scholarly journals Hepatitis B & C Viral Markers Status in Icteric Children at a Tertiary Care Hospital

2012 ◽  
Vol 3 (2) ◽  
pp. 35-37 ◽  
Author(s):  
Abdul Matin ◽  
Md. Rafiqul Islam ◽  
Md. Al-Amin Mridha ◽  
Md. Golam Mowla ◽  
Rita Khan ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Venous Blood ◽  
Tertiary Care ◽  
High Rate ◽  
Seroprevalence Rate ◽  
Care Hospital ◽  
Age Group ◽  
Hepatitis C Infection ◽  
Medical University

Background: Hepatitis B (HBV) and Hepatitis C virus (HCV) can cause important morbidity and mortality and are major causes of acute and chronic liver disease worldwide.Objectives: This study was an attempt to evaluate the seroprevalence rate of hepatitis B and C in jaundiced children who were admitted at Bangabandhu Sheikh Mujib Medical University. This would be helpful to take measure for the prevention of hepatitis B and hepatitis C infection in paediatric age group. Methodology: A total of 50 admitted jaundiced children of either sex selected randomly were studied during July 2004 to June 2005 in the Department of Paediatrics of Bangabandhu Sheikh Mujib Medical University. Venous blood was tested for HBsAg and anti-HBcAb (IgM) and anti-HCV viral markers by ELISA.Results: The HBsAg test was positive among 24.0 %, Anti-HBcAb (IgM) test positive in 14.0 %. HBsAg was positive in 66.66% of male children and 33.33% of female children. Sero positivity was more in the 10 years age group. Conclusion: This study shows high rate of HBsAg and Anti- HBcAb IgM seropositivity among icteric sick children so, further studies with appropriate design & sample size to be conducted. J Shaheed Suhrawardy Med Coll, 2011;3 (2): 35-37 DOI: http://dx.doi.org/10.3329/jssmc.v3i2.12075

The seroprevalence of HIV, hepatitis B, hepatitis C and venereal disease research laboratory test seropositivity in blood donors: a 5-year retrospective comparative study at tertiary care hospital in Mumbai, Maharashtra, India

2017 ◽  
Vol 5 (6) ◽  
pp. 2662
Author(s):  
Khaneta Parveen ◽  
Abdul Faheem Khan ◽  
Abdul Salim Khan
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Blood Donors ◽  
Blood Donation ◽  
Venereal Disease ◽  
Tertiary Care ◽  
Seroprevalence Rate ◽  
Care Hospital ◽  
Total Blood ◽  
Retrospective Comparative Study

Background: The high seroprevalence of transfusion-transmitted infectious (TTI) diseases such as HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis in India affects the safety of blood for recipients. This study was undertaken with the aim to screen the blood donor’s demographic profile and to estimate seroprevalence of HIV, HBV, HCV and VDRL transmissible by blood transfusion in voluntary and replacement male and female blood donors during the last 5 year period.Methods: The present study was conducted over a period of 5 years (2001-2005) and involved 1,53,020 blood donors including both (voluntary, replacement males and females) who were thoroughly screened and selected for blood donation in blood bank at Departments of Pathology, Seth GS Medical College and KEM hospital, Mumbai, Maharashtra, India.Results: Total five years seropositivity for all four disease marker in all blood donors was 9150 (5.97%). The incidence of HIV seropositivity was 1995 (1.30%), the seroprevalence of HBV in total blood donor was 4673 (3.05%), HCV consist of 1599 (1.04%), and VDRL seropositivity was least, i.e. 883 (0.57%). Out of total 9150 (5.97%) seropositive blood donors, 24 (0.26%) blood donors showed concomitant seropositivity for more than one of the blood transmissible diseases.Conclusions: Seroprevalence rate of all the four blood transmissible diseases was higher in replacement donors, and lower in voluntary group of donors. Therefore, it has been evaluated that the voluntary blood donation is safer and promoted for safe blood donation in comparison to replacement blood donation.

scholarly journals Sero Positivity of Hepatitis B & C Markers Among Non-Icteric Children Attending A Tertiary Hospital in Dhaka City

2012 ◽  
Vol 36 (1) ◽  
pp. 11-15
Author(s):  
Abdul Matin ◽  
Md Rafiqul Islam ◽  
Ranjjt Ranjan Roy ◽  
Md Golam Mowla ◽  
ABM Shahidul Alam ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Venous Blood ◽  
Public Health Problem ◽  
Developed Countries ◽  
Tertiary Hospital ◽  
High Rate ◽  
Primary Hepatocellular Carcinoma ◽  
Major Public Health Problem ◽  
Seroprevalence Rate ◽  
Medical University

Background: Viral hepatitis is a major public health problem both in developing and developed countries. Hepatitis B (HBV) and C (HCV) viruses can cause important morbidity and mortality and are major causes of acute and chronic liver diseases worldwide and often leads to cirrhosis or primary hepatocellular carcinoma. The prevalence of infection varies from country to country and within countries. Aim & objectives: This study was an attempt to evaluate the seroprevalence rate of hepatitis B and C in non-jaundiced children who were admitted at Bangabandhu Sheikh Mujib Medical University. Methods: A total of 100 non-icteric admitted children with different childhood diseases of either sex selected randomly were studied during July 2004 to June 2005 in the Department of Pediatrics and Microbiology, Bangabandhu Sheesikh Mujib Medical University. Venous blood was tested for HBsAg and anti-HBc (IgM) and anti-HCV viral markers by ELISA technique using kits from Dia Sorin S.n.I, Italy. Results: The HBsAg test was positive among 19.0 %, Anti-HBc (IgM) test positive in 11.0 % and Anti-HCV test positive in 2.0 % non-icteric admitted children. Positivity was higher in male children. HBsAg was positive in 68.4% of male children and 31.5% of female children. Sero positivity was more in the 5-9 years age group. Noseroposivity was related to blood and blood products transfusion in cases of hepatitis B infection. Conclusion: As this study shows high rate of HBsAg and Anti-HBc (IgM) seropositivity among non-icteric sick children, so further studies with appropriate design & sample size are to be conducted. DOI: http://dx.doi.org/10.3329/bjch.v36i1.13027 Bangladesh J Child Health 2012; Vol 36 (1): 11-15

Prescribing trends of antidiabetic drugs in diabetic and hypertensive diabetic patients in an urban tertiary care hospital of Bangladesh

2017 ◽  
Vol 3 (3) ◽  
pp. 338-343
Author(s):  
Mohammad Didar Khan ◽  
Md. Ibrahim ◽  
Md. Mizanur Rahman Moghal ◽  
Dipti debnath ◽  
Asma Kabir ◽  
...  
Keyword(s):  
Urban Areas ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Age Group ◽  
Microsoft Excel ◽  
Patient Profile ◽  
Prescribing Trends ◽  
Medical University ◽  
Insight Into

Objective: The present epidemiological study was conducted with the objectives of providing an insight into the current use of antidiabetic medications to diabetics and hypertensive diabetics in urban areas and determining how the patient factors influence the prescribing of antidiabetic medications. Methodology: Data of patients of past two years were collected from Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital, Dhaka, Bangladesh. The details were entered in the structured patient profile form. Data were statistically analyzed using the Microsoft Excel 2007 software. Result: A total of 958 patient’s data were collected and analyzed of which 632 (65.97 %) were males and 326 (34.03 %) were females. These patients were further categorized based on their age. 330 patients (34.45 %) belonged to the age group 20 – 44 years, 504 (52.61 %) to the age group 45 – 65 years and 124 (12.94 %) to the age group 65 – 80 years. 684 (71.4%) patients out of the 958 patients studied were suffering from coexisting hypertension. Co-existing hypertension was found to be more prevalent in the age group 45 – 65 years (67.69%) and was found more in females (84.04%). Conclusion: Metformin was the oral hypoglycemic which was the highest prescribed. In hypertensive diabetics Metformin and Pioglitazone were most frequently prescribed drugs. Biguanides and Insulin were the most commonly prescribed antidiabetics. A combination of two or more drugs of different classes was prescribed to hypertensive diabetics. It is necessary to have an improved understanding of the etiology and pathophysiology of diabetes to focus on research efforts appropriately.

scholarly journals Zero prevalence of hepatitis B and hepatitis C infections in clinicopathologically proven lichen planus cases: a cross sectional study at a tertiary care centre in south India

2017 ◽  
Vol 3 (3) ◽  
pp. 351 ◽  
Author(s):  
Lekshmi Sajini ◽  
Gopikrishnan Anjaneyan ◽  
Soumya Jagadeesan ◽  
Vinitha Varghese Panicker ◽  
Sreedevan V. ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Lichen Planus ◽  
Tertiary Care ◽  
Unknown Etiology ◽  
Study Group ◽  
Inflammatory Disorder ◽  
Hepatitis C Infection ◽  
Cell Degeneration ◽  
The World

<p class="abstract"><strong>Background:</strong> Lichen planus (LP) is a common chronic mucocutaneous inflammatory disorder of unknown etiology. Several editorials, chapters, studies have suggested an association between hepatitis C virus and hepatitis B virus (to a lesser extent) in LP. This association was not seen in various parts of the world including India.</p><p class="abstract"><strong>Methods:</strong> Patients attending the dermatology outpatient department with lichen planus confirmed by histopathologic examination were included in the study and along with clinic-epidemiological data, all the patients were tested for hepatitis B and hepatitis C infection.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 84 patients of clinico-pathologically proven lichen planus were included in the study out of which 31 were males and 53 were females. The most common age group of lichen planus in our study group was 40-50 years. Major histopathological findings were basal cell degeneration (92.7%), hyperkeratosis (89%), pigment incontinence (73%) and lymphohistiocytic infiltration (70%). All patients in this study group tested negative for HBsAg and anti-HCV antibodies.</p><p><strong>Conclusions:</strong> Although numerous studies around the world have suggested an association between HCV and HBV infections with lichen planus- multiple subsequent studies including the present study shows contrasting results especially in this part of the world. The authors believe routine screening of lichen planus patients for presence of hepatitis B and hepatitis C infection is not warranted, particularly in Indian population. </p>

Increasing Seroprevalence of Hepatitis C Virus among Blood Donors - A 3 Year Study in North India

2021 ◽  
Vol 8 (07) ◽  
pp. 379-383
Author(s):  
Jagjeewan Ram ◽  
Namrata Nigam ◽  
Aparna Singh ◽  
Lubna Khan
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Tertiary Care ◽  
North India ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
Hepatitis C Infection ◽  
Case Volume

BACKGROUND The primary aspect of blood transfusion lies in the availability of blood and blood components which are tested and reported negative for transfusion transmitted infections (TTI’s). The increased seroprevalence of TTI’s indicate their prevalence in general public. The study was conducted to analyse the increasing seroprevalence of hepatitis C virus (HCV) over a period of 3 years. The objectives of the study determine the seroprevalence of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) among the voluntary blood donors at a tertiary care hospital & associated blood bank. METHODS This cross-sectional study was done at the Department of Transfusion Medicine, GSVM Medical College, Kanpur, Uttar Pradesh, over a period of 3 years from July 2017 to June 2020. The samples collected were screened by enzyme-linked immunosorbent assay (ELISA) tests. RESULTS A total of 69561 blood units were collected during this 3-year study from July 2017 to June 2020. Of all the blood bags screened, the highest prevalence was seen for HBV followed by HCV and HIV. 949 (1.4 %) were reactive for HBV, 75 (0.1 %) were reactive for HIV and 332 (0.5 %) were reactive for HCV. The results show a remarkable increase in the seropositivity for hepatitis C infection. CONCLUSIONS The seroprevalence of HCV has seen an increase in case load over the years as compared to HBV and HIV. This increase in case volume is indicative of impending liver diseases progressing to chronic stage over the years. Thus, it is imperative to create awareness in the general population to help reduce the risk factors responsible for HCV infection. KEYWORDS Blood Transfusion, Voluntary Donors, HCV, HBV, HIV, Seroprevalence, Transfusion Transmitted Infections (TTI’s)

scholarly journals Prevalence of hepatitis B and C among patients admitted in respiratory medicine ward of a tertiary care hospital in Mullana, Ambala, Haryana, India

2017 ◽  
Vol 5 (4) ◽  
pp. 1546 ◽  
Author(s):  
Ankit Sharma ◽  
Sameer Singhal ◽  
Dinesh Mehta ◽  
Abinav Dagar
Keyword(s):  
Public Health ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Tertiary Care ◽  
Respiratory Medicine ◽  
World Population ◽  
Major Public Health Problem ◽  
Care Hospital ◽  
Prevalence Rates ◽  
High Prevalence

Background: Viral Hepatitis B and C have become a major public health problem. Hepatitis B affects approximately 30% of world population or about 2 billion people have serological evidence of either current or past infection. Hepatitis C virus infects approximately 3% of world population placing about 170 million people at risk of liver disease. In India, HBsAg prevalence rates among general population ranges from 0.1% to 11.7%, being 2% to 8% in most studies and seroprevalence for Hepatitis C ranges from 0.1% to 8% among general population.Methods: The study was conducted in the respiratory medicine Ward, MMIMSR in the month of August 2016. 200 patients were taken up for the study after clinical examination, necessary investigation and proper consent. Patients were tested for HBsAg antigen and HCV Tridot. Patients were put through a carefully designed questionnaire to look for possible cause of infection. Patients who came out to be positive for either Hepatitis B or C were counselled about further investigations and treatment options.Results: The prevalence rate for Hepatitis B came out to be 9% and for Hepatitis C was 5.5%. Hepatitis has become a major public health issue in India particularly in the rural areas. High prevalence rates among patients with respiratory diseases can be attributed to unsafe therapeutic injections and use of shared needles.Conclusions: There is a need to carry out larger studies to better elucidate the epidemiology of Hepatitis B and C and to identify high prevalence areas and simultaneously focus on improving public health measures to prevent disease transmission and decrease the burden of disease.

scholarly journals To Evaluate the Frequency of Diabetes Mellitus Patients with Hepatitis C at Tertiary Hospital of Sindh, Pakistan

2021 ◽  
pp. 34-38
Author(s):  
Kuldeep Kumar Mewaram ◽  
Faraz Qurban Rajper ◽  
Khalida Unar ◽  
Mirza Tasawar Baig ◽  
Mirza Tasawar Baig ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hepatitis C ◽  
Nucleic Acid ◽  
Sample Size ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Major Theme ◽  
Care Hospital ◽  
Age Group

Objective: The major theme of the research was to evaluate the frequency of diabetes mellitus patients with hepatitis C infection at tertiary care hospital of Sindh, Pakistan. Methodology: Descriptive cross sectional study was conducted at tertiary care hospital of Sindh, Pakistan for the period of 08 months; total 374 sample size was calculated by using Rao soft sample size calculator at the prevalence rate of 58.3% and confidence level 95% and margin of error 5%. Data was collected from patients of sero-positive HCV-RNA (Hepatitis C Virus-Ribose Nucleic Acid) visiting outpatient department or admitted at tertiary care hospital of Sindh, Pakistan and Informed consent form was also filled from all included subjects and data was analyzed by using SPSS software version 24.00. Results: From the 374 patients 209 were males and 165 females and all participants were divided in to various age groups as 15 patients were in the age group of 20-25 years, 67 patients were in 26-30 years, 48 patients included in 31-35 years and 109 patients were included in to age group of 36-40 years. Only 12 patients were included in the age group of 50 years and above. Total 164 (43.85%) were diabetic and 229 (61.22%) were diagnosed with Hepatitis C RNA (Ribose Nucleic Acid) positive. Patients had various range of HbA1c as 93 patients had range between 6-7mmol/dl. 107(28.60%) included in 7-9mmol/dl, 145(38.77%) included in 9-11mmol/dl and only 29 patients were having HbA1c (Glycated Hemoglobin) level above 11mmol/dl. Conclusion: It was concluded that there were increased number of diabetic patients with hepatitis C in worsening condition, so the proper programs should be conducted in order to reduce the complication of co-morbid disease.

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