Genetic factors of predilection for habitual noncarrying of pregnancy at early stages

2021 ◽  
Vol 50 (2) ◽  
pp. 8-13
Author(s):  
O. N. Bespalova ◽  
O. N. Arzhanova ◽  
T. E. Ivaschenko ◽  
M. V. Aseev ◽  
E. K. Ailamazyan ◽  
...  

By means of the method of polimerase chain reaction the frequency of blank allele of genes GSTP1, GSTM1, and the frequency of polymorphous alleles of gene GSTP1 in 40 pairs with habitual noncarrying of pregnancy at early stages were studied. The results of the investigation testify to the high rate of gomozygotes GSTT1 0/0 in pairs with habitual noncarrying of pregnancy in comparison with indices in general population of North-West region of Russia (37,7% and 23,3% correspondingly). The genes GSTM1, GSTT1, GSTP1 code enzymes, which take part in the second phase of xenobiotic detoxication system. Taking into consideration that protein products of these genes to significant extent determine the effectiveness of 2nd phase of detoxication (neutralization of xenobiotics by glutathione binding), we are to suppose that unfavorable environmental factorsplay the important role in etiology and genesis of habitual noncarrying of pregnancy at early stages.

2019 ◽  
Vol 11 (2) ◽  
pp. 67-74 ◽  
Author(s):  
Z. M. Zagdyn

The penitentiary system is one of the leading factors in preservation and the spread of HIV infection and tuberculosis epidemics among the general population. The aim of the analytical review is to assess the trends of the HIV and tuberculosis epidemics, as monoinfections in prisons, and to evaluate their influence on the general situation in the North-West Region. In the study were used data from the Rosstat and the Ministry of Justice annual reporting forms during 2007–2017. Results. Tuberculosis incidence, prevalence and mortality in the North-West Region penitentiary system for the review period have significantly reduced, the HIV incidence and mortality rates also tend to go down, nevertheless the HIV prevalence is continuing to go up. At the same time, in either case, there is a significant excess of indicators in correctional system over similar data among the general population. Conclusion. In the North-West Region the tuberculosis situation in the penitentiary facilities is improving, the HIV situation is remaining problematic. The correctional system of the Arkhangelsk oblast, the Republics of Karelia and Komi and the Novgorod oblast have a greatest impact on the tuberculosis and HIV epidemic situation among the general population, the least influence is in the Kaliningrad oblast.


2017 ◽  
Vol 25 (3) ◽  
pp. 430-441
Author(s):  
Monique Aziza

This article argues that the number of unprosecuted human traffickers is growing in Cameroon. This article aims to examine Cameroonian government officials, prosecutors and judiciary attitudes to human trafficking laws, which endanger Cameroonians. This article is an empirical study of victims of human trafficking. It takes an objective look at Cameroon's anti-trafficking law that criminalises the trafficking of adults and children. It is evident that societal discrimination towards the North West region, lack of opportunities for free education or to a trade post-primary school and the lack of enforcement of the anti-trafficking law are making combating human trafficking an arduous task.


2018 ◽  
Vol 8 (2) ◽  
pp. 51-74
Author(s):  
Fonteh Athanasius Amungwa

This paper examines the impact of community education and challenges facing Centres for Education and Community Action as a rural development strategy in Cameroon. The study was conducted in the North-West Region of Cameroon, employing field observations, semi-structured interviews with key informants using a convenient sampling technique and through elaborate review of documents. These research instruments were blended into what is termed triangulation and the data collected was analysed descriptively. The main focus of qualitative analysis is to understand the ways in which people act and the accounts that people give for their actions. This paper posits that extreme dependence on the provision of Western formal education cannot solve the problems of a rapidly changing society like Cameroon, which is facing a long-term economic crisis and persistent unemployment issues of graduates. Consequently, education should be redefined in the context of the prevailing economic crisis to make it responsive to the aspirations of rural communities. Findings showed that community education had contributed towards rural development immensely but has suffered many challenges due to neglect of the field in the policy agenda. This paper recommends the integration of community education with formal education to facilitate group and community betterment in particular and rural transformation in general.


2021 ◽  
Vol 13 (11) ◽  
pp. 5964
Author(s):  
Louis Atamja ◽  
Sungjoon Yoo

The purpose of this study is to examine the effect of the rural household’s head and household characteristics on credit accessibility. This study also seeks to investigate how credit constraint affects rural household welfare in the Mezam division of the North-West region of Cameroon. Using data from a household survey questionnaire, we found that 36.88% of the households were credit-constrained, while 63.13% were unconstrained. A probit regression model was used to examine the determinants of households’ credit access, while an endogenous switching regression model was used to analyze the impact of credit constraint on household welfare. The results from the probit regression model indicate the importance of the farmer’s or trader’s organization membership, occupation, and savings to the household’s likelihood of being credit-constrained. On the other hand, a prediction from the endogenous switching regression model confirms that households with access to credit have a better standard of welfare than a constrained household. From the results, it is necessary for the government to subsidize microfinance institutions, so that they can take on the risk of offering credit to rural households.


2021 ◽  
pp. 1-13
Author(s):  
Fernando Rebollar ◽  
Rocío Aldeco-Perez ◽  
Marco A. Ramos

The general population increasingly uses digital services, meaning services which are delivered over the internet or an electronic network, and events such as pandemics have accelerated the need of using new digital services. Governments have also increased their number of digital services, however, these digital services still lack of sufficient information security, particularly integrity. Blockchain uses cryptographic techniques that allow decentralization and increase the integrity of the information it handles, but it still has disadvantages in terms of efficiency, making it incapable of implementing some digital services where a high rate of transactions are required. In order to increase its efficient, a multi-layer proposal based on blockchain is presented. It has four layers, where each layer specializes in a different type of information and uses properties of public blockchain and private blockchain. An statistical analysis is performed and the proposal is modeled showing that it maintains and even increases the integrity of the information while preserving the efficiency of transactions. Besides, the proposal can be flexible and adapt to different types of digital services. It also considers that voluntary nodes participate in the decentralization of information making it more secure, verifiable, transparent and reliable.


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