scholarly journals A Cross-Sectional Study of Clinical and Immunological Profile of SLE Patients from a Tertiary Care Center in the Sub Himalayan Region of Northern India

2021 ◽  
Vol 6 (3) ◽  
pp. 57-61
Author(s):  
Varun Jaswal ◽  
Jitender K Mokta ◽  
Vivek Chauhan
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Age Group ◽  
Tertiary Care Center ◽  
Cross Sectional ◽  
Northern India ◽  
Immunological Profile ◽  
Reproductive Age Group

Introduction: Systemic Lupus Erythematosus (SLE) is a disease of thousand faces whose manifestations vary with the interplay of genetic, ethnic, and host factors along with environmental exposures and geographical conditions. Since the first case of SLE reported in India in 1955, many case series have been published from various centers depicting Clinical and Immunological features in the Indian population. This study was undertaken to study the clinical and immunological profile in a tertiary care center in the sub-Himalayan region of northern India. Materials and Methods: This study is a cross-sectional retrospective study conducted at a tertiary care center in the hilly northern state of Himachal Pradesh over a period of 1 year; from 1st June 2017 to 31st May 2018. The records of all patients admitted in the study period with the department of medicine and diagnosed with SLICC 2012 classification criteria were studied to abstract the Clinical and Immunological profile of patients. Results: A total of sixty-nine patients were included in the study. 96% of the subjects were female patients, and 84 % of the patients were in the reproductive age group of 20 – 40 years. Mucocutaneous manifestations were most commonly seen in nearly 89 % of patients followed by musculoskeletal involvement in about 71 %. Hematological involvement was more frequent than reported in the literature. Lupus Nephritis was diagnosed in about 30 % of the patients. Fatigue and synovitis were the most common features, followed by oral ulcers and Acute cutaneous lupus. ANA and ds DNA positivity was 98.5 and 72.4 % respectively. Six cases of MCTD were d=found in the study group. Conclusion: In hospitalized SLE patients admitted in a tertiary care center of the northern hilly state, females of reproductive age group constituted the majority of patients. Mucocutaneous, Musculoskeletal, hematological, and renal involvement was most prevalent. Keywords: SLE, cross-sectional study, Mucocutaneous involvement, Renal Biopsy, Hilly area.

scholarly journals Knowledge, attitude and experiences of menopause in the postmenopausal women at a tertiary care center: a cross sectional study

2018 ◽  
Vol 7 (11) ◽  
pp. 4758
Author(s):  
Shivraj More ◽  
Sujatha P. ◽  
Karthiga Karthiga
Keyword(s):  
Postmenopausal Women ◽  
Care Center ◽  
Tertiary Care ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Government

Background: Menopause is an inevitable milestone in the reproductive life of every woman. The objective is to investigate menopausal knowledge, attitude, symptoms and management among the participants, to identify the differences according to their educational status and to examine correlations of knowledge, attitude and symptoms pertaining to menopause.Methods: This cross-sectional study was conducted for a period of 10 months in postmenopausal women attending a tertiary care center in Pondicherry, India with a structured questionnaire developed on the basis of the objective of the study.Results: 330 postmenopausal women were recruited, and all were aware of their postmenopausal status. Mean age at menopause was 45.91±2.66 years. 54.5% were aware about what menopause was while 5.5% were unaware. 12.1% had proper knowledge about cause of menopause, whereas 3.6% said it is due to god’s decision / turning point. Most prevalent symptoms were tiredness (89.6%) followed by vasomotor symptoms like hot flushes (88.5%) and night sweats (80.3%). Only 2.1% had used HRT for menopausal symptoms.Conclusions: Depth of knowledge is more important when concern is about greater health disrupter which tends to be imperceptible for a long time such as bone health and cardiovascular risk profile. Thus, the government could concentrate on providing health services to women in post reproductive age group also besides women in the reproductive age.

scholarly journals Self-medication among pregnant women attending antenatal clinic at Tertiary Care Center of Nepal

2020 ◽  
Vol 8 (2) ◽  
pp. 5-10
Author(s):  
Ajit Kumar Sah ◽  
Anish Giri ◽  
Anjan Palikhey ◽  
Roshan Kumar Chaurasiya ◽  
Sudeep Kumar Yadav
Keyword(s):  
Pregnant Women ◽  
Care Center ◽  
Tertiary Care ◽  
Antenatal Clinic ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Tertiary Care Center ◽  
Self Medication ◽  
Cross Sectional ◽  
Tract Infections

Background and Objectives: Self-medication can cause significant challenges for the individuals and community, especially in women during pregnancy. The aim of this study was to evaluate the prevalence of self-medication among the pregnant women attending antenatal clinic in a tertiary care center of Nepal. Material and Methods: In this cross-sectional study, a total of 225 pregnant women were evaluated for the prevalence of self-medication during pregnancy. Descriptive statistics and chi-square tests were used for statistical analysis of data. Results: The results showed that the prevalence of self-medication, in pregnant women was 41.3%. The leading illness/ symptoms which led to self-medication among pregnant women attending clinic were to relieve headaches 29 (31.2%), cough 21 (22.6%), vomiting 13 (14%), treat fever 11 (11.8%), urinary tract infections 11 (11.8%) and drugs commonly reported for self-medication were paracetamol (30.10%), cough remedies (19.30%), antiemetics (16.13%), analgesics (10.75%). Conclusion: Prevalence of self-medication among pregnant women is high in Nepal. This is a threat to the safety of the developing foetus and the pregnant woman. Therefore, it seems necessary to provide public trainings for all women of reproductive age and train them about the dangers and side effects of self-medication.

scholarly journals A cross sectional study on antipsychotic induced amenorrhoea in women attending a tertiary care centre in South India

2019 ◽  
Vol 7 (6) ◽  
pp. 2067
Author(s):  
Monisha Kanya Savarimuthu ◽  
Srisudha Bhaskar ◽  
Anu Mary Alexander ◽  
Suja Kurian
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Antipsychotic Treatment ◽  
Age Group ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Menstrual Cycles ◽  
Reproductive Age Group

Background: Absence of menstrual period in a woman of reproductive age group could be physiological or pathological. Ascertaining the cause for this is a common clinical scenario faced by physicians. It is also a common clinical problem in women who are on treatment with antipsychotic medication. This cross-sectional study aimed to assess the occurrence of antipsychotic induced amenorrhoea among women aged 18-45 years, attending outpatient services of a tertiary care setting, the factors associated and to assess the effective strategies of treatment.Methods: Retrospective chart review of clinical details of women in the reproductive age group who fulfilled the inclusion criteria was carried out. They were divided into two groups: Group A included 84 women with antipsychotic induced amenorrhea and Group B included 94 women on antipsychotics and had normal menstrual cycles. Various factors and strategies which worsened or alleviated the symptoms were noted.Results: Women who were less than 35 years of age, on antipsychotic treatment for more than two years duration (52;83.9%) and those who were on treatment with Risperidone (69;73.4%) were identified as having the risk of developing antipsychotic induced amenorrhoea. The strategy of switch of medication to prolactin sparing antipsychotic was more effective in regularising the menstrual cycles (43;87.8%).Conclusions: In women presenting with amenorrhoea, a possible medication induced aetiology need to be considered, especially use of antipsychotics. Further understanding of the complexities of this relationship may help to guide the assessment and proper treatment of women with antipsychotic related amenorrhoea.

scholarly journals Hypocalcemia in Elderly Population in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Sangita Thapa ◽  
Rabindra Jang Rayamajhi
Keyword(s):  
Serum Calcium ◽  
Elderly Population ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional

Introduction: As the medical facilities are improving, the life expectancy is increasing which has led to rapid rise in elderly population. The epidemiology of many diseases in elderly has been modified, including calcium imbalance. This study aims to know the prevalence of hypocalcemia in elderly population visiting a tertiary care center of Kathmandu. Methods: A descriptive cross-sectional study was conducted in a tertiary care center of Kathmandu from March to July 2020 after obtaining ethical clearance (Ref: 2003202007). Total 402 participants at or above 60 years of age groups visiting outpatient departments were included in the study by convenience sampling method excluding those under vitamin D and calcium supplements. Serum total calcium level was measured using standard routine method and corrected with albumin. The serum calcium value less than 8 mg/dl was considered as hypocalcemia in accordance with the reference range of our laboratory. Data analysis for calculation of frequency and proportion was done in Statistical Package of Social Sciences. Results: The prevalence of hypocalcaemia in elderly was found to be 97 (24.1%). Out of 286 participants of age group 60-74 years, hypocalcemia was seen in 75 (26.2%) and among 116 participants of age group >74 years, 22 (19%) were hypocalcemic. Among 181 male participants, 44 (24.3%) had hypocalcemia and out of 221 female participants, 53 (24%) had hypocalcemia. Conclusions: The finding of present study suggests that hypocalcemia is common among elderly which can be life threatening. Therefore, regular monitoring of serum calcium is recommended for this age group.

scholarly journals Orthopedic Implant Removal in the Department of Orthopedics of a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Ravi Bhandari ◽  
Pravakar Dawadi ◽  
Mohit Thapa Magar ◽  
Ritesh Sinha ◽  
Nirab Kayastha ◽  
...  
Keyword(s):  
Surgical Procedures ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Implant Removal ◽  
Orthopedic Implant ◽  
Age Group ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional

Introduction: Implant removal surgery is one of the common surgical procedures done in orthopedics. Studies report that a major portion of orthopedic surgeries carried out in different institutions comprises implant removal procedures. This can be challenging in limited manpower and infrastructure availability scenarios, like in developing countries like Nepal. This study aims to study the prevalence of orthopedic implant removal procedures carried out among overall surgical procedures in the orthopedic department of a tertiary care center in Nepal. Methods: A descriptive cross-sectional study was performed on the medical records of the department of orthopedics of a tertiary care center after approval from the institutional review committee. The data included records from the starting of 2018 to the end of 2019. Data related to the number of implant removal procedures, types of implants, indications, fracture sites, anesthesia use, gender and age distribution were studied. Statistical Package for Social Sciences version 20 was used to study descriptive data. Results: Out of 2557 orthopedic operations carried out in the study duration, 458 (17.91%) of implant removal procedures were done in the department. The most common age group was the young adult age group, 255 (55.68%). Medium-sized implants were the commonly removed ones, 337 (73.58%). Elective procedures were the most common indication, 369 (80.57%). Conclusions: Implant removal procedures cover a major fraction of overall orthopedic operations carried out by the department, most of which are elective procedures. In limited-resource settings, this can be challenging, and a proper evaluation with counseling could be done before implant removal surgery.

scholarly journals Surgical Emergencies among Gynecological Surgeries in a Tertiary Care Center: a Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Indira Acharya ◽  
Sumana Thapa
Keyword(s):  
Ectopic Pregnancy ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Age Group ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional ◽  
Gynecology And Obstetrics ◽  
Surgical Emergencies

Introduction: The management of gynecological emergencies is essential for the preservation of the life of affected woman, her sexual functions and fertility particularly in disease conditions that threaten her life. The main objective of the study is to determine the proportion of the surgical emergencies among gynecological surgeries in a tertiary care center. Methods: This is a descriptive cross-sectional study conducted in the department of gynecology and obstetrics in Shree Birendra Hospital, Kathmandu, Nepal from April 2013 till March 2017. Ethical approval was taken from the Institutional Review Committee (IRC) in November 2019. This study was conducted among 515 gynecological surgeries by using convenience sampling methods. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Data were analyzed using EXCEL software. Results: In our study, the proportion of surgical emergencies among total gynecological surgeries performed in the department of gynecology and obstetrics in Shree Birendra Hospital was 120 (23.30%). The highest number of surgical emergencies was observed in the age group of 20-29 years old, followed by less than 19 years of old age group. Ectopic pregnancy accounting for 85 (70.83%) is found to be the most common surgical emergencies in our study. Out of all surgical emergency cases, most of them underwent salpingectomy 65 (54.16%) followed by salpingectomy with tubal ligation 20 (16.16%). Conclusions: Surgical emergencies among gynecological surgeries are found to be in greater proportion in the department of gynecology and obstetrics in Shree Birendra Hospital. Ectopic pregnancy accounted for more than half of the diagnoses in this study.

scholarly journals Metabolic syndrome in alopecia areata: an observational study at a tertiary care center

2021 ◽  
Vol 7 (5) ◽  
pp. 647
Author(s):  
Subrata Kumar Das ◽  
Saptadipa Das
Keyword(s):  
Metabolic Syndrome ◽  
Observational Study ◽  
Alopecia Areata ◽  
Care Center ◽  
Tertiary Care ◽  
Age Group ◽  
Tertiary Care Center ◽  
Cross Sectional ◽  
Laboratory Parameters ◽  
Number Of Patients

<p class="abstract"><strong>Background:</strong> The aim was to evaluate the parameters of metabolic syndrome (MS) in patients of alopecia areata and to investigate the possibility of an existing relationship between MS and alopecia areata (AA).</p><p class="abstract"><strong>Methods:</strong> This cross-sectional observational study included 50 patients with AA who attended OPD of department of dermatology at a tertiary care center during a period of 1 year. Clinical and laboratory parameters were noted in each patient.<strong></strong></p><p class="abstract"><strong>Results:</strong> This study included 50 patients with AA (33 males and 17 females). In the present study maximum number of patients belonged to the age group 20-30 years with 23 patients, followed by 30-40 years with 17  patients. Most of the study subjects, 17 were college students and number of employees were 15. Out of 50 patients 44  had patch(es) and 2 patient had alopecia totalis. In this study out of 50 patients, 38 had mild AA, 7 had AA and 5 patients had severe AA. No significant derangement of clinical and laboratory parameters of MS observed in patients of AA.</p><p class="abstract"><strong>Conclusions:</strong> In the present study we did not observe any significant derangement of clinical and laboratory parameters of  MS  in patients of alopecia areata.</p>

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