Value of psychological adaptation of labor-intensive underground workers in formation of arterial hypertension regarding age aspect

Objective. To study the prerequisites for the development of hypertension based on the manifestation of psychovegetative dysfunction and some changes in the biochemical and functional parameters of CVS in the age aspect. Psychological adaptation of a group of underground miners in conditions of intensive labor was analyzed on the basis of indicators of psycho-vegetative status taking into account the influence of professional and psychosocial factors. In connection with the established diagnosis i.e. arterial hypertension (AH) syndrome, especially in middle-aged persons, it is of interest to study the indicators of psycho-vegetative status in the age aspect and to compare them with some changes in biochemical and functional state of cardiovascular system (CVS) in this contingent of patients. Materials and methods. The results of the study of psycho-vegetative status of 60 underground miners with AH syndrome (age 46.8 2.0 years, experience 22.0 2.4 years) using the method of psychophysiological testing as well as analysis of some clinical, functional and laboratory parameters are presented. Results. The adaptive psycho-vegetative phenotypes in a group of underground workers with AH syndrome in the age aspect were identified. Conclusions. With an increase in the length of service among labor-intensive workers, the characteristics of psycho-vegetative status change qualitatively in the form of elevated anxiety and neuro-psychical stress with a decrease in the function of attention combined with a negative relationship of these parameters with increasing age, that is accompanied by dysfunction of CVS; studying of this aspect allows identifying the prerequisites for the development of hypertension so as to form a risk group in time.

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State of cardiovascular system in employees with chronic obstructive pulmonary disease in combination with arterial hypertension in terms of exposure to toxic games

Perm Medical Journal ◽

10.17816/pmj38116-28 ◽

2021 ◽

Vol 38 (1) ◽

pp. 16-28

Author(s):

L. A. Panacheva ◽

L. A. Shpagina

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Arterial Hypertension ◽

Cardiovascular System ◽

Structure And Function ◽

Chronic Obstructive ◽

Length Of Service ◽

Obstructive Pulmonary Disease ◽

The Right ◽

And Function ◽

Large Vessels

Objective. Identification of the features of the cardiovascular system damage in chronic obstructive pulmonary disease (COPD) combined with arterial hypertension (AH) in workers exposed to toxic gases (TG). Materials and methods. 132 house painters and paint production workers of the Novosibirsk aviation enterprise were included in 3 strata and examined: I-COPD and TG; II-COPD in combination with AH when exposed to TG; III COPD in combination with AH without exposure to TG. Employees of all strata were divided by length of service less than 10 and more than 10 years. The selection of workers in groups was carried out by a continuous method. Results. The most pronounced changes on the ECG, regardless of the length of service, were observed in workers with COPD in combination with hypertension and contact with TG (levogram and metabolic changes in the myocardium). When exposed to TG for more than 10 years, hypertrophy of the left parts of the heart was also detected. Among workers with COPD in combination with hypertension exposed to TG, the indicators of average pulmonary artery pressure (APAP) and pulmonary vascular resistance (PVR) elevated with increasing work experience; changes in the structure and function of the right and left parts of the heart and signs of remodeling of large vessels were also revealed. The same workers showed more pronounced changes in the daily blood pressure profile (DBPP) of AP with the prevalence of Non-dippers and Night-pickers. Conclusions. Among workers suffering from comorbid pathology, with increasing duration of TG exposure over 10 years, there were observed the most pronounced ECG changes (deviation of electrical axis to the left, metabolic changes in the myocardium, hypertrophy of the left heart); increased APAP and PVR 1.21 and 1.10 times; changes in the structure and function of the right and left chambers of the heart, remodeling of large vessels; increase in the frequency of variants of the DBPP of Non-dippers and Night-pickers.

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PSYCHOVEGETATIVE PREREQUISITES FOR ARTERIAL HYPERTENSION SYNDROME INUNDERGROUND WORKERS

10.31089/978-5-6042929-2-1-2021-1-393-397 ◽

2021 ◽

Author(s):

S.V. Paramonova ◽

◽

N.N. Malyutina ◽

N.S. Sedinina

Keyword(s):

Arterial Hypertension ◽

Cardiovascular System ◽

Clinical Laboratory ◽

Vegetative State ◽

Negative Relationship ◽

Risk Groups ◽

Main Group ◽

Laboratory Diagnostics ◽

Aged People ◽

Age Related

Abstract: We examined 109 men working at а mining enterprise exposed to occupational and psychosocial factors. The patients were divided into two groups: the main group - 60 men working in underground conditions, the conditions are assigned to classes 3.3 - 3.4; comparison group - 49 men performing ground work, whose conditions are classified as 3.2. In connection with the established diagnosis of "Syndrome of arterial hypertension" in middle-aged people of the main group, it was divided into two subgroups in terms of age - people under 45 years old (n = 20, age 38.45 ± 2.95 years), and people older 45 years old (n = 40, age 50.90 ± 1.46 years.). Purpose: to study the prerequisites for the development of hypertension based on the psychovegetative status and some changes in the biochemical and functional indicators of the CVS, depending on the age-related changes in these indicators. Materials and methods: the patient underwent a study of the psycho-vegetative state with an assessment of the level of neuropsychic stress, personal and situational anxiety, attention function, subjective reflection of psycho-vegetative distress. The state of the cardiovascular system was investigated according to the results of functional and clinical laboratory diagnostics. Results: A decrease in attention, an increase in personal anxiety and an increase in the number of psychovegetative complaints were significantly more often detected in the group of patients with hypertension (OR 7.50; 95% CI 2.39-23.58; OR 11.06 95% - CI - 4.35 - 28.10; CI 22.50; 95% CI - 7.09 - 71.41). Adaptive psychovegetative phenotypes were distinguished in two subgroups. In patients over 45 years old, a negative relationship was established between age, experience and some parameters of psycho-vegetative status, as well as a direct relationship between these parameters and some indicators of homeostasis in the diagnosis of hypertension syndrome in 95% of patients in this subgroup. Conclusions: with an increase in age and experience, there is a transformation of the adaptive psychovegetative phenotype with an inversion of connections with psychovegetative parameters against the background of increased functional disorders of the cardiovascular system. Diagnostics of the transformation of this phenotype makes it possible to assess the risk of developing arterial hypertension and contributes to the prevention of hypertension by forming risk groups.

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Application of the heated oxygen-helium mixture in rehabilitation of military servicers with arterial hypertension at the ambulatory-polycinic stage

Russian Journal of Physiotherapy Balneology and Rehabilitation ◽

10.17816/1681-3456-2020-19-2-4 ◽

2020 ◽

Vol 19 (2) ◽

pp. 90-94

Author(s):

N. V. Bobkina

Keyword(s):

Nervous System ◽

Arterial Hypertension ◽

Cardiovascular System ◽

Military Personnel ◽

Well Being ◽

Professional Activity ◽

Group I ◽

Psychoemotional State ◽

Helium Mixture ◽

Vegetative Status

Background. The professional activity of military personnel is characterized by complexity, high requirements for the state of physical and mental health, therefore, maintaining health and professional longevity is a priority task for the law enforcement agencies of the Russian Federation. Aims. The purpose of the study was to evaluate the effectiveness of the use of heated oxygen-helium mixture (OHM) in the rehabilitation of military personnel with arterial hypertension at the outpatient stage. Methods. The study included 68 people aged 32 to 56 (43,7 4,1) years. The patients were divided into two groups: Group I (n = 33) practically healthy volunteers, Group II (n = 35) patients with a verified diagnosis: arterial hypertension of I and II degrees, low and medium risk, the duration of the disease ranged from 1,5 to 18 (6.3 1.3) years. All patients included in the study underwent a course of inhalation of a heated OHM (the temperature of the mixture in the mask was 50С). Breathing was carried out in a cyclic-fractionated mode: breathing with a mixture 5 minutes, then breathing with atmospheric air 5 minutes (one cycle), 3 cycles per procedure. The course of treatment consisted of 1 procedure per day for 10 days from the first day of the study. The clinical efficacy of restorative treatment was assessed in three stages before the start of therapy, after the 5th and 10th procedures according to the following indicators: assessment of vegetative status using indicators of heart rate variability; express diagnostics of the psychoemotional state using the SAN questionnaire (well-being, activity, mood); assessment of adaptation of the cardiovascular system to physical activity using Martine's test with 20 squats. Results. In the second group, positive dynamics was noted in the form of normalization of the autonomic status, an increase in the activity of the parasympathetic division of the autonomic nervous system (an increase in SDNN, RMSSD indicators to 55 [4868] and 40 [3851 msec, respectively), a decrease in the tone of the sympathetic nervous system (normalization of the coefficient vagosympathetic balance LF/HF up to 1.1 [0.741.5]). The indicators of the SAN questionnaire have increased, which indicates an improvement in the psychoemotional state of servicemen. Patients with arterial hypertension, had positive dynamics in the rate of adaptive processes of restoration of the cardiovascular system after exercise (recovery time is 3.0 0.5 after the course). Conclusions. The use of a course of inhalations of a heated oxygen-helium mixture in the rehabilitation of servicemen with arterial hypertension has demonstrated its effectiveness in normalizing the psychoemotional state and vegetative status. In order to prevent the progression of arterial hypertension, this method can be included in rehabilitation programs at the outpatient and polyclinic stage.

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Relationship of Organizational Citizenship Behavior and Production Deviance: Role of Perceived Organizational Politics

Pakistan Journal of Psychological Research ◽

10.33824/pjpr.2019.34.2.20 ◽

2019 ◽

Vol 34 (2) ◽

pp. 367-382

Author(s):

Irsa Fatima Makhdoom ◽

Mohsin Atta ◽

Najma Iqbal Malik

Keyword(s):

Organizational Citizenship ◽

Organizational Citizenship Behavior ◽

Negative Relationship ◽

Civic Virtue ◽

Organizational Politics ◽

Work Behavior ◽

Citizenship Behavior ◽

Production Deviance ◽

Relationship Of ◽

The Relationship

The present study was an endeavor to extend the literature of perceived organizational politics by examining its moderating role between the relationship of organizational citizenship behavior and production deviance. Organizational Citizenship Behavior Scale (Mackenzie, Podsakoff, & Paine, 1999), Production Deviance sub-scale of Counterproductive Work Behavior Checklist-32 (Spector et al., 2006), and Perception of Organizational Politics Scale (Kacmar & Carlson, 1997) were used in present study. Hierarchical regression analyses revealed that low levels of perceived organizational politics moderated the relationship between courtesy and production deviance by strengthening the negative relationship of these behaviors while perceived organizational politics did not act as a moderator for the relationship of civic virtue and conscientiousness with production deviance. High level of go-along-to-get-ahead as a moderator strengthened the relationship of civic virtue and conscientiousness with production deviance and its low level was found to be moderating the relationship between courtesy and production deviance. Future implications of the study were also discussed.

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Faculty Opinions recommendation of Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14239.471737 ◽

2006 ◽

Author(s):

Lars C Huber

Keyword(s):

Pulmonary Arterial Hypertension ◽

Arterial Hypertension ◽

Pulmonary Arterial ◽

Relationship Of

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Topography of the Anxious Self: Abnormal Rest-Task Modulation in Social Anxiety Disorder

The Neuroscientist ◽

10.1177/10738584211030497 ◽

2021 ◽

pp. 107385842110304

Author(s):

Lorenzo Lucherini Angeletti ◽

Andrea Scalabrini ◽

Valdo Ricca ◽

Georg Northoff

Keyword(s):

Anxiety Disorder ◽

Social Anxiety ◽

Social Anxiety Disorder ◽

Negative Relationship ◽

Social Self ◽

Unspecific Symptom ◽

Relationship Of ◽

Increased Activity ◽

State Feature ◽

And Task

Social anxiety disorder (SAD) is characterized by social anxiety/fear, self-attention, and interoception. Functional magnetic resonance imaging studies demonstrate increased activity during symptom-sensitive tasks in regions of the default-mode network (DMN), amygdala (AMG), and salience network (SN). What is the source of this task-unspecific symptom-sensitive hyperactivity in DMN? We address this question by probing SAD resting state (rs) changes in DMN including their relation to other regions as possible source of task-unspecific hyperactivity in the same regions. Our findings show the following: (1) rs-hypoconnectivity within-DMN regions; (2) rs-hyperconnectivity between DMN and AMG/SN; (3) task-evoked hyperactivity in the abnormal rs-regions of DMN and AMG/SN during different symptom-sensitive tasks; (4) negative relationship of rest and task changes in especially anterior DMN regions as their rs-hypoconnectivity is accompanied by task-unspecific hyperactivity; (5) abnormal top-down/bottom-up modulation between anterior DMN regions and AMG during rest and task. Findings demonstrate that rs-hypoconnectivity among DMN regions is negatively related to task-unspecific hyperactivity in DMN and AMG/SN. We propose a model of “Topography of the Anxious Self” in SAD (TAS-SAD). Abnormal DMN-AMG/SN topography during rest, as trait feature of an “unstable social self”, is abnormally aggravated during SAD-sensitive situations resulting in task-related hyperactivity in the same regions with an “anxious self” as state feature.

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Blood pressure level and laboratory indicators of disease severity in patients with arterial hypertension and COVID-19

European Journal of Preventive Cardiology ◽

10.1093/eurjpc/zwab061.166 ◽

2021 ◽

Vol 28 (Supplement_1) ◽

Author(s):

K Popov ◽

A Novitskiy ◽

Y Shvarts

Keyword(s):

Blood Pressure ◽

Multivariate Analysis ◽

Arterial Hypertension ◽

Negative Correlation ◽

Diastolic Pressure ◽

Negative Relationship ◽

Laboratory Parameters ◽

Acute Period ◽

Nonparametric Correlation ◽

The Relationship

Abstract Funding Acknowledgements Type of funding sources: None. Background. Many patients with COVID-19 suffer from arterial hypertension and have marked variations in blood pressure (BP) during the acute period of infection. The reasons for such changes are poorly understood. Purpose. To assess the relationship between the level of BP and the severity of changes in the main clinical and laboratory parameters in patients with arterial hypertension and with a moderate course of COVID-19 at the stage of the height of the disease. Materials and methods. The study included 86 hospitalized patients with verified coronavirus disease of moderate severity: 46 of them were male, the median age was 65 years. Patients received adequate hypertension therapy for a long time. After hospitalization, treatment was adjusted if necessary. The level of laboratory parameters in the acute period of the disease was determined, including the electrolytes, C-reactive protein (CRP), albumin, ferritin, general blood test, etc. BP measured daily. The relationship between laboratory parameters and BP level was evaluated by nonparametric correlation using the Spearman coefficient and multivariate analysis based on the "generalized nonlinear model". Results. In 67.44% of patients with hypertension, an elevated BP level (>140/90) was observed against the background of moderate COVID-19. There was a significant negative correlation between the levels of CRP and BP throughout the stay in the hospital, the most significant is the 5th day of hospitalization. At the same time, a slightly stronger relationship is observed with diastolic BP (r = -0.4425) than with systolic BP (r = -0.3525). A similar trend is observed in all BP measurements. Besides, a negative correlation was found between potassium levels and BP values. The strongest association of potassium levels is with systolic BP on the day of hospitalization (r = -0.4850) and diastolic pressure on the 1st day of hospitalization (r = -0.3561). Multivariate analysis confirmed independent and reliable "influence" of CRP (p = 0.00018) and potassium (p = 0.03921) as independent predictors of diastolic pressure. Conclusions. Most patients with hypertension and moderate COVID-19 have elevated BP levels. There is a statistically significant negative relationship between the values of BP and levels of CRP and potassium. The obtained data may correspond to the existing hypothesis about the significant role of the kinin–kallikrein system in the pathogenesis of COVID-19.

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