurological workers. He hoped that, with the awakening of the spirit of inquiry and scientific research in our asylums, that reproach might be wiped away, and that an attempt would be made to study and localize the lesions in the insanities, making use of all the methods available—neurological, psychological, pathological, sociological, and experimental.


Author(s):  
A. . Samigullina ◽  
L. . Vygovskaya ◽  
Y. . Efendiev

Chronic placental insufficiency and birth injuries are the main factors in the development of neurosensory disorders and somatic dysfunctions in patients with perinatal pathology of the central nervous system. Each category of patients born in the adverse conditions of the perinatal period has a certain set of somatic dysfunctions due to the influence of the pathogenetic mechanisms on the relevant anatomical landmarks


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