scholarly journals A clinical study on precancerous lesions of oral cavity in patients attending dental hospital, Telangana

Author(s):  
Soundarya Hanumakonda ◽  
Marri Swetha ◽  
Mallela Bhashitha ◽  
Harsha Mudigonda

Background: Aim of the retrospective study is to determine the type and frequency of the precancerous lesions of the oral cavity and to assess their sex, age distribution among the patients.Methods: Study was conducted based on year-wise data collected during 2015 to 2018 of all the patients with precancerous lesions of oral cavity.Results: The total number of patients was 1247, out of which 803 (64.39%) were males and 444 (35.60%) were females. Most common precancerous lesion is oral submucous fibrosis (70.24%) followed by oral lichen planus (19.08%), leukoplakia (8.98%), erythroplakia (1.68%).Conclusions: We observed marked geographical variation in the incidences of various precancerous lesions. Mostly males are affected by precancerous lesions than females.

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Arpita Kabiraj ◽  
Tanya Khaitan ◽  
Debarati Bhowmick ◽  
Uday Ginjupally ◽  
Aritri Bir ◽  
...  

Objective. Oral exfoliative cytology (OEC) has been implemented in the diagnosis of pathologic lesions for ages. The present study was undertaken to evaluate the cytomorphological features of some of the commonest potentially malignant disorders (leukoplakia, lichen planus, and oral submucous fibrosis) through a simple procedure and illustrate its importance in mass screening.Materials and Method. A total of 160 subjects with 25–50 years of age were included in the study. Among them, 40 were clinically diagnosed with oral leukoplakia, 40 were diagnosed with oral lichen planus, 40 were diagnosed with oral submucous fibrosis, and 40 were in the control group. The prepared smears were subjected to Papanicolaou stain and analyzed microscopically for the evaluation of the cytomorphological features.Results and Discussion. When analyzed microscopically, 36 (90%) out of the 40 oral leukoplakic lesions showed Class II cytological features whereas 4 (10%) revealed Class I features. Among 40 patients with oral lichen planus, 26 (65%) showed Class II features while the remaining 14 (35%) revealed Class I features. In 40 subjects with oral submucous fibrosis, 32 (80%) showed Class II features while the other 8 (20%) showed Class I features. All the 40 control subjects showed Class I features. Thus, OEC can be widely advocated as an addition to clinical conclusion and an adjunct to biopsy.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1766-1771
Author(s):  
Indra G ◽  
Maragathavalli G ◽  
Deepika Rajendran

Oral precancerous lesions and conditions like oral lichen planus, leukoplakia, or oral submucous fibrosis have the potential to develop into oral cancer. Oral cancer accounts for approximately 3 % of all malignancies. Oral lichen planus is a premalignant condition occurring in the oral cavity due to various factors. Blood investigations are routinely done minimally invasive procedures carried out for various diagnostic purposes. The study aims to identify if the complete blood count (CBC) can be used as a pathologic diagnostic marker in an oral premalignant disorder like oral lichen planus. A total of 64 patients (38 female, 26 male) were taken into the study between the period July 2019 - March 2020. Each patient is exposed to blood investigations, and their results are studied. The results of the study show a minimal variation in the blood results. In conclusion, to determine if it can be used as a pathological diagnostic marker in premalignant disorders like oral lichen planus, further studies must be carried out in larger populations.


2021 ◽  
Vol 10 (32) ◽  
pp. 2665-2671
Author(s):  
Falguni Patel ◽  
Shreyas N. Shah ◽  
Christina James

A common oral disease named as oral submucous fibrosis (OSMF) has the tendency to usually affect many areas of the oral cavity as well as involving the area of pharynx. The characteristic feature of oral submucous fibrosis is the fibrosis in submucosal area which involves maximum part of oral cavity leading to advanced lock jaw as a result of rigidity in cheeks, pharynx, lips and upper third part of the oesophageal canal progressing to dysphagia. It has been reported that OSMF occurs mainly in persons who are habituated to chew areca nut or products containing areca nut along with other ingredients. In recent years with the introduction of commercially available Gutka and other areca nut products, the incidence of OSMF is increasing especially in the younger generations. OSMF is irreversible and persists even after cessation of chewing habit and the severity increases along with the duration of habit. In 2007, the categorization of oral submucous fibrosis was done as a premalignant condition by WHO and it has higher chances of malignant transformation. Early diagnosis and application of proper treatment modality is mandatory to reduce morbidity and mortality rate. There are many classification systems that have been proposed in literature for oral submucous fibrosis, among which many are based on clinical features, some of them on functional aspects and others are based on histopathological aspects. Here is an attempt to enlighten the facts and recent updates of clinical, functional, histopathological features as well as pathogenesis and management of oral submucous fibrosis. The complete knowledge of oral submucous fibrosis is a useful to the clinicians as well as academicians and researchers for timely detection and proper management of the disease. KEY WORDS Oral Submucous Fibrosis, Precancerous Lesions, Precancerous Conditions, Sclerosing Stomatitis


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1259-1263
Author(s):  
Santosh Bala ◽  
Herald J. Sherlin ◽  
Vivek Narayan

The oral cavity is considered to be the window to your body because oral manifestations accompany many systemic diseases. In many instances, oral involvement precedes the appearance of other symptoms or lesions at other locations. The aim of this study is to find the correlation of these formative gingiva along with dermatological lesions. Details of patients reported with dermatological lesions to the dental hospital with oral manifestations were obtained from a detailed patient record. The data collected is tabulated graphically via SPSS for statistical analysis. 24 patients were reported with various dermatological lesions. 70% of female predilection was observed, and maximum patients carried the lesion for about 12 months. Out of the 24 patients, 70% show the presence of desquamative gingiva clinically. Histopathological diagnosis shows that 75% of the dermatological lesions present in the oral cavity is lichen planus. According to the current study population, dermatological lesions are the common cause of desquamative gingiva. The prevalence of oral lichen planus was higher and commonly seen along with desquamative gingiva.


Author(s):  
Ahmad Masoud ◽  
Muzzamil Shafique ◽  
Faiza Arif

Introduction: Oral submucous fibrosis (OSF) is a potentially malignant disorder of the oral cavity. Aims and Objectives: The core objective of the study is to analyze the oral submucous fibrosis with and without associated oral squamous cell carcinoma (OSCC). Materials and Methods: This cross sectional study was conducted in Baqai Dental College Karachi during October 2020 to June 2021. The data was collected from 100 patients of both genders who were confirmed with OSF on the basis of history and clinical examinations were included in the study. Demographic and clinical information were recorded. Results: The data were collected from 100 patients of both females and males. The age distribution of the sample was analyzed. The patients were mostly above 50 years of age in both categories. However, the number of patients who were with OSCC at an age below 50 was greater in the OSF-positive group (23.8% vs. 21.9%). Similarly, the mean age of OSF + OSCC patients was 57.5 years while this value was 59.5 years for those without. Conclusion: It is concluded that tumors show well-differentiated histology and less lymph node involvement. However, a statistical significance was not observed among these variables, when comparing the OSCC patients with OSF to those who are without.


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