scholarly journals Cutaneous manifestations in COVID-19 patients in a district COVID care centre

2021 ◽  
Vol 7 (6) ◽  
pp. 805
Author(s):  
Prathyusha Dasari ◽  
Swetha A. Chowdary ◽  
Haritha Samanthula ◽  
Soumya Ruvva
Keyword(s):  
Case Reports ◽  
Severe Disease ◽  
Respiratory Illness ◽  
Maculopapular Rash ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Skin Manifestations ◽  
Indian Scenario

<p class="abstract"><strong>Background:</strong> COVID-19, initially started as respiratory illness and evolved to involve various systems. Skin has been the least targeted organ with manifestations limited to case reports and series in a foreign scenario. Here, we tried to understand a same in an Indian scenario.</p><p class="abstract"><strong>Methods:</strong> This was cross-sectional study done in district COVID centre among patients with a confirmed diagnosis of COVID-19 with cutaneous manifestations for 3 months. A detailed history, complete cutaneous examination was carried out. Timing in relation to other symptoms and severity was assessed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Among the 1603 patients, 39 (2.4%) had skin manifestations. Urticaria (20.5%), petechiae/purpura (17.9%), pruritis (15.4%) were the most common followed by maculo-papular rash (7.7%), manifestations secondary to drugs (7.7%), diffuse hair fall (7.7%), pseudo-chilblains (5.1%), vesicular eruptions (5.1%), infections (5.1%), cellulitis, gangrene and livedoid vasculitis. Timing of skin lesions ranged from 2 days before (10.3%) onset of COVID-19 symptoms or diagnosis to 10 days after (69.2%). Urticaria, petechiae, maculopapular rash were seen more commonly in patients with fever and respiratory symptoms. Asymptomatic cases showed urticaria, petechiae and pseudo-chilblains. Majority were in mild and moderate disease and livedoid vasculitis patient had severe disease.</p><p class="abstract"><strong>Conclusions:</strong> Skin manifestations in COVID-19 are relatively uncommon in Indian scenario. However, few of the manifestations give a hint of infection while some correlate with the severity of disease.</p>

scholarly journals Dermatological Manifestation in Coronavirus Disease 2019 Patients in Iraq

2021 ◽  
Vol 9 (B) ◽  
pp. 1085-1091
Author(s):  
Anfal L. Al-Harbawi ◽  
Qasim S. Al Chalabi ◽  
Hala N. Alsalman ◽  
Mohammad S. Saeed
Keyword(s):  
Early Recognition ◽  
Cutaneous Lesion ◽  
Maculopapular Rash ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Prodromal Phase ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
High Incidence ◽  
Common Skin

Background: Coronavirus disease-19 (COVID-19) is a growing pandemic around the globe that was initially discovered in Wuhan in December 2019. Despite the relatively high incidence of cutaneous manifestations in COVID-19, their role in early recognition and disease progression has not been fully investigated. Aim of this study: To report the possible incidence of the cutaneous lesion in COVID 19 patients and to describe various cutaneous manifestations and their correlation with other clinical features in Covid-19 positive patients to facilitate diagnosis and prognostications toward this virus. Methods: This research was conducted as a cross-sectional study. Skin lesions photography and their analysis were collected by dermatologists from 18 cities in Iraq between September 2020 to January 2021. The data were processed using statistical package SPSS version 23. Results: A total of 3117 confirmed COVID-19 cases were included in this study. Around 268 patients developed skin lesions with age ranged between 8 to 84 years. Of these skin lesions, 46.2% developed during the illness with minority erupting during the prodromal phase, whilst 38.8% appeared after hospitalization. The most common skin lesion was in the form of urticarial 36.74% followed by herpetic lesions 28.4%, maculopapular rash 11.74% and the remainder being candidiasis, oral thrush, chilblains, and other skin conditions. The most affected area was the torso (46%) followed by limbs, face, fingers, and toes. Conclusion: This study demonstrated the high incidence rate of dermatological lesions in different phases of COVID-19 with urticarial rash being the most frequent clinical pattern.  

scholarly journals Skin Manifestations in COVID-19 Patients: Are They Indicators for Disease Severity? A Systematic Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Parnian Jamshidi ◽  
Bahareh Hajikhani ◽  
Mehdi Mirsaeidi ◽  
Hassan Vahidnezhad ◽  
Masoud Dadashi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mortality Rate ◽  
Disease Severity ◽  
Severe Disease ◽  
Maculopapular Rash ◽  
Skin Lesions ◽  
Vascular Lesions ◽  
Cutaneous Manifestations ◽  
Skin Manifestations ◽  
Severity Of The Disease

Introduction: Until now, there are several reports on cutaneous manifestations in COVID-19 patients. However, the link between skin manifestations and the severity of the disease remains debatable. We conducted a systematic review to evaluate the temporal relationship between different types of skin lesions and the severity of COVID-19.Methods: A systematic search was conducted for relevant studies published between January and July 2020 using Pubmed/Medline, Embase, and Web of knowledge. The following keywords were used: “SARS-CoV-2” or “COVID-19” or “new coronavirus” or “Wuhan Coronavirus” or “coronavirus disease 2019” and “skin disease” or “skin manifestation” or “cutaneous manifestation.”Results: Out of 381 articles, 47 meet the inclusion criteria and a total of 1,847 patients with confirmed COVID-19 were examined. The overall frequency of cutaneous manifestations in COVID-19 patients was 5.95%. The maculopapular rash was the main reported skin involvement (37.3%) commonly occurred in middle-aged females with intermediate severity of the disease. Forty-eight percentage of the patients had a mild, 32% a moderate, and 20% a severe COVID-19 disease. The mild disease was mainly correlated with chilblain-like and urticaria-like lesions and patients with vascular lesions experienced a more severe disease. Seventy-two percentage of patients with chilblain-like lesions improved without any medication. The overall mortality rate was 4.5%. Patients with vascular lesions had the highest mortality rate (18.2%) and patients with urticaria-like lesions had the lowest mortality rate (2.2%).Conclusion: The mere occurrence of skin manifestations in COVID-19 patients is not an indicator for the disease severity, and it highly depends on the type of skin lesions. Chilblain-like and vascular lesions are the ends of a spectrum in which from chilblain-like to vascular lesions, the severity of the disease increases, and the patient's prognosis worsens. Those with vascular lesions should also be considered as high-priority patients for further medical care.

scholarly journals Dermoscopy and Trichoscopy in Dermatomyositis—A Cross-Sectional Study

2022 ◽  
Vol 11 (2) ◽  
pp. 375
Author(s):  
Magdalena Żychowska ◽  
Adam Reich
Keyword(s):  
Diagnostic Technique ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Cutaneous Lesions ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Non Invasive ◽  
Inflammatory Dermatoses ◽  
Curved Vessels ◽  
Established Role

Background: (Video)dermoscopy is a non-invasive diagnostic technique that has a well-established role in dermatooncology. In recent years, this method has also been increasingly used in the assessment of inflammatory dermatoses. So far, little is known about the (video)dermoscopic features of dermatomyositis (DM). Methods: Consecutive patients with DM were included in the study and videodermoscopic assessments of the nailfolds, scalp, and active skin lesions were performed. Results: Fifteen patients with DM (10 women and 5 men) were included. Capillaroscopy showed elongated capillaries (90.9%), avascular areas (81.8%), disorganized vessel architecture (81.8%), tortuous capillaries (72.7%), dilated capillaries (72.7%), and hemorrhages (72.7%). The trichoscopic findings included linear branched vessels (80.0%), linear vessels (60.0%), linear curved vessels (53.3%), perifollicular pigmentation (40.0%), perifollicular erythema (33.3%), scaling (20.0%), white (20.0%) or yellow (20%) interfollicular scales, and white (20.0%) or pinkish (13.3%) structureless areas. Polymorphic vessels of an unspecific distribution and white or pink structureless areas were frequently observed under dermoscopy in cutaneous manifestations of DM, including Gottron’s papules and Gottron’s sign. Conclusions: Dermoscopy of the nailfolds (capillaroscopy), scalp (tricoscopy), and active cutaneous lesions may be of value in the preliminary diagnosis of DM.

scholarly journals Conjunctivitis and other ocular findings in patients with COVID-19 infection

2021 ◽  
Vol 41 (5) ◽  
pp. 280-284
Author(s):  
Haider Aswad Layikh ◽  
Zainab Adel Hashim ◽  
Alyaa A. Kadum
Keyword(s):  
Viral Infection ◽  
Care Center ◽  
Severe Disease ◽  
Respiratory Illness ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Ocular Findings ◽  
Standard Deviation Range ◽  
Severity Of The Disease ◽  
Novel Coronavirus

BACKGROUND: COVID-19 is an acute respiratory illness caused by a novel coronavirus (SARS-CoV-2). COVID-19 that might affect the eye in the form of conjunctivitis and other ocular features. OBJECTIVES: Assess the frequency and clinical profile of conjunctivitis and other ocular findings in Iraqi patients with confirmed COVID-19 infection. DESIGN: Analytical cross-sectional study. SETTING: Secondary care center. PATIENTS AND METHODS: This study involved patients diagnosed with SARS-CoV-2 viral infection of variable disease severity from June 2020 to December 2020. Ocular history and the severity of SARS-CoV-2 viral infection was assessed for all of the patients. MAIN OUTCOME MEASURES: Frequency of conjunctival inflammation and other ocular findings in patients with coronavirus infection. SAMPLE SIZE: 186 patients. RESULTS: The patients had a mean (standard deviation, range) age of 44.4 (18.8, 18–78) years. Conjunctivitis was present in 25 patients (13.4%). There was no significant association between prevalence of conjunctivitis and patient gender ( P =.868). However, conjunctivitis was significantly associated with the severity of the disease ( P =.018): the rate of conjunctivitis was significantly higher in cases with severe disease (28%) in comparison with those with mild to moderate clinical presentation (9.3%). The natural course of conjunctivitis seemed to be mild with no effect on visual acuity and no short-term complications. CONCLUSION: Conjunctivitis can occur in patients with SARS-CoV-2 viral infection, and could be a presenting sign. Conjunctivitis is more common in cases of severe COVID-19 infection and since it could be a presenting sign it might be of benefit in the early diagnosis and treatment of COVID-19. LIMITATION: Single-center study, safety limitations in the examination of the patients. CONFLICT OF INTEREST: None.

scholarly journals Cutaneous manifestations of chronic alcoholism: a cross sectional study in a tertiary care centre in South India

2016 ◽  
Vol 2 (4) ◽  
pp. 55
Author(s):  
Kumara Lakshmanan Sengotuven ◽  
Rangaraj Murugaiyan ◽  
Karthikeyan Kaliaperumal
Keyword(s):  
Tertiary Care ◽  
Chronic Alcoholism ◽  
Cross Sectional Study ◽  
Alcohol Dependency ◽  
Care Centre ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Skin Manifestations

<p class="abstract"><strong>Background:</strong> Alcoholism is a chronic fatal disease of worldwide concern. Alcohol abuse can present in a variety of ways, and dermatological disease is emerging as an important marker of alcohol misuse. The aim is to find out the various skin manifestations associated in chronic alcoholics, to find out the most common skin manifestations among chronic alcoholics and to identify the early skin changes in chronic alcoholics.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study conducted in patients attending medicine, psychiatry and dermatology clinics at a tertiary care centre, Puducherry. Inclusion criteria were patients with history of chronic alcoholism, aged above 18 years. After obtaining history, cutaneous examination was done including skin, mucosa, hairs, and nails. Alcohol dependency pattern was calculated using short alcohol dependency score (SADD).<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 130 patients were included. All were male and 59.2% of them belonged to high dependency pattern. About 128 of them had dermatological manifestations pityriasis versicolor was the most common dermatoses followed by psoriasis. Alcohol specific dermatoses were not seen in our study.</p><p><strong>Conclusions:</strong> In our study, 98.4% of alcoholics had skin manifestations, of which cutaneous infections were the most common. </p>

Emergency Consultations in Dermatology in a Secondary Referral Hospital in Southern Switzerland: A Prospective Cross-Sectional Analysis

Dermatology ◽  
2019 ◽  
Vol 235 (3) ◽  
pp. 243-249 ◽  
Author(s):  
Lorenzo Pelloni ◽  
Simone Cazzaniga ◽  
Luigi Naldi ◽  
Luca Borradori ◽  
Carlo Mainetti
Keyword(s):  
Skin Lesions ◽  
Cross Sectional Study ◽  
Referral Hospital ◽  
Cross Sectional ◽  
Emergency Visits ◽  
Duration Of Symptoms ◽  
Cutaneous Manifestations ◽  
Emergency Visit ◽  
Cutaneous Problem ◽  
Malignant Skin

Background/Aims: The spectrum of dermatological emergencies is broad. Only a few studies have assessed the profile of dermatological conditions resulting in an emergency visit in a referral hospital. We sought to assess the conditions prompting an urgent dermatological visit and to compare the diagnoses with those made during the regular scheduled encounters. Methods: We performed a cross-sectional study of all patients with a cutaneous problem attending our emergency consultation during a 7-month period. The study variables were gender, age, duration of symptoms, diagnosis, need for hospitalization and/or follow-up. We further evaluated patients attending scheduled visits to compare the demographic characteristics and diagnoses between the two groups. Results: Six hundred fifty-two consecutive patients with an urgent dermatological consultation were included. Three hundred sixty (55.2%) were women and 292 (44.8%) were men. Infectious diseases (32.8%) as well as various forms of eczema (24.8%) constituted the most frequent causes for an emergency visit. Approximately 40% of emergency visits took place more than 1 week after the development of the cutaneous manifestations. The most frequent disorders seen in the 1,738 control patients included benign melanocytic and nonmelanocytic tumors (27.2%) and malignant skin lesions (11.5%). Conclusions: Our study indicates that the dermatological diagnoses in the emergency visits significantly differ from those of the routinely scheduled appointments. In a significant portion of patients, the use of an emergency consultation was not justified. This study provides support to the idea that a specific training is required to manage dermatological emergencies and that efforts should be made to reduce unjustified emergency visit use.

scholarly journals Frequency of cutaneous manifestations in drug abuse patients.

2021 ◽  
Vol 28 (04) ◽  
pp. 497-503
Author(s):  
Zahid Rafiq ◽  
Syed Muntazir Mehdi ◽  
Urfa Shafi
Keyword(s):  
Drug Abuse ◽  
Drug Addiction ◽  
Cross Sectional Study ◽  
Drug Abusers ◽  
Cross Sectional ◽  
Dermatology Department ◽  
Cutaneous Manifestations ◽  
Skin Changes ◽  
Skin Manifestations ◽  
Mucosal Changes

Objective: Drug abuse and drug addiction cases have been increased immensely in last few decades in Pakistan. This study was conducted to assess the frequency of cutaneous manifestations in drug abuse patients. Study Design: Cross Sectional study. Settings: Dermatology Department of a DHQ Teaching Hospital/Sahiwal Medical College, Sahiwal and Central Jail Hospital, Sahiwal. Period: November 2019 to June 2020. Material & Methods: 50 patients with drug abuse irrespective of age and gender were selected. Skin manifestations based on history and examination recorded on predesigned proforma. Laboratory investigations and skin biopsies were performed to confirm diagnoses in doubtful cases. Results: A total of 50 male patients with age above 16 years were enrolled. Single drug addiction was noticed in 62% (n=31) and polydrug abuse was observed in 38% (n=19). Regarding mode of drug intake, single and multiple modes of drug administration were seen in equal number 50% (n=25) each. Major bulk of skin manifestations were chronic including skin scars 66% (n=33), xerosis 60% (n=30), hyperpigmentation 58% (n=29), oral mucosal changes 94% (n=47) and facial skin changes 60% (n=30). Acute along with chronic skin changes were observed in 30% (n=15) mainly including injection marks 30% (n=15), vascular changes 12% (n=6) and infections 8% (n=4). Conclusion: Skin scars, xerosis, hyperpigmentation and oral mucosal changes are the common skin changes observed among drug abusers. Thus, physicians need to be aware of skin signs of drug abuse for timely recognition of substance abuse disorders and effective management.

scholarly journals Skin manifestations of hematologic malignancies

2016 ◽  
Vol 43 (3) ◽  
pp. 121-124 ◽  
Author(s):  
AKM Rejaul Haque ◽  
ASM Zakaria ◽  
Abida Sultana ◽  
Md Rafiquzzaman Khan
Keyword(s):  
Hematologic Malignancies ◽  
Skin Lesions ◽  
Gingival Hyperplasia ◽  
Cutaneous Lesions ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Skin Manifestations ◽  
Aleukemic Leukemia Cutis ◽  
Leukemia Cutis ◽  
One Year

Hematologic malignancies can present with various cutaneous manifestations. These include specific cutaneous diseases & non-specific cutaneous lesions. Non-specific skin lesions are more common in patients with hodgkins diseases. Generalized severe pruritus may precede other findings of Hodgkins disease by many months . So an evaluation for underlying lymphoma should be considered in patient with severe itching. Leukemia cutis (specific skin lesions of Leukemia) most commonly occurs concomitant with or following the diagnosis of leukemia. The skin may also be the site of relapse of leukemia after chemotherapy. Uncommonly leukemia cutis may be identified while the bone marrow & peripheral blood are normal. Those patients are classified as aleukemic leukemia cutis. This cross sectional observational study was carried out in the Hematology department of Bangabandhu Sheikh Mujib Medical University from January 2012 to January 2013 with the intention to know the prevalence of skin manifestations of hematologic malignancies & to help diagnose and manage hematologic malignancies in some extent. Total 127 consecutive patients who were already diagnosed as haematological malignancies & hospitalized were evaluated at the period of one year. Different types of cutaneous lesions were found in our study population, Infections were the highest number, 32(25.19%) patients suffering from various infections. Other findings includemalignant infiltration, 10(7.87%); hemorrhagic 121 lesions (petechia and ecchymosis), 17(13.38%); drug reaction, 5(3.93%); gingival hyperplasia, 3(2.36%); pruritus, 23(18.11%); pigmentation, 20(15.74%); prurigo, 8(6.29%) and ichthyosiform lesion, 19(14.96%).Bangladesh Med J. 2014 Sep; 43 (3): 121-124

scholarly journals Cutaneous Lesions in Iranian Neonates and Their Relationships with Maternal-Neonatal Factors: A Prospective Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Hossein Firouzi ◽  
Iman Jalalimehr ◽  
Zahra Ostadi ◽  
Siavash Rahimi
Keyword(s):  
Neonatal Period ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Common Source ◽  
Sectional Study ◽  
Cutaneous Lesions ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Therapeutic Procedures ◽  
Maternal Disease

Cutaneous lesions are common in the neonatal period and mostly physiological, transient, and self-limited; uncommonly, they are pathological and require treatment and cooperation between neonatologists and dermatologists. Particular conditions, like prematurity, can influence the onset, type, and evolution of cutaneous manifestations. Of the several articles in the literature about skin findings in newborns, only a few were performed in Iran. We aimed to investigate dermatological findings in a sample of neonates within the first three days of life and to evaluate the association between skin lesions and neonatal- or maternal-related variables. A total of 1202 newborns, hospitalized in the Department of Pediatrics of Imam Sajjad Hospital of Ramsar and Shahid Rajaee Hospital of Tonekabon, Iran, for two years, were examined. All skin findings were recorded, and information on neonatal and maternal variables was collected and analyzed to detect statistically significant associations. Skin lesions were present in 958 newborns (79.8%). The prevalence of milia, erythema toxicum, salmon patch, and Mongolian spots were 45.2%, 43%, 37.3%, and 37%, respectively. Natural vaginal delivery, use of medication, term gestation, and maternal disease were associated with a higher incidence of cutaneous lesions in neonates. Milia, erythema toxicum, Mongolian spots, and genital hyperpigmentation were seen more frequently in the male gender. Conversely, skin desquamation was seen more frequently in females. Among maternal diseases, gestational diabetes mellitus, urinary tract infection, preeclampsia, hypertension, psychiatric disorders, and uterine infection were associated with a higher prevalence of cutaneous lesions. Neonatal cutaneous lesions are a common source of concern in parents and inexperienced physicians. Therefore, prompt recognition of neonatal cutaneous lesions is essential in order to avoid unnecessary diagnostic and therapeutic procedures.

scholarly journals Cutaneous Manifestations of Diabetes Mellitus in a Tertiary Care Hospital in Bengaluru – A Cross Sectional Study

2021 ◽  
Vol 8 (19) ◽  
pp. 1352-1356
Author(s):  
Kavana K ◽  
Sharath Kumar B.C
Keyword(s):  
Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Cutaneous Manifestation ◽  
Research Centre ◽  
General Description ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Skin Manifestations

BACKGROUND “Skin is a mirror of internal diseases”. Diabetes mellitus (DM) is a metabolic disorder that needs considerations of many different specialities but the importance of dermatologist’s knowledge has not drawn much attention. As a result, we intend to study various cutaneous manifestation of diabetes mellitus. Prior to diagnosis of diabetes mellitus, patient may present with cutaneous manifestation. Thus, it can help in early diagnosis, management and prevention of complication and help in improvement of quality of life. METHODS This is a descriptive cross-sectional study. A total of 500 diabetic patients with cutaneous manifestations, who attended skin outpatient department (OPD) at Kempegowda Institute of Medical Sciences Hospital and Research Centre, Bengaluru, Karnataka, India, were evaluated. Detailed history was taken along with physical and mucocutaneous examination. Cutaneous manifestations, general description of diabetes mellitus like duration, type, and drug history as well as the demographic data were collected and analysed using descriptive statistics. RESULTS Among a total of 500 diabetes mellitus subjects, the most common cutaneous manifestations were infections (35 %) followed by pruritus (11 %). Among infections, tinea infections (48.29 %) were the most common followed by intertrigo (21 %). CONCLUSIONS The ignorance of skin manifestations in diabetes or improper treatment may worsen the condition. Early detection and treatment of common skin manifestations in diabetes will prevent further complications especially in cases of extensive tinea corporis, pruritus, psoriasis, lichen planus, macro and micro angiopathies, trophic ulcers etc. KEYWORDS Cutaneous manifestations, Diabetes mellitus

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