scholarly journals Stages of the objective assessment system development for the activities of the oncological service in Russia and the Northwestern Federal District of the Russian Federation (morbidity, mortality, index accuracy, annual mortality, median survival, observed and relative survival of patients with malignant tumors). Part II

2021 ◽  
Author(s):  
Vakhtang Merabishvili ◽  
Alexey M. Belyaev
Keyword(s):  
Russian Federation ◽  
Malignant Tumors ◽  
Objective Assessment ◽  
Relative Survival ◽  
Federal District ◽  
Assessment System ◽  
Annual Reports ◽  
Positive Trend ◽  
Oncology Research ◽  
The Russian Federation

To plan anti-cancer measures and to correctly manage its condition, it is necessary to use only reliable sources of its formation. For this purpose, a system of Population-based or territorial Cancer Registries (PCR) has been created in Russia. The first Registry was the St. Petersburg PCR, created by us in 1993, which became the school of methodological preparation of the system in the administrative territories of Russia. The corresponding Order No. 420 of April, 19, 1996 issued by the Ministry of Public Health of the Russian Federation has legitimized a new organizational structure and entrusted it with the supervision of the P. Hertsen Moscow Oncology Research Institute. Unfortunately, to date, the PCR databases are not used, when creating state reports, analytical developments on the PCR database are either not conducted, or are used extremely rarely. The only exception was the St. Petersburg PCR, and now the entire Northwestern Federal District of the Russian Federation (NWFD RF) and 6 more administrative territories operating under our programs. The materials of the real state of the oncological service, prepared on the basis of the St. Petersburg PCR database, have been published by us in more than 20 monographs in St. Petersburg and the Northwestern Federal District of Russia. In this paper, we present the dynamics of analytical indicators calculated according to the PCR database, which sharply differ from the data of the Form No. 7 Annual Reports. The calculated indicators are close to the European average and have a positive trend.

scholarly journals Stages of development of the system of objective assessment of the cancer service of Russia, the northwestern Federal district of the Russian Federation (morbidity, mortality, reliability of accounting, primary mortality, median survival, observed and relative survival of patients with malignant neoplasms). Part I.

2021 ◽  
Author(s):  
Vakhtang M. Merabishvili ◽  
Alexey M. Belyaev
Keyword(s):  
Russian Federation ◽  
Malignant Tumors ◽  
Objective Assessment ◽  
Relative Survival ◽  
Federal District ◽  
Cancer Registries ◽  
Malignant Neoplasms ◽  
Historical Outline ◽  
The Russian Federation

The first part of the study includes a brief historical outline on the creation of an objective system for assessing the activities of the oncological service in Russia and the Northwestern Federal District of the Russian Federation.Dynamic series of all types of indicators of the populations morbidity and mortality have been presented, an increasing process of reliability and improvement of the quality of registration of primary patients with malignant tumors has been shown.In Russia, aswell as in the Northwestern Federal District of the Russian Federation, standardized indicators of the malignant tumorsincidence remain at a relatively low level. In the world ranking of Cancer Registries, the Russian Federation is on 300th place among 450 others.The mortality rate of the population in most localizations isrecorded above the average European indicators.

scholarly journals Epidemiology, index of accuracy, histological structure, year-by-year lethality and survival of patients with malignant melanoma. Population study – part II

2020 ◽  
Vol 66 (6) ◽  
pp. 638-644
Author(s):  
Vakhtang Merabishvili ◽  
Elvira Merabishvili
Keyword(s):  
Malignant Melanoma ◽  
Russian Federation ◽  
Malignant Tumors ◽  
Survival Rates ◽  
Relative Survival ◽  
Federal District ◽  
Histological Structure ◽  
Skin Melanoma ◽  
Cancer Services ◽  
The Russian Federation

For any research development, we must first make sure that the material selected for research is reliable. Among the six main most reliable criteria for evaluating the performance of cancer services, such as morbidity, mortality, and the level of morphological verification of tumors – the most important indicators are the index of accuracy, primary mortality and survival of patients with malignant tumors. Purpose. To determine the level of index of accuracy for patients with skin melanoma (C43) and its dynamics from 1995 to 2018 in Russia as a whole and in a number of administrative territories. Calculate the 5-year observed and relative survival and typical mortality in the northwestern Federal district of the Russian Federation. Materials and methods of research. The material for the study is statistical collections, including author's ones, and the database of the cancer register of the northwestern Federal district of the Russian Federation. Standard methods of statistical analysis were used. Obtained result. It is important to note that for all administrative territories, whose PCR database were involved in calculating the 5-year observed and relative survival rates, the level of survival rates of patients with melanoma of the skin is significantly lower than the average European (Eurocare–4). Conclusions. Thus, the study revealed a significant improvement in the treatment of patients with malignant melanoma of the skin. At the same time, the estimated 5-year observed and relative survival rates of patients with malignant melanoma of the skin remain relatively low.

MORBIDITY, MORTALITY AND RELIABILITY OF ACCOUNTING OF PATIENTS OF DIFFERENT AGE GROUPS WITH LIVER CANCER IN RUSSIA

2020 ◽  
pp. 240-245
Author(s):  
В. М. Мерабишвили ◽  
В. К. Гуркало ◽  
Э. Н. Мерабишвили
Keyword(s):  
Liver Cancer ◽  
Russian Federation ◽  
Malignant Tumors ◽  
Primary Liver Cancer ◽  
Age Groups ◽  
Federal District ◽  
Cancer Register ◽  
The North ◽  
The Russian Federation ◽  
North Western

Рак печени (РП) - тяжелейшая онкопатология. В России смертность превышает число первично-учтенных больных в среднем. Ежегодно в России регистрируют более 8 тыс. (8 810 - в 2018 г.) случаев рака печени и более 10 тыс. (10 018 - в 2018 г.) случаев смерти от этой причины. Использованы стандартные методы медицинской статистики, все зарегистрированные первичные случаи РП в России. Углубленная разработка материала проведена на основе базы данных Популяционного ракового регистра Северо-Западного Федерального округа РФ. Проанализированы данные всего комплекса доступной информации в целом по России. Установлен прирост заболеваемости РП населения России за 18 лет в «грубых» показателях и абсолютных числах на 20% и в стандартизованных - на 1,22%. У женщин отмечено снижение учтенных случаев РП на 4,55%. Смертность населения России в стандартизованных показателях снизилась за 18 лет практически на 3%. Превышение числа умерших над заболевшими от РП существенно возрастает в старших возрастных группах. Индекс достоверности учета (ИДУ) - это отношение абсолютных чисел или «грубых» показателей смертности населения к заболеваемости. Для всех злокачественных новообразований (ЗНО) величина в среднем по России составила 0,47, практически совпадающая со среднеевропейской. ИДУ у мужчин - 0,55, выше расчетных показателей для женщин - 0,40, что в первую очередь связано с более благоприятной структурой заболеваемости женщин ЗНО. Медиана выживаемости первичных больных РП составляет немногим более 3 мес. Пятилетняя выживаемость больных РП даже на ранних стадиях составляет у лиц моложе 60 лет с I стадией - 25,3%, старше 60 лет - только 17,2%, со II стадией - 17,9 и 11% соответственно. Liver cancer is a severe oncopathology. Mortality exceeds the number of primary-accounted patients in Russia on average. Every year in Russia more than eight thousand (8 810 in 2018) cases of liver cancer and more than 10 000 (10 018 in 2018) deaths from this cause are registered. Used Standard methods of medical statistics, all registered primary cases of liver cancer in Russia. In-depth development of the material was carried out on the basis of the database of the Population cancer register of the North-Western Federal district of the Russian Federation. The analysis of the data of the whole complex of available information in Russia as a whole is carried out. In-depth data development was carried out on the basis of the database of the Population cancer register of the North-Western Federal district of the Russian Federation. The increase in the incidence of liver cancer in Russia over 18 years in «rough» indicators and absolute numbers by 20 % and in standardized by 1,22 % was established. In women, there was a decrease in reported cases of liver cancer by 4,55 %. The mortality rate of the Russian population in standardized indicators has decreased by almost 3 % over 18 years. The excess of the number of deaths over those from liver cancer increases significantly in older age groups. The index of reliability of accounting is the ratio of absolute numbers or «rough» indicators of mortality to morbidity. For all malignant tumors, its value on average in Russia was 0,47, almost coinciding with the average European. The index of reliability of accounting for men is 0,55, higher than the calculated indicators for women - 0,40, which is primarily due to a more favorable structure of the incidence of malignant tumors in women. The median survival of primary liver cancer patients is a little more than three months. The fi ve-year survival rate of patients with liver cancer even in the early stages is in the first among persons younger than 60 years - 25,3 %, over 60 years - only 17,2 %, in the second, respectively, 17,9 and 11%.

METHODICAL APPROACHES TO THE ANALYSIS OF THE ACTIVITIES OF THE CANCER SERVICE ON THE BASIS OF THE FORMS OF STATE REPORTING AND THE DATABASE OF THE POPULATION CANCER REGISTER OF THE NORTHWESTERN FEDERAL DISTRICT. PART II

2019 ◽  
Vol 65 (6) ◽  
pp. 807-815
Author(s):  
Vakhtang Merabishvili ◽  
Aleksey Belyaev
Keyword(s):  
Malignant Tumors ◽  
Objective Assessment ◽  
Survival Rates ◽  
Federal District ◽  
International Standards ◽  
First Year ◽  
Female Population ◽  
Cancer Register ◽  
The Russian Federation ◽  
Dynamic Series

On the second part of the article the main attention is paid to the analysis of survival of patients with malignant tumors calculated on the base of the database of the population cancer register of the northwestern Federal district. The main criterion for assessing the state of oncological service is 1 and 5-years observed and relative survivals of patients with malignant tumors. Unfortunately, the number of cancer registers calculating survival rates of patients with malignant tumors according to international standards is limited in Russia. We present calculations of the dynamic series of the survival median. Defects of its objective assessment are revealed. Positive dynamics of 5-year observed survival of patients with malignant tumors in the Russian Federation is shown. Dynamics of 1 and 5 year survival of cancer patients is considered in pairs taking into account sex, age and stage of disease. There has been some improvement, especially among the female population. As can be seen from the data presented at the first year of observation, about 35 percent of patients die in the region, as in the most European countries.

THE FIRST RESULTS OF THE ANALYSIS OF THE ACTIVITY OF THE CANCER SERVICE OF THE NORTH-WESTERN FEDERAL DISTRICT OF THE RUSSIAN FEDERATION, CONDUCTED ON THE BASIS OF THE CREATED POPULATION CANCER REGISTER OF THE FEDERAL DISTRICT

2020 ◽  
pp. 228-239
Author(s):  
В. М. Мерабишвили ◽  
А. М. Беляев
Keyword(s):  
Russian Federation ◽  
Cancer Incidence ◽  
Malignant Tumors ◽  
Survival Rates ◽  
Age Groups ◽  
Federal District ◽  
Cancer Service ◽  
The North ◽  
The Russian Federation ◽  
North Western

Полностью сформированная база данных Популяционного ракового регистра (БД ПРР) Северо-Западного Федерального округа Российской Федерации (СЗФО РФ) в феврале 2019 г. позволила существенно расширить возможности объективной оценки деятельности онкологической службы на более надежной основе аналитических материалов. В России впервые появилась возможность проводить эпидемиологические исследования злокачественных новообразований по редким локализациям опухолей, любым возрастным группам и расчеты показателей выживаемости больных. БД ПРР насчитывает более 1 млн наблюдений, включает все рубрики и подрубрики МКБ-10 по II классу - коды С00-96. В работе представлена динамика заболеваемости и смертности населения СЗФО РФ в сравнении со среднероссийскими показателями, достоверность учета и выживаемость больных злокачественными новообразованиями. Установлено увеличение онкологической заболеваемости в СЗФО РФ за 8 лет на 10,4% в стандартизованных показателях и снижение смертности населения в СЗФО РФ на 11,4% в тех же показателях. Рассчитана динамика пятилетней наблюдаемой выживаемости больных СЗФО РФ с учетом возрастных групп. Надежность БД ПРР СЗФО РФ подтверждается тем, что материалы трех административных территорий после тщательной проверки включены в монографию МАИР «Рак на 5 континентах», том XI (Санкт-Петербург, Архангельская обл. и Республика Карелия). The completely formed database of the Population Cancer Registry (PCR database) of the North-Western Federal district of the Russian Federation in February 2019 has significantly expanded the ability to objectively assess the activities of the cancer service on a more reliable basis of analytical materials. In Russia, for the first time, it was possible to conduct epidemiological studies of malignant tumors for rare tumor locations, any age groups, and calculations of patient survival rates. The PCR database has more than 1 million observations and includes all the headings and subheadings of ICD-10 for class II - codes C00-96. The article will present the dynamics of morbidity and mortality of the population of the northwestern Federal district of the Russian Federation in comparison with the national average, the reliability of accounting and survival of patients with malignant tumors. For 8 years, the growth of cancer incidence in the Northwestern Federal district of the Russian Federation by 10,4 % in standardized indicators and a decrease in population mortality in the Northwestern Federal district of the Russian Federation by 11,4 % in the same indicators. The dynamics of the 5-year observed survival rate of patients with Northwestern Federal district of the Russian Federation, taking into account age groups, is calculated. The reliability of the PCR database of the Northwestern Federal district of the Russian Federation is confirmed by the fact that the materials of 3 administrative territories are included in the IARC monograph «Cancer incidence in five continents. Vol. XI» (Saint-Petersburg, Arkhangelsk region and the Republic of Karelia).

scholarly journals Dynamics of survival of patients with prostate cancer at the population level, taking into account the stage of the disease and place of residence

2021 ◽  
Vol 16 (4) ◽  
pp. 120-128
Author(s):  
R. D. Andreeva ◽  
R. S. Nizamova ◽  
A. A. Andreev
Keyword(s):  
Prostate Cancer ◽  
Comparative Analysis ◽  
Russian Federation ◽  
Rural Areas ◽  
Malignant Tumors ◽  
Survival Rates ◽  
Relative Survival ◽  
Urban Residents ◽  
Place Of Residence ◽  
The Russian Federation

Background. Prostate cancer (PCa) is rapidly gaining a leading position in the incidence of malignant tumors among men. With a general decrease in mortality from all oncological diseases, mortality from PCa in the Russian Federation is increasing: in 2005 there were 8192 deaths, in 2015 - 11987.Objective of the study. Calculation and assessment of survival rates for patients with PCa in the Samara region for the period from 2010 to 2016, taking into account the stage of the disease, the place of residence of patients, a comparative analysis of the observed, adjusted and relative 5-year survival for this disease in a number of regions of Russia and in the world.Materials and methods. The object of the study was all registered patients for the period 2010-2016, with the first established PCa.The calculation and analysis of the observed (OS), adjusted (AS) and relative (OS) survival of 7670 patients with PCa taking into account the stage of the disease and place of residence (urban residents — 6408people, rural — 1262), registered in the database of the population cancer registry of Samara Region Clinical Oncology Clinic. The start date of the study is January 1, 2010, the end date is December 31, 2019. The calculation of survival was carried out by the dynamic (actuarial) method.Results. When assessing the survival of patients with PCa, lower rates of observed survival were observed than adjusted, which indicates the presence of intercurrent causes of death.During the study period, an inverse dependence of survival on the prevalence of the tumor process was revealed. The level of observed survival and adjusted survival of all patients is associated in the survival range at stages II—III: 1-year-old observed survival — 89.1 % (adjusted survival — 92.3 %), 5-year-old observed survival — 62.6 % (adjusted survival — 76.6 %).The adjusted and relative survival rate for the urban population is higher than for the rural population, which may indicate an insufficient level of access to cancer care for patients with PCa in rural areas: the indicators of 1-year adjusted survival of urban residents are higher — 3.3 % (relative survival — 2.4 %), 5-year-old adjusted survival—7.4 % (relative survival — 10.3 %) than in patients registered in rural hospitals.Conclusion. A comparative analysis of indicators of 1- and 5-year survival of patients with PCa in the Samara region and a number of regions of the Russian Federation for 2006—2010 revealed that domestic indicators of 1-year and 5-year relative survival are slightly lower than the European average for 2000—2007. The range of indicators of the 5-year relative survivalfor 2010—2013 in the Samara region amounted to 82.2—93.1 %.

scholarly journals Epidemiology and survival rates of patients with malignant tumors in the Russian Federation

2021 ◽  
Author(s):  
Vakhtang M. Merabishvili
Keyword(s):  
Russian Federation ◽  
Cancer Incidence ◽  
Malignant Tumors ◽  
Survival Rates ◽  
Public Health Problem ◽  
Federal District ◽  
Cancer Registries ◽  
Population Based ◽  
Important Public Health Problem ◽  
The Russian Federation

Malignant tumors remain the most important public health problem in the world, being the second or even the leading cause of death in some countries. Cancer incidence is greatly influenced by the ever-increasing environmental hazards. Population-based Cancer Registries (PCRs) provide necessary data to monitor and assess cancer incidence. PCRs collect obligatory data on incidence rate with time series analysis, mortality and survival rates in patients diagnosed with malignant tumors. The study presents the results of the operation of PCRs as exemplified in the analysis of the PCR of Saint Petersburg and the Northwestern Federal District of the Russian Federation.

scholarly journals The state of cancer care in Russia: malignant tumors of the skin (C44). Prevalence, index of accuracy, localization and histological structure. Population-based research at the federal district level

2021 ◽  
Vol 67 (5) ◽  
pp. 635-639
Author(s):  
Vahtang Merabishvili
Keyword(s):  
Russian Federation ◽  
Kaposi's Sarcoma ◽  
Malignant Tumors ◽  
Kaposi’S Sarcoma ◽  
Federal District ◽  
Cancer Registries ◽  
Histological Structure ◽  
Visual Localization ◽  
Prevalence Index ◽  
The Russian Federation

Malignant tumors of the skin — visual localization, with a low mortality rate. Despite the fact that malignant tumors of the skin (C44) belong to the group of malignant tumors in many countries, cancer registries did not keep its records, the same attitude to this tumor was developed by doctors, which makes it difficult to conduct comparative studies between countries. When selecting data for the analysis of the prevalence of malignant tumors of the skin, in addition to the heading C44, a part of the heading ICD-10 — C46 — Kaposi's sarcoma — its part C46.0 — Kaposi's sarcoma of the skin is added. In many cases, it is not taken into account, due to its extremely rare occurrence, which does not have any practical impact on all the main analytical indicators. The purpose of this study is: for the first time in Russia, to consider not only the patterns of the prevalence of malignant tumors of the skin, but also to study the specifics of the localization and histological structure of this tumor localization, based on the newly created database of the population cancer Registry (PCR) of the North-Western Federal District of the Russian Federation (NWFD of the Russian Federation).

scholarly journals Staffing of outpatient departments of medical organizations by doctors of functional diagnostics in the Russian Federation, in 2012-2017

2019 ◽  
Vol 18 (1) ◽  
pp. 143-149
Author(s):  
D. A. Tolmachev ◽  
I. M. Son ◽  
M. A. Ivanova ◽  
N. M. Popova
Keyword(s):  
Russian Federation ◽  
Federal District ◽  
Descriptive Statistics ◽  
Positive Trend ◽  
Functional Diagnostics ◽  
Medical Organization ◽  
Federal Districts ◽  
Outpatient Departments ◽  
The Russian Federation ◽  
Almost All

Aim. To analyze the current situation in the staffing of functional diagnostics by doctors in the Russian Federation.Material and methods. The method of descriptive statistics was used to analyze the data of the Federal statistical observation № 30 “Information about the medical organization” on the staffing of doctors of functional diagnostics for the period from 2012 to 2017.Results. During the analyzed period, the staffing of doctors of functional diagnostics in the Russian was low, although there was a positive trend. In the calculation of staffing for the number of occupied positions in almost all Federal districts, parameter was higher than 80,0%, with the exception of the Southern Federal District (76,0%).Conclusion. The dynamics of the staffing parameter for the number of occupied positions was negative. 

scholarly journals Analysis of the results of epizootic monitoring of rabies in the Russian Federation in 2020

2021 ◽  
pp. 52-58
Author(s):  
V. V. Mikhailova ◽  
T. P. Lobova ◽  
M. S. Shishkina ◽  
A. N. Skvortsova ◽  
A. A. Varentsova
Keyword(s):  
Russian Federation ◽  
Prevention And Control ◽  
Federal District ◽  
Annual Reports ◽  
Economic Costs ◽  
The World ◽  
The Russian Federation ◽  
Almost All ◽  
And Control ◽  
Positive Results

Relevance. Currently, rabies is registered in almost all countries of the world and is included in the list of dangerous viral diseases. According to WHO estimates, more than 50,000 people die from hydrophobia in the world every year. The urgency of the problem is also associated with the huge economic costs of prevention and antiepizootic measures. Annual rabies monitoring is an important link in the chain of epizootic situation improvement. Based on its results, a further strategy for the prevention and control of rabies is being built.Methods. The assessment of the epizootic situation in the Russian Federation for rabies in 2020 was carried out based on the results of the analysis of data from annual reports in the 4-vet form provided by state veterinary laboratories to the FSBI CNMVL.Results. Annual rabies epizootic monitoring is carried out throughout the territory of the Russian Federation. In 2020, 1517 positive results were obtained. Of these, 47% of cases are in pets (dogs, cats), 43% — on wild animals, 9% — on agricultural animals. Unfavorable items were recorded in 61 constituent entities of the Russian Federation. The most tense epizootic situation has developed in the Central Federal District and the Privolzhskiy Federal District (603 and 505 positive cases respectively).

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