scholarly journals Thyroid function test in nephrotic syndrome children who are admitted in emergency ward of Government Tirunelveli Medical College and Hospital, India

2018 ◽  
Vol 5 (6) ◽  
pp. 2290
Author(s):  
J. Rukmani ◽  
C. Krishanamurthy ◽  
Denny Clarin
Keyword(s):  
Nephrotic Syndrome ◽  
Thyroid Function ◽  
Genetic Diseases ◽  
Congenital Nephrotic Syndrome ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Normal Limits ◽  
Function Test

Background: Nephrotic syndrome in childhood is largely primary or idiopathic, although a small proportion of cases are secondary to infectious agents and other glomerular and systemic diseases. The etiology of nephrotic syndrome is age-dependent. Most cases appearing in the first 3 months of life are referred as congenital nephrotic syndrome (CNS) and are due to genetic diseases. The objective of this study is to study the correlation between thyroid profile and different types of nephrotic syndrome.Methods: This cross-sectional study was done between March 2017 to October 2017 in the Department of Pediatrics Tirunelveli Government Medical College. 40 cases of nephrotic syndrome between 1 to12 years, which include all types of nephrotic syndrome. After history taking and clinical examination, blood samples were collected from the patients for thyroid function test and analyzed with standard techniques.Results: Serum T3, T4, TSH were found to be within normal limits. But TSH values in remission were significantly elevated compared to the first episode.Conclusions: Thyroid profiles in control were within normal range. The T4 and T3 levels in nephrotic syndrome were low and TSH was high. Hypothyroidism was more common in children less than 6 years. 

scholarly journals Thyroid Function in Molar Pregnancies

2022 ◽  
Vol 19 (1) ◽  
pp. 22-25
Author(s):  
Kavita Sinha ◽  
Ram Das ◽  
Homnath Adhikari
Keyword(s):  
Thyroid Function ◽  
Hydatidiform Mole ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Thyroid Storm ◽  
Molar Pregnancy ◽  
Cross Sectional ◽  
Medical College ◽  
Significant Burden ◽  
Gestational Trophoblastic Diseases

Introduction: Molar pregnancies represent a significant burden of disease on the spectrum of gestational trophoblastic diseases. Vaginal bleeding being the most common occasionally, molar pregnancy is complicated by hyperthyroidism, which may require treatment. Aims: To determine thyroid function test and association of hyperthyroidism among the cases of molar pregnancy. Methods: This is a hospital-based cross-sectional study conducted in the department of Obstetrics and Gynecology, Nepalgunj Medical College and Teaching Hospital, Kohalpur. Sixty cases of molar pregnancy were included during the study period from February 2020 to January 2021.Patients having history of known thyroid disorders were excluded. Results: Prevalence of molar pregnancy in our study was 5.4 per thousand pregnancies in our hospital. Molar pregnancy and hyperthyroidism, both were common in the age group of 21-35 years. Hyperthyroidism was present in 10% patients. Enlarged thyroid was seen in 3.3%, tremor was present in 3.3%, and palpitation in 21.5%. Five (8.3%) patients with hyperthyroidism were underweight. Majority of patients with hyperthyroidism, beta humanchorionic gonadotrophhin level was more than three lakhs and it was mostly associated with complete hydatidiform mole compared to partial hydatidiform mole. Thyroid storm was not experienced in any of the patients. Conclusion: The rate of molar pregnancy is high. Hyperthyroidism in molar pregnancy is not uncommon. High levels of human chorionic gonadotropin, complete hydatiform mole are directly associated with hyperthyroidism. Awareness of this condition is important for diagnosis and treatment to prevent life threatening complications.

scholarly journals Status of Thyroid Disorder among the Thyroid Function Test Samples Received in a Laboratory among Postmenopausal Women: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Manoranjan Shrestha ◽  
Reshmi Shrestha
Keyword(s):  
Postmenopausal Women ◽  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Reference Laboratory ◽  
Sectional Study ◽  
Cross Sectional ◽  
Function Test

Introduction: Thyroid dysfunction prevalence is high in females worldwide which increases with age. Postmenopausal and elderly women are particularly at risk of developing comorbidities and mortality related to thyroid dysfunction. We aimed to study the prevalence of thyroid dysfunction in postmenopausal women in the National Reference Laboratory of Nepal. Methods: A descriptive cross-sectional study was conducted in National Reference Laboratory from January 2019 to June 2019 including postmenopausal females, ≥49 years. The database of thyroid function test result was used for statistical analysis and proportion of thyroid dysfunction was calculated. The data was collected after approval from the institutional review committee. Statistical Package for Social Sciences version 21 was used to study descriptive data. Results: Out of a total of 160 postmenopausal females with thyroid function tests, 71 (44.4%) had thyroid dysfunction. Subclinical hypothyroidism was the frequently occurring thyroid dysfunction 51 (32%) followed by subclinical hyperthyroidism 13 (8%), hypothyroidism 3 (2%) and hyperthyroidism 3 (2%). In our study population, thyroid dysfunction peaked at 49 to 58 years of age interval 53 (33.1%) and subclinical hypothyroidism was the most frequent form 38 (23.7%). Conclusions: Subclinical hypothyroidism was the common thyroid dysfunction in postmenopausal age which peaked at 49 to 58 years of age group. Early postmenopausal females are predisposed to increased risk of comorbidities (cardiovascular disease, osteoporosis with high fracture, depression) which could be exacerbated with thyroid dysfunction; therefore awareness of thyroid dysfunction prevalence and thyroid screening for early management seems appropriate in Nepalese postmenopausal women.

scholarly journals Triiodothyronin, Thyroxine and Thyrotropin in Vitiligo

2012 ◽  
Vol 9 (2) ◽  
pp. 7-10
Author(s):  
K Subba ◽  
D Karn ◽  
R Khatri
Keyword(s):  
Thyroid Function ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Thyroid Function Tests ◽  
Thyroid Disorder ◽  
Age Group ◽  
Cross Sectional ◽  
Function Test ◽  
High Level

BackgroundVitiligo is a common pigmentary disorder of the skin, affecting individuals globally. Not only is this ailment psychologically incapacitating, it also has a high incidence of autoimmunity, signifying that its manifestations may be the portrayal of dysfunction of immune system. ObjectiveThe aim of this study is to find out the situations of abnormal thyroid function test (TFT) in vitiligo patients. MethodsA prospective cross sectional study was conducted at the Dhulikhel Hospital, KUTH, Dhulikhel during November 2008 to January 2011 with the objective to assess the thyroid function tests in vitiligo patients. ResultsTotal 66 vitiligo patients with male 30 (45%) and female 36 (55%). Total 26 (39.39%) vitiligo patients have been found to have abnormal thyroid function test. Among them 10 had abnormal T3, seven had abnormal T4 and 12 had abnormal TSH level. Thyroid function test were normal in other vitiligo patients. Total seven vitiligo had high level of T3 than normal value, four male and three female. Two had higher level of T4 above 2.0 ng/dl and all were male, while five had abnormally low level of T4 with three male and two female. There were seven vitiligo patient with increased T3 level and three with decreased T3 level, among them six were males and four were females, the age group was ranged from seven to 68 years old. The T4 level were found abnormal in seven vitiligo patients among which five were males and two were females with the age group ranging from 7 to 51 years. ConclusionsThere has been significant association of thyroid disorder in the patient with vitiligo. Therefore, patient with vitiligo need to undergo thyroid function test to rule out the thyroid disorder and prevent from long-term complications.DOI: http://dx.doi.org/10.3126/kumj.v9i2.6279Kathmandu Univ Med J 2011;9(2):7-10 

scholarly journals Hospital based study to evaluate subclinical hypothyroidism in post-menopausal women

2017 ◽  
Vol 5 (1) ◽  
pp. 153
Author(s):  
Shruthi Kamal V. ◽  
Rajesh S. ◽  
Reshma S.
Keyword(s):  
Postmenopausal Women ◽  
Subclinical Hypothyroidism ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Overt Hypothyroidism ◽  
Cross Sectional ◽  
Medical College ◽  
Menopausal Women ◽  
Function Test ◽  
Post Menopausal

Background: Very few studies have assessed prevalence of subclinical hypothyroidism in postmenopausal women. In this study, we aimed to assess the prevalence of subclinical hypothyroidism in postmenopausal women.Methods: Hospital based cross - sectional study carried out at Saveetha Medical College, Chennai, during the period of August 2016 to October 2016. Seventy-five women in General Surgery ward/OPD were included in the study. Subjects included in the study were postmenopausal age group between 45 to 85 years, provided they fulfilled inclusion and exclusion criteria. History was noted, serum Thyroid function test was done. Results were noted and analyzed.Results: Out of 75 subjects, 21.3% of postmenopausal women were having subclinical hypothyroidism.Conclusions: Prevalence of Subclinical hypothyroidism is high among postmenopausal women, which leads to overt hypothyroidism. Therefore, routine screening and treatment of this condition is must among postmenopausal women to prevent complications of subclinical hypothyroidism.

scholarly journals Evaluation of serum lipid profile in children with nephrotic syndrome admitted in emergency ward of Government Tirunelveli Medical College and Hospital, India

2018 ◽  
Vol 5 (6) ◽  
pp. 2244
Author(s):  
C. Krishanamurthy ◽  
J. Rukmani ◽  
Denny Clarin
Keyword(s):  
Nephrotic Syndrome ◽  
Lipid Profile ◽  
Serum Cholesterol ◽  
Cross Sectional Study ◽  
Clinical Findings ◽  
First Episode ◽  
Significant Elevation ◽  
Cross Sectional ◽  
Medical College ◽  
Normal Limits

Background: Nephrotic syndrome is a collection of clinical findings due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant edema. The objective of this study was to study the correlation between lipid profile and different types of nephrotic syndromeMethods: This cross-sectional study was done between March 2017 - October 2017 in the Department of Pediatrics, Tirunelveli Government Medical College. 40 cases of nephrotic syndrome between 1 to 12 years, which include all types of nephrotic syndrome. After history taking and clinical examination, blood samples were collected from the patients for lipid profile and analyzed with standard techniques.Results: In the 40 cases included in the present study mean serum albumin was low (mean = 2.212 gm %), mean total cholesterol (mean = 344.300 mg/dl) mean triglycerides (mean = 304.025 mg/dl) mean LDL (mean = 234.650 mg/dl) and mean VLDL (mean = 61.625 mg/dl) were elevated. HDL (mean = 46.07 mg/dl) with in normal limits. No significant changes observed.Conclusions: Serum cholesterol levels elevated significantly in relapse cases compared to the first episode. Serum cholesterol in SRNS cases shows statistically significant elevation compared to other types. LDL values were elevated in relapse cases compared to the first episode which were found out to be statistically insignificant. LDL values in SRNS cases show statistically significant elevation compared to first episodes and SDNS cases.

THYROID CYTOLOGY AND IT'S INTERPRETATION WITH THYROID FUNCTION TEST

2021 ◽  
pp. 80-82
Author(s):  
Dipti Debbarma ◽  
Shipra Singh ◽  
Debarshi Jana ◽  
Chittaranjan Dutta
Keyword(s):  
Thyroid Gland ◽  
Thyroid Function ◽  
Nodular Goiter ◽  
Thyroid Function Test ◽  
Total Serum ◽  
Endocrine Glands ◽  
Nodular Goitre ◽  
Medical College ◽  
Euthyroid State ◽  
Function Test

INTRODUCTION: The Thyroid gland is unique among the endocrine glands. It is the largest of all the endocrine glands and it is supercial in location. It is the only gland which is easily approachable to direct physical, cytological and histopathological examination. The thyroid gland is affected by a variety of pathological lesions that are manifested by various morphologies including developmental, inammatory, hyperplastic and neoplastic pathology which are quiet common in the clinical practice. AIM OFTHE STUDY:In this study, we aimed to assess the cytological ndings of palpable thyroid nodules in conjunction with thyroid hormonal prole of the patient. To study the incidence in relevance to age, sex in various categories of thyroid lesions. MATERIALS & METHODS: Study Design: Institutional based Cross-sectional Study. Duration of study: January 2019 to August 2020. Source of data: Patients presenting to the OPD and admitted in the In-patient ward at Darbhanga Medical College, Bihar. Place of study: Department of Pathology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Sample Size: 60 patients of enlarged thyroid gland. RESULTS & OBSERVATIONS: We found that the 53.3% Patients are in euthyroid state. Nodular goitre is the most common nding. In the present study among 60 patients, Nodular goiter accounts for 83.3 % of all cases; 41.7% of them were in euthyroid state, 21.7 % in hypothyroid state , 8.3 % in subclinical hypothyroid and remaining 11.7 % in hyperthyroid state . SUMMARY AND CONCLUSION: FNAC together with thyroid function test (TFT) analysis leads to early and accurate diagnosis of various thyroid diseases and reduces surgical intervention. The study showed that FNAcytologic diagnosis cannot be used to predict thyroid function using total serum T4, T3 and TSH concentrations. Measurement of TSH, free T4, and free T3 would be preferable

scholarly journals Screening of Thyroid Function in the First Half of Pregnancy

2016 ◽  
Vol 29 (1) ◽  
pp. 26-31
Author(s):  
Shaila Naznine Tania ◽  
Ferdousi Islam
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Thyroid Disorder ◽  
Eligibility Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
One Year ◽  
Serum Tsh

Objective: The study was conducted to find out any alterations in thyroid function status in first half of pregnancy (up to 20 weeks), with ultimate aim of deciding the usefulness of routine screening of thyroid function in pregnancy.Material and methods: A cross-sectional study was conducted in the department of Obstetrics & Gynaecology, Dhaka Medical College and Hospital, Dhaka, Bangladesh, over a period of one year from July 2011 to June 2012 on pregnant women in their 1st half of pregnancy to screen for the thyroid function. Based on predefined eligibility criteria, a total of 230 pregnant women were purposively included in the study. Thyroid function status was assessed by measuring serum levels of TSH, free thyroxine (FT4), and free tri-iodothyronine (FT3). Women with thyroid disorders were excluded.Results: The mean age of the patients being 24 years. Over 90% of the women were housewife and majority (88.7%) was educated. Over one-quarter of women was overweight with mean body mass index being 22.1 ± 4.4 kg/m2. The women were predominantly multigravida with 56% in 1st trimester 44% in the 1st half of 2nd trimester of pregnancy (13-20 weeks). Based on trimester’s specific range of serum TSH in the 1st and 1st half of 2nd trimester (13-20 weeks) of pregnancy,13% of the patients were hypothyroid and 3% were hyperthyroid thus yielding a total of 37(16%) pregnant women with abnormal thyroid function status.Conclusion: The study concluded that one in every six women may have thyroid disorder in the first half of pregnancy and subclinical hypothyroidism is four times more common than the subclinical hyperthyroidism.Bangladesh J Obstet Gynaecol, 2014; Vol. 29(1) : 26-31

scholarly journals Thyroid function status in patients with thyroid associated ophthalmopathy: a study for Nepal

2019 ◽  
Vol 3 (1) ◽  
pp. 3-9
Author(s):  
Saurav Piya ◽  
Jeena Gurung ◽  
Anadi Khatri
Keyword(s):  
Thyroid Function ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Health Concern ◽  
Common Symptom ◽  
Hypothyroid Patient ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
Equal Distribution ◽  
Thyroid Associated Ophthalmopathy

Introduction: Thyroid Eye Disease (TED) is an organ-specific autoimmune inflammatory incapacitating eye disorder usually associated with Graves’ disease affecting the orbit. Objectives: To determine thyroid function status in patients with thyroid-associated Ophthalmopathy. Methods: This is a hospital-based cross-sectional study of sixty three clinically diagnosed new cases of thyroid-associated ophthalmopathy done at Nepal Eye Hospital, Kathmandu from February 2012 to January 2013. Detailed history, systemic & ocular examination with special emphasis on evaluation of extraocular movement, lid signs, exophthalmos with Hertel's exophthalmometer was done. Thyroid function test and endocrine consultation were also done in all cases. Results: There were an equal distribution of TED with hyperthyroid (34.95%) and euthyroid status (34.95%). The most common presentation of both euthyroid and hypothyroid patient was tremor (13.4%) and palpitation (13.45%). The most common symptom of TED was foreign body sensation (54 %) but in TED with euthyroid and hypothyroid status, redness (22.2 %) and diminution of vision (20.6 %) were more frequent symptoms respectively. The most common presenting sign was Von Graefe’s sign (69 %). Among TED with hyperthyroid and hypothyroid status, Dalrymple's sign (29.3%) and Mobius sign (17.4%) were most common respectively. Conclusion: Thyroid-associated ophthalmopathy is an important health concern among patients with a thyroid disorder. TED with hyperthyroid states present more severely than hypothyroid and euthyroid states. As TED occurred with a high prevalence in all thyroid states, a close collaboration between endocrinologists and ophthalmologists along with timely referrals of patients with any eye complaint is mandated.

Sign in / Sign up

Export Citation Format

Share Document