scholarly journals Takayasu arteritis: a comprehensive review of literature

Author(s):  
Ravin K. Bishnoi ◽  
Shivani Devi ◽  
Shivani Rai ◽  
Gunjot .

Takayasu arteritis is an inflammatory pulseless disease of large arteries with unknown etiology which advances in three stages i.e. early systemic, vascular, and burnout stage. It is more prevalent in Asian women of childbearing age. Hypertension, fever, weight loss, arthralgia, limb claudication, light-headedness, and arterial pain are common manifestations. Angiography is a gold standard test to evaluate TA. There is no reliable serological marker has been identified. Control on the inflammatory process and hypertension are two imperative angles to treat the disease. Steroids are most used. Reconstructive surgeries are limited to severe and stenotic lesions. This review aims to report comprehensive evidence about Takayasu arteritis. We conducted an integrative review of theoretical and empirical publications reporting epidemiology, etiopathogenesis, classification, diagnostic evaluation, and management of TA. The authors searched PubMed, Embase, and Scopus until March 2020.  A total of 1104 records found, we included 37 papers for review after reading the articles. Remaining was excluded because of no innovative content, insufficient details, and no clear endpoints. This review of the literature presents comprehensive evidence in all fields of TA. Still, large areas need to be studied for better management of patients with TA.

2017 ◽  
Vol 51 (4) ◽  
pp. 195-198 ◽  
Author(s):  
Sarah Soo-Hoo ◽  
Jenny Seong ◽  
Brandon R. Porten ◽  
Nedaa Skeik

Takayasu arteritis is a rare, chronic vasculitis of unknown etiology characterized by inflammation of the aorta and its main branches. Although Takayasu arteritis mostly affects women of childbearing age, there is a paucity in the literature on pregnancy associated with Takayasu arteritis. Pregnant patients are at increased risk of cardiovascular complications, including hypertension and congestive heart failure, which may jeopardize both maternal and fetal outcomes. Furthermore, optimal management has not yet been established for pregnant patients with Takayasu arteritis, posing a clinical challenge. We present a case of a young woman with Takayasu arteritis whose symptoms and disease activity improved during 2 pregnancies. Although her first pregnancy was complicated with preeclampsia, gestational diabetes, and preterm vaginal delivery, her second pregnancy was uneventful. This case provides a rare glimpse of Takayasu arteritis in pregnancy and highlights the challenges of medical management in gravid patients.


2021 ◽  
Author(s):  
Liheng Tang ◽  
◽  
Jin Xian ◽  
Ye Zhang ◽  
Changyun Zhang ◽  
...  

Review question / Objective: How effective is acupuncture in treating melasma compared to conventional treatment? Condition being studied: Melasma is a common acquired hyperpigmentation of the skin. The clinical manifestations are light brown or dark brown patches symmetrically distributed on the cheeks, forehead and mandibular with different shades and unclear borders. Melasma particularly affects women during menstruation, especially in thirties and forties Asian women. The incidence of Asian women of childbearing age is as high as 30%. Current treatments for melasma include topical drugs, chemical peeling agents, laser and light treatments, and systemic drugs. Despite the strong demand for treatment, the treatment of melasma is still very challenging, the results are inconsistent, and the recurrence rate is almost constant.


Author(s):  
Kamal Bhatt ◽  
Parveen Jindal ◽  
Sudesh Gupta ◽  
Shalini Suri

ABSTRACT Takayasu arteritis is a large-vessel vasculitis most commonly affecting women of childbearing age. The disease process is usually slow and smoldering, presenting over months to years. Digital gangrene is an uncommon manifestation of Takayasu arteritis because of the formation of good collateral circulation. Similarly, although pulmonary artery involvement is well described, pulmonary parenchymal involvement is very rare. We are reporting a case of a young girl with Takayasu arteritis presenting with digital gangrene and pulmonary consolidation, which was treated successfully with a combination of aggressive systemic immunosuppression and anti-coagulants. The possible mechanism for gangrene along with the confounding diagnostic possibility of co-existing tuberculosis have been discussed.


2019 ◽  
Vol 10 ◽  
Author(s):  
Minghua Tang ◽  
Daniel N. Frank ◽  
Antoinette Tshefu ◽  
Adrien Lokangaka ◽  
Shivaprasad S. Goudar ◽  
...  

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Malikul Chair ◽  
Bambang Setyohadi ◽  
RM Suryo Anggoro ◽  
Anna Ariane

Takayasu arteritis (TA) is a systemic, inflammatory large-vessel vasculitis of unknown etiology that most commonly affects women of childbearing age. It involves the aorta and its major branches. The main abnormalities found in this disease are vascular ischemic signs/symptoms including claudication, carotid bruit, weak distal pulsation. Hereby we report a case a 25-year-old unmarried female complained a recurrent left arm pain, worsening when she did her work as a doctor. Formerly, she had experienced intermittent bilateral leg pain for four years with strange sound coming from inside her neck. She was hospitalized half a year ago due to acute limb ischemic and she was diagnosed with TA after the imaging showed multiple stenosis in large arteries including bilateral neck area, shoulder area, abdominal aorta, and right renal artery. The inferior right extremity biopsy showed the histologist result of erythema nodosum appearance. Cuantitative C reactive protein (CRP): 19,8, erythrocyte sedimen rate (ESR): 53. The others laboratory data to exclude differential diagnosis are unremarkable. This report demonstrates the importance of diagnostic approach in rare case of Takayasu’s arteritis patients. Keyword: Diagnostic; Vasculitis, Takayasu Arteritis


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