scholarly journals The prevalence of anemia among the tribal children from the western districts of West Bengal, India

2021 ◽  
Vol 8 (2) ◽  
pp. 791
Author(s):  
Tuphan Kanti Dolai ◽  
Somnath Mondal ◽  
Manisha Jain ◽  
Prakas Kumar Mandal
Keyword(s):  
Vitamin B12 ◽  
West Bengal ◽  
Complete Blood Count ◽  
Significant Proportion ◽  
Serum Vitamin ◽  
Serum Folate ◽  
P Value ◽  
Cross Sectional ◽  
High Prevalence ◽  
Prevalence Of Anemia

Background: Tribal population in West Bengal constitutes a significant proportion (5.1%) and the vulnerable group because of lower socio-economic status, poor literacy rate and malnutrition. The present study was conducted to evaluate hemoglobin level and prevalence of anemia among the tribal children from the western districts of West Bengal, India.Methods: A cross-sectional study was conducted on school going (class I to class VIII) tribal children (≥5 to <13years) during March 2019 to February 2020. A complete blood count was done by automated blood cell counter and anemia was classified as per WHO criteria.  They were also tested for markers of common nutritional anemias (serum ferritin, serum vitamin B12 and serum folate). Data entry and analysis was done on SPSS version 15. A p-value of <0.05 was considered statistically significant.Results: Total 1, 010 tribal children were included with male:female=1:1.35. Among these, 46.34% (n=468) children had anemia. Among all anemic children 47.65% (n=223), 51.93% (n=243/468) and 0.42% (n=2) respectively had mild, moderate and severe anemia. There was a high prevalence (81.68%) of microcytic red blood cells in the total cohort; among anemic children, 53.94% have microcytosis while no macrocytosis was revealed. Among all grade anemias, iron, folate and vitamin B12 deficiency were found in 44.65% (n=209/468), 13.24% (n=62/468) and 25% (n=117/468) respectively.Conclusions: The prevalence of anemia among tribal children of West Bengal is a matter of concern. The high prevalence of microcytic indices in non-anemic population highlights the dire need for screening for the causes of anemia in this population. 

scholarly journals Kepatuhan Konsumsi Tablet Zat Besi Berdasarkan Tingkat Pengetahuan Ibu Hamil

2021 ◽  
Vol 12 (2) ◽  
pp. 173
Author(s):  
Fitriana Ikhtiarinawati Fajrin ◽  
Ayu Erisniwati
Keyword(s):  
Pregnant Women ◽  
Survey Method ◽  
P Value ◽  
Cross Sectional ◽  
High Prevalence ◽  
High Knowledge ◽  
Level Of Knowledge ◽  
Data Collection Technique ◽  
The Relationship ◽  
Prevalence Of Anemia

<p>One of the factors causing the high prevalence of anemia is the low compliance of pregnant women in consuming iron during pregnancy. The compliance of pregnant women in consuming iron during pregnancy cannot be separated from the level of knowledge that pregnant women have. This study aims to analyze the relationship between compliance with iron tablet consumption and the level of knowledge of pregnant women. This type of research is an analytical study with a survey method with a cross-sectional approach. The research was conducted on July 1-August 15, 2020, which was conducted at BPS Ernawati, Laren District, Lamongan Regency, with 21 respondents. The data collection technique used a questionnaire. Data analysis used fisher exact correlation test. Based on the results of the study, it showed that the majority had less knowledge about the importance of consuming iron tablets, namely as many as 10 respondents (47,6%). The majority of respondents did not comply with the consumption of iron tablets (57,1%). The majority of respondents with insufficient knowledge were not obedient, (38,1%), the majority of respondents with sufficient knowledge, were obedient as (19,1%), while the majority of respondents with high knowledge were obedient, (14,3%), and based on the statistical test results obtained p-value (0,033). This study concludes that there is a relationship between compliance with iron tablet consumption on the level of knowledge of pregnant women at BPS Diana Ernawati.  </p>

New and Robust Reference Ranges for Haematinics Measured on the Beckman-Coulter Access Analyser.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 3708-3708
Author(s):  
Lisa Wakeman ◽  
Roger Munro ◽  
John Lewis ◽  
Andrew Beddall ◽  
Ann Benton ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Normal Distribution ◽  
Serum Ferritin ◽  
Normal Population ◽  
Serum Vitamin ◽  
Serum Folate ◽  
P Value ◽  
Published Data ◽  
Reference Ranges ◽  
Square Root

Abstract Reference ranges (RRs) for haematinics need to be independently verified by individual laboratories since it has been shown that those quoted by some manufacturers may be inappropriate. The measurement of serum folate, ferritin and B12 remains a first-line investigation in the assessment of several pathologies. Establishing clearly defined, accurate reference ranges facilitates good interpretation and effective discrimination between health and disease thereby avoiding expensive and needless follow-up. Early morning venous samples were collected into Greiner Vacuette serum tubes (Ref: 456018) from 221 healthy laboratory personnel (F= 159;M = 62) aged 20–63 years for both gender. Age groups were equally represented. Serum vitamin B12, folate and ferritin were measured on all samples on a Beckman-Coulter Access analyser on the same day of collection. NCCLS guidelines (C28-A and H3-A4) were followed throughout. Outliers were excluded and data examined for normal distribution. The following normality checks were applied - Kurtosis, Kolmogorov-Smirnov and Shapiro-Wilk tests of normality, T-values (Skewness/SE Skewness), %diff from mean-median, histogram and normal curve, normal Q-Q probability plot and Box plot. Because all three parameters showed non-normal distribution, RRs were calculated using (1) the 2.5-and 97.5- percentiles, (2) the 2.5- and 97.5- percentiles on the transformed scale. The transformations, log natural, log10 and square root were applied to the variables and tested for normality. The transformation giving the best normal distribution was then selected. The non-parametric Mann-Whitney test was used to examine significant differences between males and females. Significant differences (p values shown below) are indicated by an asterisk. New Limits Historical Limits Manufacturers quoted RR Mann-Whitney U test (p value) (a) = Log natural; (b) = Log 10; (c) = square root RR (1) RR (2) Folate ng/mL M 2.1 – 14.7 2.1 (a) – 14.6 2.7–14.0 >3.0 0.016* F 2.7 – 18.1 2.7 (b) – 18.1 2.7–14.0 >3.0 Ferritin ng/mL M 11 – 215 11 (c) – 215 20.0–350 24–336 <0.05* F 5 – 119 5 (b) – 119 10.0–300 11–307 Vit B12 pg/mL M 113 – 567 113 (c) – 567 180–900 180–914 0.933 F 136 – 600 136 (b) – 600 180–900 180–914 It is vital that investigators use method-specific RRs in their own laboratories since those quoted by some manufacturers are inappropriate. Although our lower limits for serum ferritin appear to be low, they are in keeping with previously published data. A proportion of the normal population have low serum ferritin but are not anaemic nor symptomatic. This confusion between normality and iron deficiency continues to cause difficulties in interpretation. The range of vitamin B12 and folate concentrations in some healthy individuals overlap with those in symptomatic patients. It is useful therefore to quote “indeterminate” ranges. Our data indicates that such a range for vitamin B12 should be 130 – 160 since our distribution histogram (not shown) shows a clearly defined “flattened shoulder” between these values.

scholarly journals ANEMIA AND VITAMIN B12 DEFICIENCY IN ELDERLY.

2018 ◽  
Vol 11 (1) ◽  
pp. 402
Author(s):  
Zaozianlungliu Gonmei ◽  
Supriya Dwivedi ◽  
Gurudayal Singh Toteja ◽  
Karuna Singh ◽  
Naval Kishore Vikram ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Elderly Population ◽  
Serum Vitamin ◽  
Vitamin B12 Deficiency ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Serum Homocysteine ◽  
B12 Deficiency ◽  
Prevalence Of Anemia

 Objective: The present study was carried out to assess the prevalence of anemia, vitamin B12 deficiency and hyperhomocysteinemia among elderly in slums of West Delhi.Methods: A cross-sectional study was carried out among 234 elderly aged 60 and above in slums of West Delhi. 5 ml blood was collected from 116 elderly and was analyzed for hemoglobin, Vitamin B12 and homocysteine. Anemia was defined as hemoglobin <130 g/L and <120 g/l for male and female, respectively, Vitamin B12 deficiency as serum Vitamin B12 <203 pg/ml and hyperhomocysteinemia as serum homocysteine >15 μmol/l.Results: The overall prevalence of anemia, Vitamin B12 deficiency, and hyperhomocysteinemia among elderly was 57.76%, 36.36%, and 57.57%, respectively. Among anemic elderly, 33.33% and 64.15% had Vitamin B12 deficiency and hyperhomocysteinemia, respectively.Conclusion: More than half of the elderly population was anemic, while one-third was having Vitamin B12 deficiency.

scholarly journals Vitamin B12 Deficiency in Eastern India: A Hospital Based Cross-sectional Study

2021 ◽  
Author(s):  
Debasmita Bandyopadhyay ◽  
Jayati Roy Choudhury ◽  
Kasturi Mukherjee
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Vitamin B12 Deficiency ◽  
Cross Sectional Study ◽  
P Value ◽  
Eastern India ◽  
Cross Sectional ◽  
Severe Deficiency ◽  
B12 Deficiency ◽  
Mild Deficiency

Introduction: The prevalence of vitamin B12 deficiency is common (around 40%) in people older than 65 years of age and in people who are strict vegetarians. The major sources of Viamin B12 are meat, fish, dairy products and fortified cereals. Aim: To study the prevalence and common types of presentations of vitamin B12 deficiency among 20-80 years aged, non-vegetarian people attending a tertiary care hospital in a state of Eastern India. Materials and Methods: This hospital based cross-sectional study was conducted at IPGME&R and SSKM Hospital between July 2018 to December 2019. Serum samples were collected from 478 adult patients presenting with different symptoms like pallor, fatigue, numbness and tingling sensation in limbs, memory loss, alopecia etc., which may be related to vitamin B12 deficiency. These samples were screened for serum vitamin B12 level by chemiluminescence method in ADVIA, Centaur CP (SIEMENS). Data were analysed statistically by graph pad prism 8 software. Significance of the difference between means were detected using Student’s unpaired t-test and calculating the p-value (p-value <0.05 were considered as significant). Results: Among 184 females, 50 (27.17%) were found to be Vitamin B12 deficient (VBD). Among them, 18 (36%) had mild deficiency (serum vitamin B12 level 201-220 pmol/L), 22 (44%) had moderate (serum vitamin B12 level 150-200 pmol/L) and 10 (20%) had severe deficiency (serum vitamin B12 level <150 pmol/L). A total of 35 (70%) of the VBD females were of <50 years of age. Among 294 males, 83 (28.23%) were found to be VBD. Among them, 34 (41%) had mild deficiency (serum vitamin B12 level 201-220 pmol/L), 36 (43%) had moderate (serum vitamin B12 level 150-200 pmol/L) and 13 (16%) had severe deficiency (serum vitamin B12 level <150 pmol/L). Total 43 (51.8%) of VBD male persons were of <50 years age. Among VBD female patients, 24 (48%) had neuropathy and among VBD male patients, 54 (65%) had neuropathy. Conclusion: So, it can be concluded that if regular screening is done for serum vitamin B12 in symptomatic patients irrespective of age, a number of problems can be reduced or cured by diagnosing VBD patients and treating them with vitamin B12 either by dietary modification or medicinal supplementation.

Indigenous indicators of vitamin B12 deficiency

2020 ◽  
Vol 8 (2) ◽  
pp. 38-46
Author(s):  
Deepak Kumar P ◽  
Darshana Makwana ◽  
Pragathi Pragathi
Keyword(s):  
Vitamin B12 ◽  
Complete Blood Count ◽  
Clinical Manifestations ◽  
Serum Vitamin ◽  
Vitamin B12 Deficiency ◽  
Screening Tests ◽  
Mean Corpuscular Hemoglobin ◽  
Cross Sectional ◽  
Predictive Values ◽  
B12 Deficiency

Introduction: Clinical manifestations of vitamin B12 deficiency are mostly non-specific. An entity called subclinical deficiency has become popular where the need has arisen to perform costly investigations which indicate functional deficiency of vitamin B12 even when vitamin B12 levels are normal. These factors pose a challenge in planning management of patients. Aims and objectives : The study was conducted as an attempt to identify affordable and credible laboratory indicators of vitamin B12 deficiency which can be used as screening tests before choosing patients for further evaluation or treatment. Material and Methods : This was a time bound cross-sectional study where 100 adult patients who had undergone the following investigations were randomly chosen: Complete Blood Count with red cell indices, serum bilirubin and serum vitamin B12 levels. The sensitivity, specificity and predictive values (positive-PPV and negative-NPV) of the variables that could hypothetically identify vitamin B12 deficiency, both individually or in combinations were calculated and compared. Results and conclusion : Hemoglobin, MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Hemoglobin), platelets and bilirubin were not equally distributed between vitamin B12 deficient and normal groups(p values for these variables were 0.029, 0.000, 0.000, 0.003 and 0.029 respectively).When these variables were tested individually and in combination, the combination of [MCV=95 fl or MCH=30 pg or Platelets =1.4 lakh/µl or Bilirubin =1 mg/dl] had sensitivity of 68.2%, specificity of 85.7%, PPV of 78.9% and NPV of 77.4%. This proposed combination used as a screening test has potential for wide application considering its simplicity and cost advantage.

scholarly journals ANEMIA AND VITAMIN B12 DEFICIENCY IN ELDERLY.

2018 ◽  
Vol 11 (1) ◽  
pp. 402 ◽  
Author(s):  
Zaozianlungliu Gonmei ◽  
Supriya Dwivedi ◽  
Gurudayal Singh Toteja ◽  
Karuna Singh ◽  
Naval Kishore Vikram ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Elderly Population ◽  
Serum Vitamin ◽  
Vitamin B12 Deficiency ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Serum Homocysteine ◽  
B12 Deficiency ◽  
Prevalence Of Anemia

 Objective: The present study was carried out to assess the prevalence of anemia, vitamin B12 deficiency and hyperhomocysteinemia among elderly in slums of West Delhi.Methods: A cross-sectional study was carried out among 234 elderly aged 60 and above in slums of West Delhi. 5 ml blood was collected from 116 elderly and was analyzed for hemoglobin, Vitamin B12 and homocysteine. Anemia was defined as hemoglobin <130 g/L and <120 g/l for male and female, respectively, Vitamin B12 deficiency as serum Vitamin B12 <203 pg/ml and hyperhomocysteinemia as serum homocysteine >15 μmol/l.Results: The overall prevalence of anemia, Vitamin B12 deficiency, and hyperhomocysteinemia among elderly was 57.76%, 36.36%, and 57.57%, respectively. Among anemic elderly, 33.33% and 64.15% had Vitamin B12 deficiency and hyperhomocysteinemia, respectively.Conclusion: More than half of the elderly population was anemic, while one-third was having Vitamin B12 deficiency.

VITAMIN B12 AND FOLIC ACID VALUES IN PREMATURE INFANTS

PEDIATRICS ◽  
1972 ◽  
Vol 50 (4) ◽  
pp. 584-589
Author(s):  
Ambadas Pathak ◽  
Herman A. Godwin ◽  
Luis M. Prudent
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Premature Infants ◽  
Serum Vitamin ◽  
Serum Folate ◽  
Born Infant ◽  
Low Concentrations ◽  
Folate And Vitamin B12 ◽  
Relationship Of ◽  
The Relationship

The relationship of serum vitamin B12 and folic acid was studied in 24 premature infants. In 14 of the 24, low serum vitamin B12 values were found around 40 days of age. Serum folic acid concentrations were less frequently depressed and were usually associated with normal red cell folate values. No correlation between hematocrits and vitamin B12 or folate levels was found. It is suggested that low concentrations of serum folate and vitamin B12 result from low dietary intake coupled with increased demand by the prematurely born infant.

scholarly journals Factors Associated with Physical Activity among Medical Students of Jazan University: A Cross-Sectional Study

2017 ◽  
Vol 9 (4) ◽  
pp. 266 ◽  
Author(s):  
Husam Eldin Elsawi Khalafalla ◽  
Mohamed Salih Mahfouz ◽  
Muath Hassan Ibrahim Najmi ◽  
Sayyaf Abdullah Mohammad Najmi ◽  
Qasem Ali Yahya Arishi ◽  
...  
Keyword(s):  
Physical Activity ◽  
Medical Students ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Affecting ◽  
High Prevalence ◽  
The University ◽  
Study Participants

BACKGROUND: Physical activity is one of the most important factors that affect human health; it reduces the chances of hypertension, coronary heart disease, stroke, diabetes, breast and colon cancer, and depression.OBJECTIVES: The objectives of this study were to measure prevalence of physical activity and to determine the factors affecting the level of physical activity among medical student in Jazan University.METHODS: A cross-sectional study was conducted among the students of medical colleges of Jazan University. A random sample of 419 was determined using most recent physical activity prevalence. A validated self-administered questionnaire was used for data collection.RESULTS: There is a high prevalence of inactivity among study participants (88.1%). Females (91.7%) were more significantly (p value=0.013) inactive than males (83.8%). The most influential barrier perceived by participants is (heavy) academic work as well as lack of places for physical activity; the latter factor being more effective in hindering female students' physical activity.CONCLUSION: Results revealed that the inactivity rate was very high among medical students. The results of this study call for a well-planned intervention at the university level for improving the level of physical activity among university students.

High prevalence of low serum vitamin B12 in a multi-ethnic Israeli population

2001 ◽  
Vol 115 (3) ◽  
pp. 707-709 ◽  
Author(s):  
Y. Gielchinsky ◽  
D. Elstein ◽  
R. Green ◽  
J. W. Miller ◽  
Y. Elstein ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Serum Vitamin ◽  
Israeli Population ◽  
High Prevalence ◽  
Low Serum

scholarly journals Sputum smear positivity grade and chest X-ray findings in tuberculosis: A cross-sectional study

2021 ◽  
Author(s):  
R. Behzadmehr ◽  
E. Nejadkehkha
Keyword(s):  
Cross Sectional Study ◽  
Health Concern ◽  
Sputum Smear ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Radiographic Findings ◽  
X Ray ◽  
High Prevalence ◽  
Chest X Ray

Despite many advances in the diagnosis, screening, and rapid treatment of tuberculosis, it is still a public health concern in the world. Due to the importance of this issue in diagnosis and reduction of transmission of infection and treatment of the disease especially where this study is conducted due to the high prevalence of tuberculosis, this study was done to determine The relationship between sputum smear positivity grade and chest X-ray findings in pulmonary tuberculosis patients in a hospital in southeast of Iran. This cross-sectional study was performed on all patients with pulmonary TB referencing the health centers in Zabol city, southeast of Iran from 1 January 2015 to 30 December 2020. Sputum smear and radiographic findings of the chest X-ray were evaluated. Data was collected using a form of information and finally analyzed by SPSS 22. Out of 101 patients examined in the present study, 71 were women and 30 were men. The mean age of the patients was 62.68 ± 13.61 years. The frequency of opacity in patients with grades 1, 2, and 3 was 71.4, 78.5, and 76.5%, respectively. Frequency of cavitation in patients with Grade 1, 2 and 3 was 11.5%, 28.5% and 52.9% respectively (P value 0.001). The frequency of reticulonodular presentations in patients with grade 1, 2, and 3 was 24.2, 7.1, and 0%, respectively.  In general, the results of this study showed that, with increasing grading of smears (1+, 2+, and 3+), the frequency of cavitation presentation increased significantly and the frequency of reticulonodular presentations decreased significantly. In general, the results of this study showed that, with increasing grading of smears (, the frequency of Cavitation presentation increased significantly and the frequency of reticulonodular presentations decreased significantly. The findings of the present study can help physicians better diagnose TB.

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