scholarly journals A case report of primary ovarian leiomyoma

2020 ◽  
Vol 9 (10) ◽  
pp. 4313
Author(s):  
Srikala Doddareddy ◽  
Nagashree Undinti ◽  
Vishnu Vandana G.
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Blood Vessels ◽  
Surgical Management ◽  
Final Diagnosis ◽  
Ovarian Tumors ◽  
Unmarried Woman ◽  
Lower Abdomen ◽  
Mesenchymal Tumour

Primary ovarian Leimyoma is a rare benign mesenchymal tumour usually arising from smooth muscle of walls of ovarian blood vessels. It’s mostly discovered incidentally. Here we report a case in which a 24-year-old unmarried woman presented with pain and discomfort in lower abdomen since 10 days. On further evaluation through imaging and blood works, we proceeded with surgical management. Immunohistochemistry confirmed the final diagnosis of ovarian leiomyoma. However, it’s important to keep this entity as a differential diagnosis for solid ovarian tumors.

scholarly journals Uterine Angiomyolipoma: A Case Report, Differential Diagnosis with Pecoma and Review of the Literature

2014 ◽  
Vol 7 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Tihomir P. Totev ◽  
Svetlana A. Mateva ◽  
Margarita R. Nikolova ◽  
Grigor A. Gorchev
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Smooth Muscle ◽  
Case Report ◽  
Final Diagnosis ◽  
Morphological Aspect ◽  
Review Of The Literature ◽  
Immunohistochemical Examination ◽  
Mesenchymal Neoplasms ◽  
Vascular Component

Abstract Angiomyolipomas are benign mesenchymal neoplasms, presenting with a variable mixture of adipose tissue, smooth muscle and vascular component. Although they are typically found in the kidneys, many cases of extrarenal angiomyolipomas have been reported. They are extremely rarely present in the uterus. We describe a case of a 56-year-old woman, operated on for leiomyoma. Total laparohysterectomy and bilateral adnexectomy was performed. After histological and immunohistochemical examination, the final diagnosis of uterine angiomyolipoma was made. Renal and extrarenal angiomyolipomas are compared in regard to clinical and morphological aspect and their difference from PEComas is dicussed. PEComas have been defined during the last decade and there are still issues regarding terminological clarity and overlapping.

scholarly journals Large intraperitoneal lipoleiomyoma in a pre-menopausal woman: a case report

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sara L. Schaefer ◽  
Amy L. Strong ◽  
Sheena Bahroloomi ◽  
Jichang Han ◽  
Michella K. Whisman ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Actin ◽  
Abdominal Mass ◽  
Histopathological Analysis ◽  
Menopausal Woman ◽  
En Bloc ◽  
Cross Sectional

Abstract Background Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations. Case presentation We describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved. Conclusions Lipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.

Rapid growth of myxoid leiomyosarcoma of the vulva during pregnancy: a case report

2004 ◽  
Vol 14 (1) ◽  
pp. 172-175 ◽  
Author(s):  
A. R. Di Gilio ◽  
G. Cormio ◽  
L. Resta ◽  
C. Carriero ◽  
V. Loizzi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Lymph Node ◽  
Cesarean Section ◽  
Recurrent Disease ◽  
Node Dissection ◽  
Smooth Muscle Tumors ◽  
Vulvar Mass

Smooth muscle tumors arising in the vulva are rare. Leiomyosarcoma is the most common variant of vulvar sarcoma, and very few cases have been reported during pregnancy. A 36-year-old woman presented with a progressively enlarging vulvar mass during pregnancy, diagnosed as a Bartholin's gland cyst. The lesion was resected at 38 weeks of gestation during cesarean section and diagnosis of myxoid leiomyosarcoma of the vulva was made. Six weeks later the patients were referred to our center and submitted to wide vulvar excision with groin lymph node dissection that revealed the presence of a small residual focus of leiomyosarcoma. At 30 months of follow-up the patient was well without any sign of recurrent disease. Leiomyosarcoma should be included in the differential diagnosis of vulvar masses; progressively enlarging vulvar lesion should be biopsied even during pregnancy. Leiomyosarcoma should be considered in the differential diagnosis of vulvar mass.

scholarly journals Somatically derived Yolk Sac tumor of the urinary bladder: A case report and differential diagnosis

2020 ◽  
Author(s):  
Nadia Espejo-Herrera ◽  
Enric Condom Mundó
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Final Diagnosis ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
High Grade ◽  
Yolk Sac Tumors ◽  
Urinary Bladder Tumor

Abstract Background: Yolk sac tumor is a germ cell neoplasm that arises predominantly in the gonads, but can also derive from somatic neoplasms in extragonadal locations. These cases have been denominated recently as “somatically derived Yolk sac tumors”, and have been documented in several locations, although reports from the urinary tract are scarce. To our knowledge, this is the first report of a Yolk sac tumor derived from urothelial carcinoma. Case presentation: We present a unique case of a 76-year-old man with a recurrent urinary bladder tumor, initially interpreted as a high grade urothelial carcinoma with glandular differentiation. In the recurrent tumor, diverse histological patterns were identified, including glandular, hepatoid and sarcomatoid. This tumor showed positivity for AFP, GLP3 and SALL4, and negativity for CK7 and EMA. Fluorescent in situ hybridization study showed a polysomic pattern of chromosome 12. All these findings led to the final diagnosis of a Yolk sac tumor derived from urothelial carcinoma. Conclusions: Somatically derived Yolk Sac tumors should be considered in the differential diagnosis of a high grade urothelial carcinoma, particularly when glandular and other unusual patterns are observed. Key words: Yolk sac tumor, somatically derived, urothelial carcinoma, urinary bladder, case report.

scholarly journals Angioleiomyoma of the Larynx: A Case Report and Literature Review

2020 ◽  
Vol 99 (10) ◽  
pp. 658-663
Author(s):  
Federica Perardi ◽  
Giuseppe Abbate ◽  
Leonardo R. Iannuzzelli ◽  
Rossella Contini ◽  
Manuela De Munari ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Gold Standard ◽  
Carbon Dioxide Laser ◽  
Standard Treatment ◽  
Surgical Excision ◽  
Laser Technology ◽  
Complete Surgical Excision

Angioleiomyoma is a benign smooth muscle and vessel tumor; laryngeal localization is extremely rare with only 24 cases described in the literature; moreover, it should be considered in the differential diagnosis of laryngeal mass. Endoscopic complete surgical excision with dissection along capsule is now considered the gold-standard treatment for small and well-circumscribed laryngeal angioleiomyoma. We present a case of laryngeal angioleiomyoma successfully treated with carbon dioxide laser technology which resulted in a bleeding reduction and adequate hemostasis with less tissue damage and good functional outcome.

Struma Ovarii : A Rare Monodermal Teratoma

JMS SKIMS ◽  
2017 ◽  
Vol 20 (1) ◽  
pp. 41-43
Author(s):  
Abdul Rasheed Rather ◽  
Shazia Bashir ◽  
Ather Hafiz Khan ◽  
Ashfaq Ul Hassan ◽  
Mohsin Ul Rasool ◽  
...  
Keyword(s):  
Ct Scan ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Ovarian Tumors ◽  
Rare Tumor ◽  
Struma Ovarii ◽  
Lower Abdomen ◽  
Loss Of Appetite ◽  
Adnexal Lesion

Struma ovarii is a rare tumor of ovary which accounts for 1% of all ovarian tumors and 3% 0f all dermoid tumors. It belongs to the group of monodermal teratomas. We present a case of struma ovarii in a 55 year old women who presented with symptoms of pain in lower abdomen and loss of appetite for the last one month. Radiological investigations including USG, CT scan and MRI revealed a complex right adnexal lesion. Final diagnosis of struma ovarii was made on histopathological examination which revealed colloid filled thyroid follicles lined by cuboidal epithelium. JMS 2017; 20(1):41-43

scholarly journals Bilateral giant angiomyolipomas revealed after massive retroperitoneal hemorrhage: A case report

2014 ◽  
Vol 71 (4) ◽  
pp. 408-412 ◽  
Author(s):  
Sladjana Petrovic ◽  
Aleksandar Tasic ◽  
Dragan Mihailovic ◽  
Nikola Zivkovic ◽  
Marija Vitanovic ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Blood Vessels ◽  
Left Kidney ◽  
Vena Cava ◽  
Massive Hemorrhage ◽  
Epithelioid Angiomyolipoma ◽  
Retroperitoneal Hemorrhage ◽  
True Nature ◽  
The Right

Introduction. Angiomyolipomas (AML) are benign neoplasms composed of fat, smooth muscle and thick-walled blood vessels in varying proportions. These tumors have a significant female predominance. Case report. We reported a 61-year-old man with spontaneous rupture of AML. Computerized tomography revealed a change in morphology of both kidneys. Multiple lesions of fat density with dilated blood vessels were found in the left kidney. The right retroperitoneum was obliterated with a giant heterogeneous mass originating from the right kidney with a massive hemorrhage, active extravasations, compression of inferior the vena cava and intraperitoneal collections. After radical nephrectomy, histological examination revealed that the tumor was composed of relative proportions of fat, smooth muscle and blood vessels. We incidentally found small renal adenoma. Conclusion. The true nature of AML is unclear, but they are usually classified as hamartomas. Angiomyolipomas are generally benign lesions, although the epithelioid angiomyolipoma, a subtype that occurs in about 3% of cases, can behavior aggressively.

scholarly journals Review of the pathophysiology, diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor

2017 ◽  
Vol 46 (2) ◽  
pp. 663-674 ◽  
Author(s):  
Chao Sun ◽  
Junkai Zou ◽  
Qing Wang ◽  
Qi Wang ◽  
Lu Han ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
English Language ◽  
External Genitalia ◽  
Surgical Excision ◽  
Smooth Muscle Tumor ◽  
Final Diagnosis ◽  
Diagnosis And Therapy ◽  
Long Term Follow Up ◽  
Muscle Tumor

The objective of this article is to discuss the pathophysiology, diagnosis, differential diagnosis, and therapy of vulvar leiomyoma. We performed a review of all English-language reports of vulvar leiomyoma published in PubMed from 1978 to 2015 using the following search terms: “vulval leiomyoma,” “vulvar leiomyoma,” “vulval smooth muscle tumor,” and “external genitalia smooth muscle tumor.” Vulvar leiomyomas, which are rare benign monoclonal tumors, most commonly occur in the fourth and fifth decades of life. The genetics of vulvar leiomyoma remain undefined. Three principal histological patterns have been identified: spindled, epithelioid, and myxoid. Imaging tests such as ultrasound, endoscopic ultrasound, and magnetic resonance imaging are used in diagnosis. Surgical excision is the only curative treatment for vulvar leiomyomas. Establishment of a full differential diagnosis list and correct final diagnosis before surgery are essential for optimal clinical management. Although recurrence of vulvar leiomyoma is extremely rare, long-term follow-up of all cases is advisable.

scholarly journals Progression of Hepatic Adenoma to Carcinoma in the Setting of Hepatoportal Sclerosis in HIV Patient: Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
M. I. Montenovo ◽  
F. G. Jalikis ◽  
M. Yeh ◽  
J. D. Reyes
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Liver Disease ◽  
Clinical Presentation ◽  
Final Diagnosis ◽  
Hepatic Adenoma ◽  
Review Of The Literature ◽  
Patient Case ◽  
Hepatoportal Sclerosis ◽  
First Case

We report a case of hepatic adenoma progression to carcinoma in the setting of hepatoportal sclerosis in an HIV+ patient and provide a review of the scarce literature regarding hepatoportal sclerosis in HIV patients. We describe the clinical presentation, diagnostic workup, and management. This is the first case report in the literature of progression of hepatic adenoma to carcinoma in hepatoportal sclerosis in an HIV patient. This case also highlights the broad differential diagnosis that should always be included in the study of any liver disease in this patient population, including the performance of invasive and aggressive tests to arrive at the final diagnosis.

Angioleiomyoma of the Lower Leg

2017 ◽  
Vol 107 (3) ◽  
pp. 244-247 ◽  
Author(s):  
Robert L.B. Sprinkle ◽  
Omar P. Sangueza ◽  
Ashleigh E. Wells
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Lower Extremity ◽  
Excisional Biopsy ◽  
Lower Leg ◽  
Clinical Findings ◽  
Common Site ◽  
Subcutaneous Tissues ◽  
Vascular Structures

Angioleiomyomas are benign tumefactions that originate from smooth muscle in vascular structures and are difficult to definitively diagnose preoperatively. Although these lesions are rarely encountered in the foot, the lower extremity is the most common site of occurrence. An angioleiomyoma typically manifests as a small, painful, solitary, mobile lesion. This case report describes a lateral retromalleolar para–Achilles tendon insertional location for a moderately sized immobile solid tumefaction in the subcutaneous tissues. The lesion was nonpainful and progressively enlarged over 5 years. An excisional biopsy was performed, and the nodular lesion was subsequently diagnosed histopathologically as an angioleiomyoma. Owing to the ambiguous nature of the clinical findings, angioleiomyoma should be included in the differential diagnosis of lower-extremity soft-tissue manifestations.

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