scholarly journals Cord blood albumin as a predictor of neonatal hyperbilirubinemia in healthy neonates

2017 ◽  
Vol 4 (2) ◽  
pp. 503 ◽  
Author(s):  
Gaurav Aiyappa K. C. ◽  
Ashvij Shriyan ◽  
Bharath Raj
Keyword(s):  
At Risk ◽  
Risk Factor ◽  
Prospective Study ◽  
Exchange Transfusion ◽  
Neonatal Jaundice ◽  
Neonatal Hyperbilirubinemia ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

Background: Neonatal jaundice or icterus neonatrum has been observed in newborn babies for many centuries. The objective of this study was to determine the correlation between cord albumin levels and development of hyperbilirubinemia in term healthy neonates.Methods: A prospective study was conducted on 165 term healthy neonates. Gender, gestational age, anthropometric measurements were taken into consideration. It was ascertained that there was no other risk factor for hyperbilirubinemia amongst the neonates. The neonates were divided into two groups A and B based on the cord albumin levels of <2.8 gm/dl and >2.8 gm/dl.Results: Of the 165 babies included in the study, 126 babies were under Group 1 and 39 under Group 2. 44 babies (34%) in group 1 and 28 babies (71.7%) in group 2 (p<0.0005) developed clinical icterus of which 16 in group 1 and 19 in group 2 required phototherapy (p<0.05). 1 baby in group required exchange transfusion. The sensitivity and specificity of cord albumin in detecting neonatal hyperbilirubinemia in this study was determined to be 71.8% and 65.1% respectively.Conclusions: Cord albumin levels help to determine and predict the possibility of hyperbilirubinemia among neonates. Hence this can help to identify the at-risk neonates. So, routine determination of cord albumin can be advocated to keep a track on at risk neonates.

scholarly journals To study the effectiveness of cord blood Albumin as a predictor of neonatal jaundice

2017 ◽  
Vol 4 (2) ◽  
pp. 645
Author(s):  
Nithu A. George ◽  
Shyam Sudhir M. K.
Keyword(s):  
Cord Blood ◽  
Neonatal Jaundice ◽  
Mode Of Delivery ◽  
The Body ◽  
Neonatal Hyperbilirubinemia ◽  
Healthy Infants ◽  
Group 3 ◽  
Blood Albumin ◽  
Group 2 ◽  
Group 1

Background: Neonatal hyperbilirubinemia is one of the commonest problems in newborn. It can be due to different etiologies. Most often it is physiological jaundice. The main reasons for physiological jaundice is that in an infant the liver is not mature enough to handle the freely circulating bilirubin due to higher volume of short life erythrocytes in the circulation and low level of albumin. Early detection of neonatal jaundice is essential to prevent developing kernicterus as well as discharge the babies early. Albumin is synthesized by liver and helps in the transport of unconjugated bilirubin by binding to bilirubin it and thus making it nontoxic to the body. Low levels of albumin make bilirubin free and toxic to the body. Hence, this study was done to evaluate effectiveness of cord blood albumin as a predictor of neonatal Hyperbilirubinemia.Methods: 50 term healthy newborns were included in the study with the term babies of both genders from any mode of delivery, birth weight >2.5 kg, APGAR score more than 7 at 1st and 5th minutes of life and without Rh incapability. Cord blood albumin levels were measured. Blood test for bilirubin was done when required and baby was managed accordingly.Results: Out of the total 50 neonates enrolled, 7 belonged to group 1 (albumin <2.8 g/dl), 34 to group 2 (2.8-3.3 g/dl), and 9 to group 3 (>3.3 g/dl). Out of the total 7 neonates in group 1, 6 (85.71%) was icteric at 24-48 hours and 1 (14.29%) was icteric at >72 hours. All the 7 neonates developed Hyperbilirubinemia requiring phototherapy. 3 (42.86%) out the 7-neonate required phototherapy for more than 24 hours. Out of the total 34 neonates in group 2, 20 (58.82%) was icteric at >72 hours, 12 (35.29%) at 48-72 hours and 2 (5.88%) at 24-48 hours. Only 12 (35.29%) neonates had Hyperbilirubinemia requiring phototherapy. Out of the total 9 neonates in group 3, 1 was icteric at 48 - 72 hours and 8 was icteric at >72 hours. But only 2 had Hyperbilirubinemia requiring phototherapy.Conclusions: Cord blood albumin is an effective way to predict neonatal Hyperbilirubinemia in term healthy infants.

Genital Findings in Sexually Abused, Symptomatic and Asymptomatic, Girls

PEDIATRICS ◽  
1987 ◽  
Vol 79 (5) ◽  
pp. 778-785
Author(s):  
S. Jean Emans ◽  
Elizabeth R. Woods ◽  
Nancy T. Flagg ◽  
Amanda Freeman
Keyword(s):  
Prospective Study ◽  
Sexually Abused ◽  
Asymptomatic Children ◽  
Group 3 ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1 ◽  
Sexually Abused Girls

Although evaluation of the vulva of sexually abused girls using magnification with a colposcope or pediatric otoscope has become increasingly popular, the incidence of various genital findings in sexually abused and asymptomatic children has not been reported. A prospective study was carried out in which 20 genital findings from three groups of girls (mean age 4.8 ± 2.6 years) were analyzed. The three groups were (1) sexually abused girls (n = 119), (2) normal girls with no genital complaints (n = 127), and (3) girls with other genital complaints (n = 59). Group 1 was more likely than group 2 to have scars on the hymen or posterior forchette (9% v 1%, P = .002), increased friability of the posterior forchette (10% v 1%, P = .001), attenuated hymen (18% v 4%, P = .0003), and synechiae from the hymenal ring to the vagina (8% v 0%, P = .0009). Groups 1 and 3 were remarkably similar with the exception of erythema which was more common in group 3 (34% v 68%, P = .0001). Hymenal diameter was slightly greater in group 1 than 2 but not 3. Although genital findings distinguish some sexually abused girls from asymptomatic girls, many findings also occur in girls with other genital complaints, which suggests that many of these girls have also been molested or that vulvar inflammation may lead to some of these findings.

scholarly journals Daflon use for reducing post-tonsillectomy pain and hemorrhage: a prospective study

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Ahmed Shehata El Sayed Saleh ◽  
Hossam Mohamed Kamal Rabie
Keyword(s):  
Prospective Study ◽  
Pain Control ◽  
Safe Procedure ◽  
Bipolar Diathermy ◽  
Secondary Hemorrhage ◽  
Pain Duration ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

Abstract Background Tonsillectomy usually was a safe procedure; in adults, the risk of agonizing pain and secondary hemorrhage could be serious. We introduced Daflon as a safe and effective complementary medication in reducing these risks. This prospective study was designed to evaluate the effect of using (Daflon oral medication) on post-tonsillectomy pain and hemorrhage rates. This study was conducted on 60 patients of both sexes, above 21 years, and underwent tonsillectomy using bipolar diathermy. Patients were randomly distributed between 2 groups; each group has 30 patients and with the same post-operative protocol; in group 2, an addition of Daflon 500 mg tablet twice daily for 14 days post-operatively was given. Results In group 2, agonizing pain start day, pain duration, analgesia duration, and need for another type, all were significantly different from group 1, starting day in group 1 (4.3 ± 4.0) and (7.2 ± 1.3) in group 2, pain duration in group 1 (7.3 ± 1.5) and (4.2 ± 1.4) in group 2 and need for more analgesia 80% in group 1 and 50% in group 2. Post-operative hemorrhage was 4 cases (13.3%) in group 1, and 2 cases (7%) in group 2, also severity of post-operative bleeding were less in group 2. Healing membrane detaching time was (12.2 ± 2.2) in group 1 and (9.1 ± 1.9) in group 2. Conclusion The use of Daflon 500 mg tablet after bipolar tonsillectomy added to effectiveness of pain control also could help in reducing bleeding rates and its severity. Overall, its use enhances recovery and improves quality of life.

Thermal ablation of saphenous veins is feasible and safe in patients older than 75 years: A prospective study (EVTA study)

2014 ◽  
Vol 30 (8) ◽  
pp. 525-532 ◽  
Author(s):  
C Hamel-Desnos ◽  
P Desnos ◽  
F-A Allaert ◽  
P Kern ◽  
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
Thermal Ablation ◽  
Cardiac Insufficiency ◽  
Control Group ◽  
Saphenous Veins ◽  
Group 2 ◽  
Multicenter Prospective Study ◽  
A Prospective Study ◽  
Group 1

Objectives To investigate the tolerance and safety of thermal ablation (TA), consisting of radiofrequency or endovenous laser (EVLA) of saphenous veins (SV) in elderly (group 1 ≥75 years), compared with a control group (group 2 <75 years). Method An Observational multicenter-prospective study was conducted, under the aegis of the French and Swiss Societies of Phlebology (18 centers). Ninety patients were included in group 1, 617 in group 2 (mean age 80 years and 53 years; 69% women in both groups), representing 863 SV. Mean trunk diameters were similar in both groups (small SV: 6 mm; great SV: 7 mm). In group 1, comorbidities were more frequent, particularly cardiac insufficiency, diabetes, history of thrombosis, and CEAP clinical class was significantly higher. Results EVLA was used in 86% of cases. Settings used were similar in both groups for each technique. Only 6% of TA was performed in an operating room for group 1 (14% group 2). Tumescent local anaesthesia (TLA) alone was used in 91% of cases in group 1 (85% group 2). The mean pain score was only 1.6 for the procedure itself (VASP 0–10; 10 max.) and 1.4 for the 10 days following the procedure. Side effects were few, but rate of paraesthesia was higher when general anaesthesia was used (11.8%) compared with TLA alone (2.2%). At three months, 100% of SV was occluded in group 1 (99.5% group 2), with high satisfaction score (9.3/10). Conclusion TA is safe and effective in elderly; it should be performed strictly under TLA to minimize side effects.

scholarly journals The level of satisfaction with their work and degree of burnout among anesthesiologists and emergency physicians working in the red zone of a COVID hospital

2021 ◽  
Vol 18 (2) ◽  
pp. 17-22
Author(s):  
А. V. Malyarchikov ◽  
K. G. Shapovalov
Keyword(s):  
Intensive Care ◽  
Prospective Study ◽  
Intensive Care Units ◽  
Working Conditions ◽  
Emergency Physicians ◽  
Level Of Satisfaction ◽  
High Satisfaction ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

The objective: To determine the level of satisfaction with their work and degree of burnout among anesthesiologists and emergency physicians working in the red zone of a COVID-19 hospital.Subjects and methods. A prospective study was conducted as an anonymous survey of physicians performing their duties in intensive care units of the red zone. 65 specialists were interviewed: Group 1 (52.3%) – trainee physicians, Group 2 (47.7%) – anesthesiologists and emergency physicians.Results. The majority of respondents in both groups noted relatively high satisfaction with their current work. At the same time, the majority of respondents (70.9%) in the group of anesthesiologists and emergency physicians would prefer the previous working conditions to current ones. Also, it was noted that both groups were highly emotionally exhausted.

Combined use of CO2 laser and tissue glue versus conventional surgical techniques for circumcision – A prospective study

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Akkrapol Mungnirandr ◽  
Suwanna Wiriyakamolphan ◽  
Ravit Ruangtrakool ◽  
Monawat Ngerncham ◽  
Sureerat Tumrongsombutsakul ◽  
...  
Keyword(s):  
Prospective Study ◽  
Co2 Laser ◽  
Surgical Techniques ◽  
Operation Time ◽  
Chromic Catgut ◽  
Tissue Glue ◽  
Combined Use ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

AbstractUse of a COThirty boys were divided into two groups. Group 1 (n=17) underwent circumcision using a scalpel with approximation of the wound edges using chromic catgut sutures. Group 2 (n=13) underwent circumcision using a COGroup 1 (scalpel+sutures) had a significantly longer operation time (The combined use of a CO

scholarly journals A Prospective Study to Evaluate the efficacy of Isopropyl Alcohol Irrigations to Prevent Cerumen Impaction

2012 ◽  
Vol 91 (3) ◽  
pp. E25-E28 ◽  
Author(s):  
Herbert Silverstein ◽  
Benjamin J. Wycherly ◽  
Yadiel Alameda ◽  
Mark J. Van Ess
Keyword(s):  
Prospective Study ◽  
Crossover Study ◽  
Isopropyl Alcohol ◽  
Initial Evaluation ◽  
Safety And Efficacy ◽  
Significant Difference ◽  
The Mean ◽  
Group 2 ◽  
A Prospective Study ◽  
Group 1

We conducted a prospective crossover study to assess the safety and efficacy of 70 % isopropyl alcohol delivered from a squeezable bottle with a specially designed tip as a weekly irrigant to reduce cerumen accumulation. Twenty patients were divided into 2 groups of 10 (20 ears in each group). The patients in group 1 instilled 70% isopropyl alcohol once a week for 2 months; this was followed by 2 months of no ear cleaning. The patients in group 2 performed the opposite routine. At each visit (0, 2, and 4 mo), cerumen accumulation was graded on a scale of 0 to 4, indicating 0, 25, 50, 75, and 100% occlusion, respectively. After the accumulation was graded, a cerumenectomy was performed. At the initial evaluation, the mean occlusion scores were 3.1 for group 1 and 3.3 for group 2—not a statistically significant difference. After the first 2 months of the study, there was a significant difference in occlusion scores between groups 1 and 2 (0.75 and 1.55, respectively; p (p = 0.38). At study's end, there were also significant differences within each group between occlusion scores obtained during the treatment and nontreatment periods (group 1: p 0.02; group 2: p.

scholarly journals Impact of Sport Activity and Physical Exercise on Obstetrical and Perineal Outcomes at Delivery: A Prospective Study

2019 ◽  
Vol 36 (S 02) ◽  
pp. S83-S90
Author(s):  
Stefano Uccella ◽  
Paolo Manzoni ◽  
Nicola Marconi ◽  
Carlotta Toscani ◽  
Sara Biasoli ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Exercise ◽  
Prospective Study ◽  
Sport Activity ◽  
Demographic Characteristics ◽  
Group 3 ◽  
Group 2 ◽  
A Prospective Study ◽  
Different Levels ◽  
Group 1

Objective This study was aimed to investigate the effects of physical activity on perineal outcomes at delivery according to the different levels and types of maternal physical activity before and during pregnancy. Study Design We prospectively evaluated the obstetrical and perineal outcomes of all consecutive women who delivered at the Del Ponte Hospital, in the period between July 2014 and September 2014. Women were divided into three groups according to the features of physical activity performed before pregnancy: group 1: “very sporty women,” group 2: “moderately sporty women,” and group 3: “inactive women.” A subanalysis of our data was performed based on the specific type of sport activity, on the degree of involvement of perineal muscles during physical activity, and on the continuation/discontinuation of this activity during pregnancy. Results A total of 135, 84, and 85 women were included in group 1, group 2, and group 3, respectively. The demographic characteristics were comparable among all the groups. Sport activity during pregnancy was more frequent in groups 1 and 2 (59.3 and 53.6%, respectively, vs. 29.4% in group 3; p = 0.003). No differences among groups were detected in terms of perineal outcomes. A lower rate of episiotomy/lacerations ≥ 2nd degree was found among women who practiced sports that specifically involved the perineal muscles and who continued this practice during pregnancy. Conclusion Perineal outcomes are not influenced by the intensity of sport activity performed before/during pregnancy. Continuous sports during pregnancy that specifically train the perineal muscles are associated with a lower rate of episiotomy and perineal lacerations ≥ 2nd degree.

scholarly journals Pre-soaking of hamstring grafts reduces risk of infection after ACL-reconstruction. A prospective study including 1000 patients

2018 ◽  
Vol 6 (4_suppl2) ◽  
pp. 2325967118S0003
Author(s):  
Christoph Offerhaus ◽  
Jürgen Höher ◽  
Maurice Balke
Keyword(s):  
Statistical Analysis ◽  
Prospective Study ◽  
Acl Reconstruction ◽  
Joint Infection ◽  
Risk Of Infection ◽  
Group 2 ◽  
A Prospective Study ◽  
Primary Acl Reconstruction ◽  
Hamstring Grafts ◽  
Group 1

Post-operative infection of the knee is one of the major concerns following ACL-reconstruction. The purpose of this study was to investigate whether the pre-soaking of hamstring grafts in vancomycin reduces the incidence of post-operative infection. This prospective study included more than 1000 patients undergoing primary ACL-reconstruction over a period of 4 years. Group 1 received intra-operative iv-antibiotics without pre-soaking of the graft. Group 2 received iv-antibiotics and additionally the graft was bathed in a vancomycin solution of 5 mg/mL. In group 1, a total of 2,3% of the patients suffered a post-operative joint infection. In contrast, there were no post-operative infections in the second group (0%). Statistical analysis revealed a significantly reduced post-operative infection rate when bathing the autograft in vancomycin. Pre-soaking of hamstrings grafts with vancomycin combined with classical iv antibiotic prophylaxis reduced the rate of post-operative infection when compared to iv-antibiotics alone. This technique should be utilized to reduce the overall incidence of knee infections following ACL reconstruction.

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