scholarly journals Incidence of retinal changes in pregnant women due to pregnancy induced hypertension and its correlation with clinical profile

2020 ◽  
Vol 9 (4) ◽  
pp. 1640
Author(s):  
Himanshy Rai ◽  
Zakia Rahman
Keyword(s):  
Sudden Onset ◽  
Response To Treatment ◽  
Positive Finding ◽  
Pregnancy Induced Hypertension ◽  
Medical College ◽  
Induced Hypertension ◽  
Grade Ii ◽  
Mild Preeclampsia ◽  
Severity Of The Disease ◽  
Routine Therapy

Background: Pregnancy induced hypertension (PIH) is associated with many other pathological complications. Pathological changes of this disease appear to be related to vascular endothelial dysfunction and its consequences. One such complication or effect of PIH is retinal changes.Methods: This observational study was conducted of 110 cases over a period of 12 months from March 2018 to February 2019 in department of obstetrics of gynecology in Kamla Raja Hospital, G. R. Medical College, Gwalior, Madhya Pradesh. All the patients who fulfilled the diagnostic criteria of PIH admitted in the obstetric ward.Results: Retinopathic changes were noted in 36.36% out of which grade I, grade II, grade III and grade IV have 11.82%, 8.18%, 10.19% and 5.45% cases respectively. In + proteinuria 10.9% of cases have positive findings, in ++ proteinuria 18.18% cases have positive findings, in +++ 7.27% cases have retinopathy but severity increases with a grade of proteinuria. 40% cases retinopathic changes of mild preeclampsia have positive finding, 36.36% in severe preeclampsia and 23.64% in cases of eclampsia. As overall severity of PIH increases retinopathies in patients increases.Conclusions: Visual symptoms are few in patients with PIH and often absent unless the macula is involved. Sudden onset of headache, which is resistant to routine therapy in these patients, may be the warning symptom before the onset of first convulsion. By repeated fundus examinations at regular intervals one can assess the severity of the disease and also response to treatment instituted.

scholarly journals LDH as a prognostic marker in hypertensive pregnancy

2017 ◽  
Vol 6 (6) ◽  
pp. 2444
Author(s):  
Prathap Talwar ◽  
Triveni Kondareddy ◽  
Pranidha Shree C. A.
Keyword(s):  
Lactic Dehydrogenase ◽  
High Serum ◽  
Pregnancy Induced Hypertension ◽  
Intracellular Enzyme ◽  
Cellular Death ◽  
Severity Of Disease ◽  
Induced Hypertension ◽  
Prospective Comparative Study ◽  
Severity Of The Disease ◽  
Poor Outcomes

Background: Pregnancy induced hypertension (PIH) is a global problem with a 5-15% incidence rate in India and complicating 10-17% of all pregnancies. These are multisystem disorders and lead to a lot of cellular death. LDH is an intracellular enzyme and its level is increased in these women due to cellular death. So, serum LDH levels can be used to assess the extent of cellular death and thereby the severity of disease in this group of women. The objective of the study was to correlate the severity of the disease, maternal and perinatal outcome with Lactic Dehydrogenase (LDH) levels in serum in patients of preeclampsia and eclampsia.Methods: A prospective comparative study was conducted in the department of Obstetrics and Gynecology, JSS Medical Hospital, Mysore.Results: LDH levels were significantly elevated in women with preeclampsia and eclampsia (<0.001). Higher LDH levels had significant correlation with high blood pressure (P <0.10) as well as poor maternal and perinatal outcome.Conclusions: High serum LDH levels correlate well with the severity of the disease and poor outcomes in patients of preeclampsia and eclampsia.

scholarly journals Hematological changes in pregnancy induced hypertension in their third trimester at Jhalawar Medical College, Jhalawar, India

2019 ◽  
Vol 8 (9) ◽  
pp. 3497
Author(s):  
Neelam Jhajharia ◽  
Madhureema Verma
Keyword(s):  
Control Group ◽  
Case Group ◽  
Haematocrit Level ◽  
Haematological Parameter ◽  
Pregnancy Induced Hypertension ◽  
Medical College ◽  
Induced Hypertension ◽  
Life Threatening ◽  
The Mean ◽  
And Control

Background: Pregnancy induced hypertension (PIH) is one of the most common and potential life-threatening complications of pregnancy. This study is aimed to investigate and correlate the hemoglobin, haematocrit, white blood cell count, lymphocytes and platelets in PIH patients in their third trimester.Method: Total 126 subjects were studied out of them 63 patients (case) and 63 healthy pregnant women (control) visiting the Obstetrics and Gynaecology department Jhalawar Medical College, Jhalawar were registered in the study and followed during their pregnancy. Two millilitre of blood sample was drawn aseptically using the 5ml syringe from the median ante cubital vein of all the cases and control participants into EDTA-anticoagulated tubes. Haematological parameter calculated by using Sysmex XN-9100™ Automated Haematology System.Results: The mean hemoglobin level of the case group (8.8206±2.53779) was significantly lower than that of the control group (9.7289±2.47033) (p<0.05). The mean platelet count of the case group (131.4937±62.05999) was significantly lower than that of the control group (324.9683±230.78764) (p<0.05). The mean lymphocytes level of case group (1.2510±0.56369) was significantly lower than that of the control group (1.9295±1.4150) (p<0.05). The mean WBC level of case group (36.3467±119.90635) was significantly high than control group (11.5260±4.83059) (p<0.05). The mean haematocrit level of case group (32.6851±7.29789) was significantly high than control group (30.0424±23.38116) (p<0.05).Conclusion: The mean hemoglobin, mean platelets and mean lymphocytes are lower in PIH patients. The mean WBC and haematocrit are higher in PIH patient. 

scholarly journals PREVALENCE OF FUNDUS CHANGES IN PREGNANCY INDUCED HYPERTENSION – A CLINICAL STUDY

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Manpreet Kour ◽  
Vijayta Gupta
Keyword(s):  
Clinical Study ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Changes In Pregnancy ◽  
Severity Of The Disease ◽  
In Pregnancy

To evaluate prevalence of fundus changes in Pregnancy Induced Hypertension (PIH) and to find the correlation of the findings with the levels of hypertension and with the severity of the disease.

scholarly journals PREGNANCY INDUCED HYPERTENSION;

2014 ◽  
Vol 21 (03) ◽  
Author(s):  
Asghar Khan ◽  
Amin Fahim ◽  
Aneela Qureshi ◽  
Ghulam Shah Nizamani ◽  
Mohammad Ahmed Azmi
Keyword(s):  
University Hospital ◽  
Control Group ◽  
P Value ◽  
Pregnancy Induced Hypertension ◽  
Severity Of Disease ◽  
Induced Hypertension ◽  
Mild Preeclampsia ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Objective: To assess the early detection of thrombocytopenia in womenpresenting with varying degree of pregnancy induced hypertension (PIH). Study Design: A casecontrol study. Place of Study: Hematology laboratory Isra University Hospital Hyderabad.Duration of Study: From July 2009 to December 2010. Materials and Methods: Total 130pregnant women were included in this study. The subjects were divided into three groups asGroup 1 with pre-eclampsia, Group 2 with eclampsia and Group 3 with normotensive pregnantwomen as control group. The Group 1 was further divided into two sub groups such as Subgroup1a with mild preeclampsia and Sub-group 2b with severe pre-eclampsia. Results:Anticoagulated whole blood samples (5cc) from all subjects were analyzed for the detection ofthrombocytopenia for the possible involvement of pregnancy induced hypertension. It was notedthat out of total subjects, 33(25.39%) had mild pre-eclampsia, 17(13.07%) had severe preeclampsia,15(11.54%) had eclampsia and 65 (50.0%) were normotensive pregnant women.Based on the comparative findings, the results showed significant differences between group 3and group 1a (p-value 0.001), group 3 and group 1b (p-value 0.001), group 2 and group 3 alsoshowed same results (p-value 0.001) but the subjects of group 1a and 1b when compared,showed non-significant findings (p value 0.955). Conclusion: The results suggested that earlydetection of platelet count provide significant role for the assessment of severity of disease inwomen with pregnancy induced hypertension when compared with normotensive pregnantwomen.

scholarly journals Neonatal Outcome of Antenatal Mothers with Pregnancy Induced Hypertension in Antenatal Ward of Kathmandu Medical College and Teaching Hospital

2018 ◽  
Vol 2 (3) ◽  
pp. 255-259
Author(s):  
Santoshi Shrestha Pradhan ◽  
Sabitra Paudel ◽  
Puspa Parajuli ◽  
Bina Rana Khagi
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Apgar Score ◽  
Neonatal Death ◽  
Neonatal Outcome ◽  
Pregnancy Induced Hypertension ◽  
Perinatal Morbidity ◽  
Medical College ◽  
Induced Hypertension ◽  
Perinatal Management

Introduction: Hypertensive disorders seem to complicated in approximately 5-15% of pregnancies. Pregnancy induced hypertension (PIH) increases the risk of maternal and perinatal morbidity and mortality.Objective: To assess the neonatal outcome and to identify the association between the demographic variables and outcome of Pregnancy Induced Hypertension in antenatal ward of Kathmandu Medical College and Teaching Hospital.Methodology: Prospective study design was conducted for the study in Obstetrics ward of Kathmandu Medical College Teaching Hospital. The population was the 100 antenatal mothers with pregnancy induced hypertension admitted in antenatal ward and purposive convenient sampling technique was used to collect the data. The structured questionnaire was designed and the data was collected through interview technique from 1st February 2014 to 10 March 2016. The collected data was analyzed using SPSS programme.Results: Regarding neonatal outcome the findings of the study showed that most of the babies 83% had normal weight. The most of the babies 82% had adequate for gestational age. Regarding Apgar score half of the babies 50% scored mild asphyxia at the first minute whereas most of the babies 93% scored no asphyxia at five minutes after delivery. Regarding perinatal outcome 13% babies were delivered premature, 7% had birth asphyxia, 5% were born with low birth weight and stillbirth whereas only 1% had early neonatal death. The present study revealed that there was significant association between gestational age of delivery and Apgar score at 5 minutes and there was significant association between age and perinatal management outcome, gestational age of delivery and perinatal morbidity management, grading of proteinuria and perinatal morbidity management, grading of oedema and perinatal management outcome regarding neonatal outcome of pregnancy induced hypertension.Conclusion: Pregnancy induced hypertension during pregnancy were associated with a higher risk of adverse neonatal outcomes. Women with pregnancy induced hypertension during pregnancy had a higher risk of emergency caesarean section, pre-term birth, neonatal death, low birth weight children and neonates with low Apgar score. Maternal and fetal morbidity and mortality can be reduced by early recognition and institutional management.Birat Journal of Health SciencesVol.2/No.3/Issue 4/Sep- Dec 2017, Page: 255-259

Role of Labetalol in Control of Hypertension during Pregnancy

2021 ◽  
Vol 15 (5) ◽  
pp. 1061-1063
Author(s):  
Farzana Ramzan ◽  
Sara Qadir ◽  
Sardar Gul Zarin ◽  
Fatima Tahir ◽  
Sajid Malik
Keyword(s):  
Blood Pressure ◽  
Effective Dose ◽  
Case Series ◽  
Pregnancy Induced Hypertension ◽  
Effective Agent ◽  
Medical College ◽  
Induced Hypertension ◽  
Keywords Pregnancy ◽  
Age Range

Aim: To valuate the effectiveness of labetalol in controlling hypertension during pregnancy. Study design: Descriptive case series Place and duration of study: Department of Obstetrics & Gynaecology, Allama Iqbal Medical College/Jinnah Hospital Lahore from 1st September 2018 to 31st March 2019. Methodology: Sixty four patients were enrolled. All the patients were started with lowest effective dose of100mg orally three times daily and if required after 72 hours, the escalation dose up to 200mg every 8hours. When adequate reduction in blood pressure was obtained it was labelled as achievement of primary end point. Results: The age range between 18-35 years with mean age 25.8±5.0 years. There were 12 primigravida (18.8%) and multigravida 52(81.2%). Reduction in blood pressure was observed in56 cases (87.5%). Conclusion: The labetalol appears to be an effective agent in controlling hypertension during pregnancy with possible advantages and no apparent disadvantage during its use. Keywords: Pregnancy-induced hypertension; Labetalol, Control of hypertension

scholarly journals Maternal And Fetal Outcome Following Severe Anaemia In Pregnancy: Results From Nobel Medical College Teaching Hospital, Biratnagar, Nepal.

2013 ◽  
Vol 2 (1) ◽  
pp. 22-26
Author(s):  
Ram Hari Ghimire ◽  
Sita Ghimire
Keyword(s):  
Birth Weight ◽  
Postpartum Haemorrhage ◽  
Fetal Death ◽  
Severe Anaemia ◽  
Exposed Group ◽  
Intrauterine Fetal Death ◽  
Pregnancy Induced Hypertension ◽  
Medical College ◽  
Induced Hypertension ◽  
In Pregnancy

Background: anaemia is a major contributor to maternal death in developing countries. Since it reduces resistance to blood loss, death may occur from bleeding associated with normal delivery. Objective: To explore the association between anaemia and maternal and perinatal complications. Study Design: Retrospective cohort study. Materials and Methods: 100 pregnant women admitted for delivery and having severe anaemia were studied and compared with 100 non anaemic women matched for age, parity, and gestational age. Adverse outcomes analysed were: pregnancy induced hypertension, Postpartum haemorrhage hypertension, Abruptio Placenta,, Infection, Maternal Mortality, Low Birth Weight, and Perinatal mortality. Results : Compared to nonexposed women, exposed women had an increased risk of pregnancy induced hypertension with odds ratio of 5.06 . Postpartum haemorrhage, incidence of wound infection,Intermediate care unit admission were statistically significant in exposed group .However there was no significant difference in maternal mortality among study group.APGAR score <7 in 5 minutes was 18%in exposed group and 5% in non exposed group (p=0.0039). Intrauterine fetal death was 6% in cases and none of respondants from control group had Intrauterine fetal death (p=0.0128). Frequency of low birth weight was 22% in exposed group and 9% in non exposed group(p=0.011). Conclusions: The burden of anemia in pregnant population is still high in eastern region of Nepal. Severe anemia in pregnancy carries significant risk to mother and fetus. Hence preventive measures need to be implemented at community level. Public awareness regarding pre-pregnancy hemoglobin status and importance of antenatal checkup relating with maternal and fetal adverse pregnancy outcome should be initiated. Journal of Nobel Medical College Vol. 2, No.1 Issue 3 Nov.-April 2013 Page 22-26 DOI: http://dx.doi.org/10.3126/jonmc.v2i1.7668

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