O olho, o narrador e o monstro

1989 ◽  
Vol 10 (1) ◽  
pp. 58
Author(s):  
Leopoldo Comitti
Keyword(s):  
Mary Shelley ◽  
Starting Point ◽  
The Fantastic

A reading of Mary Shelley's novel Frankenstein, under the perspective of the Fantastic and taking as a starting point psychoanalylic theories. Leitura do romance Frankenstein, de Mary Shelley, sob a perspectiva do Fantástico e a partir de um instrumental teórico da Psicanálise.

scholarly journals “Why do you write what isn’t true?”: Dostoevsky and the Fantastic Paradox

2011 ◽  
pp. 30
Author(s):  
Michael Hollington
Keyword(s):  
American Fiction ◽  
Don Juan ◽  
Essay Writing ◽  
Starting Point ◽  
The Face ◽  
The Fantastic ◽  
Contemporary Reality

In this paper, my starting point will be Philip Roth’s famous essay “Writing American Fiction,” in which he complains about the difficulty of writing novels in a country “where the actuality is constantly outdoing our talents.” I shall contend that this perception is not a new one, nor does it apply to American reality alone, and trace it back through a series of writers commenting on the difficulty of writing novels in the face of contemporary reality to its origins in Byron’s Don Juan: “For truth is always strange; stranger than fiction.” I shall argue that the aesthetics of “romantic realism,” as Donald Fanger labels it—the writing of Dickens, Dostoevsky, Balzac, Gogol, etc—directly addresses this paradox, and that this partly accounts for the differences between it and “classic realism.” My contention is that we mistake the nature of such writing if we judge it by the criteria of “classic realism”—and find it wanting, as is often the case.

scholarly journals The Metamorphosis of the Myth of Alchemy: Mary Shelley’s Frankenstein

2017 ◽  
Vol 15 (1) ◽  
pp. 108-127
Author(s):  
Asunción López-Varela Azcárate ◽  
Estefanía Saavedra
Keyword(s):  
Natural Science ◽  
Mary Shelley ◽  
Science And Technology ◽  
Empirical Science ◽  
William Godwin ◽  
The Novel ◽  
Romantic Period ◽  
Contemporary Science ◽  
Starting Point

This article takes as starting point the myth of alchemy in Mary Shelley´s Frankenstein or the Modern Prometheus, often interpreted as a warning of the risks and dangers of science and technology demonized in the form of the creature. Set in the Romantic period, the paper argues that the novel stages an ambiguous relationship between the advances in natural science and the philosophical and spiritual concerns that Mary Shelley inherited from her father, the philosopher William Godwin, which she discussed with her husband, the poet Percy B. Shelley. In the context of contemporary interdisciplinary discourses that contemplate ‘consilience’ between the humanities and the sciences, this paper offers a reading of Frankenstein and of Percy B. Shelley’s essay “A Defence of Poetry” as critical of empirical science in their ambiguous positioning with regards to alchemy and contemporary science. Furthermore, the research seeks to establish links with eco-cybernetic theories which bring to the fore a renewed interest on humanistic aspects.

scholarly journals Dr. Frankestein and the Birth of Horror

2021 ◽  
Vol 3 (3) ◽  
pp. 193-0
Author(s):  
Andrey Vaganov
Keyword(s):  
Molecular Biology ◽  
Genetic Engineering ◽  
Mary Shelley ◽  
Scientific Basis ◽  
Common Noun ◽  
Literary Genre ◽  
The Novel ◽  
Starting Point ◽  
The Common

In the spring of 1818, a novel was published in England, which became the starting point of a new literary genre. The name of the discovered type of literature is sci-fi horror. The creator of sci-fi horror – Mary Shelley – was at that time only 21 years old. Even the title of the novel became today the common noun is “Frankenstein, or Modern Prometheus”. “Archetype of horror”– this is how literary critics say about this work. The article attempts to prove and show that the entire plot of the novel is based on discoveries made at that time in the science of electrical phenomena. The article also tells about experiments with electricity, conducted by scientists in the 18th – early 19th centuries, and their perception by contemporaries. Thewhole structure, narrative of the novel, its rhetoric and even expressive artistic means are all works on the idea of bringing the natural-scientific basis under the absolutely seemingly fantastic plan. But, moreover, the novel can be viewed as a work of genius, foreseeing the emergence of what will be called molecular biology and genetic engineering.

Crystal structure images of large gold clusters and growing crystals by HRTEM

1984 ◽  
Vol 42 ◽  
pp. 428-429
Author(s):  
L.R. Wallenberg ◽  
J.-O. Bovin ◽  
G. Schmid
Keyword(s):  
Crystal Structure ◽  
Nucleation And Growth ◽  
Close Packing ◽  
Gold Clusters ◽  
Molecular Weight Determination ◽  
Growth Mechanisms ◽  
Starting Point ◽  
Different Types ◽  
Nucleation And Growth Mechanisms ◽  
Points Of View

Metallic clusters are interesting from various points of view, e.g. as a mean of spreading expensive catalysts on a support, or following heterogeneous and homogeneous catalytic events. It is also possible to study nucleation and growth mechanisms for crystals with the cluster as known starting point.Gold-clusters containing 55 atoms were manufactured by reducing (C6H5)3PAuCl with B2H6 in benzene. The chemical composition was found to be Au9.2[P(C6H5)3]2Cl. Molecular-weight determination by means of an ultracentrifuge gave the formula Au55[P(C6H5)3]Cl6 A model was proposed from Mössbauer spectra by Schmid et al. with cubic close-packing of the 55 gold atoms in a cubeoctahedron as shown in Fig 1. The cluster is almost completely isolated from the surroundings by the twelve triphenylphosphane groups situated in each corner, and the chlorine atoms on the centre of the 3x3 square surfaces. This gives four groups of gold atoms, depending on the different types of surrounding.

Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia

2019 ◽  
Vol 476 (24) ◽  
pp. 3687-3704 ◽  
Author(s):  
Aphrodite T. Choumessi ◽  
Manuel Johanns ◽  
Claire Beaufay ◽  
Marie-France Herent ◽  
Vincent Stroobant ◽  
...  
Keyword(s):  
Glucose Uptake ◽  
Human Cancer ◽  
Glucose Production ◽  
Liver Mitochondria ◽  
New Drugs ◽  
Structural Isomer ◽  
Rat Liver Mitochondria ◽  
Ionization Mass ◽  
Ampk Activation ◽  
Starting Point

Root extracts of a Cameroon medicinal plant, Dorstenia psilurus, were purified by screening for AMP-activated protein kinase (AMPK) activation in incubated mouse embryo fibroblasts (MEFs). Two isoprenylated flavones that activated AMPK were isolated. Compound 1 was identified as artelasticin by high-resolution electrospray ionization mass spectrometry and 2D-NMR while its structural isomer, compound 2, was isolated for the first time and differed only by the position of one double bond on one isoprenyl substituent. Treatment of MEFs with purified compound 1 or compound 2 led to rapid and robust AMPK activation at low micromolar concentrations and increased the intracellular AMP:ATP ratio. In oxygen consumption experiments on isolated rat liver mitochondria, compound 1 and compound 2 inhibited complex II of the electron transport chain and in freeze–thawed mitochondria succinate dehydrogenase was inhibited. In incubated rat skeletal muscles, both compounds activated AMPK and stimulated glucose uptake. Moreover, these effects were lost in muscles pre-incubated with AMPK inhibitor SBI-0206965, suggesting AMPK dependency. Incubation of mouse hepatocytes with compound 1 or compound 2 led to AMPK activation, but glucose production was decreased in hepatocytes from both wild-type and AMPKβ1−/− mice, suggesting that this effect was not AMPK-dependent. However, when administered intraperitoneally to high-fat diet-induced insulin-resistant mice, compound 1 and compound 2 had blood glucose-lowering effects. In addition, compound 1 and compound 2 reduced the viability of several human cancer cells in culture. The flavonoids we have identified could be a starting point for the development of new drugs to treat type 2 diabetes.

Overview of Current Approaches to Aural Rehabilitation for Adults With Cochlear Implants

2020 ◽  
Vol 5 (5) ◽  
pp. 1175-1187
Author(s):  
Rachel Glade ◽  
Erin Taylor ◽  
Deborah S. Culbertson ◽  
Christin Ray
Keyword(s):  
Health Care ◽  
Clinical Practice ◽  
Cochlear Implants ◽  
Practice Patterns ◽  
The United States ◽  
Care Providers ◽  
Aural Rehabilitation ◽  
Starting Point ◽  
Clinical Models ◽  
Hearing Health

Purpose This clinical focus article provides an overview of clinical models currently being used for the provision of comprehensive aural rehabilitation (AR) for adults with cochlear implants (CIs) in the Unites States. Method Clinical AR models utilized by hearing health care providers from nine clinics across the United States were discussed with regard to interprofessional AR practice patterns in the adult CI population. The clinical models were presented in the context of existing knowledge and gaps in the literature. Future directions were proposed for optimizing the provision of AR for the adult CI patient population. Findings/Conclusions There is a general agreement that AR is an integral part of hearing health care for adults with CIs. While the provision of AR is feasible in different clinical practice settings, service delivery models are variable across hearing health care professionals and settings. AR may include interprofessional collaboration among surgeons, audiologists, and speech-language pathologists with varying roles based on the characteristics of a particular setting. Despite various existing barriers, the clinical practice patterns identified here provide a starting point toward a more standard approach to comprehensive AR for adults with CIs.

Indirect Assessment of Attitudes with Response-Time-Based Measures

2006 ◽  
Vol 37 (3) ◽  
pp. 131-139 ◽  
Author(s):  
Juliane Degner ◽  
Dirk Wentura ◽  
Klaus Rothermund
Keyword(s):  
Social Cognitive ◽  
Incremental Validity ◽  
Self Report ◽  
Small Scale ◽  
Implicit Measures ◽  
Scale Theory ◽  
Starting Point ◽  
Self Reports ◽  
Predicting Behavior ◽  
Social Cognitive Theories

Abstract: We review research on response-latency based (“implicit”) measures of attitudes by examining what hopes and intentions researchers have associated with their usage. We identified the hopes of (1) gaining better measures of interindividual differences in attitudes as compared to self-report measures (quality hope); (2) better predicting behavior, or predicting other behaviors, as compared to self-reports (incremental validity hope); (3) linking social-cognitive theories more adequately to empirical research (theory-link hope). We argue that the third hope should be the starting point for using these measures. Any attempt to improve these measures should include the search for a small-scale theory that adequately explains the basic effects found with such a measure. To date, small-scale theories for different measures are not equally well developed.

The Solidarity of Distance1

2005 ◽  
Vol 36 (3) ◽  
pp. 103-115 ◽  
Author(s):  
Robert A. Wicklund
Keyword(s):  
Physical Contact ◽  
Emotional Distance ◽  
Starting Point ◽  
Shared Emotions ◽  
Common Goals ◽  
Full Interaction ◽  
The Individual ◽  
Social Incompetence

Abstract: Solidarity in the classic sense pertains to a cohesion among humans that entails physical contact, shared emotions, and common goals or projects. Characteristic cases are to be found among families, close friends, or co-workers. The present paper, in contrast, treats a phenomenon of the solidarity of distance, a solidarity based in fear of certain others and in incompetence to interact with them. The starting point for this analysis is the person who is motivated to interact with others who are unfamiliar or fear-provoking. Given that the fear and momentary social incompetence do not allow a full interaction to ensue, the individual will move toward solidarity with those others on a symbolic level. In this manner the motivation to approach the others is acted upon while physical and emotional distance is retained.

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