scholarly journals Takayasu Arteritis : Diagnostic Approach

2018 ◽  
Vol 10 (2) ◽  
Author(s):  
Malikul Chair ◽  
Bambang Setyohadi ◽  
RM Suryo Anggoro ◽  
Anna Ariane
Keyword(s):  
Takayasu Arteritis ◽  
Erythema Nodosum ◽  
Laboratory Data ◽  
Diagnostic Approach ◽  
Leg Pain ◽  
Unknown Etiology ◽  
C Reactive Protein ◽  
Childbearing Age ◽  
Reactive Protein ◽  
Arm Pain

Takayasu arteritis (TA) is a systemic, inflammatory large-vessel vasculitis of unknown etiology that most commonly affects women of childbearing age. It involves the aorta and its major branches. The main abnormalities found in this disease are vascular ischemic signs/symptoms including claudication, carotid bruit, weak distal pulsation. Hereby we report a case a 25-year-old unmarried female complained a recurrent left arm pain, worsening when she did her work as a doctor. Formerly, she had experienced intermittent bilateral leg pain for four years with strange sound coming from inside her neck. She was hospitalized half a year ago due to acute limb ischemic and she was diagnosed with TA after the imaging showed multiple stenosis in large arteries including bilateral neck area, shoulder area, abdominal aorta, and right renal artery. The inferior right extremity biopsy showed the histologist result of erythema nodosum appearance. Cuantitative C reactive protein (CRP): 19,8, erythrocyte sedimen rate (ESR): 53. The others laboratory data to exclude differential diagnosis are unremarkable. This report demonstrates the importance of diagnostic approach in rare case of Takayasu’s arteritis patients. Keyword: Diagnostic; Vasculitis, Takayasu Arteritis

scholarly journals Chondrosternal Arthritis in Infant: An Unusual Entity

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Athina Nikolarakou ◽  
Dana Dumitriu ◽  
Pierre-Louis Docquier
Keyword(s):  
Clinical Symptoms ◽  
Therapeutic Option ◽  
White Blood Cells ◽  
Laboratory Data ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
History Of ◽  
Local Tenderness ◽  
Wait And See

Primary arthritis of chondrosternal joint is very rare and occurs in infants less than 18 months of age. Presentation is most often subacute but may be acute. Child presents with a parasternal mass with history of fever and/or local signs of infection. Clinical symptoms vary from a painless noninflammatory to a painful mass with local tenderness and swelling, while fever may be absent. Laboratory data show low or marginally raised levels of white blood cells and C-reactive protein, reflecting, respectively, the subacute or acute character of the infection. It is a self-limiting affection due to the adequate immune response of the patient. Evolution is generally good without antibiotherapy with a progressive spontaneous healing. A wait-and-see approach with close follow-up in the first weeks is the best therapeutic option.

APPENDECTOMY IN CHILDREN WITH ACUTE RHEUMATIC FEVER

PEDIATRICS ◽  
1969 ◽  
Vol 43 (4) ◽  
pp. 573-577
Author(s):  
Jer-Shoung Lin ◽  
Ramon Rodriguez-Torres
Keyword(s):  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Acute Appendicitis ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Laboratory Data ◽  
Initial Symptom ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
The Right

Clinical and laboratory data on five patients with appendectomy, later proved to have acute rheumatic fever, are presented in detail. The findings indicate that abdominal pain simulating acute appendicitis can be presented as the only initial symptom in acute rheumatic fever. Awareness and knowledge of the presence of clues-high fever, rapid sedimentation rate, prolonged P-R interval, and 4 plus C-reactive protein-usually help to make the differential diagnosis. However, if doubt remains, the right approach is to go ahead with surgery since these patients tolerate anesthesia and laparotomy very well.

scholarly journals Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Espen Benjaminsen ◽  
Anne Reigstad ◽  
Vanja Cengija ◽  
Vibke Lilleby ◽  
Maria Carlsson
Keyword(s):  
Carotid Artery ◽  
Takayasu Arteritis ◽  
Common Carotid Artery ◽  
Right Hemisphere ◽  
Latent Tuberculosis ◽  
C Reactive Protein ◽  
Laboratory Findings ◽  
Case Presentation ◽  
Reactive Protein ◽  
The Right

Introduction. Takayasu arteritis is a rare disease affecting the aorta and its main branches, causing arterial claudication and end-organ ischemia, including stroke. The etiology is unknown but is believed to be autoimmune. An association between Takayasu arteritis and tuberculosis has been suggested, but the possible relation is unclear.Case Presentation. A 15-year-old Somali boy was diagnosed with latent tuberculosis. He had a lesion in the right lung, and both the tuberculin skin test by the Mantoux method and Quantiferon GOLD test turned out positive. After he suffered a cerebral infarct in the right hemisphere, childhood Takayasu arteritis was diagnosed. The diagnosis was based on diagnostic imaging showing a high-grade stenosis of the origin of the right common carotid artery, an occluded common carotid artery on the left side, a circumferential thickening of the vessel walls in the right and left common carotid artery, and laboratory findings with elevated C-reactive protein.Conclusion. Takayasu arteritis is an uncommon cause of stroke. It should however be kept in mind as a cause of cerebrovascular disease, especially in the young.

scholarly journals Evolution of CT patterns in novel coronavirus (2019-nCoV) pneumonia in relation to clinical and laboratory data

2021 ◽  
Vol 12 (2) ◽  
pp. 49-58
Author(s):  
А. А. Oganesyan ◽  
I. V. Shrainer ◽  
V. N. Vinogradov ◽  
E. S. Pershina ◽  
E. G. Koshelev ◽  
...  
Keyword(s):  
Prognostic Value ◽  
Patient Management ◽  
Dynamic Change ◽  
Laboratory Data ◽  
Good Prognosis ◽  
Organizing Pneumonia ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Novel Coronavirus ◽  
Ct Studies

Introduction. The CT patterns of coronavirus pneumonia are clear and represent certain pathomorphosis at the period of coronavirus pandemic. However, there are a lot of questions about influence of CT-patterns and their dynamic change on a disease’s severity. The aim of the study. To evaluate the dynamics of pulmonary CT changes of novel coronavirus (2019-nCoV) pneumonia in relation to clinical and laboratory data. Materials and methods. CT studies in dynamics of 108 patients with a of novel coronavirus (2019-nCoV) pneumonia were analyzed. The first CT study was performed on admission (6,7±4,1 days of the disease), the first control CT on 11,1±4,9 days of the disease, and the second CT control was performed on 16,7±5,6 days of the disease. Results. The volume of the lesion and the predominant CT symptom at admission did not affect the prognosis. However, changes in the repeated CT study had a high prognostic value. Thus, the occurrence of a pattern of organizing pneumonia during repeated study is associated with a good prognosis, while an increase in the zones of «crazy paving» and a larger volume of damage are unfavorable prognostic signs. An increase in the volume of changes in the type of ground glass and «crazy paving» correlated with increased levels of C-reactive protein, lactate dehydrogenase, and lymphopenia. Conclusion. Data from CT studies in dynamics for novel coronavirus (2019-nCoV) pneumonia have a prognostic value and, in combination with clinical and laboratory data, can influence decision-making on patient management.

scholarly journals Clinical features of osteoarthritis in patients with metabolic syndrome

2017 ◽  
Vol 89 (5) ◽  
pp. 65-68 ◽  
Author(s):  
L V Vasilyeva ◽  
D I Lakhin
Keyword(s):  
Metabolic Syndrome ◽  
Negative Impact ◽  
Laboratory Data ◽  
International Diabetes Federation ◽  
Pain Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Factor Α ◽  
Necrosis Factor

Aim. To estimate clinical and laboratory parameters in patients with osteoarthritis (OA) and in those with OA and metabolic syndrome (MS). Subjects and methods. 164 patients with OA were examined and divided into 2 groups of 82 people: a study group (patients with MS) and a control one (those without MS). OA was defined according to the diagnostic criteria described by R.D. Althmann (1995). MS was identified based on the criteria developed by the International Diabetes Federation (2005). The location of affected and swollen joints was determined according to the Richie index; the intensity of pain syndrome was measured by a visual analogue scale at rest and on movement; the WOMAC and Lequesne indexes were estimated in the patients. Erythrocyte sedimentation rate and C-reactive protein and tumor necrosis factor-α levels were determined from laboratory data. Results. In the MS group, the frequency of joint injuries at various sites, the prevalence of synovitis, and the intensity of pain and inflammation were significantly higher than in the non-MS group. Conclusion. The negative impact of MS on the clinical picture of OA can be inferred by the findings.

scholarly journals Age-Related Differences in the Association between Plasma High-Sensitivity C-Reactive Protein and Noncalcified or Mixed Coronary Atherosclerotic Plaques

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tiewei Li ◽  
Ning Chen ◽  
Zhengan Liu ◽  
Zhiming Shan ◽  
Geng Dong ◽  
...  
Keyword(s):  
Older Adults ◽  
Multiple Logistic Regression Analysis ◽  
Laboratory Data ◽  
High Sensitivity ◽  
Coronary Plaque ◽  
Control Group ◽  
C Reactive Protein ◽  
Old Adults ◽  
Reactive Protein ◽  
Age Related

Background. Previous studies have demonstrated that plasma high-sensitivity C-reactive protein (hsCRP) was the predictor for unstable coronary plaque. Patients with noncalcified plaque (NCP) or mixed plaque (MP) have a higher risk of poor outcomes. However, the association between hsCRP and the presence of NCP or MP (NCP/MP) in old adults remains unclear, and if present, whether there exist differences between young and old adults remain unknown. Thus, the aim of this study was to investigate the role of hsCRP in predicting the presence of NCP/MP and evaluate whether age has any impact on this association. Methods. A total of 951 subjects were included in this study. Complete clinical and laboratory data were collected. According to the characteristics of the most stenotic plaque, we divided them into 2 groups: calcified plaque (CP) and NCP/MP. Subjects with no plaque were classified as the control group (CR). Subjects with age≥60 years were defined as older adults, and those with age<60 years were classified as nonelderly people. Results. Patients with NCP/MP had significantly higher hsCRP level compared with subjects with CR or CP in older adults but not in nonelderly people. The proportion of NCP/MP was significantly increased from 27.0% in the hsCRP<1.25 mg/L group to 42.7% in the hsCRP>2.70 mg/L group in older adults. Multiple logistic regression analysis showed that hsCRP was an independent risk factor for the presence of NCP/MP (odds ratio OR=1.093, 95% CI 1.032–1.157, P=0.001) only in older adults. Conclusions. hsCRP is independently associated with the presence of NCP/MP in older adults but not in nonelderly people. These results suggest the potential significance of hsCRP-lowering regimens in older adults with NCP/MP.

Diagnosis of Anastomotic Leak

2021 ◽  
Vol 34 (06) ◽  
pp. 391-399
Author(s):  
Paul T. Hernandez ◽  
Raj M. Paspulati ◽  
Skandan Shanmugan
Keyword(s):  
Anastomotic Leak ◽  
Surgical Intervention ◽  
Laboratory Data ◽  
Water Soluble ◽  
Contrast Study ◽  
Anastomotic Leaks ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Water Soluble Contrast ◽  
The Impact

AbstractAnastomotic leaks after colorectal surgery is associated with increased morbidity and mortality. Understanding the impact of anastomotic leaks and their risk factors can help the surgeon avoid any modifiable pitfalls. The diagnosis of an anastomotic leak can be elusive but can be discerned by the patient's global clinical assessment, adjunctive laboratory data and radiological assessment. The use of inflammatory markers such as C-Reactive Protein and Procalcitonin have recently gained traction as harbingers for a leak. A CT scan and/or a water soluble contrast study can further elucidate the location and severity of a leak. Further intervention is then individualized on the spectrum of simple observation with resolution or surgical intervention.

Coagulation indicators and their association with apoptosis ,flammatory indicators and Sharp scores of rheumatoid arthritis

2020 ◽  
Author(s):  
Xin Wang ◽  
Jian Liu
Keyword(s):  
Rheumatoid Arthritis ◽  
Strong Correlation ◽  
Laboratory Data ◽  
Hypercoagulable State ◽  
C Reactive Protein ◽  
X Ray ◽  
Reactive Protein ◽  
Sharp Score ◽  
Abnormal Increase ◽  
The Relationship

Abstract Background Recent studies have shown that coagulations indicators hava a strong correlation with apoptosis ,flammatory indexes.In the present study, we measured coagulation indicators such PAF,PGI2 and TXB2 in patients with RA and investigated their association with apoptosis,flammatory indicators and Sharp scores of rheumatoid arthritis (RA). Methods A total of 90 patients diagnosed with rheumatoid arthritis were enrolled for comparisons. The clinical and laboratory data of patients were retrospectively reviewed. The X-ray findings of both hands were scored according to Sharp's criteria. In addition, the statistics of patients with apoptosis indicator,coagulation indicator and flammatory indicator. Explored the relationship between coagulation indiccators and the above indicators. Results In this study,there was a strong correlation between the abnormal increase of apoptosis parameters,immune inflammation indicators,Sharp Score and the increase of coagulation indicator in patients with rheumatoid arthritis, and the increase of Sharp Scores,Caspase-3,FasL indexes or the decrease of C-reactive protein (CRP)could be risk factors for the development of RA. The higher the coagulation indicator, the higher the Sharp score,and the high parameters of hypercoagulable state RA. Conclusions Higher coagulation indicators are associated with RA disease activity, as well as apoptosis ,flammatory indicators and decreased physical activity. Moreover, coagulation indicator are associated with Sharp scores.Coagulation indicator are important for the diagnosis of rheumatoid arthritis and are potential markers of activity and hypercoagulable state in RA patients.

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