scholarly journals Analysis of the relationship between periodontitis and osteoporosis/fractures: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Seok-Jin Hong ◽  
Byoung-Eun Yang ◽  
Dae-Myoung Yoo ◽  
Sung-Jae Kim ◽  
Hyo-Geun Choi ◽  
...  

Abstract Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. Methods This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. Results The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P < 0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46–1.62; P < 0.001). Conclusion Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Soo Hwan Byun ◽  
Dae Myoung Yoo ◽  
Minwook Chang ◽  
Hyo Geun Choi ◽  
Seok Jin Hong

The objective of this cross-sectional study was to evaluate the association between periodontitis and glaucoma. This prospective cohort study used epidemiological data from the Korean Genome and Epidemiology Study performed between 2004 and 2016. Among 173,209 participants, 9572 patients with periodontitis and 115,332 controls (nonperiodontitis) were selected. We analysed the history of glaucoma in periodontitis and control participants. The participants were interviewed regarding their history of hypertension, diabetes mellitus, hyperlipidaemia, periodontitis, glaucoma, smoking, and alcohol consumption by trained interviewers. A logistic regression model was created to analyse the odds ratio of having a history of glaucoma among patients with periodontitis. Two-tailed analyses using chi-square and independent t-tests were used for statistical analysis. The adjusted odds ratio of periodontitis as a risk factor for glaucoma was 3.44 (95% confidence interval = 2.99–3.97, p < 0.001 ). This study demonstrated that glaucoma was associated with periodontitis.


2013 ◽  
Vol 10 (1-2) ◽  
pp. 51-56 ◽  
Author(s):  
M. S. Rahman ◽  
S. Mithu ◽  
M. T. Islam ◽  
M. J. Uddin ◽  
R. R. Sarker ◽  
...  

Brucellosis is an important bacterial zoonotic disease causing significant economic loss in dairy industries worldwide including Bangladesh. But limited studies are devoted to determine the prevalence of brucellosis in goat in all districts of Bangladesh. Therefore, a cross-sectional study was undertaken to determine the seroprevalence of brucellosis in Black Bengal goats in Nilphamari Sadar and Kishoreganj upazillas of Nilphamari district of Bangladesh using Rose Bengal Test (RBT) as screening test and I-ELISA as confirmatory test. A total of 154 sera samples from Black Bengal goats were collected from Nilphamari district. Epidemiological data on the selected Black Bengal goats were collected using a structured questionnaire. The overall seroprevalence of brucellosis was found to be 2.59% in Black Bengal goats. A significantly (p<0.01) higher prevalence of brucellosis was found in Black Bengal goats with the history of previous abortion (33.33%). An insignificant (p>0.05) but higher prevalence of brucellosis was found in adult Black Bengal goats (>24 months) than young. The prevalence was relatively higher in cross-bred than pure Black Bengal goats, in female than male and in pregnant than non-pregnant Black Bengal goats. The result of the study will provide baseline data for control of brucellosis in goat in Bangladesh.DOI: http://dx.doi.org/10.3329/bjvm.v10i1-2.15646


2020 ◽  
Vol 11 ◽  
pp. 215145932093857
Author(s):  
Dong Min Kim ◽  
Dongjun Park ◽  
Hyojune Kim ◽  
Eui-Sup Lee ◽  
Myung Jin Shin ◽  
...  

Introduction: The aims of this study were to investigate (1) whether demographic factors would be risk factors for severe proximal humerus fracture (PHF), (2) relationship of radiological parameters with bone mineral density (BMD), deltoid tuberosity index (DTI), or severe PHF, and (3) correlation between DTI and BMD. Methods: We conducted a cross-sectional study based on radiographs and medical records taken during admission or the visit to the orthopedic clinic. We reviewed consecutive 100 adult patients who were diagnosed with PHF in our hospital from March 2014 to December 2016. Three- and 4-part fractures were regarded as severe PHFs. Univariable and multivariable logistic regression analyses were performed to evaluate risk factors for severe PHF. Also, we investigated the correlation between BMD and DTI using the additional BMD data of the patients who underwent shoulder surgeries. Results: This study included 62 nonsevere PHFs and 38 severe PHFs. There were 30 male and 70 female patients with a mean age of 66.4 ± 16.4 years. Mean T score of BMD was −2.5 ± 0.9 at the time of injury. Logistic regression analyses showed that age (odds ratio: 1.044, range: 1.011-1.079, P = .009) and sex (odds ratio of females: 3.763, range: 1.236-11.459, P = .020) were related to severe PHF. The group satisfying the radiological parameter criteria had significantly higher rates of severe PHF. The correlation coefficient (r) between DTI and T score was 0.555 ( P < .001). Discussion and Conclusion: Older age and female were the independent risk factors for severe PHF. Conversely, BMD and other medical comorbidities were not risk factors for severe PHF. Deltoid tuberosity index showed significantly high intraclass correlation coefficient and a strong correlation with the T score of BMD. Therefore, DTI may be useful for screening osteoporosis in PHF patients. Level of Evidence: Level IV, Cross-sectional study.


Author(s):  
Zumrotus Sholichah ◽  
Bondan Fajar Wahyudi ◽  
Corry Laura Junita Sianturi ◽  
Novia Tri Astuti

In 2017 leptospirosis cases occur in new areas in Bantul where cases have never been previously reported. Cases still occur in 2018 with an interval of two months after the first case. Preventive and curative efforts in the context of controlling cases have been carried out by the local health office, in addition to these control efforts, it is also necessary to know the presence of Leptospira in rats and water bodies in the area as well as the history of patients transmission. This study was conducted to provide epidemiological data, especially the status of Leptospira in rats as reservoir animal and water bodies as well as a history of patient activity as basic data for leptospirosis control in Gilangharjo Village.  This cross-sectional study was conducted at the case location in RT 03 Jodog, Gilangharjo Village, Pandak District, Bantul Regency, which was conducted in April 2018. Leptospira infection status was carried out on rats and water bodies by molecular examination, while the history of transmission based on interviews with patients and the result of the examination of Leptospira status. Rat species caught were dominated by R.tanezumi, R. norvegicus and B. indica. Positive rat infected with Leptospira were found in B. indica while in water bodies Leptospira contamination was not found. Infected rat can be a source of transmission for humans and other animals. Most of the patient's activities were carried out in the fields and at home, all of the patients had wounds that were not treated, and had a history of contact with rats that might transmit Leptospira to humans.


Author(s):  
Soo-Hwan Byun ◽  
Dae-Myoung Yoo ◽  
Jung-Woo Lee ◽  
Hyo-Geun Choi

Hyperuricemia arises from the buildup of excessive uric acid in the blood, and it is implicated in the development of periodontitis. The objective of this study was to investigate the association between hyperuricemia and periodontitis using a cross-sectional study design and Korean Genome and Epidemiology Study Health Examinee (KoGES HEXA) data. This prospective cohort study used epidemiological data from the KoGES from 2004 to 2016. Among 173,209 participants, 8809 with hyperuricemia and 126,465 controls (non-hyperuricemia) were selected. This study defined hyperuricemia as >7.0 mg/dL of uric acid in men and >6.0 mg/dL in women. This study analyzed the history of periodontitis among hyperuricemia and control participants. Participants’ age, gender, income, obesity, smoking, alcohol consumption, and nutritional intake were all examined. Chi-square tests, independent t-tests, and two-tailed analyses were used for statistical analysis. The adjusted OR (aOR) of hyperuricemia for periodontitis was 0.89 (95% confidence interval (CI) = 0.81–0.96, p = 0.005). This study demonstrated that hyperuricemia was associated with periodontitis. This finding meant that elevated uric acid levels could have a positive effect on periodontitis. However, further studies should be performed to determine the range of uric acid levels beneficial to periodontal health.


2021 ◽  
Author(s):  
Kaleab Berhanu ◽  
Yohannes Gebreegziabhere Haile ◽  
Asnake Limenhe ◽  
Kassahun Habatmu ◽  
Atalay Alem

Abstract Background Cathine and cathinone which are the main psychostimulant components of khat, a green leaf chewed by many people in Yemen and East Africa for recreational purposes are controlled drugs by the UN, but khat chewing is legal in those countries. There are reports on the prevalence of khat use and its association with some health problems and alteration of behavior in communities of those countries. However, there is lack of evidence on the prevalence and associated factors of problematic khat use (PKU) among prisoners. This study aimed to assess the prevalence and associated factors of PKU among prisoners of Debre Berhan prison in Ethiopia. Methods A cross-sectional study was conducted to assess history of PKU among prisoners before imprisonment at Debre Berhan prison. Randomly selected 347 prisoners were interviewed using Drug Abuse Screening Test (DAST) to screen for PKU in May 2017. Data were entered using Epi-Data version 3.1 and analyzed using Stata version 13 software. Bivariate and multivariable binary logistic regressions were conducted. Crude odds ratio and adjusted odds ratio (AOR), with 95% confidence interval (CI), are reported. Variables with p-value of < 0.05 were reported to be significantly associated with PKU. Results About one-third (28.5%) of the prisoners had PKU before imprisonment. Factors significantly associated with increased odds of PKU included being non-Orthodox Christian in religion (AOR = 18.1; 95% CI= (3.8, 85.8)), infrequent visit to worship place irrespective of religion (AOR = 2.9; 95% CI= (1.1, 7.9)), being urban resident (AOR = 22.0; 95% CI= (7.7, 62.9)), perception that the current offence is related to using the substance (AOR = 6.0; 95% CI= (2.8, 12.8)), family history of substance use (AOR = 4.1; 95% CI= (1.2, 14.6)), and living alone before imprisonment (AOR = 3.55; 95% CI= (1.2, 10.7)). Whereas, being married was significantly associated with lower odds of PKU (AOR = 0.3; 95% CI= (0.0, 0.8)). Conclusion Higher prevalence of PKU before imprisonment is reported in this population. In addition to other socio-demographic factors that showed association with use of the substance, current offence that led to imprisonment was also perceived as related to PKU. To prevent crime and health-related consequences of PKU in the community integrated action is recommended.


Author(s):  
Femmy N Akbar ◽  
Francisca A Tjakradidjaja ◽  
Hari Hendarto ◽  
Sayid Ridho ◽  
Nursyahidah ◽  
...  

Objectives: The morbidity and mortality rate of peptic ulcer disease (PUD) is quite high. For example proportion of PUD in China was 17.2%. There is a lack of epidemiological data available for this disease in Indonesia. This study aims to determine the proportion of PUD in Haji Hospital Jakarta and to describe the risk factors of age, sex, and patient history of NSAIDs medication.Materials and Methods: This was a cross sectional study. Samples were patients who undergo esophagogastroduodenoscopy (EGD) examinations at the Hajj Hospital Jakarta from 2015 until 2018. Samples who met the inclusion dan exclusion criteria were selected randomly as needed. Data of chief complaints, diagnosis, age, sex, and history of NSAIDs medication were taken from the medical record.Result and Discussions: 112 samples were selected in this study. Major chief complaint was dyspepsia (42.9%). The proportion of PUD was 16 (14.3%) and predominantly male (75%). Most of the samples with PUD were >46 years old (68.8%). History of NSAIDs medications were 81.3% and most commonly used was mefenamic acid (41.2%). There was no significant association between PUD with sex (p>0.005), but there was a significant association between PUD and age (p < 0.005). Furthermore, older people more than 46 years were 11.5 times more likely to develop peptic ulceration than below 46 years (PR= 11.556).Conclusion: Elderly people should be more aware of the risk of getting PUD, especially those who had a history of NSAIDs medication.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 27-30


2014 ◽  
Vol 31 (1) ◽  
pp. 42-49 ◽  
Author(s):  
V Crebassa ◽  
T Roucaute ◽  
JJ Guex ◽  
FA Allaert

Objective To evaluate the heredity factor of the chronic venous disorders and odds ratio linked to maternal or paternal heredity. Methods Cross-sectional epidemiological study conducted in daily practice of medical practitioners on all patients consulting them. The practitioners described the venous status of all patients consulting them and recorded the familial past history of venous disease. Results Among 21319 patients, 60.4% have a familial history of chronic venous disorder: unilateral paternal 7.5%, unilateral maternal 40.9% and bilateral: 12.0%. Chronic venous disorder prevalence is 58.8% in the global population, 38.2% in the absence of parental history, 67.0% for unilateral paternal, 71.3% for unilateral maternal and 79.2% for bilateral ( p < 0.0001). After adjustment on age and sex, results show significant ( p < 0.0001) odds ratio of 3.2 for unilateral paternal, of 3.4 for unilateral maternal and of 5.6 for a history in both parents. In the context of a history in both parents, the odds ratio increased to 5.6 for women and 8.4 for men. Conclusion This large cross-sectional study confirms the association between heredity and venous disease, but its results could call into question the maternal predominant character of the chronic venous disorder heredity.


BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e029946 ◽  
Author(s):  
Meng Zhang ◽  
Lijuan Bai ◽  
Jing Kang ◽  
Jing Ge ◽  
Wen Peng

ObjectivesTo explore whether bone mineral density (BMD) is associated with arterial stiffness in middle-aged and elderly people with an advanced arterial stiffness index as indicated by the cardio-ankle vascular index (CAVI).DesignA cross-sectional study.SettingThis study was conducted from September 2015 to May 2017 at the geriatrics department of a provincial medical centre in China.ParticipantsA total of 580 patients aged 50 and over were enrolled in the study. The mean age of the group was 64.82±11.4 years, and 63.1% were male.Primary outcome measuresAssociations of age with CAVI values and BMD. Associations between BMD and CAVI values.ResultsWith increasing age, CAVI values gradually increased (p<0.001) and the femoral neck (FN) and total hip (TH) BMD gradually decreased (p<0.001, all). In the bivariate correlation analyses between the covariates and CAVI values, age and CAVI values showed the greatest positive correlation (r=0.631, p<0.001), and CAVI values were negatively correlated with FN BMD (r=−0.229, p<0.001) and TH BMD (r=−0.218, p<0.001). In the linear regression analyses, TH BMD (B=−1.812 (95% CI −2.475 to −1.149), p<0.001) and FN BMD (B=−1.968 (95% CI −2.651 to −1.284), p<0.001) were negatively correlated with CAVI values. After adjusting for age, gender, body mass index, smoking, history of cardiovascular or cerebrovascular disease, history of diabetes mellitus, systolic blood pressure, high-density lipoprotein cholesterol, blood uric acid, fibrinogen and estimated glomerular filtration rate, only TH BMD was still negatively correlated with CAVI values (B=−0.843 (95%CI −1.454 to −0.232), p=0.007). However, there was no consistent and significant correlation between lumbar spine BMD and CAVI values.ConclusionIn this cross-sectional study, a significant correlation between TH BMD and CAVI values was observed in middle-aged and elderly Chinese inpatients. However, our cohort was a small sample of inpatients, and prospective studies from more centres are expected.


1970 ◽  
Vol 20 (1) ◽  
pp. 20-24
Author(s):  
MH Sardar ◽  
MAR Howlader ◽  
MU Mallik ◽  
AM Appolo ◽  
MS Islam ◽  
...  

A prospective cross sectional study was designed to assess the patterns of adult-onset epilepsy and determine the types of epilepsy which develop after complex febrile convulsion (CFC) and find out the causes of epilepsy, from January to December 2008, in Epilepsy Clinic of the Department of Neurology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. 106 consecutive adult (age>13 years) patients with adult-onset epilepsy receiving treatment from Epilepsy Clinic of the Department of Neurology of BSMMU, Dhaka, were the sample of this study. Records of these patients were reviewed & the patients & their family members were interviewed to assess the medical history. The data obtained from the records and the interviews formed the basis of this study. Chi-Square test was applied to analysis the data. Interviewed results and records of 106 patients were analyzed. Of the 106 patients with adult- onset epilepsy, the epilepsy categories [median age: 20 years, range: 14-46 years] were: generalized epilepsies in 51 (54.06%), partial epilepsies in 45 (47.7%), & undetermined epilepsies in 10 (10.6%) Thirty one (32.86%) of the 106 patients had history of CFC in the childhood (71% male, 29% female). Partial epilepsies were significantly associated with history of CFC [Odds Ratio: 3.29; (95% CI 1.30-8.06), (c2=5.49, df=1, p=0.012)] when compared to other epilepsies and epilepsy syndromes. An initial unprovoked simple partial seizure was also significantly associated with a positive history of CFC [Odds Ratio: 8.05; (95% CI 2.88-22.45), (c2=15.86, df=1, p<0.001)]. Generalized epilepsies are more common than partial epilepsies. Partial epilepsies seem to be associated with a history of CFC in childhood. The mechanism & pathophysiology of association between CFC and epilepsy in affected probands requires further investigations. Identification of the basic defect in relation to CFC & epilepsy may have important implication for the prevention of adult- onset epilepsy in patients with history of CFC. But the risk of epilepsy after febrile convulsions is much less than reported in many hospital studies & if febrile convulsion causes brain damage that leads to later epilepsy, this is a rare occurrence. Keywords: Generalized epilepsy; partial epilepsy; febrile convulsion; afebrile seizures; genetic. DOI: http://dx.doi.org/10.3329/jdmc.v20i1.8567 J Dhaka Med Coll. 2011; 20(1) :20-24


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