scholarly journals Boston keratoprosthesis type 1 - indication, complication and visual outcomes

2017 ◽  
Vol 5 (5) ◽  
pp. 1903
Author(s):  
Kritika Raina ◽  
Alka Gupta
Keyword(s):  
Poor Prognosis ◽  
Corneal Neovascularization ◽  
Corneal Graft ◽  
Retention Rates ◽  
Type I ◽  
Medical College ◽  
Number Of Patients ◽  
Department Of Ophthalmology ◽  
End Stage

Background: Diseases affecting the cornea are a major cause of blindness all over the world, second only to cataract in overall importance. In India, there are approximately 6.8 million people who have corneal blindness with vision less than 6/60 in at least one eye, and of these, about 1 million have bilateral corneal blindness.Methods: The study was conducted in upgraded department of ophthalmology, L.L.R.M. Medical College, Meerut, India from January 2014 to June 2015. It was prospective interventional study. Included those patients who have Failed corneal graft with poor prognosis for further grafting, multiple corneal graft failure, having nearly total corneal neovascularization, vision less than 6/60 with associated other complications in better eye and no vision in opposite eye and Healed Chemical burn and those patients who has end stage glaucoma or RD (retinal detachment), defective perceptions and projection of light and not willing for the procedure.Results: A total of 20 patients were enrolled for the study which were followed up and assessed over 12 months. It was observed that maximum number of patients were in the age group of 41-60 years (45%) and in the >60 years group are minimum (20%). Among these 14 cases (70%) were male and 6 cases (30%) were female.Conclusions: The Boston type 1 keratoprosthesis provides visual recovery for eyes with multiple PK failures or with poor prognosis for primary PK, showing excellent retention rates. Most of the cases had a significant improvement in vision after Boston type I KPro implantation.

scholarly journals A comparative study of preoperative and postoperative hearing after type I tympanoplasty using temporalis fascia graft at Dr. B. R. Ambedkar Medical College, Bengaluru

2020 ◽  
Vol 6 (7) ◽  
pp. 1258
Author(s):  
Muniraju M. ◽  
Smita Hegde
Keyword(s):  
Disease Duration ◽  
Type I ◽  
Temporalis Fascia ◽  
Hearing Gain ◽  
Medical College ◽  
Type 1 Tympanoplasty ◽  
Fascia Graft ◽  
Cortical Mastoidectomy ◽  
A Prospective Study

<p class="abstract"><strong>Background:</strong> The objective of the study was to identify the factors which significantly influence type 1 tympanoplasty success.</p><p class="abstract"><strong>Methods:</strong> A prospective study was performed on 30 patients who underwent type 1 tympanoplasty via underlay technique using temporalis fascia graft from December 2017 to September 2019 in a teaching hospital. Outcome measures were graft uptake rate and hearing gain. The factors assessed were the age and sex, preoperative condition of the ipsilateral and contralateral ears, perforation size, presence of tympanosclerosis, and whether simultaneous cortical mastoidectomy was performed.  </p><p class="abstract"><strong>Results:</strong> None of the factors proved to have a significant influence on tympanic membrane closure or hearing gain.</p><p class="abstract"><strong>Conclusions:</strong> The success rate of a type 1 tympanoplasty is dependent on the skills of the surgeon and the type of graft used. Age, sex, laterality of the disease, duration of dry ear, size of the perforation, presence of tympanosclerosis and simultaneous cortical mastoidectomy have no bearing on hearing gain.</p>

scholarly journals A clinicopathological study of vernal conjunctivitis in urban and rural areas of Eastern India: A hospital based study

2018 ◽  
Vol 6 (3) ◽  
pp. 966
Author(s):  
Suman Adhikari ◽  
Asok Kumar Naskar ◽  
Samarendra Kabasi ◽  
Sujata Deb ◽  
R. K. Deb ◽  
...  
Keyword(s):  
Rural Areas ◽  
Vernal Keratoconjunctivitis ◽  
Treatment Groups ◽  
Medical College ◽  
Biopsy Specimens ◽  
Number Of Patients ◽  
Department Of Ophthalmology ◽  
Conjunctival Biopsy ◽  
Urban And Rural Areas ◽  
Vernal Conjunctivitis

Background: Vernal keratoconjunctivitis (VKC) is a relatively rare, chronic form of ocular allergy that can potentially cause severe visual complications.Methods: The present study was carried out amongst the patients suffering from vernal conjunctivitis and attending the Outpatient Department of Ophthalmology of Mata Gujri Memorial Medical College & Lions Seva Kendra Hospital, Kishanganj (Bihar). The conjunctiva and cornea were examined for any complication of the disease. The patients were categorized into two treatment groups, each group treated with one topical drug. As the total number of patients in the study was 100, each treatment group consisted of 50 patients, one group of patients was treated with 0.05% azelastine eye drop and the other group treated with 2% sodium cromoglycate eye drop.Results: Greater incidence during the period from March to June (59%) and the highest number in the month of May (18%). Of the 100 patients in the study group, the largest group of 89 patients presented with limbal vernal conjunctivitis; 7 patients presented with palpebral vernal conjunctivitis and 4 patients suffered from a mixed type (both limbal and palpebral) type of the disease.Conclusions: Examination of the conjunctival biopsy specimens of the patients showed chronic nonspecific inflammatory reaction, mostly confined to the subepithelial region. Patients in both groups showed dramatic results of the treatment proving the efficacy of steroids. 

scholarly journals Endoscopic malleus button hole myringoplasty

2020 ◽  
Vol 6 (2) ◽  
pp. 268
Author(s):  
Sumit Prinja ◽  
Gurbax Singh ◽  
Jai Lal Davessar ◽  
Suchina Parmar ◽  
Ramandeep Singh
Keyword(s):  
Ear Surgery ◽  
Middle Ear Mucosa ◽  
Graft Placement ◽  
Medical College ◽  
Number Of Patients ◽  
Tube Function ◽  
New Perspective ◽  
Endoscopic Tympanoplasty ◽  
Bony Overhang

<p class="abstract"><strong>Background:</strong> Myringoplasty or type-1 tympanoplasty is surgical procedure that is used for repair of the tympanic membrane. The result outcome of myringoplasty depends on several variables such as method of tympanoplasty taken whether endoscopic and microscopic, of size of perforation, bony overhang, eustachian tube function, state of the middle ear mucosa, degree of pneumatization of mastoid and technique of graft placement.</p><p class="abstract"><strong>Methods:</strong> Our study was conducted at G.G.S. Medical College, Faridkot from January 2017 to April 2018. Patients were taken for endoscopic tympanoplasty and graft was placed with buttonhole technique. Results were compared in form of preoperative audiometry and post-operative audiometry done after 3 months.  </p><p class="abstract"><strong>Results:</strong> In our study patients done with endoscopic tympanoplasty with buttonhole technique graft placement showed postoperative audiometry with decreased air bone gap   till 10 db in maximum number of patients and 97% patents with graft uptake.</p><p class="abstract"><strong>Conclusions:</strong> The use of endoscopes has brought a new perspective to ear surgery. The use of endoscopes along with different technique as mentioned of placing graft to prevent all the complications.</p>

scholarly journals Clinical study of central serous chorioretinopathy presenting in a tertiary care centre

2019 ◽  
Vol 7 (11) ◽  
pp. 4200
Author(s):  
Ramamani Dalai ◽  
Rajashree Rout ◽  
Manjula Pradhan ◽  
Prasanta Kumar Nanda
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Tertiary Care ◽  
Population Based ◽  
Tertiary Care Centre ◽  
Population Based Study ◽  
Medical College ◽  
Number Of Patients ◽  
Department Of Ophthalmology ◽  
Common Causes ◽  
The Common

Background: Central Serous chorioretinopathy (CSCR) is one of the common causes of visual handicap affecting young people of highly intellectual professionals at the peak of their career which can lead to irrecoverable loss of vision.Methods: The present prospective observational population-based study was conducted in the Department of Ophthalmology, S.C.B. Medical College, Cuttack, Odisha from October 2013 to September 2015. The total number of patients attended the Outpatient Department (OPD) during the study period were 1,83,199. Amongst which 123 patients diagnosed to have CSCR were selected for the present study.Results: Incidence of CSCR during in this study period was 0.06%. The age group most commonly affected was 31 to 40 years. Males were affected 7 times more commonly than females. Increased incidence was noticed in bank employees (21.1 %) and IT professionals (17.8%).Conclusions: There was increased incidence of the disease in people under stressful life condition.

Comparative Study of effectiveness of mobilization with movement (MWM) and End range mobilization (ERM) techniques in frozen shoulder

2018 ◽  
Vol 4 (4) ◽  
pp. 519-522
Author(s):  
Jeyakumar S ◽  
Jagatheesan Alagesan ◽  
T.S. Muthukumar
Keyword(s):  
Range Of Motion ◽  
Frozen Shoulder ◽  
Type I ◽  
Mean Values ◽  
Functional Activities ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Frozen shoulder is disorder of the connective tissue that limits the normal Range of motion of the shoulder in diabetes, frozen shoulder is thought to be caused by changes to the collagen in the shoulder joint as a result of long term Hypoglycemia. Mobilization is a therapeutic movement of the joint. The goal is to restore normal joint motion and rhythm. The use of mobilization with movement for peripheral joints was developed by mulligan. This technique combines a sustained application of manual technique “gliding” force to the joint with concurrent physiologic motion of joint, either actively or passively. This study aims to find out the effects of mobilization with movement and end range mobilization in frozen shoulder in Type I diabetics. Materials and Methods: 30 subjects both male and female, suffering with shoulder pain and clinically diagnosed with frozen shoulder was recruited for the study and divided into two groups with 15 patients each based on convenient sampling method. Group A patients received mobilization with movement and Group B patients received end range mobilization for three weeks. The outcome measurements were SPADI, Functional hand to back scale, abduction range of motion using goniometer and VAS. Results: The mean values of all parameters showed significant differences in group A as compared to group B in terms of decreased pain, increased abduction range and other outcome measures. Conclusion: Based on the results it has been concluded that treating the type 1 diabetic patient with frozen shoulder, mobilization with movement exercise shows better results than end range mobilization in reducing pain and increase functional activities and mobility in frozen shoulder.

Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat

MEDISAINS ◽  
2020 ◽  
Vol 18 (1) ◽  
pp. 19
Author(s):  
Fairuz Fairuz ◽  
Hasna Dewi ◽  
Humaryanto Humaryanto
Keyword(s):  
Blood Glucose ◽  
Side Effects ◽  
Type I Diabetes ◽  
Langerhans Cell ◽  
Diabetic Rat ◽  
Type I ◽  
Antidiabetic Effect ◽  
Glucose Levels ◽  
Blood Glucose Levels

Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance. Salung leaf herb (Psychotria malayana Jack) reported used in traditional societies as a treatment for diabetes. However, the scientific proof of this plant for diabetes treatment is still lacking.Objective: To evaluate the antidiabetic effect of the P. malayana jack in induced type 1 diabetic rats by assessing blood glucose level and pancreatic cells in white rats.Methods: Alloxan used to induce type I diabetes. Rats randomly divided into six groups. A Group P1 received 250 mg/kg BW; group P2 received 500 mg/kg BW, group P3 received 1000 mg/kg BW. While group 4 basal received no treatment, group 5 received distilled water as a negative control, and group 6 received glibenclamide as a positive control. Medications are given for six days. Glucose levels were measured, and observation of pancreatic Langerhans cell damages.Results:  A decrease in blood glucose levels observed in all treatment groups. The most significant reduction (49.76%; 1000 mg/kg BW) occurred in the P3 group. Morphological features of pancreatic Langerhans cell damage were slightly high in the P1 group.Conclusion: P. malayana Jack can consider having an antidiabetic effect in a type 1 diabetic rat by reducing blood glucose levels.

Study on Knowledge and Prevalence of Computer Vision Syndrome among Computer Operators in Nobel Medical College Teaching Hospital, Biratnagar, Nepal

2020 ◽  
Vol 9 (2) ◽  
pp. 45-49
Author(s):  
Pramod Sharma Gautam ◽  
Uday Chandra Prakash ◽  
Subreena Dangol
Keyword(s):  
Computer Vision ◽  
Teaching Hospital ◽  
Human Life ◽  
College Teaching ◽  
Extended Period ◽  
Visual Display ◽  
Work Place ◽  
Medical College ◽  
Computer Vision Syndrome ◽  
Department Of Ophthalmology

Background: The eye and vision related problems that results from continuous use of computers and other visual display terminals for extended period of time leads to computer vision syndrome. Due to rapid digitalization in human life, the risk of developing it has also increased in many folds. So, with an aim of determining the prevalence and level of awareness of computer vision syndrome among computer users along with their attitude and practices to prevent it, this study was conducted in the office employees who use computer for a considerable period of time. Materials and Methods: A hospital based observational descriptive study was conducted in the out-patient department of Ophthalmology in Nobel Medical College and Teaching Hospital, Biratnagar, where 105 employees working in different work stations of same institution were enrolled. A questionnaire and the clinical findings were used to collect data. Results: About 80% of the employees were using computer for about (8-11) hours per day. Prevalence of computer vision syndrome noted was (92.4%) with low level of knowledge (85.7%) about it. About 45% of them wore glasses for their refractive errors but attitude and practices in work place to prevent the bad effects of using visual display terminals were found to be lacking (53.3%). Burning sensation in the eye, headache, ocular irritation and itching and neck, shoulder or back pain were the common symptoms. Around (60-70)% of the eyes tested positive for dry eye. Conclusion: Lack of awareness of computer vision syndrome and lack of personal protective measures were associated with its high level of prevalence.  

Coronary sinus catalase and ceruloplasmin levels predict all-cause mortality in patients with end-stage heart failure awaiting heart transplantation

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
W Szczurek ◽  
M Gasior ◽  
M Skrzypek ◽  
G Kubiak ◽  
A Kuczaj ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Transplantation ◽  
Coronary Sinus ◽  
Public Institution ◽  
Funding Source ◽  
Organ Shortage ◽  
Number Of Patients ◽  
End Stage ◽  
Medical University

Abstract   Background, As a consequence of the worldwide increase in life expectancy and due to significant progress in the pharmacological and interventional treatment of heart failure (HF), the proportion of patients that reach an advanced phase of disease is steadily growing. Hence, more and more numerous group of patients is qualified to the heart transplantation (HT), whereas the number of potential heart donors has remained invariable since years. It contributes to deepening in disproportion between the demand for organs which can possibly be transplanted and number of patients awaiting on the HT list. Therefore, accurate identification of patients who are most likely to benefit from HT is imperative due to an organ shortage and perioperative complications. Purpose The aim of this study was to identify the factors associated with reduced survival during a 1.5-year follow-up in patients with end-stage HF awating HT. Method We propectively analysed 85 adult patients with end-stage HF, who were accepted for HT at our institution between 2015 and 2016. During right heart catheterization, 10 ml of coronary sinus blood was additionally collected to determine the panel of oxidative stress markers. Oxidative-antioxidant balance markers included glutathione reductase (GR), glutathione peroxidase (GPx), glutathione transferase (GST), superoxide dismutase (SOD) and its mitochondrial isoenzyme (MnSOD) and cytoplasmic (Cu/ZnSOD), catalase (CAT), malondialdehyde (MDA), hydroperoxides lipid (LPH), lipofuscin (LPS), sulfhydryl groups (SH-), ceruloplasmin (CR). The study protocol was approved by the ethics committee of the Medical University of Silesia in Katowice. The endpoint of the study was mortality from any cause during a 1.5 years follow-up. Results The median age of the patients was 53.0 (43.0–56.0) years and 90.6% of them were male. All included patients were treated optimally in accordance with the guidelines of the European Society of Cardiology. Mortality rate during the follow-up period was 40%. Multivariate logistic regression analysis showed that ceruloplasmin (odds ratio [OR] = 0.745 [0.565–0.981], p=0.0363), catalase (OR = 0.950 [0.915–0.98], p=0.0076), as well as high creatinine levels (OR = 1.071 [1.002–1.144], p=0.0422) were risk factors for death during 1.5 year follow-up. Conclusions Coronary sinus lower ceruloplasmin and catalase levels, as well as higher creatinine level are independently associated with death during 1.5 year follow-up. Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): Medical University of SIlesia, Katowice, POland

Sign in / Sign up

Export Citation Format

Share Document