scholarly journals Drug price control order: the impact on pharmacoeconomics

2019 ◽  
Vol 8 (10) ◽  
pp. 2220
Author(s):  
Suchi M. Shah ◽  
Anil P. Singh ◽  
Parth K. Vachhani
Keyword(s):  
Drug Therapy ◽  
Drug Price ◽  
Price Control ◽  
Medical Specialties ◽  
Retail Prices ◽  
The Difference ◽  
Control Order ◽  
Microsoft Office ◽  
The Cost ◽  
The Impact

Background: The objective of the present study was to analyze the prices of metformin, losartan, atorvastatin, paracetamol and aspirin for the doses which are included in the list of Drug Price Control Order (DPCO) 2013.Methods: Current index medical specialties India, 37th year, April-July 2015 issue was used for analysis. The retail prices of the drugs in INR were tabulated in Microsoft Office Excel 2013. The prices of the above listed drugs were compared with prices of DPCO 2013 for the same doses of drugs. The analysis of drugs costing more than the prices listed in the DPCO with the margin of the difference in percentage was carried out.Results: Out of 25 brands of metformin 500 mg tablet, 11 (44%) brands had price higher than listed in DPCO 2013. Similarly, prices for losartan 25 mg and 50 mg tablets, 8 (25%) out of 32 and 11 (31.42%) out of 35 were higher respectively. For atorvastatin 5 mg and 10 mg tablets, 2 (9.52%) out of 21 and 8 (13.55%) out of 59 brands had higher prices. For paracetamol 500 mg tablet, 12 (63.15%) out of 19 brands were priced higher than DPCO list. For aspirin 100 mg tablet and 325 mg tablet, 3 (100%) out of 3 brands and 1 (100%) out of 1 brand had higher prices.Conclusions: Many of the brand formulations have higher prices than the DPCO 2013 issued by government of India. The clinicians prescribing these drugs should be aware of these brand formulations to reduce the cost of the drug therapy.

scholarly journals Cost variation analysis of ACE inhibitors in India

2017 ◽  
Vol 6 (6) ◽  
pp. 1522
Author(s):  
Prashant Wadagbalkar ◽  
Poonam Patel ◽  
Swati V. Raipurkar
Keyword(s):  
Ace Inhibitors ◽  
Antihypertensive Drugs ◽  
Patient Adherence ◽  
Antihypertensive Agents ◽  
Cost Ratio ◽  
Medical Specialties ◽  
Single Drug ◽  
Cost Variation ◽  
The Difference ◽  
The Cost

Background: Cardiovascular diseases are the most prevalent cause of death and disability in developed and developing countries. There is a wide variation in the prices of antihypertensive drugs marketed in India. Thus, a study was planned to find out variation in cost in the ACE Inhibitors available in India either as a single drug or in combination and to evaluate the difference in cost of various brands of the same ACE Inhibitors and ARBs by calculating percentage variation in cost in Indian rupees.Methods: Minimum and maximum costs in rupees (INR) of antihypertensive agents manufactured by different companies, in the same strength and dosage forms were obtained from “current index of medical specialties” January April 2016 and Drug Today October-December 2016. The cost ratio and percentage cost variation were calculated for each generic antihypertensive agent (ACE Inhibitors and ARBs).Results: This study shows that there is a wide variation in the prices of different brands of same ACE Inhibitors and ARBs in Indian market.Highest cost variation 400% is for Lisinopril (2.5mg), followed by Enalapril (10mg) 394.16%, Telmisartan (20mg) 322.22%.Conclusions: There is a wide difference in the cost of different brands of ACE Inhibitors and ARBs available in India. They have important role in management of hypertension particularly if associated with other morbidities like diabetes. The clinicians prescribing these drugs should be aware of these variations in cost so as to reduce the cost of drug therapy and increase the patient adherence to the therapy.

scholarly journals The Impact of CEOs' Compensations on Cost Stickiness in Industrial Companies Listed on the Amman Stock Exchange

2021 ◽  
Vol 15 (1) ◽  
pp. 152
Author(s):  
Lina Fuad Hussien
Keyword(s):  
Stock Exchange ◽  
Industrial Companies ◽  
Level Of Activity ◽  
Cost Behavior ◽  
Study Population ◽  
The Difference ◽  
High Level ◽  
The Cost ◽  
The Impact ◽  
Cost Stickiness

The purpose of this study is to analyze the asymmetry in cost behavior (cost stickiness) and to identify the impact of CEOs' compensation on the degree of cost stickiness behavior. The study population consists of the public shareholding companies listed on the ASE, which number (56) industrial company. Data were collected from (35) industrial companies for the period (2009 - 2019). To measure the degree of costs stickiness, The Model of Weiss (2010) was used. The Model of Weiss (2010) takes into account the costs and changes in the level of activity (sales) for the last four quarters of the company, Weiss (2010) model constructs the difference in logarithmic ratios of changes in cost. The study found that the CEO's compensation in Jordanian industrial companies consists of two forms. The companies pay fixed salaries or performance-related bonuses. The study found that the form of compensation that is paid to the CEO affects the behavior of managers. The results indicated that the performance-related rewards are accompanied by a decrease in the level of cost stickiness, and the compensation paid in the form of fixed salaries are accompanied by a high level of cost stickiness. The study recommends that companies should understand the role of the compensation form in administrative decisions, especially with regard to resource modifications, as management motives in relation to resource modifications must be taken into account because of their clear and direct impact on the cost structure of companies.

scholarly journals ANALISIS KETERLAMBATAN PROYEK SERTA DAMPAKNYA TERHADAP BIAYA DAN WAKTU PELAKSANAAN PROYEK

2019 ◽  
Vol 5 (1) ◽  
pp. 13-19
Author(s):  
Fitri Nur Kharina ◽  
Kusno Adi Sambowo
Keyword(s):  
Construction Projects ◽  
Construction Project ◽  
Project Performance ◽  
Project Work ◽  
Earned Value ◽  
Time Period ◽  
Review Period ◽  
The Difference ◽  
The Cost ◽  
The Impact

Construction projects in all regions continues to be developed for the creation of facilities that can be utilized by the community. One of them is the construction of apartments which are now being intensively carried out to meet residential needs for the community. Making a construction project plan always refers to estimates that exist at the time development plan is made, therefore problems can arise if there is a discrepancy between the plans that have been made and the actual reality. So the impact that often occurs is the delay in the time of project implementation which can also be accompanied by an increase in the cost of implementing the project. In the construction project of Cinere Terrace Suites Apartemen & Citywalk, Jakarta there was a delay resulting in a late payment of monthly bill progress by the owner. Based on the above reasons, this research was conducted to find out how the project performance was seen from the cost and time period of the review period. how is the estimated cost and time to complete the overall project work. The method used in the analysis of this study is the Earned Value Method. Based on the results of the analysis carried out for 29 weeks the project performance on schedule has been delayed and cost shows a positive value. For the estimated completion time of the project there is an increase in time whose duration increases from the planned 98 weeks or 685 days to 109,624 weeks or 768 days. While the estimated cost of completing the project from the results of the analysis obtained a value of Rp. 270,147,448,569.16 smaller than the planned cost of Rp. 315,272,727,272.73. With the difference VAC of Rp. 45,125,278,703.57 this shows that there are benefits obtained by the contractor.

scholarly journals The impact of China's retail drug price control policy on hospital expenditures: a case study in two Shandong hospitals

2005 ◽  
Vol 20 (3) ◽  
pp. 185-196 ◽  
Author(s):  
Qingyue Meng ◽  
Gang Cheng ◽  
Lynn Silver ◽  
Xiaojie Sun ◽  
Clas Rehnberg ◽  
...  
Keyword(s):  
Drug Price ◽  
Control Policy ◽  
Price Control ◽  
Hospital Expenditures ◽  
The Impact

scholarly journals Use of Biatain dressing material in patients with diabetic foot syndrome: randomized comparative study

2009 ◽  
Vol 12 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Oleg Viktorovich Udovichenko ◽  
Evgenia Viktorovna Bublik
Keyword(s):  
Treatment Modalities ◽  
High Tech ◽  
Safety Parameters ◽  
Retail Prices ◽  
Type Size ◽  
Insignificant Difference ◽  
Costs Of Treatment ◽  
The Difference ◽  
Group 2 ◽  
The Cost

Aim. To compare efficiency, safety, and cost of different treatment modalities. Materials and methods. The study included 40 patients with type 1 and 2 diabetes, foot and lower leg trophic ulcers at granulation stage I-II (Wagners classification)free from wound infection. The patients were randomized for the treatment during 2 months with a Biatain dressing (Coloplast, Denmark)(group1) and for conventional treatment with the use of an atraumatic mesh dressing (group 2). Biatain dressings were changed every 2-4 (up to 5) daysand conventional dressings once daily. Patients in the two groups were adjusted for age, sex, ulcer type, size and duration, length of antibiotic therapy beforeand during treatment, blood glucose level, and other characteristics (p>0.05). Results. Ulcers healed within 2 months in 70% of the patients in group 1 and in 53.3% in group 2 (insignificant difference, p = 0.48). Other efficiency (medianhealing time, survival curves) and safety parameters were not significantly different either. The cost of treatment by the two methods was comparabledespite a higher cost of Biatain dressings due to their rarer change and economy of material for secondary dressing. When dressings were changed by medicalprofessionals rather than by the patient or his (her) relatives at home, treatment with the use of Biatain dressings proved 1.75 times cheaper. Conclusion. Efficiency and safety of high-tech and conventional dressing materials is comparable. The real difference between the costs of treatment byeither method is significantly smaller than the difference between retail prices of the two materials. Cost effectiveness of high-tech dressings is higher if thetreatment is accomplished in a medical facility.

Cost-effectiveness of two screening strategies for Chlamydia trachomatis and Neisseria gonorrhoeae as part of the PrEP programme in the Netherlands: a modelling study

2021 ◽  
pp. sextrans-2020-054741
Author(s):  
Francine van Wifferen ◽  
Elske Hoornenborg ◽  
Maarten F Schim van der Loeff ◽  
Janneke Heijne ◽  
Albert Jan van Hoek
Keyword(s):  
At Risk ◽  
Cost Effectiveness ◽  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Infection Model ◽  
Baseline Scenario ◽  
Life Years ◽  
The Difference ◽  
The Cost ◽  
The Impact

ObjectivesPre-exposure prophylaxis (PrEP) users are routinely tested four times a year (3 monthly) for asymptomatic Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections on three anatomical locations. Given the high costs of this testing to the PrEP programme, we assessed the impact of 3 monthly screening(current practice), compared with 6 monthly on the disease burden. We quantified the difference in impact of these two testing frequencies on the prevalence of CT and NG among all men who have sex with men (MSM) who are at risk of an STI, and explored the cost-effectiveness of 3-monthly screening compared with a baseline scenario of 6-monthly screening.MethodsA dynamic infection model was developed to simulate the transmission of CT and NG among sexually active MSM (6500 MSM on PrEP and 29 531 MSM not on PrEP), and the impact of two different test frequencies over a 10-year period. The difference in number of averted infections was used to calculate incremental costs and quality-adjusted life-years (QALY) as well as an incremental cost-effectiveness ratio (ICER) from a societal perspective.ResultsCompared with 6-monthly screening, 3-monthly screening of PrEP users for CT and NG cost an additional €46.8 million over a period of 10 years. Both screening frequencies would significantly reduce the prevalence of CT and NG, but 3-monthly screening would avert and extra ~18 250 CT and NG infections compared with 6-monthly screening, resulting in a gain of ~81 QALYs. The corresponding ICER was ~€430 000 per QALY gained, which exceeded the cost-effectiveness threshold of €20 000 per QALY.ConclusionsThree-monthly screening for CT and NG among MSM on PrEP is not cost-effective compared with 6-monthly screening. The ICER becomes more favourable when a smaller fraction of all MSM at risk for an STI are screened. Reducing the screening frequency could be considered when the PrEP programme is established and the prevalence of CT and NG decline.

Competitive Dynamics in Hierarchically Organized Markets: Spatial Duopoly and Demand Asymmetries

1996 ◽  
Vol 28 (11) ◽  
pp. 2021-2040 ◽  
Author(s):  
P Plummer
Keyword(s):  
Pricing Strategies ◽  
Market Demand ◽  
Price Equilibrium ◽  
Urban Market ◽  
Existence And Stability ◽  
Retail Prices ◽  
Spatial Duopoly ◽  
Spatial Price ◽  
The Cost ◽  
The Impact

In recent years, there has been considerable interest in the impact of corporate organizational structure on the configuration of prices, outputs, and profits in spatially extensive markets. In previous research I examined the general and analytical conditions defining both the existence and stability of an equilibrium in hierarchically organized spatial markets dominated by oligopolistic corporations that distribute a commodity directly to consumers through their retail franchises. Here I examine the disequilibrium dynamics resulting from this model. A bilevel decisionmaking process is hypothesized in which corporations vary their delivered prices in response to changes in urban market demand and in which franchises vary their retail prices in response both to changes in the cost of the commodity from their parent corporation and to the pricing strategies pursued by their competitors. The complexity of interactions operating between the two levels of the model and the presence of asymmetrical demand conditions facing duopolistic corporations suggests that it is unlikely that an overall spatial price equilibrium can actually be reached by such disequilibrium price-adjustment strategies.

scholarly journals Does price regulation affect atorvastatin sales in India? An impact assessment through interrupted time series analysis

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e024200
Author(s):  
Sakthivel Selvaraj ◽  
Habib Hasan Farooqui ◽  
Aashna Mehta
Keyword(s):  
Time Series ◽  
Time Series Analysis ◽  
Market Share ◽  
Drug Price ◽  
Interrupted Time Series ◽  
Price Control ◽  
Price Regulation ◽  
Interrupted Time Series Analysis ◽  
Series Analysis ◽  
The Impact

ObjectiveThe objective of this study was to examine the impact of medicines price regulation (Drug Price Control Order, 2013) on the market share of atorvastatin in the Indian retail market for statins.SettingAll Indian states, January 2012 to December 2015.DesignQuasi-experimental—interrupted time series analysis.DataPharmaceutical sales audit data set from IMS Health (now IQVIA) for the 48-month period from January 2012 to December 2015.Outcome measureShare of atorvastatin (in percentage) in the Indian market for statins in terms of sales volumes.ResultsWe observed that the price regulation notification (Drug Price Control Orders, 2013) was associated with 0.12% (p<0.001; 95% CI 0.06 to 0.18) increase in the trend of the average monthly market share of atorvastatin (5 mg and 10 mg). After 31 months of price ceilings notification, the average market share of atorvastatin was 3.41% higher than would have been expected had the price ceilings not been notified. In sensitivity analysis, with a control, our findings remain robust, we observed a 0.16% (p<0.001; 95% CI 0.08 to 0.24) rise in the trend of average monthly market share of atorvastatin (5 mg and 10 mg) as compared with the change in the control.ConclusionsPrice control as a public intervention did improve the relative sales of atorvastatin in the statin market in India.

scholarly journals The impact of the oil palm plantation area on the community economy in East Kutai Regency, East

2020 ◽  
Vol 9 (4) ◽  
pp. 130-137
Author(s):  
Zulkarnain Zulkarnain
Keyword(s):  
Data Analysis ◽  
Sampling Method ◽  
Community Economy ◽  
Plantation Development ◽  
Regional Influence ◽  
The Difference ◽  
Using Data ◽  
The Cost ◽  
The Impact ◽  
Data Analysis Methods

This article is about how the impact of change and the extent of existing activities contribute to the surrounding community. The development of large private plantations in the East Kutai Regency has also been inseparable from problems, especially in the management of plasma plantations carried out by large plantation companies. Issues that arise include the difference in productivity between nucleus and plasma plantations, the low acceptance of plasma farmers so that it is considered not to improve the welfare of the community. The purpose of this study was to determine the impact of large private plantations on community welfare, evaluating the implementation of plantation development activities in the East Kutai Regency. The sampling method is done by purposed sampling using data analysis methods, the analysis of the cost of the benefits of the area, the analysis of the level of welfare, and analysis of regional influence. With the results of the study as follows: the cost of benefits is positive; the multiplier value is 2,614 and the value of NTM is 0.37.

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