Influence of Drugs of Continuous Use on the Sensory Regulation of the Static Balance of  Elderly Regular Practitioners of the Pilates Method

AbstractThe combination of types of medications can compromise the regulation of body balance in older adults. This study evaluated the effect of continuous use drugs on the sensory regulation of static balance in elderly women who regularly practice the Pilates method with and without a history of falls and estimate the risk of falls in this population. Cross-sectional study, carried out with 94 women (67.12±4.74 years) practicing Pilates, divided into: non-fallers (n = 74) and fallers (n = 18). Sociodemographic data, comorbidities, medications, and Mini Mental State Examination (MMSE), Falls Efficacy Scale (FES), Confidence in Balance Scale (ABC) were applied. The examination of static balance was performed by the Clinical Test of Sensory Interaction and Balance (CTSIB). The risk of falling was analyzed using an adjusted multiple logistic regression model, while the effect of drugs on falls was estimated by binary regression, results were presented using the odds ratio (OR). The CTSIB test revealed Condition 4 (OR = 3.038; 95% CI = 1.321–15.674) and Condition 5 (OR = 5.542; 95% CI = 1.678–18.303) as predictors of falls. Drugs showing an effect on fall were β2 agonist associated with glucocorticoid (OR = 0.245; 95% CI = 1,233–2,400), thiazide diuretic (OR = 0.344; 95% CI = 1.122–2.234), statin (OR = 0.245; 95 % CI = 1,237–2,338), angiotensin II receptor antagonist (OR = 0,245; 95% CI = 1,236–2,339), beta blocker (OR = 0,245; 95% CI = 1,238–2,402) and anti-vertigo (OR = 0,245; 95 % CI = 1.230–2.399). Regardless of the history of falls, the risk of falling was present in older adult regular Pilates practitioners. Six different drugs for continuous use showed an effect on falls.Keyword: Accidental Falls. Aging. Women´s Health. Accident Consequences.ResumoA combinação de tipos de medicamentos pode comprometer a regulação do equilíbrio corporal de idosos. Este estudo avaliou o efeito de fármacos de uso contínuo sobre a regulação sensorial do equilíbrio estático de mulheres idosas praticantes regulares do método Pilates com e sem histórico de queda e estimar o risco de queda dessa população. Estudo transversal, realizado com 94 mulheres (67,12±4,74 anos) praticantes de Pilates, divididas em: não-caidoras (n=74) e caidoras (n=18). Foram coletados dados sociodemográfico, comorbidades, medicamentos, e aplicado Mini Exame do Estado Mental (MEEM), Falls Efficacy Scale (FES), Escala de Confiança no Equilíbrio (ABC). O exame do equilíbrio estático foi realizado pelo Clinical Test of Sensory Interaction and Balance (CTSIB). O risco de queda foi analisado pelo modelo de regressão logística múltipla ajustado, enquanto, que o efeito dos fármacos sobre queda foi estimado pela regressão binária, resultados foram apresentados pelo odds ratio (OR). O teste CTSIB revelou a Condição 4 (OR= 3,038; 95% IC= 1,321–15,674) e Condição 5 (OR= 5,542; 95% IC= 1,678–18,303) como previsora de quedas. As drogas que mostram efeito sobre queda foram agonista β2 associada com glicocorticóide (OR=0,245; 95% IC= 1,233–2,400), diurético tiazídico (OR=0,344; 95% IC=1,122–2,234), estatina (OR=0,245; 95% IC=1,237–2,338), antagonista do receptor de angiotensina II (OR=0,245; 95% IC=1,236–2,339), betabloqueador (OR=0,245; 95% IC=1,238–2,402) e antivertiginoso (OR=0,245; 95% IC=1,230–2,399). Independente do histórico de quedas, o risco de cair esteve presente em idosas praticantes regulares do Pilates. Seis diferentes medicamentos de uso contínuo mostraram efeito sobre queda. Palavras-chave: Acidentes por Quedas. Envelhecimento. Saúde da Mulher. Consequências de Acidentes.

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Avaliação da regulação sensorial do equilíbrio corporal e risco de queda de mulheres adultas e idosas fisicamente ativas

PAJAR - Pan-American Journal of Aging Research ◽

10.15448/2357-9641.2019.2.32683 ◽

2019 ◽

Vol 7 (2) ◽

pp. 32683

Author(s):

Marcelo De Maio Nascimento ◽

Hugo Daniel Gomez De Castro ◽

Mateus Alves Ramos

Keyword(s):

Elderly Women ◽

Dynamic Balance ◽

Age Groups ◽

Detailed Examination ◽

Adult Women ◽

Risk Of Falling ◽

Balance Test ◽

Cross Sectional ◽

Physically Active ◽

Sensory Regulation

OBJECTIVE: To examine the sensory performance of static and dynamic balance regulation and the risk of falling in physically active adult and elderly women.METHOD: This is a non-probabilistic and intentional cross-sectional study. Thirty four women (51.90±15.84 years) enrolled in a gym attended. The population evaluated was stratified in age groups: 20-59 years (n=18) and 60 69 years (n=16). The gait was evaluated by the Time Up and Go (TUGs), Time Up and Go manual (TUGm), and Time Up and Go cognitive (TUGc), the balance by the Dynamic Gait Index (DGI) and Body Balance Test (TEC). RESULTS: Student’s t-test showed significant differences between age groups for comorbidities: hearing, vision, vertigo, labyrinthitis (p≤0.05). Comparatively, adult women showed better performance indices than older women in physical tests. According to the standards of the tests, there was no risk of falling for any group. However, regardless of age, a detailed examination of the TEC test showed a deficit in the sensory regulation of the visual, vestibular and somatosensory systems of the static and dynamic balance of fallers and non fallers (p≤0.05). The logistic regression analysis indicated the interoceptive regulation of the dynamic balance as a predictor of fall (p≤0.05). CONCLUSION: Deficits in the vestibular and somatosensory systems gradually potentiate the risk of falls in adult and elderly women, even if they remain physically active.

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Rethinking the neurological examination I: static balance assessment

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2011000700021 ◽

2011 ◽

Vol 69 (6) ◽

pp. 954-958 ◽

Cited By ~ 5

Author(s):

Péricles A. Maranhão-Filho ◽

Eliana Teixeira Maranhão ◽

Marcos Martins da Silva ◽

Marco Antônio Lima

Keyword(s):

Elderly Patients ◽

Neurological Examination ◽

Sensory Integration ◽

Static Equilibrium ◽

Static Balance ◽

Clinical Test ◽

Balance Assessment ◽

Risk Of Falling ◽

Functional Reach ◽

Functional Reach Test

The authors advocate a modernization of the neurologic exam with regard to the evaluation of static equilibrium through the application of some easily performed and interpreted bedside maneuvers like the Clinical Test of Sensory Integration and Balance - modified and the Functional Reach Test. The authors also believe that these and other assessments, such as that of the risk of falling for elderly patients, should be incorporated into the routine neurological examination.

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Influence of gender on static balance in healthy community dwelling elderly: a comparison using posturography

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20203444 ◽

2020 ◽

Vol 8 (8) ◽

pp. 2950

Author(s):

Atiya A. Shaikh ◽

Rutuja D. Joshi

Keyword(s):

Community Dwelling ◽

P Value ◽

Static Balance ◽

Clinical Test ◽

Sensory Interaction ◽

Male And Female ◽

Eyes Closed ◽

Healthy Elderly ◽

Significant Difference ◽

Eyes Open

Background: Background and need of study- Influence of gender on balance is still controversial. Previous researchers have done studies using traditional methods. These methods may fail to detect subtle changes in balance difference. A tool like posturography which is highly specific may help to for accurate assessment and hence precise conclusion. Aim was to compare balance scores of male and female elderly using modified Clinical Test of Sensory Interaction on Balance (CTSIB).Methods: There were 56 healthy elderly ambulating without an assistive device and free from any neurological and orthopedic problems were assessed for their balance abilities using mCTSIB of balance master(standing on firm surface with eyes open, with eyes closed, standing on foam surface with eyes open and with eyes closed). Sway velocity was assessed using Unpaired t test.Results: There was a no significant difference in scores of modified CTSIB between male and female elderly ( p value>0.005).Conclusions: Gender has no effect on static balance abilities between male and female elderly while performing modified clinical test of sensory interaction on balance.

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Sensory interaction on static balance: A comparison concerning the history of falls of community-dwelling elderly

Geriatrics and Gerontology International ◽

10.1111/j.1447-0594.2009.00516.x ◽

2009 ◽

Vol 9 (2) ◽

pp. 165-171 ◽

Cited By ~ 32

Author(s):

Natalia Aquaroni Ricci ◽

Daniele de Faria Figueiredo Gonçalves ◽

Arlete Maria Valente Coimbra ◽

Ibsen Bellini Coimbra

Keyword(s):

Community Dwelling ◽

Static Balance ◽

Sensory Interaction ◽

History Of

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Investigation of static Balance control in 4-6 years old children with using the Pediatric Clinical Test of Sensory Interaction for Balance (P-CTSIB)

Iranian Rehabilitation Journal ◽

10.32598/irj.16.3.271 ◽

2018 ◽

Vol 16 (3) ◽

pp. 271-288

Author(s):

Nushin Sayadi ◽

Yones Lotfi ◽

Amir Hossein Kahlaee ◽

Parisa Jalilzadeh Afshari ◽

Enayatollah Bakhshi

Keyword(s):

Balance Control ◽

Static Balance ◽

Clinical Test ◽

Sensory Interaction

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Laboratory Evaluation and Clinical Characteristics of 2,132 Consecutive Unselected Patients with Venous Thromboembolism – Results of the Spanish Multicentric Study on Thrombophilia (EMET*-Study)

Thrombosis and Haemostasis ◽

10.1055/s-0038-1655986 ◽

1997 ◽

Vol 77 (03) ◽

pp. 444-451 ◽

Cited By ~ 163

Author(s):

José Mateo ◽

Artur Oliver ◽

Montserrat Borrell ◽

Núria Sala ◽

Jordi Fontcuberta ◽

...

Keyword(s):

Venous Thrombosis ◽

Odds Ratio ◽

Protein C ◽

Protein S ◽

Laboratory Evaluation ◽

Clinical Factors ◽

Recurrent Thrombosis ◽

Heparin Cofactor Ii ◽

Crude Odds Ratio ◽

History Of

SummaryPrevious studies on the prevalence of biological abnormalities causing venous thrombosis and the clinical characteristics of thrombotic patients are conflicting. We conducted a prospective study on 2,132 consecutive evaluable patients with venous thromboembolism to determine the prevalence of biological causes. Antithrombin, protein C, protein S, plasminogen and heparin cofactor-II deficiencies, dysfibrinoge-nemia, lupus anticoagulant and antiphospholipid antibodies were investigated. The risk of any of these alterations in patients with familial, recurrent, spontaneous or juvenile venous thrombosis was assessed. The overall prevalence of protein deficiencies was 12.85% (274/2,132) and antiphospholipid antibodies were found in 4.08% (87/2,132). Ten patients (0.47%) had antithrombin deficiency, 68 (3.19%) protein C deficiency, 155 (7.27%) protein S deficiency, 16 (0.75%) plasminogen deficiency, 8 (0.38%) heparin cofactor-II deficiency and 1 had dysfib-rinogenemia. Combined deficiencies were found in 16 cases (0.75%). A protein deficiency was found in 69 of 303 (22.8%) patients with a family history of thrombosis and in 205/1,829 (11.2%) without a history (crude odds ratio 2.34, 95% Cl 1.72-3.17); in 119/665 (17.9%) patients with thrombosis before the age of 45 and in 153/1,425 (10.7%) after the age of 45 (crude odds ratio 1.81, 95% Cl 1.40-2.35); in 103/616 (16.7%) with spontaneous thrombosis and in 171/1,516 (11.3%) with secondary thrombosis (crude odds ratio 1.58, 95% Cl 1.21-2.06); in 68/358 (19.0%) with recurrent thrombosis and in 206/1,774 (11.6%) with a single episode (crude odds ratio 1.78,95% Cl 1.32-2.41). Patients with combined clinical factors had a higher risk of carrying some deficiency. Biological causes of venous thrombosis can be identified in 16.93% of unselected patients. Family history of thrombosis, juvenile, spontaneous and recurrent thrombosis are the main clinical factors which enhance the risk of a deficiency. Laboratory evaluation of thrombotic patients is advisable, especially if some of these clinical factors are present.

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Incidence of elevated intraocular pressure after intravitreal injection in Japanese patients with age-related macular degeneration

Scientific Reports ◽

10.1038/s41598-021-91832-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Maiko Maruyama-Inoue ◽

Tatsuya Inoue ◽

Shaheeda Mohamed ◽

Yoko Kitajima ◽

Shoko Ikeda ◽

...

Keyword(s):

Risk Factors ◽

Intraocular Pressure ◽

Macular Degeneration ◽

Intravitreal Injection ◽

Odds Ratio ◽

Japanese Patients ◽

Age Related Macular Degeneration ◽

Age Related ◽

Elevated Intraocular Pressure ◽

History Of

AbstractThe purpose of this study was to report the incidence of elevated intraocular pressure (IOP) after intravitreal injection (IVI) of anti-vascular endothelial growth factor (VEGF) in Japanese patients with age-related macular degeneration (AMD). A retrospective study of chart review of patients who underwent ≥ 10 intravitreal anti-VEGF injections between April 2009 and December 2019 was conducted. Elevated IOP was defined as IOP ≥ 25 mmHg at one visit. Cases with elevated IOP resulting from IVI were identified. Furthermore, the association between elevated IOP and some parameters, as the risk factors that influence elevated IOP, was investigated. A total of 402 eyes of 370 patients were included in this study. Twenty-eight eyes of 26 patients (7.0%) were identified as cases with elevated IOP after IVI. The mean time of elevation after baseline was 50.6 ± 26.5 months. History of glaucoma (p = 0.021; odds ratio, 5.85), treatment modality (p = 0.019; odds ratio, 6.32), and total number of injections (p = 0.003; odds ratio, 1.03) were significantly associated with elevated IOP. A late complication of elevated IOP is associated with IVI in patients with AMD. Particularly, history of glaucoma and treat and extend regimen with frequent injections were found to be risk factors of elevated IOP.

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Concussion History and Balance Performance in Adolescent Rugby Union Players

The American Journal of Sports Medicine ◽

10.1177/0363546521998709 ◽

2021 ◽

pp. 036354652199870

Author(s):

Mark Matthews ◽

William Johnston ◽

Chris M. Bleakley ◽

Richard J. Davies ◽

Alan T. Rankin ◽

...

Keyword(s):

Dual Task ◽

Inertial Sensor ◽

Dynamic Balance ◽

Rugby Union ◽

Static Balance ◽

Balance Performance ◽

Eyes Closed ◽

History Of ◽

Concussion History ◽

Rugby Players

Background: Sports-related concussion is a worldwide problem. There is a concern that an initial concussion can cause prolonged subclinical disturbances to sensorimotor function that increase the risk of subsequent injury. The primary aim of this study was to examine whether a history of sports-related concussion has effects on static and dynamic balance performance in adolescent rugby players. Hypothesis: Dynamic balance would be worse in players with a history of concussion compared with those with no history of concussion. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Male adolescent rugby players aged 14 to 18 years from 5 schools were recruited before the start of the 2018-2019 playing season. Participants completed questionnaires and physical tests, including dynamic Y balance and single-leg static balance (eyes closed) tests, while performing single and dual tasks. Dynamic balance was assessed using inertial sensor instrumentation. Dependent variables were normalized reach distance and the sample entropy (SEn) of the 3 axes ( x, y, and z). Results: Of the 195 participants, 100 reported a history of concussion. Those with a history of concussion demonstrated higher SEn in all directions, with highest values during anterior (standardized mean difference [SMD], 0.4; 95% CI, 0.0-0.7; P = .027) and posteromedial (SMD, 0.5; 95% CI, 0.2-0.9; P = .004) reach directions compared with those with no history. There was no difference between groups (concussion history vs control) in traditional Y balance reach distances in the anterior or posteromedial directions or single-leg static balance during both single- ( P = .47) and dual-task ( P = .67) conditions. Conclusion: Adolescent rugby union athletes with a history of concussion had poorer dynamic balance during performance tasks compared with healthy controls. Static single-leg balance tests, either single or dual task, may not be sensitive enough to detect sensorimotor deficits in those with a history of concussion.

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Analysis of the relationship between periodontitis and osteoporosis/fractures: a cross-sectional study

BMC Oral Health ◽

10.1186/s12903-021-01496-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Seok-Jin Hong ◽

Byoung-Eun Yang ◽

Dae-Myoung Yoo ◽

Sung-Jae Kim ◽

Hyo-Geun Choi ◽

...

Keyword(s):

Odds Ratio ◽

Bone Destruction ◽

Epidemiological Data ◽

Income Group ◽

Cross Sectional Study ◽

Inflammatory Factors ◽

Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

History Of

Abstract Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. Methods This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. Results The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P < 0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46–1.62; P < 0.001). Conclusion Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.

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Knowledge, attitude, and practice of healthcare workers toward COVID-19 and its prevention in Ethiopia: A multicenter study

SAGE Open Medicine ◽

10.1177/20503121211034389 ◽

2021 ◽

Vol 9 ◽

pp. 205031212110343

Author(s):

Bedru Jemal ◽

Zemedu Aweke ◽

Simeneh Mola ◽

Sileshi Hailu ◽

Sileshi Abiy ◽

...

Keyword(s):

Social Media ◽

Confidence Interval ◽

Odds Ratio ◽

Healthcare Workers ◽

Medical Illness ◽

Chronic Medical Illness ◽

Attitude And Practice ◽

Route Of Transmission ◽

History Of ◽

Knowledge Attitude And Practice

Background: An emerging respiratory disease abbreviated as coronavirus disease 2019 was first reported in December 2019 in Wuhan city of China. The virus is zoonotic and tends to be transmitted between animals to humans and humans to humans. The major route of transmission of coronavirus disease 2019 is droplet and close contact. The Ethiopian Ministry of Health has initiated training for health care workers at a different level. Thus, the main objective of this study is to assess the knowledge, attitudes, and practices of health workers in Ethiopia toward coronavirus disease 2019 and its prevention techniques. Method: An institution-based multicenter cross-sectional study was conducted in each of eight teaching and referral hospitals. A total of 422 Ethiopian healthcare workers were selected for the assessment of knowledge, attitude, and practice toward coronavirus disease 2019. Data were collected using a structured questionnaire. A logistic regression model was used to identify factors associated with the attitude and knowledge of healthcare workers toward coronavirus disease 2019 at a significance level of p < 0.05. Result: Three hundred ninety-seven healthcare workers participated in the study, with a response rate of 94%. Among these, 88.2% and 94.7% of respondents had good knowledge and positive attitudes, respectively. A respondent with a history of chronic medical illness (odds ratio: 0.193, 95% confidence interval: 0.063–0.593), social media, telecommunication, and television/radio as a source of information were significantly associated with knowledge (odds ratio: 3.4, 95% confidence interval: 1.5–7.4, OR: 4.3, 95% confidence interval: 1.3–14.3 and odds ratio: 3.2, 95% confidence interval: 1.4–7.2). In addition, respondents with a history of chronic medical illness were significantly associated with a negative attitude toward coronavirus disease 2019. Conclusion: The knowledge and attitude were good while; the practice was relatively low. Sources of information such as social media, telecommunication, and television/radio were positively associated with healthcare workers' knowledge about coronavirus disease 2019.

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