scholarly journals Clinico-epidemiological features of Japanese encephalitis patients hospitalized in a tertiary care center

Author(s):  
Abu Hasan Sarkar ◽  
Bishnu Ram Das

Background: Japanese encephalitis (JE) is of particular interest as it has a high morbidity and mortality. Neurological sequale is the most dreaded damage caused by JE. It is a preventable disease with specific interventions. The objective of the study was to study the demography, clinical profile and outcome of patients with Japanese Encephalitis admitted to the wards of Internal Medicine and Pediatrics at Jorhat Medical College Hospital.Methods: Hospital based observational study for one year in Jorhat Medical College, Jorhat, Assam.Results: The mean age for JE was 32.25±27 years for male, 27.47±22 years for female and 29.94±24 years overall. Assessment of clinical signs and symptoms showed that fever and change in mental status were present in 100% of JE cases followed by neck rigidity in 79.3% and headache in 68.9%. 44.8% of JE cases had history of seizure, 37.9% had vomiting, 34.5% had irritability, 13.8% were unconscious. The peak of JE incidence occurred in the month of July (77.6%). Complete recovery was seen in 39.2%, followed by death in 32.6% and recovery with neurological sequalae in 28.2% at the time of discharge.Conclusions: Vigorous awareness activities should be carried out to sensitize people on prevention of JE. 

2006 ◽  
Vol 17 (4) ◽  
pp. 385-393 ◽  
Author(s):  
Ruth M. Kleinpell ◽  
Brian T. Graves ◽  
Michael H. Ackerman

Sepsis is a complex condition that occurs as a result of the systemic manifestation of infection. It is associated with high morbidity and mortality risks for critically ill patients. Assessment and monitoring aimed at early recognition and treatment, on the basis of evidence-based guidelines, are advocated for optimizing outcomes for patients with severe sepsis. Awareness of the risk factors, clinical signs and symptoms, pathophysiology, and updates in the management of sepsis can enhance the nursing care for patients with severe sepsis to promote best practices for sepsis care in the intensive care unit. This article reviews the incidence and pathophysiology of sepsis, highlighting updates in treatment and implications for nursing care.


2021 ◽  
Vol 6 (2) ◽  
pp. 283-285
Author(s):  
Deepika Kapil ◽  
Uday Mahajan

Serum uric acid has been recommended to screen gestational diabetes during pregnancy. Objective: Prediction of gestational diabetes by serum uric acid levels at 17-20 weeks. Methods: Eighty pregnant women who reported to the antenatal OPD at 17-20 weeks of period of gestation were enrolled in the study over the period of one year from Jan 2018 to Dec 2018 at Department of Obstetrics & Gynaecology Dr Rajendra Prasad Govt. Medical College, Kangra at Tanda, Himachal Pradesh, India. Results: Out of 8 patients, who developed GDM 4 (50%) had serum uric acid >3.5 mg/dl and 4 (50%) had serum uric levels <3.5 mg/dl. And the sensitivity of serum uric acid was 50% and specificity was 67%. Out of 8 patients, who developed GDM 4 (50%) had serum uric acid >3.5 mg/dl and 4 (50%) had serum uric levels <3.5 mg/dl. And the sensitivity of serum uric acid was 50% and specificity was 67%. Conclusion: Serum uric acid can be used to predict gestational diabetes. Keywords: Serum uric acid, gestational diabetes mellitus.


Author(s):  
Mukesh Kumar ◽  
Mukta Meel ◽  
Nikita Choudhary ◽  
Ashok Singh ◽  
Kusum Mathur

Abstract Background Nonneoplastic cysts of brain are a diverse group of benign lesions with variable etiopathogenesis. Due to different site and histogenesis, these lesions have wide clinicopathologic spectrum. Objective The study was performed to evaluate epidemiology and clinicopathologic spectrum of nonneoplastic central nervous system (CNS) cysts highlighting the role of histopathology in the diagnosis as well as to compare the data with other institution’s data available in literature. Materials and Methods All nonneoplastic CNS cysts reported from January 2013 to June 2020 in the Department of Pathology of Sawai Man Singh Medical College, Jaipur, were retrieved and reviewed. The data were evaluated for age, site, cyst wall lining, nature of cyst contents, and location (intracranial and spinal), using SPSS software version 20.0. Results A total of 255 cases were reviewed with an incidence of 4.96% and an age range of 2 to 74 years with slight male preponderance. Among them there were 157, 34, 26, 24, and 2 cases of epidermoid, arachnoid, dermoid, colloid, and glioependymal cysts, respectively, and 1 case of perineural cyst. Infective cysts were much less common than noninfective cysts, accounting for two cases of neurocysticercosis and hydatid cysts each. All cyst types mainly presented with signs and symptoms of a mass lesion. Conclusion Nonneoplastic cyst mainly presented like a CNS mass lesion with overlapping clinical features, and image finding revealing the key role of histopathological analysis. Epidermoids were the most common type of these cysts in the present series followed by the arachnoid cysts.


Author(s):  
Preeti Sharma ◽  
Neeta Chaudhary ◽  
Suchitra Singh

Background: Gestational diabetes mellitus is defined as any glucose intolerance with the onset or first recognition during pregnancy. Objectives of this study were to diagnose cases of GDM by screening with DIPSI criteria at less than 28 weeks. And observation and comparison of maternal and perinatal outcome in women diagnosed of GDM in less than 20 weeks and at 24-28 weeks.Methods: This was the prospective analytical study conducted in the department of obstetrics and gynecology for one year in Muzaffarnagar medical college and Hospital. After history taking, clinical and obstetrics examination 1503 antenatal patients of less than 28 weeks were enrolled underwent screening with DIPSI criteria. Out of which 80 patients with abnormal OGTT of gestational age less than 20 weeks and 69 patients with abnormal OGTT of gestational age 24 -28 weeks.Results: In early diagnosed GDM group alive and healthy babies were slightly lower as compared with late diagnosed GDM group.Conclusions: The diagnosis of GDM gives us an opportunity in identifying individuals who will be benefitted by early therapeutic intervention with diet, exercise, and normalizing the weight to delay or prevent the onset of the disease.


2017 ◽  
Vol 18 (2) ◽  
pp. 6-10
Author(s):  
Dipesh Kumar Gupta

Introduction: Quantification of lower urinary tract symptoms (LUTS) in patients with benign enlargement of prostate (BEP) is required to initiate and regulate treatment. Among many, International Prostate Symptom Score (IPSS) is standard though it is time consuming and difficult to understand by many patients. A recent Visual Prostate Symptom Score (VPSS) which is presumed to be simpler and well understood by patients with lower educational status has been in use.Methods: This is a prospective observational study conducted in Nepalgunj Medical College, Nepalgunj. In a total of 79 patients, 25 patients of LUTS because of other causes were excluded and 54 patients clinically diagnosed with BEP were enrolled for the study over a period of one year. Symptom evaluation was done in all with both IPSS and VPSS and uroflowmetry parameters were also recorded. The IPSS and VPSS were compared with each other and also with uroflowmetry parameters.Results: Mean age of the patients was 67 years and mean prostate volume was 48 gm. The patients who mostly were farmers had median eighth grade of education. Fourteen were illiterates and 40 were literate patients. Significant number of patients required assistance of a medical personnel to complete IPSS (p= <0.001) including those in literate group as well (p= <0.001). Time taken to complete VPSS was significantly less (p= 0.019). Total IPSS correlated with total VPSS ((r= +0.36; p=0.007). There was negative and significant correlation of VPSS with uroflowmeter parameters while IPSS failed to do so.Conclusion: VPSS is an easy and reliable tool to assess symptom severity in cases of BEP presenting with LUTS. It has the added advantage of utility in assessment of LUTS in patients with lower educational status. Moreover, the patients take shorter time to complete the questionnaire.  Journal of Society of Surgeons of Nepal, 2015; 18 (2), page: 6-10


1989 ◽  
Vol 12 (11) ◽  
pp. 688-691 ◽  
Author(s):  
R.J. Caruana

First-use reactions comprise a spectrum of adverse clinical signs and symptoms occurring in end-stage renal failure patients during hemodialysis treatments. This report describes four patients experiencing first-use reactions in the context of being referred to or from a tertiary care inpatient dialysis facility. Theories on the pathogenesis of first-use reactions are reviewed and recommendations for identifying patients at increased risk for this problem are proposed.


AYUSHDHARA ◽  
2020 ◽  
pp. 2815-2818
Author(s):  
Nisarga M S ◽  
Prakruthi G

Stye is an infection of the sebaceous glands of zeis at the base of the eye lashes, or an infection of the apocrine glands of moll. In Ayurvedic science, based on clinical signs and symptoms, stye can be correlated to Anjananamika where the symptoms include Dahatodavatitamrapidaka– i.e., boil which will be in Tamravarna associated with burning sensation and pricking sensation at Vartmapradesha i.e., in the lid and the other symptoms includes Mridvimandaruja– it will be soft and associated with mild pain. The line of treatment of the disease Anjananamika (stye) includes Swedana (hot compress), Nishpidana (pressure applying to drain out pus), Bhedana (incision), Pratisarana (rubbing of medicaments over the lids), Anjana (collyrium). The objective of the present study is to evaluate the effect of Bidalaka and Aschyotana along with internal medicines. A 19-year female patient approached the Shalakya tantra OPD of Sri Paripoorna Sanathana Ayurveda Medical College, Hospital and Research centre, Nelamangala, Bangalore with the complaints of swelling in the left eye lid since 3 days with mild pain and redness of the eyes. On examination, the whole edge of the left eye lid was oedematous along with the presence of an abscess in outer canthus. On these signs and symptoms, the patient was diagnosed as a case of stye and advised Kriyakalpa based on the Roga and Rogibala along with internal medicines which have given promising results with the complete absence of the symptoms within 10 days.


2021 ◽  
Vol 28 (09) ◽  
pp. 1229-1233
Author(s):  
Khadija Saleem ◽  
Tabinda Roheen ◽  
Faiza Wattoo ◽  
Sadia Ijaz ◽  
Farhan Javed ◽  
...  

Objective: The present study aims to assess the incidence of ovarian malignancies and its rise from 2010 to 2020 at subnational levels in tertiary care hospital in Faisalabad. Study Design: Retrospective Analysis. Setting: Madina Teaching Hospital, Faisalabad. Period: January 2010 and January 2020. Material & Methods: After the precise processing of data extracted from the Pakistan Cancer Registry and hospital records, annual standardized incidence and increasing trends were calculated during the period of the study. Results: A total of 103 patients of ovarian tumors were included in the study. During this period 550 oophorectomies were received out of 4752 (11.5%) gynecological admissions. 103 cases(18.73%) selected after formulating an inclusion criteria. The data showed 75 benign (74.25%) cases, 7 borderline tumors (6.93%) and 21 malignant tumors (20.79%). Age of patients ranged from 14-69 years. Out of all the benign tumors, serous cystadenomas were most common (45.33%) followed by mucinous cystadenomas (24%), dermoid cyst (30.66%). Commonest malignant tumor was serous cystadenocarcinoma (42.85%) followed by mucinous cystadenocarcinoma (33.33%) granulosa cell tumors (14.28%) krukenberg tumor (4.76%) and dysgerminoma (4.76%). Clinical signs and symptoms were mostly abdominal pain and distention. Conclusion: Ovarian malignancies are increasing in frequency at an early age with relatively longer duration of symptoms. This emphasizes the need of early detection and management because of desirability of maintaining patient’s menstrual and reproductive capabilities.


2017 ◽  
Vol 18 (2) ◽  
pp. 7
Author(s):  
Dipesh Kumar Gupta

<p><strong>Introduction: </strong>Quantification of lower urinary tract symptoms (LUTS) in patients with benign enlargement of prostate (BEP) is required to initiate and regulate treatment. Among many, International Prostate Symptom Score (IPSS) is standard though it is time consuming and difficult to understand by many patients. A recent Visual Prostate Symptom Score (VPSS) which is presumed to be simpler and well understood by patients with lower educational status has been in use.</p><p><strong>Methods: </strong>This is a prospective observational study conducted in Nepalgunj Medical College, Nepalgunj. In a total of 79 patients, 25 patients of LUTS because of other causes were excluded and 54 patients clinically diagnosed with BEP were enrolled for the study over a period of one year. Symptom evaluation was done in all with both IPSS and VPSS and uroflowmetry parameters were also recorded. The IPSS and VPSS were compared with each other and also with uroflowmetry parameters.</p><p><strong>Results: </strong>Mean age of the patients was 67 years and mean prostate volume was 48 gm. The patients who mostly were farmers had median eighth grade of education. Fourteen were illiterates and 40 were literate patients. Significant number of patients required assistance of a medical personnel to complete IPSS (p= &lt;0.001) including those in literate group as well (p= &lt;0.001). Time taken to complete VPSS was significantly less (p= 0.019). Total IPSS correlated with total VPSS ((r= +0.36; p=0.007). There was negative and significant correlation of VPSS with uroflowmeter parameters while IPSS failed to do so.</p><p><strong>Conclusion: </strong>VPSS is an easy and reliable tool to assess symptom severity in cases of BEP presenting with LUTS. It has the added advantage of utility in assessment of LUTS in patients with lower educational status. Moreover, the patients take shorter time to complete the questionnaire.  </p>


Author(s):  
Anchau Z.G. ◽  

Urinary schistosomiasis is a major public health problem particularly in developing countries and is associated with high morbidity. The study aimed at determining the prevalence of urinary schistosomiasis among Qur’anic school pupils in Zaria, Kaduna State. One hundred and fifty-five (155) urine samples were collected from Qur’anic school pupils in Zaria. The samples were immediately transported to the laboratory of the Department of Microbiology, Ahmadu Bello University (A.B.U), Zaria and processed using sedimentation technique. The ova of Schistosoma haematobium were detected in fifty-eight (58) samples giving a prevalence of 37.4%. The infection was highest in age group 10-12 years with 41.9%, followed by those in age range 13-15years (41.0%) while the least was observed among pupils between the ages of7- 9years (27.5%). Risk factors observed to be associated with schistosomiasis include; swimming in river or dam, fishing and place of laundry. The infection was associated with clinical signs and symptoms including abdominal pain, haematuria, painful and frequent urination. Regular community-based treatment should be conducted using anti-helminthic drugs to reduce urinary schistosomiasis. Key words: Prevalence, Schistosoma haematobium, Qur’anic school pupils, Zaria, Kaduna State


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