scholarly journals Zero prevalence of hepatitis B and hepatitis C infections in clinicopathologically proven lichen planus cases: a cross sectional study at a tertiary care centre in south India

2017 ◽  
Vol 3 (3) ◽  
pp. 351 ◽  
Author(s):  
Lekshmi Sajini ◽  
Gopikrishnan Anjaneyan ◽  
Soumya Jagadeesan ◽  
Vinitha Varghese Panicker ◽  
Sreedevan V. ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Lichen Planus ◽  
Tertiary Care ◽  
Unknown Etiology ◽  
Study Group ◽  
Inflammatory Disorder ◽  
Hepatitis C Infection ◽  
Cell Degeneration ◽  
The World

<p class="abstract"><strong>Background:</strong> Lichen planus (LP) is a common chronic mucocutaneous inflammatory disorder of unknown etiology. Several editorials, chapters, studies have suggested an association between hepatitis C virus and hepatitis B virus (to a lesser extent) in LP. This association was not seen in various parts of the world including India.</p><p class="abstract"><strong>Methods:</strong> Patients attending the dermatology outpatient department with lichen planus confirmed by histopathologic examination were included in the study and along with clinic-epidemiological data, all the patients were tested for hepatitis B and hepatitis C infection.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 84 patients of clinico-pathologically proven lichen planus were included in the study out of which 31 were males and 53 were females. The most common age group of lichen planus in our study group was 40-50 years. Major histopathological findings were basal cell degeneration (92.7%), hyperkeratosis (89%), pigment incontinence (73%) and lymphohistiocytic infiltration (70%). All patients in this study group tested negative for HBsAg and anti-HCV antibodies.</p><p><strong>Conclusions:</strong> Although numerous studies around the world have suggested an association between HCV and HBV infections with lichen planus- multiple subsequent studies including the present study shows contrasting results especially in this part of the world. The authors believe routine screening of lichen planus patients for presence of hepatitis B and hepatitis C infection is not warranted, particularly in Indian population. </p>

scholarly journals Relationship of Lichen Planus, Hepatitis Virus C and Low Level of Total Antioxidant Capacity

2018 ◽  
Vol 15 (5) ◽  
pp. 23-32
Author(s):  
Simona Roxana Georgescu ◽  
Alina Musetescu ◽  
Corina Daniela Ene ◽  
Cosmin Ene ◽  
Mădălina Mitran ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Antioxidant Capacity ◽  
Lichen Planus ◽  
Total Antioxidant Capacity ◽  
Complex Disease ◽  
Hepatitis Virus ◽  
Antioxidant Systems ◽  
Inflammatory Disorder ◽  
Hepatitis C Infection ◽  
Total Antioxidant

AbstractBased on the latest medical research, it is supposed that lichen planus is an inflammatory disorder, associated with autoimmune diseases, hepatitis C infection, oxidative stress or antioxidant deficiency. The purpose of the present work is to determine a panel of serum antioxidants, possibly involved in the development/persistence of the disease. The determination of extracellular antioxidants (bilirubin, uric acid, albumin, iron, transferrin, ferritin, copper, ceruloplasmin, total antioxidant capacity) in patients with lichen planus during exacerbations have revealed a significant reduction in non-enzymatic antioxidant systems. Hepatitis C virus enhances the deficit of antioxidants in patients with lichen planus. Based on these findings, the authors consider that lichen planus is a complex disease of unidentified cause and its pathogenic mechanisms are still incompletely elucidated. It may be speculated that several interconnected mechanisms are involved in the onset and evolution of lichen planus.

Assessment of Knowledge Regarding Hepatitis C Virus among Medical Students in a Tertiary Care

2020 ◽  
Vol 5 (8) ◽  
pp. 26-31
Author(s):  
Aradhya Abrol ◽  
Surbhi Abrol ◽  
Abhinav Goyal ◽  
Savita Mahajan ◽  
Ram Kishan Abrol ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Tertiary Care ◽  
Hepatitis C Virus Infection ◽  
Hepatitis C Infection ◽  
Cross Sectional ◽  
Knowledge Based ◽  
Health Care Burden ◽  
The World ◽  
Hcv Transmission

Hepatitis C virus infection is a globally prevalent pathogen and is a major cause of health care burden in India. HCV is affecting about 170 million people annually throughout the world. The estimated prevalence of HCV in India is about 0.5-1.5% and is a leading cause of chronic liver disease and hepatocellular carcinoma rapidly transmitting as silent killer.This study was planned with an aim to determine awareness about Hepatitis C infection among medical students.A cross-sectional questionnaire-based survey containing 30 questions to assess the knowledge about Hepatitis C infection was conducted.Total 125 students participated, overall score of knowledge-based questions and about transmission of HCV infection were satisfactory. Majority of students were aware of HCV transmission and prevention but have not shown good results about laboratory diagnosis.Overall grasp of Hepatitis C by the studied group was good. However, there were serious gap in their knowledge of lab diagnosis which need to be filled. Knowledge about transmission was very good

scholarly journals Hepatitis B & C Viral Markers Status in Icteric Children at a Tertiary Care Hospital

2012 ◽  
Vol 3 (2) ◽  
pp. 35-37 ◽  
Author(s):  
Abdul Matin ◽  
Md. Rafiqul Islam ◽  
Md. Al-Amin Mridha ◽  
Md. Golam Mowla ◽  
Rita Khan ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Venous Blood ◽  
Tertiary Care ◽  
High Rate ◽  
Seroprevalence Rate ◽  
Care Hospital ◽  
Age Group ◽  
Hepatitis C Infection ◽  
Medical University

Background: Hepatitis B (HBV) and Hepatitis C virus (HCV) can cause important morbidity and mortality and are major causes of acute and chronic liver disease worldwide.Objectives: This study was an attempt to evaluate the seroprevalence rate of hepatitis B and C in jaundiced children who were admitted at Bangabandhu Sheikh Mujib Medical University. This would be helpful to take measure for the prevention of hepatitis B and hepatitis C infection in paediatric age group. Methodology: A total of 50 admitted jaundiced children of either sex selected randomly were studied during July 2004 to June 2005 in the Department of Paediatrics of Bangabandhu Sheikh Mujib Medical University. Venous blood was tested for HBsAg and anti-HBcAb (IgM) and anti-HCV viral markers by ELISA.Results: The HBsAg test was positive among 24.0 %, Anti-HBcAb (IgM) test positive in 14.0 %. HBsAg was positive in 66.66% of male children and 33.33% of female children. Sero positivity was more in the 10 years age group. Conclusion: This study shows high rate of HBsAg and Anti- HBcAb IgM seropositivity among icteric sick children so, further studies with appropriate design & sample size to be conducted. J Shaheed Suhrawardy Med Coll, 2011;3 (2): 35-37 DOI: http://dx.doi.org/10.3329/jssmc.v3i2.12075

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

Historical study of acute hepatitis B in subjects with or without hepatitis C infection

2012 ◽  
Vol 23 (6) ◽  
pp. e146-e149 ◽  
Author(s):  
Tommaso Stroffolini ◽  
Maria Rapicetta ◽  
Flavia Lombardo ◽  
Paola Chionne ◽  
Elisabetta Madonna ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Acute Hepatitis ◽  
Historical Study ◽  
Hepatitis C Infection ◽  
Acute Hepatitis B
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