Laser thermotherapy or excision, what to offer to a patient with pilonidal disease?

Objective. To carry out a comparative analysis of the results of epithelial coccygeal course treatment using laser-induced interstitial thermotherapy LIT) under ultrasound control and traditional open excision. The high trauma rate of traditional operations in the epithelial coccygeal course ECC), the duration of hospital stay, pain syndrome force surgeons to search for new technologies in the treatment of this pathology. Materials and methods. A retrospective analysis of the treatment results of 369 patients with ECC who were admitted to the clinic for elective surgery in the period from 2009 to 2019 was carried out. There were 264 men 71.5 %) and 105 women 28.5 %). The mean age was 26.9 7.2 years. The patients were divided into 2 groups: 190 patients of the main group underwent surgery using a fiber-optic laser under ultrasound guidance, 179 patients of the comparison group underwent traditional radical excision of ECC with application of primary sutures or various types of plastic. Results. The severity of pain syndrome after surgery in patients of the main group was 1.7 0.6 points, in the comparison group 3.5 1.3 points by a five-point visual analogue scale VAS) for pain. The duration of inpatient treatment in the main group was 1.8 0.4 days, in the comparison group 11.5 1.7 days. Moreover, in 197 76.1 %) patients of the main group, the operation was performed on an outpatient basis. The restoration of working capacity in the main group occurred after 5.2 1.2 days, and in the comparison group after 17.4 2.8. After traditional operations, the relapse of the disease was noted in 11.7 %, and after laser treatment, slightly more than 12.1 %. Satisfaction with the results of treatment in the main group was noted in 95.1 %, and in the comparison group in 90 % of patients. Conclusions. The obtained results of treatment allow us to recommend the technique of interstitial laser obliteration of the coccygeal cyst under ultrasound navigation developed in the clinic for widespread use in practical work of surgeons.

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Experience of the usage of nabumetone in oncogynecologic patients

HEALTH OF WOMAN ◽

10.15574/hw.2017.119.118 ◽

2017 ◽

pp. 118-122

Author(s):

S.M. Kartashov ◽

◽

E.M. Oleshko ◽

Keyword(s):

Antioxidant Activity ◽

Postoperative Period ◽

Comparison Group ◽

Surgical Intervention ◽

Malonic Dialdehyde ◽

Pain Syndrome ◽

Main Group ◽

Narcotic Analgesics ◽

Diene Conjugates ◽

Results Of Treatment

Objective: to study the effect of nabumetone in oncogynecologic patients in the postoperative period. Materials and methods. There were examined 98 patients of 40-78 years old, who were divided into two groups: the main group - 58 patients, of which 37 - patients with endometrial cancer I-III and 21 - with ovarian cancer of II-IV stage (FIGO); The comparison group included 40 patients (17 and 23 patients respectively). All patients underwent surgical treatment. In the postoperative period, were used NSAIDs - nabumeton. Before the operation and on the 10th day of the postoperative period, the following parameters were studied: a clinical blood test, TNF-a, ceruloplasmin, diene conjugates (DC), malonic dialdehyde (MDA), antioxidant activity (AOA). The content of TNF-a, in the blood serum was determined by radioimmunological, and DC, MDA, AOA by biochemical method. Results. Established: the content of the leukocyte formula before the start of treatment in the compared groups did not reveal any significant differences. After surgical intervention, both groups showed an increase in the absolute values of all leukocyte fractions. The level of ceruloplasmin in the patients of the comparison group increased significantly in the postoperative period, and in the main group the parameters of ceruloplasmin did not differ significantly. The level of TNF-a in the pre- and postoperative period in the compared groups did not differ. On the 10th day of the postoperative period, it significantly increased in the comparison group, and when nabumetone was used during the postoperative period, the level of TNF-a did not increase. The initial indicators characterizing the processes of LPO and AOA in both groups did not differ significantly. Assessing the dynamics of indicators before and after the operation, it was noted that in patients in the blood, the level of DC in both the baseline and in the comparison group increased. The use of nabumethon led to a slight increase in DC. The maintenance MDA in the postoperative period has increased in both groups, however it is unreliable in comparison with parameters before surgical intervention. In the comparison group, after the treatment, the antioxidant defense was reliably reduced. In the main group, the use of nabumetone contributed to a smaller decrease in AOA. The use of nabumeton allowed abandoning of narcotic analgesics in earlier periods of the postoperative period. Conclusion. Use of nabumeton in the postoperative period allows to reduce the pain syndrome, the number of inflammatory complications; contributes to the normalization of LPO processes, inhibits the inhibition of the antioxidant system, which contributes to the reduction of endogenous intoxication and improves the results of treatment of oncogynecologic patients. Key words: nabumeton, oncogynecologic patients, anti-inflammatory action, tumor necrosis factor, ceruloplasmin, diene conjugates, malanialdehyde, antioxidant activity.

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Evaluation of effectiveness of thioctic acid use in combined therapy of angiodistonia and polyneuropathy syndrome

Perm Medical Journal ◽

10.17816/pmj37417-25 ◽

2020 ◽

Vol 37 (4) ◽

pp. 17-25

Author(s):

Natal'ja N. Malyutina ◽

Arina F. Bolotova ◽

Roman B. Eremeev ◽

Dmitriy Yu. Sosnin

Keyword(s):

Standard Therapy ◽

Comparison Group ◽

Combined Therapy ◽

Randomized Study ◽

Pain Syndrome ◽

Main Group ◽

Thioctic Acid ◽

Results Of Treatment ◽

Significant Difference ◽

Additional Therapy

Objective. The aim of the study was to investigate the effectiveness of the preparation of thioctic acid combined with standard therapy among patients with angiodistonic syndrome and vegetative-sensory polyneuropathy of the extremities due to the influence of general vibration. Materials and methods. A prospective randomized study of two groups of patients with vibration disease was conducted: the main group (n = 30) and the comparison group (n = 30). All patients received standard therapy, while the main group received additional therapy with octolipen (300 mg per os 2 times a day). Results. The results of questionnaires and objective examination of patients did not establish the occurrence of any side effects when including the drug in the therapy. The survey data proved statistically significant differences in the assessment of pain syndrome at rest and in the occurrence of night pains (p = 0.022). At the same time, when assessing the severity of paresthesia, no statistically significant difference was found between the groups (p = 0.5536). The therapy was accompanied by normalization of the antioxidant status (AOS) in both groups: in the main group, the median AOS increased by 1.342 times and in the comparison group by 1.267 times. In the statistical evaluation, the inclusion of thioctic acid in the treatment was accompanied by a statistically significant increase in the AOS not only with the initial data (p 0.00001), but also in comparison with the results of treatment of patients in the comparison group (p = 0.0387). The data from the reovasographic study also showed that the therapy was more effective with additional inclusion of thioctic acid drug to it. Conclusions. Thus, the data obtained justify the feasibility and effectiveness of using thioctic acid preparation in the treatment of angiodistonia and polyneuropathy syndromes.

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CURRENT ASPECTS OF DIAGNOSTICS AND TREATMENT OF ACUTE BILLARIAN PANCREATITIS

Medical Science of Ukraine (MSU) ◽

10.32345/2664-4738.3-4.2018.10 ◽

2018 ◽

Vol 14 (3-4) ◽

pp. 74-79

Author(s):

I.V. Kolosovych ◽

B.H. Bezrodnyi ◽

I.V. Hanol

Keyword(s):

Acute Pancreatitis ◽

Length Of Stay ◽

Comparison Group ◽

Abdominal Cavity ◽

Main Group ◽

Duct System ◽

Results Of Treatment ◽

Positive Clinical Effect ◽

Number Of Patients ◽

Comparative Group

Relevance. The article is devoted to the problem of diagnosis and treatment of acute biliary pancreatitis, which remains one of the most common surgical diseases of the abdominal cavity and accounts for 33.2% of the total number of patients with acute pancreatitis. Objective of the work is to improve the diagnosis and results of surgical treatment of patients with acute pancreatitis of biliary etiology. Materials and methods. The results of treatment of 264 patients with acute pancreatitis of biliary etiology are analyzed. Operative treatment was applied in 92 (34,8 %) patients: endoscopic operations were performed in 44 patients (16,7 %). Thus, in 10 (3,8 %) patients, endoscopic papilloprotectomy was performed with the auditory of the duct system and the extraction of concrements. In other cases, organo-preserving intervention was performed without disturbing the morphofunctional integrity of the sphincter apparatus of the duct system: the cannulation in 6 (2,3%) patients, mechanical (balloon) in 5 (1,9 %) cases, pharmacological (myogenic antispasmodic) dilatation of distal duct and a large duodenal papilla in 11 (4,2 %) patients. In residual choledocholithiasis, a technique of papillotomy under the control of choledochoscopy was proposed – 12 (4,54 %) patients. A comparative analysis of the effectiveness of the treatment of patients who used the "open" (comparative group) and noninvasive endoscopic interventions in the early disease (the main group) was performed. Results. So in the main group the length of stay in the hospital was 12±3,2 days, respectively, in the comparison group – 26±4,3 days. In 42 (95,4 %) patients who had undergone endoscopic surgery, a positive clinical effect, a rapid regress of the symptoms of acute pancreatitis was achieved. In two (4,5 %) patients in the main group, the course was complicated by the development of the abscess of the stuffing box, and puncture under ultrasound control was performed. In patients of the comparison group complications arose in 5 (41,6 %) patients, it is noteworthy that all of them had undergone operative interventions, which were limited only to the rehabilitation and drainage of the abdominal cavity, a stuffing box bag. The mortality rate among unopposed was 1,2 % (2 patients), and among the operated – 11,9 % (11 patients). Among prooperated patients who died, 81,8 % (9 people) were elderly patients. Conclusions. The use of minimally invasive endoscopic interventions in the early phase of the disease reduces the length of stay of patients in the hospital from 26±4,3 days (comparison group) to 12 3,2 days (main group) and the number of complications occurring by 37,1 % (P <0, 05). Application of the proposed method of papillotomy under the control of choledochoscopy makes it possible to reduce the risk of perforation of the wall of the duodenum with the development of peritonitis or retroperitoneal phlegmon by 1,2 % (P <0,05).

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Вплив лікувально-профілактичних заходів на показники ротової рідини та клінічний стан тканин пародонта у дітей 6–7 років, хворих на гінгівіт

CLINICAL DENTISTRY ◽

10.11603/2311-9624.2017.1.7642 ◽

2017 ◽

Author(s):

O. V. Avdeev ◽

Y. K. Zmarko ◽

A. B. Boykiv ◽

R. O. Drevnitska

Keyword(s):

Clinical Supervision ◽

Oral Fluid ◽

Urease Activity ◽

Comparison Group ◽

Local Therapy ◽

Main Group ◽

Control Group ◽

Results Of Treatment ◽

Comparative Group ◽

Anti Inflammatory

The high prevalence of inflammatory processes in the periodontitis of children, the ineffective effectiveness of preventive and curative measures can contribute to the development of generalized periodontitis, therefore it remains urgent to develop pathogenetic effects in the treatment of chronic catarrhal gingivitis.The aim of the study – a comparative assessment of the traditional treatment of chronic catarrhal gingivitis in children aged 6–7 years with therapy using an anti-inflammatory gel with neovitin.Materials and Methods. 61 children aged 6–7 years, suffering from chronic catarrhal gingivitis, were taken under clinical supervision and divided into groups: the main (30 children) and the comparative (31 children). All children underwent conventional therapy in accordance with the protocols for the provision of medical care – basic therapy. In the main group, for a month, pathogenetic agents were used: an anti-inflammatory gel with neovitin, hygiene products were recommended. In the comparative group, 3 % hydrogen peroxide solution was used for local therapy, for rinsing of the mouth (during the first week of treatment) – Rotokan, a therapeutic and prophylactic toothpaste.Examination and control examinations were carried out with the hygienic state of the mouth determined by the hygienic index of Yu. A. Fedorov and V. V. Volodkina, prevalence and intensity of the inflammatory process in the gums with the help of the Schiller-Pisarev test and the PMA index, oral fluid index (lysozyme content, formation of oxydradicals, urease activity, degree of dysbiosis, pH and viscosity).Results and Discussion. After the treatment, elimination of gum inflammation in patients of the main group was accompanied by a decrease in the PMA index by 3.8 times; formation of oxyradicals decreased in children of the main group by 6.35 %; in the comparative group – by 6.15 %. Urease activity decreased in children of the main group by 16.37 % (p<0.05), the viscosity of the oral fluid of children decreased in 2.65 times in the main group and in 2.13 times in the comparative group (p<0.05). The lysozyme content increased in children of the main group by 15.61 % (p<0.05) in the comparison group – by 9.63% (p<0.05). The treatment after 0.5 years caused an increase in the lysozyme content in the oral fluid of the children of the main group to the level of the control group. The degree of dysbiosis decreased in the main group, in the comparison group tended to increase.Conclusions. The use of the proposed therapy with gel with neovitin contributed to the best results of treatment: reducing the degree of inflammation of the gums, the number of visits to the doctor, improving the indices of nonspecific protection in the oral fluid of 6-7 years-old children and, to a greater extent, six months after the treatment.

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INFLUENCE OF THE COMPLEX CORRECTION TECHNIQUE TO STRENGTH OF THE QUADRICEPS FEMORIS MUSCLE OF PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME

Russian Journal of Physiotherapy Balneology and Rehabilitation ◽

10.18821/1681-3456-2018-17-2-72-75 ◽

2018 ◽

Vol 17 (2) ◽

pp. 72-75

Author(s):

Elena Sergeevna Prokhorova ◽

V. V Ar’kov ◽

M. R Makarova

Keyword(s):

Knee Joint ◽

Lower Limb ◽

Pain Syndrome ◽

Patellofemoral Pain Syndrome ◽

Patellofemoral Pain ◽

Quadriceps Femoris ◽

Main Group ◽

Lumbosacral Spine ◽

Outpatient Basis ◽

Correction Technique

In 40 patients with patellofemoral pain syndrome, before and after the course of treatment, the strength indices of the hip muscles were studied by isokinetic dynamometry, as well as the severity of the pain syndrome in the knee joint and the lumbosacral spine according to the visual analogue scale. The patients of the main group (n = 20) used the technique of complex correction of the pelvic region and lower limb, which was mainly aimed at stabilizing the lumbosacral spine. Patients of the control group (n = 20) performed therapeutic gymnastics aimed at training the muscles of only the interested lower limb. The treatment was performed on an outpatient basis daily for 21 days. After the course of treatment in patients of the main group, the strengths of the quadriceps femoris were significantly higher (p < 0.05), and the degree of pain in the knee joint and lumbar spine was significantly lower (p < 0.05). The obtained data confirm the necessity and expediency of including exercises for stabilization of the lumbosacral spine in the rehabilitation program for patients with patellofemoral pain syndrome.

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Surgical treatment of patients with osteoarthritis of the ankle joint

Kazan medical journal ◽

10.17816/kmj2142 ◽

2012 ◽

Vol 93 (1) ◽

pp. 38-43

Author(s):

Yu A Plakseychuk ◽

R Z Salikhov ◽

V V Soloviev

Keyword(s):

Surgical Treatment ◽

Ankle Joint ◽

Bone Grafting ◽

Comparison Group ◽

Functional Results ◽

Main Group ◽

Radiographic Evaluation ◽

Results Of Treatment ◽

Ilizarov Apparatus

Aim. To evaluate the results of treatment using the authors’ proposed method of arthrodesis of the ankle and subtalar joints, based on the combination of bone grafting with compression in the Ilizarov apparatus. Methods. Conducted was a clinical and radiographic evaluation of the results of arthrodesis in the Ilizarov apparatus in 286 patients with osteoarthritis of the ankle and subtalar joints (during the last 15 years). 36 (12.6%) patients (the main group) were operated on using the authors’ proposed technique. Results. Bone adhesion as a result of arthrodesis was achieved in all patients of the main group. Excellent functional results were achieved in 11 out of 36 patients (30.5%), good results - in 22 (61.1%) patients, satisfactory results - in 3 (8.4%) patients. Bone adhesion as a result of arthrodesis in 250 patients of the comparison group was achieved in 243 patients (97.2%). In this group excellent functional results were achieved in 76 out of 250 patients (30.4%), good results - in 145 (58%) patients, satisfactory results - in 21 (8.4%) patients, poor results - in 8 (3.2%) patients. Conclusion. The proposed method of biarticular arthrodesis makes it possible to improve the trophism of the arthrodesis zone, to conduct the correction of posttraumatic deformities in the region of the ankle and subtalar joints, provides a durable and solid bone ankylosis of the ankle and subtalar joints, and makes it possible to achieve adhesion even in severe forms of osteoarthritis of the ankle and subtalar joints.

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CLINICAL ASSESSMENT OF THE EFFECTIVENESS APPLICATION "BIOCERULIN" IN THE COMPLEX TREATMENT OF THE PATIENTS WITH ONTOGENIC FLAGMONS OF THE MAXILLOFACIAL AREA

Ukrainian Dental Almanac ◽

10.31718/2409-0255.4.2019.05 ◽

2019 ◽

pp. 29-32

Author(s):

D.V. Steblovskyi ◽

V.V. Bondarenko ◽

O.S. Ivanytska ◽

V.M. Skrypnyk ◽

I.O. Ivanytskyi

Keyword(s):

General Condition ◽

Inflammatory Process ◽

New Technologies ◽

Comparison Group ◽

Main Group ◽

The Body ◽

Steady Increase ◽

Complex Treatment ◽

Maxillofacial Region ◽

Traditional Therapy

Treatment of odontogenic phlegmon of the maxillofacial region remains an urgent problem of surgical dentistry due to the steady increase in their frequency, tendency to generalize the process and adverse effects. In this regard, there is a constant search for ways to improve the effectiveness of treatment of patients with odontogenic phlegmons of maxillofacial region. New technologies of drug treatment of this pathology are developed and put into practice. In recent years the attention of researchers in various conditions accompanied by the development of oxidative stress began to attract drugs that have antioxidant action, as it became known that the excess of reactive oxygen species in the regenerating wounds in the hearth of purulent inflammation affects the course of the course, wound healing. Interest in the treatment of various pathological conditions of the body is caused by the domestic antioxidant multifunctional enzyme "Bioceruline" which is composed of copper. In this regard, the purpose of our study was to evaluate the effectiveness of the use of "Biocerulin" in the complex treatment of patients with odontogenic phlegmon of maxillofacial region. The object of the clinical study was 45 patients with odontogenic phlegmons of the maxillofacial region from 18 to 55 years old, who were treated in the maxillofacial department of PU "Poltava M.V. Sklifosovskyi regional clinical hospital PRC». All patients were without somatic pathology in compensated clinical condition. Immediately after hospitalization, patients underwent an emergency opening of purulent lesion, revision and adequate drainage of the affected cellular spaces, removal of the "causal" tooth. The extent of surgery and the choice of optimal access depended on the location and prevalence of phlegmon. Depending on the treatment, patients were divided into comparison groups (22 patients) and the main group (23 patients). The traditional therapy was used in the comparison group. "Biocerulin"was prescribed for the patients of the main group in addition to the traditional therapy. Analysis of obtained data in the treatment of patients with phlegmon revealed that both groups of patients had clear differences in the clinical course of purulent-inflammatory process. On the 2nd day after the opening of the phlegmon theweakness, headache, and sleep disorders were noted in the most of the patients of the comparison group who received traditional therapy. Pain with varying degrees of intensity was present in all patients. Improvement of the general condition of patients of this group was noted not earlier than 3-5 days after surgery. The improvement of the general condition and reduction of pain, normalization or decrease in body temperature, the beginning of restoration of function of the jaw apparatuswere notedin patients of the main group on the background of the introduction of "Bioceruline" already on the 2-3rd day after surgery. Thus, on the basis of the conducted researches it is possible to conclude that the basic (traditional) conservative therapeutic measures used for patients of the comparison group are not effective enough for the relief of the local and general inflammatory process, which caused the prolonged nature of organ-specific and functional rehabilitation of patients as a whole. The use of "Bioceruline" in complex therapy of patients with odontogenicphlegmons of the maxillofacial regionprovides rapid and intensive recovery of the general condition of patients and accelerates reparative processes in the wound and shortens the treatment time via 1.4 bed-days.

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Intracavitary laser obliteration of Baker cyst under ultrasonic navigation

Vestnik of Experimental and Clinical Surgery ◽

10.18499/2070-478x-2018-11-4-256-263 ◽

2018 ◽

Vol 11 (4) ◽

pp. 256-263

Author(s):

Igor Viktorovich Krochek ◽

Sergey Vladimirovich Sergiyko ◽

Valeriy Alexeevich Privalov ◽

Igor Ivanovich Shumilin ◽

Yuliya Grigorievna Shekunova ◽

...

Keyword(s):

Pain Syndrome ◽

Main Group ◽

Hospital Treatment ◽

Control Group ◽

Radical Excision ◽

Treatment Results ◽

Baker’S Cyst ◽

Single Wave ◽

Cyst Excision ◽

Baker's Cyst

Relevance. Baker's cyst is the formation in the popliteal region, resulting from the accumulation of synovial fluid in the semimembranous bursa due to anastomosis between the joint cavity and the synovial bursa of the popliteal region. Trauma and/or some inflammatory diseases of the joints are the main causes of these cysts. Despite the success of endoscopic methods of treatment of this category of patients, the frequency of postoperative complications is 3-10%. The aim is to conduct a comparative analysis of the Baker's cysts treatment results using intracavitary laser obliteration and traditional cyst excision. Materials and methods. The treatment results of 39 patients with Baker cysts, who entered the clinic for the period from 2012 to 2017, are analyzed. Patients were divided into 2 representative groups. Ultrasound-guided intracavitary laser obliteration of Baker's cyst was performed in 24 (62%) patients of the main group. Traditional radical excision of all cyst elements with application of the primary suture was performed for 15 (38%) patients of the control group. A russian single-wave programmable three-mode laser scalpel LSP - "IRE-Polyus" was used in the work. Results. The patients of the main group had almost no pain syndrome, the duration of hospital treatment and rehabilitation were 4 times shorter than in the group of traditional operations (p≤0,05). Satisfaction with the laser treatment results of the patients from this group was 83.3%, while in the traditional treatment group - only 66.6%. Conclusion. The minimum number of the disease recurrences after ultrasonic-controlled intracavitary laser obliteration of Baker's cysts, the simplicity and low-traumatism of manipulation, the low level of complications, coupled with the high patient satisfaction with the treatment results, set apart this technology from traditional one, which allows recommending this method for wide application.

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LOW BACK PAIN SYNDROME, COMPARISON OF VIEWS ON THE PROBLEM

Health and Ecology Issues ◽

10.51523/2708-6011.2017-14-2-10 ◽

2017 ◽

pp. 43-48

Author(s):

A. I. Gamanovich ◽

B. V. Drivotinov

Keyword(s):

Low Back Pain ◽

Back Pain ◽

English Language ◽

Comparison Group ◽

Traditional Approach ◽

Pain Syndrome ◽

Main Group ◽

Low Back ◽

Lower Back

Objective: to compare the effectiveness of two approaches to the treatment of patients with low back pain syndrome: the traditional approach based on the classification of I.P.Antonov (1984) and more modern one based on the criteria of nonspecific pain. Material and methods. The work gives the data of complex examination and treatment of 628 patients of the main group and 79 patients of the comparison group. Results and discussion. Both the groups detected abnormalities from normal values with greater frequency in laboratory and tool methods of research. The duration of inpatient treatment of the patients of the main group was statistically significantly shorter due to a differentiated traditional approach to the treatment of patients with vertebrogenic lumbosacral pain syndrome. Conclusion. The traditional approach to the concretization of pain syndrome in lumbar osteochondrosis substantially in terms of effectiveness exceeds the concept of nonspecific pain in the lower back, references for which dominate in English-language sources.

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Dysplasia of the connective tissue is a factor, aggravating menstrual pain syndrome in adolescent girls

Journal of obstetrics and women s diseases ◽

10.17816/jowd67138-46 ◽

2018 ◽

Vol 67 (1) ◽

pp. 38-46

Author(s):

Valentina S. Orlova ◽

Oksana V. Trushina ◽

Irina V. Kalashnikova

Keyword(s):

Connective Tissue ◽

Emotional Disorders ◽

Adolescent Girls ◽

Comparison Group ◽

Clinical Signs ◽

Pain Syndrome ◽

Main Group ◽

Mcgill Pain Questionnaire ◽

Primary Dysmenorrhea ◽

Menstrual Pain

Background. Menstrual pain syndrome is accompanied by a complex of neurovegetative, metabolic-endocrine and psycho-emotional disorders. Dysplasia of connective tissue is characterized by a high level of functional disorders of the central and autonomic nervous system and emotional disorders. Aim. Detection of features of a clinical current of primary dysmenorrhea in adolescent girls with signs an undifferentiated dysplasia of connecting tissue (UDCT). Materials and methods. 210 adolescent girls at the age of 11–17 full years suffering primary dysmenorrhea were examined. Depending on the presence or absence of clinical signs of undifferentiated connective tissue, two groups were identified. The main group consisted of 120 patients, the comparison group comprised 90 patients. The severity of the menstrual pain syndrome was assessed using the three scales of the McGill Pain Questionnaire. For psychological testing was used a scale of self-assessment of anxiety of Ch.D. Spielberger – Yu.L. Khanina. Results. In 90.9 ± 2.6% of patients of the main group the debut of a dysmenorrhea has taken place in the period of formation of menstrual function — within the first 2 years after menarche. The average value of the rank index of pain in the main group was higher than in the comparison group (3.5 ± 0.1 and 2.8 ± 0.1, p < 0.001). In an internal picture of perception of pain at patients of the main group the emotional component prevailed. Their psychoemotional status was distinguished by a higher level of the average score of reactive (45.3 ± 0.9 and 36.3 ± 1.4; p < 0.001) and personal (49.9 ± 0.6 and 41.4 ± 1.0; p < 0.001) of anxiety. Conclusions. The obtained results give the grounds to consider the presence of clinical manifestations of an undifferentiated dysplasia of a connecting tissue in adolescent girls as a predictor, which is making heavier a clinical current of a menstrual pain syndrome.

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