scholarly journals Counselling-in-continuum-modern solution to ‘Google’ patients?

2021 ◽  
Vol 8 (8) ◽  
pp. 2515
Author(s):  
Ina Bahl ◽  
Sanat Kumar Khanna
Keyword(s):  
Scientific Evidence ◽  
Treatment Options ◽  
Effective Communication ◽  
Disease Treatment ◽  
Patient Counselling ◽  
Sound Communication ◽  
Management Plans ◽  
Legal Document ◽  
Pros And Cons ◽  
Modern Solution

Aim of the study was to highlight the benefits, barriers and methodology pertaining to effective patient counselling. The modern-day patient is well informed and well aware of patient rights. The need of the hour is to implement management plans jointly agreed upon based on both scientific evidence and patient preference by proper patient counselling. The process of counselling represents a well-founded intervention made of a quality interaction between the counsellor and the patient. Effective communication is advantageous for both healthcare professionals in the form of a comprehensive medico legal document, as well as for the patient as it tends to allay fear of treatment, dissipate misconceptions garnered from half-baked knowledge off the internet, cementing a bond of trust between the two. Counselling forms should carry information pertaining to the details regarding the patient’s disease, treatment options, pros and cons with aids in the form of pictures, models and videos. Ample time should be spent on the patient’s doubts, without the use of medical jargons. Barriers to effective communication include physical, psychological, administrative or time conflicts. Upliftment from the quick sands of barriers to patient communication requires the introduction of a curriculum laying emphasis on sound communication skills right from the undergraduate stage. Furthermore, internet can be used to aid counselling in the form of legit informative portals wherein patients are able to gather correct information about their disease and prognosis as is the case with online healthcare communities.

Vitamin C as an Anticancer Agent: Regulation of Signaling Pathways

2020 ◽  
Vol 20 (21) ◽  
pp. 1868-1875
Author(s):  
Ghazala Butt ◽  
Ammad A. Farooqi ◽  
Aima Adylova ◽  
Rukset Attar ◽  
Seher Yilmaz ◽  
...  
Keyword(s):  
Vitamin C ◽  
Cancer Cells ◽  
Signaling Pathways ◽  
Scientific Evidence ◽  
Treatment Options ◽  
Published Data ◽  
New Era ◽  
Molecular Oncology ◽  
Anticancer Effects ◽  
Oncogenic Pathways

Treatment options for effective treatment of cancer with minimum off-target effects and maximum clinical outcomes have remained overarching goals in the clinical oncology. Vitamin C has remained in the shadows of controversy since the past few decades; burgeoning evidence has started to shed light on wide-ranging anticancer effects exerted by Vitamin C to induce apoptosis in drug-resistant cancer cells, inhibit uncontrolled proliferation of the cancer cells and metastatic spread. Landmark achievements in molecular oncology have ushered in a new era, and researchers have focused on the identification of oncogenic pathways regulated by Vitamin C in different cancers. However, there are visible knowledge gaps in our understanding related to the ability of Vitamin C to modulate a myriad of transduction cascades. There are scattered pieces of scientific evidence about promising potential of Vitamin C to regulate JAK-STAT, TGF/SMAD, TRAIL and microRNAs in different cancers. However, published data is insufficient and needs to be investigated comprehensively to enable basic and clinical researchers to reap full benefits and promote result-oriented transition of Vitamin C into various phases of clinical trials. In this review, we will emphasize on available evidence related to the regulation of oncogenic cell signaling pathways by Vitamin C in different cancers. We will also highlight the conceptual gaps, which need detailed and cutting-edge research.

Alternative medicine as a treatment options for COVID-19

2021 ◽  
Vol 07 ◽  
Author(s):  
Mahfuza Marzan ◽  
Md. Shahedur Rahman ◽  
Md. Abu Hena Mostofa Jamal ◽  
Mohammad Hossain Shariare ◽  
Md. Anowar Khasru Parvez
Keyword(s):  
Health Care ◽  
Vitamin D ◽  
Distress Syndrome ◽  
Scientific Evidence ◽  
Treatment Options ◽  
Viral Disease ◽  
Global Pandemic ◽  
Medicinal Properties ◽  
Mode Of Transmission ◽  
High Infectivity

: COVID-19, a viral disease caused by SARS-CoV-2 is the reason of a global pandemic since the starting of the year 2020. The characteristic of the disease varies from mild common cold like symptoms to acute respiratory distress syndrome and multi-organ failure leading to death. World has already observed 213,453 deaths from this disease while 3,095,839 have been infected in 210 countries in total till 28 April, 2020. This disease has a devastating impact over the health care system because of its high infectivity, easy mode of transmission, lack of proper medicine and vaccine and deficiency of enough supportive healthcare arrangement. On verge of this situation scientists are searching the treatment options. However, nature has provided us with enormous herbs which have disease preventive as well as have medicinal properties. In this article we have reviewed several of these plants (ginger, clove, tea, black seed, tulsi, neem) and some vitamins (vitamin C and vitamin D) and zinc which have antiviral, anti-inflammatory, antioxidant, anti-asthmatic properties with scientific evidence. The intake of these products regularly to keep the immune system active, to experience its positive aspects might be supportive to prevent infection with the new coronavirus or to treat COVID-19.

scholarly journals Patient profiles as an aim to optimize selection in the second line setting: the role of aflibercept

2021 ◽  
Author(s):  
B. González Astorga ◽  
F. Salvà Ballabrera ◽  
E. Aranda Aguilar ◽  
E. Élez Fernández ◽  
P. García-Alfonso ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Therapeutic Option ◽  
Scientific Evidence ◽  
Treatment Options ◽  
Line Treatment ◽  
Second Line ◽  
First Line ◽  
Effective Therapeutic Option ◽  
Line Setting ◽  
First Line Treatment

AbstractColorectal cancer is the second leading cause of cancer-related death worldwide. For metastatic colorectal cancer (mCRC) patients, it is recommended, as first-line treatment, chemotherapy (CT) based on doublet cytotoxic combinations of fluorouracil, leucovorin, and irinotecan (FOLFIRI) and fluorouracil, leucovorin, and oxaliplatin (FOLFOX). In addition to CT, biological (targeted agents) are indicated in the first-line treatment, unless contraindicated. In this context, most of mCRC patients are likely to progress and to change from first line to second line treatment when they develop resistance to first-line treatment options. It is in this second line setting where Aflibercept offers an alternative and effective therapeutic option, thought its specific mechanism of action for different patient’s profile: RAS mutant, RAS wild-type (wt), BRAF mutant, potentially resectable and elderly patients. In this paper, a panel of experienced oncologists specialized in the management of mCRC experts have reviewed and selected scientific evidence focused on Aflibercept as an alternative treatment.

scholarly journals Symposium report: breast cancer in India—trends, environmental exposures and clinical implications

2021 ◽  
Vol 32 (6) ◽  
pp. 567-575
Author(s):  
Jasmine A. McDonald ◽  
Roshni Rao ◽  
Marley Gibbons ◽  
Rajiv Janardhanan ◽  
Surinder Jaswal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Scientific Evidence ◽  
Treatment Options ◽  
Environmental Exposures ◽  
Population Based ◽  
Clinical Implications ◽  
Think Tank ◽  
Case Control Studies ◽  
Short Term

Abstract Purpose Incidence of breast cancer (BC), particularly in young women, are rising in India. Without population-based mammography screening, rising rates cannot be attributed to screening. Investigations are needed to understand the potential drivers of this trend. Methods An international team of experts convened to discuss the trends, environmental exposures, and clinical implications associated with BC in India and outlined recommendations for its management. Results Panels were structured across three major BC themes (n = 10 presentations). The symposium concluded with a semi-structured Think Tank designed to elicit short-term and long-term goals that could address the challenges of BC in India. Conclusion There was consensus that the prevalence of late-stage BC and the high BC mortality rates are associated with the practice of detection, which is primarily through clinical and self-breast exams, as opposed to mammography. Triple-Negative BC (TNBC) was extensively discussed, including TNBC etiology and potential risk factors, the limited treatment options, and if reported TNBC rates are supported by rigorous scientific evidence. The Think Tank session yielded long-term and short-term goals to further BC reduction in India and included more regional etiological studies on environmental exposures using existing India-based cohorts and case–control studies, standardization for molecular subtyping of BC cases, and improving the public’s awareness of breast health.

scholarly journals The challenge of choosing in cardiovascular risk management

2021 ◽  
Author(s):  
R. M. Hoogeveen ◽  
N. M. J. Hanssen ◽  
J. R. Brouwer ◽  
A. Mosterd ◽  
C. J. Tack ◽  
...  
Keyword(s):  
Risk Management ◽  
Treatment Options ◽  
Preventive Therapy ◽  
Lifestyle Modifications ◽  
Cvd Risk ◽  
Cardiovascular Risk Management ◽  
Therapeutic Decisions ◽  
Preventive Medication ◽  
Pros And Cons ◽  
The Absolute

AbstractCardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide. For many years guidelines have listed optimal preventive therapy. More recently, novel therapeutic options have broadened the options for state-of-the-art CV risk management (CVRM). In the majority of patients with CVD, risk lowering can be achieved by utilising standard preventive medication combined with lifestyle modifications. In a minority of patients, add-on therapies should be considered to further reduce the large residual CV risk. However, the choice of which drug combination to prescribe and in which patients has become increasingly complicated, and is dependent on both the absolute CV risk and the reason for the high risk. In this review, we discuss therapeutic decisions in CVRM, focusing on (1) the absolute CV risk of the patient and (2) the pros and cons of novel treatment options.

Preferences of Nephrologists among End-Stage Renal Disease Treatment Options

1985 ◽  
Vol 5 (6) ◽  
pp. 470-475 ◽  
Author(s):  
Cindy Dunham ◽  
William D. Mattern ◽  
William C. McGaghie
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Disease Treatment ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Reasons for inpatients not to seek clarity at Dr George Mukhari Academic Hospital, Pretoria

2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Langalibalele H. Mabuza ◽  
Olufemi B. Omole ◽  
Indiran Govender ◽  
John V. Ndimande
Keyword(s):  
South Africa ◽  
Prior Knowledge ◽  
Effective Communication ◽  
Self Esteem ◽  
Tertiary Hospital ◽  
Bad News ◽  
Academic Hospital ◽  
Management Plans ◽  
Clinical Conditions

Background: Healthcare practitioners should provide patients with information regarding their clinical conditions. Patients should also feel free to seek clarity on information provided. However, not all patients seek this clarity.Objectives: To explore the reasons inpatients gave for not seeking clarity on information that was received but not understood.Methods: This was a qualitative arm of a larger study, titled ‘Are inpatients aware of the admission reasons and management plans of their clinical conditions? A survey at a tertiary hospital in South Africa’, conducted in 2010. Of the 264 inpatients who participated in the larger study, we extracted the unstructured responses from those participants (n = 152) who had indicated in the questionnaire that there was information they had not understood during their encounter with healthcare practitioners, but that they had nonetheless not sought clarity.Data were analysed thematically.Results: Themes that emerged were that inpatients did not ask for clarity as they perceived healthcare practitioners to be ‘too busy’, aloof, non-communicators and sometimes uncertain about patients’ conditions. Some inpatients had unquestioning trust in healthcare practitioners,whilst others had experiences of bad treatment. Inpatients had poor self-esteem, incapacitating clinical conditions, fear of bad news and prior knowledge of their clinical conditions. Some inpatients stated that they had no reason for not seeking clarity.Conclusion: The reasons for not seeking clarity were based on patients’ experiences with the healthcare practitioners and their perceptions of the latter and of themselves. A programme should be developed in order to educate inpatients on effective communication with their healthcare practitioners.

scholarly journals MODERN REVIEW OF ANATOMO-MORPHOLOGICAL FEATURES AND POSSIBILITIES OF SURGICAL CORRECTION OF VARICOCELE IN CHILDREN

2018 ◽  
Vol 22 (5) ◽  
pp. 263-268
Author(s):  
R. S. Zadykian ◽  
Sergey N. Zorkin ◽  
S. S. Zadykian
Keyword(s):  
Surgical Intervention ◽  
Treatment Options ◽  
Morphological Features ◽  
Surgical Correction ◽  
Proper Treatment ◽  
Anatomical Features ◽  
Pathophysiological Mechanisms ◽  
Pros And Cons

Varicocele is a frequent pathology of the testicles, detected during preventive examinations and subsequently often associated with infertility. The most common is the left varicocele. This review presents anatomical features and basic pathophysiological mechanisms promoting the development of varicocele in childhood. For proper treatment of this pathology, a careful approach to the examination and determination of the indications and tactics of the planned surgical intervention is necessary. There is a lot of disagreement about the need, time and technique of the intervention. The practitioner should balance the pros and cons of timing and treatment options.

scholarly journals Corporoplasty in Peyronie’s Disease: a Literature Review

2021 ◽  
Vol 11 (3) ◽  
pp. 209-219
Author(s):  
V. N. Pavlov ◽  
A. A. Bakirov ◽  
R. A. Kazikhinurov ◽  
A. A. Kazikhinurov ◽  
M. A. Agaverdiev ◽  
...  
Keyword(s):  
Treatment Options ◽  
Penile Prosthesis ◽  
Peyronie’S Disease ◽  
Usual Practice ◽  
Current Trends ◽  
Penile Deviation ◽  
Pros And Cons ◽  
Peyronie's Disease ◽  
Correction Surgery ◽  
Review Current

Corporoplasty is urological correction surgery for penile deviation that causes copulatory dysfunction or aesthetic discomfort. Penile deviation can be congenital or acquired (Peyronie’s disease, penile fracture). Congenital penile deviation is relatively rare and manifests in the curvature of erect penis ventrally and/or laterally, in most cases. According to many studies, patients with curvatures of 30° or more eventually seek surgical treatment. Congenital curvature may be mistaken for Peyronie’s disease for similar manifestations that, however, differ in aetiology and pathophysiology. Excisional, incisional corporoplasty or plication are commonly engaged to treat congenital curvatures, in various techniques and modifications. Augmentation transplantation (grafting) and penile prosthesis implantation with variant deviation treatment options are the usual practice in Peyronie’s disease. Unequivocal judgment of pros and cons in any particular technique is nevertheless implausible to make. This article aims to review current trends, protocols and their relative advantages in corporoplasty.

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