scholarly journals Clinical and immunohistochemical assessment of proliferative activity in uterine myoma

2021 ◽  
Vol 82 (1) ◽  
pp. 38-40
Author(s):  
Yu. I. Borodin ◽  
A. P. Kiyasov ◽  
I. V. Klyucharov

A tumor of the uterus, consisting of smooth muscles, is called myoma and fibroids, and in practice, the terms are used synonymously. Myoma of the uterus is a common disease in women of childbearing age. The frequency of its detection without regard to age is 2.45%. With age, its prevalence increases and reaches 8.31% by the age of 50. The estimate of the final probability of contracting uterine fibroids in the population throughout life is 9.7%. According to sectional data, uterine fibroids, including small nodes, occur in 20% of women. In 50% of cases, these tumors are manifested by clinically pronounced disorders that lead a woman to a doctor.

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 717
Author(s):  
Katarzyna Kwas ◽  
Aleksandra Nowakowska ◽  
Angelika Fornalczyk ◽  
Magda Krzycka ◽  
Anna Nowak ◽  
...  

Background and Objectives: Uterine fibroids develop in 25–40% of women of childbearing age; however, there are discrepancies resulting from population and socioeconomic differences. The pathogenesis of fibroids is not clear. The aim of the study was to assess the potential connection between the use of oral contraceptives and the occurrence of uterine fibroids in women of childbearing age. Materials and Methods: In this prospective, survey, case–control study, data were collected from Caucasian female patients (mean age = 30) using a questionnaire concerning the onset, duration and form of hormonal contraception, and medical and obstetrical history. The questionnaires were handed personally to hospitalized patients as well as distributed through Google forms on social media. Results: In a study group (n = 140) of patients using hormonal contraception, 37.8% of them were diagnosed with uterine fibroids, whereas among the patients not using hormonal contraception (n = 206), uterine fibroids were diagnosed in 59.6% of the patients. The most common hormonal contraception was two-component hormonal tablets used by 93.3% of the patients. Taking contraceptives was a uterine fibroids protective factor (OR = 0.4, p = 0.007). In the study group, 5.5% of the patients were pregnant and 60.42% were diagnosed with uterine fibroids (OR = 4.4, p < 0.000001). Conclusion: Contraception was found to be a protective factor for uterine fibroids among the women surveyed. The presented data confirm the theory about the hormonal dependence of uterine fibroids.


2021 ◽  
Vol 3 (1) ◽  
pp. 27-37
Author(s):  
Fatwa Imelda ◽  
Mula Tarigan ◽  
Lidya Eryunika

Cervical cancer is the most common disease affecting women around the world. Early detection of cervical cancer is needed by using Visual Inspection with Acetic Acid (VIA). This method is relatively easy to do, and the examination costs are also quite affordable, making it more beneficial for women. This study was to determine the determinants of the VIA Test results. It is quantitative research with a descriptive approach presented in the form of a frequency distribution table. There are 100 samples of women of childbearing age acquired by purposive sampling at Patumbak District, Deli Serdang. From the samples, some respondents receive positive IVA test result as follows: 14% aged 36-35 years old, 14% Protestant, 19% married, 9% high school graduates, 10% housewife, 15% with minimum monthly income, 12% with 3-5 children, 17% has multigravida parity, 14% married at the age of 17-25 years old, 12% first-time mother at the age of 17-25 years old, and 14% with 5+ years using IUD contraception. The study was based on the negative VIA test result but with detected pre-cancerous lesions. Further research with different variables is necessary to acquire more information regarding cervicitis incidence causes, thus, reducing cervical cancer numbers.


2016 ◽  
pp. 36-41
Author(s):  
N. V. Dubrovina ◽  
V. L. Tyutyunnik ◽  
N. E. Kan ◽  
R. S. Dokuyeva

Iron deficiency anemia is a common disease. According to various reports, it is found in the majority of women of childbearing age, pregnant and postpartum women. This is due to the high requirement of iron during gestation and increased consumption in the postpartum period. Choosing the most effective iron replacement drug the effect of which is realized within the minimum period of time could be the best solution of the problem and contribute to favorable outcomes.


Author(s):  
Hossin Ansariniya ◽  
Abolfazl Yavari ◽  
Fateme Zare ◽  
Atiyeh Javaheri

Endometriosis is a chronic and relatively common disease in women of childbearing age. Complications of this disease include a wide range of disorders. The cause of this disease is not known for sure, but several hypotheses have been proposed for it. In this disease, the entry of endometrial tissues into the peritoneal cavity causes oxidative stress through the Fenton reaction and inflammation in this site. Oxidative stress can be associated with many complications of endometriosis. In this review, an attempt has been made to discuss the effects of oxidative stress on various complications of this disease.


2020 ◽  
Vol 27 (04) ◽  
pp. 711-716
Author(s):  
Sana Amjad ◽  
Hania Iqbal ◽  
Raham Bacha ◽  
Syed Amir Gilani ◽  
Muhammad Uzair ◽  
...  

Objectives: To determine sonographic association of uterine fibroids with infertility among women of childbearing age. Study Design: Cross-sectional study. Setting: Gilani Ultrasound Clinic opposite Lahore General Hospital, University of Lahore. Ahsan Diagnostic Centre, Sialkot. Period: From 10th July to 10th October 2018. Materials & Methods: The study was started after the approval of ethical committee of the University of Lahore. All the patients were enrolled in this study after signing the informed consent form. Toshiba Xario and Medison Accuvix V20 with convex transducer frequency ranging from 2 to 6 MHz were used. Fibroids were evaluated through trans-abdominal scan and sonographic data was stored in the ultrasound machine. A convenient sampling technique was used and data was further analyzed with the help of Statistical Package for the Social Sciences version 24 (SPSS 24, IBM, Armonk, NY, United States of America). Results: Among 113 subjects, the incidence of uterine fibroid was 32.7%. A significant association (p-value=0.010) was seen between existence of fibroid and the type of Infertility. The mean size of the fibroids was found to be 32.3568mm, 26(23.0%) of participants had single while 11(9.7%) of them had multiple fibroids. The location was most commonly seen in anterior and posterior wall, whereas the most common type was found to Sub-Mucosal and Sub-Serosal. Conclusion: Uterine Fibroids were commonly associated with Secondary infertility as compared to primary infertility.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 48-52
Author(s):  
E N Kravchenko ◽  
R A Morgunov

The aim of the study. Assess the importance of pregravid preparation and outcomes of pregnancy and childbirth, depending on the reproductive attitudes of women in the city of Omsk. Materials and methods. The study included 92 women who were divided into groups: group A (n=43) - women whose pregnancy was planned; group B (n=49) - women whose pregnancy occurred accidentally. Each group was divided into subgroups depending on age: from 18 to 30 and from 31 to 49 years. For each patient included in the study, a specially designed map was filled out. These patients were interviewed at the City Clinical Perinatal Center. Results. Comparative analysis revealed the relationship between the reproductive settings of women of childbearing age and the peculiarity of the course of pregnancy and childbirth in these patients. Summary. The majority of women of fertile age are married: in subgroup AA - 25 (96.2%), AB - 13 (76.5%), BA - 25 (92.6%), BB - 20 (91.0%). The predominant number of women of fertile age have one or more abortions: in subgroup AA - 12 (46.2%), AB - 6 (35.3%), in subgroups of comparison BA - 8 (29.6%), BB - 6 (27.3%). More than half of the women of fertile age surveyed have a history of untreated cervical pathology (from 40.8% to 64.7%). The course of pregnancy in women planning pregnancy in most cases proceeded without complications: in subgroup AA - 13 (50.0%), AB - 11 (64.7%). The most common cause of complicated pregnancy in women whose pregnancy occurred accidentally is the threat of spontaneous miscarriage: in subgroup BA - 15 (55.6%), BB - 16 (72.7%). The uncomplicated course of labor more often [subgroup AA - 19 (73.0%), AB - 12 (70.6%)] was observed in women whose pregnancy was planned and they were motivated to give birth to a healthy child.


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