scholarly journals Case series on mullerian anomalies incidence during caesarean section over one year period

2021 ◽  
Vol 11 (1) ◽  
pp. 243
Author(s):  
Mukta Jain ◽  
Komal Vijaywargiya ◽  
Aayushi Ruia
Keyword(s):  
Cesarean Section ◽  
Perinatal Outcome ◽  
Case Series ◽  
Late Pregnancy ◽  
Time Period ◽  
Uterine Anomalies ◽  
Embryonic Life ◽  
Recurrent Pregnancy Losses ◽  
Obstetrical Outcome ◽  
One Year

Congenital uterine anomalies occur due to abnormal fusion of Mullerian duct during embryonic life. It is associated with high incidences of reproductive failures and adverse obstetrical outcomes. It may be associated with malpresentation, preterm labour or recurrent pregnancy losses. The association of congenital anomalies and early pregnancy loss has been well established but its adverse effect on late pregnancy in form of malpresentation, preterm deliveries has not yet been elaborated. Hence, this case series aimed to summarize the incidence and perinatal outcome of pregnancy in women with congenital uterine anomalies undergoing cesarean section. This was a case series which was conducted on women who underwent cesarean section at P. C. Sethi hospital, Indore between time period of October 2020 to September 2021. Out of total 1835 cesarean undergoing patients, 12 patients were found to have uterine anomalies. Out of 12 patients, 9 (75%) patients were associated with malpresentation, 4 (33.3%) patients had preterm delivery and 6 (50%) patients had low birth weight babies. Hence it can be said that women with congenital uterine anomalies were at higher incidence of malpresentation and preterm deliveries. Presence of congenital uterine anomalies were associated with adverse obstetrical outcome. This knowledge warrants the need for a larger case control study to extrapolate these findings to the general population and also to recommend the need for universal prenatal screening for uterine anomalies to improve the obstetrical and perinatal outcome in patients with uterine anomalies.

scholarly journals Case series on obstetrical outcomes in patient with uterine malformations

2020 ◽  
Vol 9 (9) ◽  
pp. 3862
Author(s):  
Kirti Solanki ◽  
Swati Kochar ◽  
Laxmi Poonia
Keyword(s):  
Preterm Labour ◽  
Case Series ◽  
Postnatal Period ◽  
Medical College ◽  
Obstetrical Outcomes ◽  
Time Period ◽  
Uterine Anomalies ◽  
Embryonic Life ◽  
Recurrent Pregnancy Losses ◽  
Uterine Malformations

Congenital uterine anomalies occur due to abnormal fusion of mullerian duct during embryonic life. It is associated with high incidences of reproductive failures and adverse obstetrical outcomes. It may be associated with malpresentation, preterm labour, or recurrent pregnancy losses. Authors report a case series of 7 patients which were admitted in obstetrics and gynaecology department of SP medical college and associated group of hospitals between time period of March 2019 to July 2019. Among 7 cases 6 cases were associated with malpresentation, 1 with abortion, and 1 with preterm labour. This series shows that uterine anomalies are associated with different obstetrical outcomes varying from totally uneventful antenatal and postnatal period to abortion or preterm labour. Prenatal diagnosis of uterine anomaly may help in improving the obstetrical outcome in these patients. 

scholarly journals Obstetrical outcome in women with congenital uterine anomalies

2017 ◽  
Vol 6 (9) ◽  
pp. 3969
Author(s):  
Poonguzhali Liston ◽  
Gomathy E.
Keyword(s):  
Adverse Effect ◽  
Pregnancy Loss ◽  
Prenatal Screening ◽  
Case Control Study ◽  
Late Pregnancy ◽  
Obstetric Outcomes ◽  
Early Pregnancy Loss ◽  
Uterine Anomalies ◽  
Obstetrical Outcome ◽  
Control Study

Background: Congenital uterine anomalies are associated with higher incidence of reproductive failure and adverse obstetrical outcomes. The association of congenital anomalies and early pregnancy loss has been well established but its adverse effect on late pregnancy in from of malpresentation, preterm deliveries has not yet been elaborated. Thus, this study aims to summarize the clinical characteristics and perinatal outcome of pregnancy in women with congenital uterine anomalies.Methods: This is a retrospective study evaluating the obstetric outcomes of 32 patients with congenital abnormalities.Results: Among 32 women with uterine anomalies 6 delivered preterm, 16 malpresentations were seen (50%).Infants born to mothers having congenital uterine anomalies were of lower birth weight. Therefore, it can be concluded the women with congenital uterine anomalies had a higher risk of malpresentation and preterm deliveries. They also had a higher incidence of small for gestational age neonates.Conclusions: Presence of congenital uterine anomalies has adverse effect on obstetrical outcome. This knowledge warrants the need for a larger case control study to extrapolate these findings to the general population and also to recommend the need for universal Prenatal Screening for uterine anomalies so as to improve the obstetrical outcome in patients with uterine anomalies.

scholarly journals Uterine Rupture – Clinical Analysis of a Case Series in Riga Maternity Hospital

2017 ◽  
Vol 17 (1) ◽  
pp. 29-34
Author(s):  
Santa Smilga ◽  
Anna Miskova ◽  
Dace Rezeberga
Keyword(s):  
Cesarean Section ◽  
Maternal Death ◽  
Uterine Rupture ◽  
Hypovolemic Shock ◽  
Case Series ◽  
Maternity Hospital ◽  
Uterine Wall ◽  
Time Period ◽  
Case Series Study ◽  
Clinical Cases

Summary Introduction. Uterine rupture is a tearing of uterine wall during pregnancy or delivery. There are two types of uterine rupture described in literature: symptomatic (SUR) and asymptomatic (AUR) uterine rupture. In case of SUR there is a full thickness uterine wall tear which leads to clinical symptoms and high perinatal and maternal morbidity and mortality. In case of AUR the visceral peritoneum remains intact and it is typically diagnosed during Cesarean section. Rupture of previously intact uterus is very rare and is associated with extensive uterine damage, severe hemorrhage and in most cases leads to hysterectomy. Fetal complications include admission to neonatal intensive care unit, hypoxic - ischemic injury and death. Maternal complications include hemorrhage, hypovolemic shock, bladder injury, hysterectomy and maternal death. The incidence and prevalence of uterine rupture as well as the perinatal and maternal rate of complications in Latvia is unknown. Aim of the Study. Aim of the study is to analyze clinical cases of SUR and AUR, calculate the incidence and prevalence and detect the risk factors (RFs) and diagnostic difficulties of clinical cases which occurred in Riga Maternity Hospital from year 2010 to 2017. Material and methods. A case series study of 41 uterine ruptures which occurred in Riga Maternity Hospital from the 1st of January 2010 until the 31st of December 2016 was performed. An average birth rate for this time period was 6554 live births per year. Results. Over the time period 41 women with uterine rupture were diagnosed in Riga Maternity Hospital. AUR was diagnosed in 33 patients during Cesarean section. SUR occurred in seven patients, but in total there were eight cases of SUR, because one of the patients had a uterine rupture twice. SUR incidence in Riga Maternity Hospital is 1.7 per 10000 deliveries (8 per 45875 deliveries) and the prevalence is 0.0175%. In three cases SUR was diagnosed after labor and in five cases - during emergency laparotomy. SUR most frequently manifested with hypovolemic shock and/or acute abdomen. In two cases uterine defect was repaired and in six cases hysterectomy was performed. One patient had acute kidney injury and there was one case of maternal death. Nine babies were delivered and the Apgar score after the 1st minute was ≥ 7 in three cases and < 7 in three cases, but after the 5th minute it was ≥ 7 in five cases and <7 in one case. There were three intrauterine fetal demises. All the patients with either SUR or AUR had multiple RFs for uterine rupture. Conclusions. Uterine rupture is associated with multiple RFs. If trial of labor after Cesarean section is the preferred mode of delivery it is necessary to detect all of the RFs. Antenatal measurement of lower uterine segment thickness seems unreliable but further research should be carried out with statistical data analysis. For the safety of patients trial of vaginal delivery in patient with uterine scar should be performed in appropriately equipped and staffed medical facilities.

scholarly journals A review of malignant pleural mesothelioma in a large North East UK pleural centre

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Declan C. Murphy ◽  
Alexander Mount ◽  
Fiona Starkie ◽  
Leah Taylor ◽  
Avinash Aujayeb
Keyword(s):  
Malignant Pleural Mesothelioma ◽  
Survival Rates ◽  
Case Series ◽  
Pleural Mesothelioma ◽  
Retrospective Case ◽  
Pleural Thickening ◽  
North East ◽  
Total Cohort ◽  
Anti Cancer ◽  
One Year

AbstractObjectivesThe National Mesothelioma Audit 2020 showed Northumbria to have low rates of histopathological confirmation, treatment and one-year survival rates for malignant pleural mesothelioma (MPM). We hypothesized that an internal analysis over a 10-year period provides valuable insights into presentation, diagnosis, treatment and outcomes.MethodsA single-centre retrospective case series of all confirmed MPM patients between 1 January 2009 and 31 December 2019 was performed. Demographics, clinical, radiological and histopathological characteristics and outcomes were collected. Statistical analysis was performed using SPSS V26.0.ResultsA total of 247 patients had MPM. About 86% were male, mean age 75.7 years. Dyspnoea (77.4%) and chest pain (38.5%) were commonest symptoms. 64.9 and 71.4% had pleural thickening and effusion, respectively. About 86.8% had at least one attempt to obtain a tissue biopsy, but histopathological confirmation in only 108 (43.7%). About 66.3% with PS 0 and 1 (62.7% of total cohort) had at least one anti-cancer therapy. Death within 12 months was associated with disease progression within 6 months (p≤0.001). Chemotherapy (p≤0.001) and epithelioid histological subtype (p=0.01) were protective.ConclusionsThis study confirms known epidemiology of MPM, demonstrates variability in practices and highlights how some NMA recommendations are not met. This provides the incentive for a regional mesothelioma multi-disciplinary meeting.

Highly selective diversion with proactive leakage management after low anterior resection for rectal cancer

2021 ◽  
Author(s):  
K Talboom ◽  
I Vogel ◽  
R D Blok ◽  
S X Roodbeen ◽  
C Y Ponsioen ◽  
...  
Keyword(s):  
Low Anterior Resection ◽  
Case Series ◽  
Fecal Diversion ◽  
Single Center ◽  
Single Centre ◽  
Diverting Stoma ◽  
Faecal Diversion ◽  
One Year ◽  
Diversion Rate

Abstract In this single center case series with nine percent primary diversion, 86 of 94 patients alive and with complete follow-up at one year had a functioning anastomosis. Seventy-five of the initial 99 patients never had a stoma. Meaning: Highly selective fecal diversion in combination with proactive leakage management, low anastomoses can be preserved safely, and the majority of patients will be spared all disadvantages of a diverting stoma. In this single-centre case series, with a primary diversion rate of 9 per cent, 86 of 94 patients who were alive and had complete follow-up at 1 year had a functioning anastomosis. Seventy-five of the initial 99 patients never had a stoma. The results indicate that, with highly selective faecal diversion in combination with proactive leakage management, low anastomoses can be preserved safely, and the majority of patients will be spared the disadvantages of a diverting stoma.

scholarly journals One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

2021 ◽  
Vol 18 (10) ◽  
pp. 5104
Author(s):  
Iván Area ◽  
Henrique Lorenzo ◽  
Pedro J. Marcos ◽  
Juan J. Nieto
Keyword(s):  
Intensive Care Unit ◽  
Hospital Admissions ◽  
Age Groups ◽  
Age Group ◽  
Nw Spain ◽  
The Past ◽  
Global View ◽  
Time Period ◽  
Key Variables ◽  
One Year

In this work we look at the past in order to analyze four key variables after one year of the COVID-19 pandemic in Galicia (NW Spain): new infected, hospital admissions, intensive care unit admissions and deceased. The analysis is presented by age group, comparing at each stage the percentage of the corresponding group with its representation in the society. The time period analyzed covers 1 March 2020 to 1 April 2021, and includes the influence of the B.1.1.7 lineage of COVID-19 which in April 2021 was behind 90% of new cases in Galicia. It is numerically shown how the pandemic affects the age groups 80+, 70+ and 60+, and therefore we give information about how the vaccination process could be scheduled and hints at why the pandemic had different effects in different territories.

Survival With Respect to Morphology in Pulmonary Atresia and Intact Ventricular Septum in Sweden

2021 ◽  
Vol 12 (1) ◽  
pp. 27-34
Author(s):  
Stina Manhem ◽  
Katarina Hanséus ◽  
Håkan Berggren ◽  
Britt-Marie Ekman-Joelsson
Keyword(s):  
Pulmonary Atresia ◽  
Early Time ◽  
Ventricular Septum ◽  
Intact Ventricular Septum ◽  
Early Group ◽  
Time Period ◽  
Medical Reports ◽  
One Year ◽  
Survival Risk ◽  
Late Group

Background: Patients born with pulmonary atresia and intact ventricular septum represent a challenge to pediatric cardiologists. Our objective was to study changes in survival with respect to morphology in all children born with pulmonary atresia and intact ventricular septum in Sweden during 36 years. Methods: A retrospective, descriptive study based on medical reports and echocardiographic examinations consisting of those born between 1980 and 1998 (early group) and those born between 1999 and 2016 (late group). Results: The cohort consists of 171 patients (early group, n = 86 and late group, n = 85) yielding an incidence of 4.35 and 4.46 per 100,000 live births, respectively. One-year survival in the early group was 76% compared to 92% in the late group ( P = .0004). For patients with membranous atresia, one-year survival increased from 78% to 98%, and for muscular pulmonary atresia, from 68% to 85%. In patients with muscular pulmonary atresia and ventriculocoronary arterial communications, there was no significant increase in survival. Risk factors for death were being born in the early time period hazard ratio (HR), 6; 95% CI (2.33-14.28) P = .0002, low birth weight HR, 1.26; 95% CI (1.14-1.4) P < .0001 and having muscular pulmonary atresia HR, 3.74; 95% CI (1.71-8.19) P = .0010. Conclusion: The incidence of pulmonary atresia and intact ventricular septum remained unchanged during the study period. Survival has improved, especially for patients with membranous pulmonary atresia, while being born with muscular pulmonary atresia is still a risk factor for death. To further improve survival, greater focus on patients with muscular pulmonary atresia and ventriculocoronary arterial communications is required.

scholarly journals One-year outcomes of fixed-dosing Aflibercept therapy for pre treated and naive polypoidal choroidal vasculopathy patient

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hun Gu Choo ◽  
Jin Hae Lee ◽  
Hyun Sub Oh ◽  
Soon Hyun Kim ◽  
Yong Sung You ◽  
...  
Keyword(s):  
Polypoidal Choroidal Vasculopathy ◽  
Vision Loss ◽  
Case Series ◽  
Age Related Macular Degeneration ◽  
Research Information ◽  
Age Related ◽  
Case Series Study ◽  
Treatment Naïve ◽  
One Year ◽  
Choroidal Vasculopathy

Abstract Background Polypoidal choroidal vasculopathy (PCV) is a type of age-related macular degeneration that can cause permanent vision loss. The purpose of this paper was to report the one-year outcomes of fixed-dosing aflibercept therapy for the treatment of PCV. Methods This was a prospective, single-arm, interventional case series study of 25 PCV patients; 12 pre-treated and 13 treatment-naïve patients. The patients were treated and monitored for 12 months. Each patient was administered with an aflibercept (2.0 mg) injection every month for the first 3 months (the loading phase), and thereafter, once every 2 months. At every follow-up visit, best-corrected visual acuity (BCVA) test, fundus examination, and optical coherence tomography for measuring the central subfield macular thickness (CSMT) were performed. Fluorescein and indocyanine green angiography were conducted at baseline and at 4 and 12 months. Results After 12 months of aflibercept therapy, the mean BCVA of the patients significantly improved from 65.48 letters at baseline to 69.91 letters (p=0.001), and the CSMT significantly decreased from 406.92 um at baseline to 276.12 um (p< 0.001). Additionally, ten patients (40%) showed complete polyp regression. The treatment-naïve patients showed a statistically significant improvement in BCVA from 66.58 letters at baseline to 76.36 letters at 12 months, and a significant decrease in CSMT, from 462 to 243 um. In the pre-treated group, there was no change in BCVA (64.46 letters), and the decrease in CSMT from 356.08 to 303.69 um was not statistically significant. Conclusions The fixed-dosing aflibercept regimen is effective for treating patients with PCV and is more effective in treatment-naïve patients than in pre-treated patients. Trial registration Clinical Research Information Service (CRiS), Republic of Korea. Identifer: KCT0005798, Registered: Jan 20, 2021. Retrospectively registered, URL: https://cris.nih.go.kr/cris/en/search/search_result_st01.jsp?seq=18546

scholarly journals Platypnoea–orthodeoxia syndrome induced by short-term weight loss: a case series

2020 ◽  
Author(s):  
Yudai Tamura ◽  
Tomohiro Sakamoto
Keyword(s):  
Weight Loss ◽  
Septal Defect ◽  
Case Series ◽  
Transoesophageal Echocardiography ◽  
Sitting Position ◽  
Short Time Period ◽  
Time Period ◽  
Uncommon Condition ◽  
The Right ◽  
Short Time

Abstract Background Platypnoea–orthodeoxia syndrome (POS) is an uncommon condition characterized by dyspnoea and arterial desaturation in the standing or sitting position that improves in the supine position. Case summary We report two cases of POS caused by an atrial septal defect (ASD) and a patent foramen ovale (PFO). Both cases reported a recent decrease in body weight of more than 10 kg in a short time period. Transoesophageal echocardiography (TOE) with agitated saline bubble study revealed and a large amount of contrast bubble through the ASD (Patient 1) or the PFO (Patient 2) from the right atrium to the left atrium in the sitting position. Both patients were diagnosed by the finding of positional dyspnoea and the results of TOE using agitated saline bubble contrast. Discussion Taken together, their presentations suggest that weight loss in a short time period could be a pathogenic factor for POS.

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