scholarly journals Effect of physiotherapy on single breath count and breath holding time in COVID-19 patients

2021 ◽  
Vol 9 (10) ◽  
pp. 3062
Author(s):  
Sushama A. Bhandare ◽  
Sayali S. Rasal ◽  
Anil M. Sathe ◽  
Vaishnavi R. Nagpure ◽  
Urvi B. Parmar ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Treatment Session ◽  
Post Treatment ◽  
Mean Difference ◽  
Holding Time ◽  
Breath Holding ◽  
Care Hospital ◽  
Physiotherapy Treatment ◽  
Single Breath ◽  
Significant Difference

Background: The novel Coronavirus is known to primarily affect the respiratory system and physiotherapy treatment is integral to combat this infection. However, the assessment of pulmonary function poses a difficult challenge considering the risk of spread of infection and sanitisation of the devices used. Single breath count (SBC) and breath holding time (BHT) can be thus adopted as bedside assessment tests for pulmonary function following physiotherapy treatment.Method: In this a retrospective observational study of 51 COVID-19 patients, mean age 51.7±14.56 years, on room air, admitted in the step-down units of a tertiary care hospital. Patients received standard physiotherapy treatment, within safe hemodynamic limits. Pre and post treatment session SBC was recorded in 32 patients and BHT in 19 patients. Three reading were noted and the best of three readings were used for analysis.Results: The paired t test was used to analyse SBC and BHT. Mean pre and post SBC was 18.25±8.96 and 23.31±9.96 respectively with a mean difference of 5.06 and p<0.0001. Mean pre and post BHT were 19.37 and 23.05 seconds respectively with a mean difference of 3.68 and p<0.0001.  Statistically significant difference in the pre and post treatment session SBC and BHT was observed, indicating a positive effect of physiotherapy treatment on pulmonary function.Conclusion: Physiotherapy treatment shows significant improvement in the pulmonary function in COVID-19 patients. SBC and BHT tests can be used as assessment and prognostic tools for pulmonary function in COVID-19 patients.

“Alveolar plateau” of the single breath nitrogen elimination curve in normal subjects

1959 ◽  
Vol 14 (1) ◽  
pp. 105-108 ◽  
Author(s):  
Ingemar Kjellmer ◽  
Lars Sandqvist ◽  
Erik Berglund
Keyword(s):  
Flow Rate ◽  
Normal Subjects ◽  
Holding Time ◽  
Breath Holding ◽  
Flow Rates ◽  
Alveolar Plateau ◽  
Single Breath ◽  
The Difference ◽  
Nitrogen Elimination ◽  
Elimination Curve

The single breath N2 elimination test, as standardized by Comroe and Fowler, has been used in normal subjects. The N2 difference, i.e. the difference in N2 concentration between Ve = 1250 and Ve = 750 ml, showed a tendency to increase with increasing volumes of inspired O2 and with increasing inspiratory flow rates. It decreased with increasing breath-holding time and was not consistently influenced by expiratory flow rate. The findings are compared with those of Fowler and of Shephard on normal subjects; different results were obtained, largely depending on different analytical procedures. These factors must be considered when evaluating results in patients. Submitted on July 21, 1958

Single-breath breath-holding estimate of pulmonary blood flow in man: comparison with direct Fick cardiac output

1989 ◽  
Vol 76 (6) ◽  
pp. 673-676 ◽  
Author(s):  
A. H. Kendrick ◽  
A. Rozkovec ◽  
M. Papouchado ◽  
J. West ◽  
G. Laszlo
Keyword(s):  
Blood Flow ◽  
Cardiac Output ◽  
Pulmonary Blood Flow ◽  
Hold Time ◽  
Normal Subjects ◽  
Breath Holding ◽  
Breath Hold ◽  
Single Breath ◽  
Significant Difference ◽  
Cardiac Disorders

1. Resting pulmonary blood flow (Q.), using the uptake of the soluble inert gas Freon-22 and an indirect estimate of lung tissue volume, has been estimated during breath-holding (Q.c) and compared with direct Fick cardiac output (Q.f) in 16 patients with various cardiac disorders. 2. The effect of breath-hold time was investigated by comparing Q.c estimated using 6 and 10 s of breath-holding in 17 patients. Repeatability was assessed by duplicate measurements of Q.c in the patients and in six normal subjects. 3. Q.c tended to overestimate Q.f, the bias and error being 0.09 l/min and 0.59, respectively. The coefficient of repeatability for Q.c in the patients was 0.75 l/min and in the normal subjects was 0.66 1/min. For Q.f it was 0.72 l/min. There was no significant difference in Q.c measured at the two breath-hold times. 4. The technique is simple to perform, and provides a rapid estimate of Q., monitoring acute and chronic changes in cardiac output in normal subjects and patients with cardiac disease.

Pulmonary toxicity in patients receiving docetaxel chemotherapy

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e13532-e13532
Author(s):  
U. Kefeli ◽  
P. F. Yumuk ◽  
B. Ceyhan ◽  
F. Dane ◽  
B. Eroglu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pulmonary Function ◽  
Cumulative Dose ◽  
Pulmonary Toxicity ◽  
Pulmonary Function Tests ◽  
Post Treatment ◽  
Function Tests ◽  
Significant Difference ◽  
Docetaxel Treatment ◽  
Docetaxel Chemotherapy

e13532 Background: Docetaxel is used widely as monotherapy or in combination for the treatment of various types of cancers. Although rarely observed, pulmonary toxicity can be seen with docetaxel. This side effect had been reported mostly in non-small cell lung cancer patients receiving docetaxel. We aimed to investigate the pulmonary toxicity in patients receiving docetaxel chemotherapy other than lung cancer. Methods: 34 patients were investigated prospectively to demonstrate the pulmonary toxicity of docetaxel. Pulmonary function tests (PFTs) and high-resolution computed tomography (HRCT) scans were applied to all patients before chemotherapy and 14 - 21 days after completion of treatment. We used a HRCT scoring system that was based on the previous studies. All HRCT images were reviewed by two different observers. Results: We have seen no pulmonary symptoms that may reflect pulmonary toxicity in 34 patients. There were statistically significant differences between pre- and post-treatment values of FEV1 (L/sec) (p<0.05), FEV1/FVC (%) (p<0.05), FEF25–75 (L/sec) (p<0.01), FEF25–75 (%) (p<0,01), DLCO (mL/mmHg/min) (p<0.001), DLCO (%) (p<0.001), DLCO/VA (DLCO/L) (p<0.05), and DLCO/VA (%) (p<0.05). Also, there was a statistically significant difference between the pre- and post-treatment HRCT scores. The differences between pre- and post- treatment values of pulmonary function tests were not correlated with the number of docetaxel cycles and cumulative dose. There was a statistical relationship between number of docetaxel cycles (r =0.468, p<0.0001), docetaxel cumulative dose (r=0,596, p<0.0001) and HRCT scores after completion of docetaxel treatment. Conclusions: Although we have shown that docetaxel treatment causes a decline in PFTs and worsens HRCT scores, the symptoms of patients were not consistent with these differences. Therefore, it should be noted that the negative effects of docetaxel on PFTs and HRCT scores should be investigated by increasing the number of patients. No significant financial relationships to disclose.

scholarly journals EFFECTS OF BUTEYKO BREATHING TECHNIQUE AND CONVENTIONAL PHYSICAL THERAPY IN ADULT BRONCHIAL ASTHMA: A RANDOMIZED CONTROL TRAIL

2017 ◽  
Vol 6 (1) ◽  
pp. 36-44
Author(s):  
Qurat ul Ain Ausaf ◽  
Ghazala Noor Nizami ◽  
Amna Aamir Khan
Keyword(s):  
Physical Therapy ◽  
Bronchial Asthma ◽  
Tertiary Care ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Treatment Session ◽  
Care Hospital ◽  
Significant Difference ◽  
Related Quality ◽  
Randomized Control

OBJECTIVE To assess the effectiveness of Buteyko Breathing Technique (BBT) and Conventional Physical Therapy (Conventional PT) for improving pulmonary functions and Health Related Quality of Life (HRQoL) in the management of chronic bronchial asthma. STUDY DESIGN & SAMPLING TECHNIQUE It is a Randomized Control Trial. Patients were selected through Simple Random Sampling. STUDY SETTING & PARTICIPANTS 24 patients diagnosed as chronic bronchial asthma were recruited from the outpatient department, pulmonary clinics of tertiary care hospital. INTERVENTION Subjects were randomly assigned into two groups, BBT (n=12) and conventional PT (n=12). FEV1, FVC and FEV1/FVC ratio were measured at the start and end of the treatment through MIR Spirolab-III. HRQoL was also measured using St George Respiratory Questionnaire (SGRQ) at start and end of treatment session. RESULTS No statistically significant changes were observed in FVC, FEV1 and FEV1/FVC ratio in BBT as well as in Conventional PT whereas significant changes in HRQoL through SGRQ is revealed in BBT (p <0.05). CONCLUSION BBT is found to be more effective in assessing HRQoL through SGRQ, whereas a larger sample size is required in patients with chronic bronchial asthma to evaluate the effectiveness of BBT as no significant difference was shown in the study.

scholarly journals Efficacy of Topiramate as Prophylactic Treatment of Severe Migraine in Children attending OPD of a Tertiary Care Hospital in Bangladesh- a Randomized Control Trial

2021 ◽  
Vol 44 (3) ◽  
pp. 153-156
Author(s):  
Banita Mistry ◽  
Shameem Ara Begum ◽  
Narayan Saha ◽  
Shyamal Sarker ◽  
Mahua Chandra ◽  
...  
Keyword(s):  
Treatment Group ◽  
Prophylactic Treatment ◽  
Tertiary Care ◽  
Post Treatment ◽  
Control Group ◽  
Care Hospital ◽  
Treatment Frequency ◽  
Significant Difference ◽  
Severe Intensity ◽  
Severe Migraine

Background: Migraine is the most common cause of severe recurrent headache in children. Flunarizine (FNZ) is safe and effective drug for prevention of migraine in children. Topiramate (TPM) is also successful as a preventive drug for migraine in children on randomized, double-blind, placebo-controlled trials. Objective: This study was done to observe the efficacy of Topiramate and also perform a comparison TPM and FNZ in patients with migraine of severe intensity in our situation. Materials & Methods: This was a randomized controlled trial done from January to July, 2018. This study was carried out in the OPD of Paediatric Neurology department, National Institute of Neurosciences, (NINS) Dhaka. Forty Children, 5-15 years old diagnosed as migraine with/without aura with severe intensity were randomized either as in study group (TPM treatment group) and control group (FNZ treatment group). Primary end point of the study was to find out the efficacy and safety of both TPM and FNZ after 4 months of treatment. Result: Post-treatment frequency of headache/month was significantly decreased in both groups (within group, p <0.001). There was no significant difference considering pre and post-treatment frequency of headache/month between two treatment groups. (pre-treatment p- 0.333 and post-treatment p- 0.401). Adverse events were not significantly different between the groups p<0.387. Conclusion: Topiramate is equally efficacious as Flunarizine in prophylactic treatment of severe migraine in children. Bangladesh J Child Health 2020; VOL 44 (3) :153-156

scholarly journals Effect of Asanas on Selected Physical and Physiological Variables among Young Adult Women

2018 ◽  
Vol 7 (2) ◽  
pp. 107-109
Author(s):  
K. Johnbosco
Keyword(s):  
Young Adult ◽  
Pulse Rate ◽  
Holding Time ◽  
Breath Holding ◽  
Control Group ◽  
Adult Women ◽  
Young Adult Women ◽  
Physiological Variable ◽  
Physiological Variables ◽  
Significant Difference

Today the awareness of maintaining good health has been on the high and people attend to physical exercise sessions even without knowing the actual physiological and spiritual values of yogic practices. To achieve this purpose, twenty four female students who are studying in Bharathidasan University affiliated college, Tiruchirappalli were selected as subjects at random and their age ranged between from 20-25 years Physical and physiological variable will be selected by reviewing and studying related literature in detail following criterion variables are selected for this. Physical variable flexibility and strength endurance physiological variable resting pulse rate breath holding time the pre and posttest control group design will be used for this study. To find out the significant difference on adjusted posttest among the groups, analysis of co-variance (ANCOVA) would use. There was significant improvement on flexibility, strength endurance physiological variable resting pulse rate breath holding time due to the effect of asanas training among young adult women.

scholarly journals Effects of Static Apnea Training on Pulmonary Function, Blood Lactate Response and Exercise Performance of Elite Swimmers

2020 ◽  
Vol 29 (3) ◽  
pp. 272-280
Author(s):  
Heejeong Son ◽  
Yunah Jeon ◽  
Hyosik Kim
Keyword(s):  
Pulmonary Function ◽  
Blood Lactate ◽  
Swimming Performance ◽  
Pulmonary Function Tests ◽  
Breath Holding ◽  
Control Group ◽  
Significant Difference ◽  
Elite Swimmers ◽  
Lactate Levels ◽  
Blood Lactate Levels

PURPOSE: The purpose of this study was to investigate the effects of training on improvement in pulmonary function and swimming performance by implementing static apnea training for 4 weeks in elite male swimmers.METHODS: Twenty elite swimmers were divided into two groups, the apnea training group (Apnea, n=11) and the control group (control, n=9). Each swimmer received identical swimming and ground training for 4 weeks. The apnea group performed 10 sets of breathholding a day additionally. In all participants, the pulmonary function tests [forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV1)] were evaluated. The blood lactate level was also measured after each swimmer completed swimming 5 laps.RESULTS: After 4 weeks of static apnea training, the FVC of the apnea group significantly increased (p=.008), whereas the FEV1/FVC ratio did not change. Breath-holding time increased significantly after apnea training (p=.001). There were no significant differences between the groups in the 50-m time trial records. However, the apnea group show a significant difference at the 4th (p=.013) and 5th trial (p=.023). The blood lactate levels after the 50-m trial was not significantly different between the groups, but the levels in the apnea group showed a significant increase in the results of the 2nd trial compared to those before apnea training (p=.008).CONCLUSIONS: The results of our study reveal that static apnea training improves pulmonary function, in contrast to a few time trials that show varying differences in swimming records and blood lactate levels. These results warrant a review of the training protocol to evaluate the effect on performance. In conclusion, static apnea training is a potential exercise that can improve performance in competitive sports.

scholarly journals Functional Status of Acute Covid-19 Patients Receiving Physiotherapy, At Discharge: A Case Series

2021 ◽  
Vol 9 (3) ◽  
pp. 3854-3861
Author(s):  
Shivam N. Chopra ◽  
◽  
Jyotsna A. Thosar ◽  
Jaimala V. Shetye ◽  
◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Functional Status ◽  
Case Series ◽  
The Body ◽  
Breath Holding ◽  
Breath Hold ◽  
Single Breath ◽  
Single Breath Hold ◽  
Sit To Stand ◽  
6 Minute Walk Test

COVID-19 affection is known to show multi-system involvement. As impairments are expected to be seen in various systems of the body, outcomes related to the function of different systems should be considered while evaluating a patient. This case series of 5 patients brings out the functional status of acute covid-19 patients admitted to the hospital. The evaluation involves outcomes related to Musculo-skeletal (30 second sit to stand test) pulmonary function (single breath hold & breath holding time) and functional capacity (6-minute walk test), which were practical in COVID-19 scenario, in view of maintaining restricted contact with the patient. The evaluation is also done at the time of discharge from the hospital to evaluate the need for post-acute-covid rehabilitation. KEY WORDS: COVID-19, impairments, Musculo-skeletal, pulmonary function.

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