Isolated Plexiform Neurofibroma of the Nasal Tip - A Rare Case Report

2021 ◽  
Vol 8 (33) ◽  
pp. 3169-3171
Author(s):  
Subhadeep Chowdhury ◽  
Tithi Debnath
Keyword(s):  
Plexiform Neurofibroma ◽  
Skin Lesions ◽  
The Body ◽  
Neurogenic Tumour ◽  
Nasal Tip ◽  
Cosmetic Reason ◽  
Café Au Lait Spots ◽  
Rare Case Report ◽  
History Of ◽  
Similar Kind

A 28-year-old female patient presented at ENT OPD with complaints of a slowly growing mass over nasal tip since last 5 years. There were no complaints of pain, nasal obstruction, or epistaxis. There were no skin changes or ulceration over the swelling and sensation was preserved. There was no history of similar kind of swelling in other parts of the body. History of trauma or any form of surgical intervention were excluded. Family history was insignificant. The swelling did not respond to any medications. The patient attended for cosmetic reason solely. Clinical examination showed a soft non-tender 4 cm by 4 cm mass over nasal tip and supratip area. Mobility of the mass was restricted and fixed to the alar cartilages. There was no evidence of café au lait spots or any other skin lesions. Anterior rhinoscopy was unremarkable. Diagnostic nasal endoscopy was also performed but no abnormality was detected. CT scan showed non-specific infiltrative subcutaneous lesions. T1W MRI showed an ill-defined hypodense mass over the nasal tip which was abutting the alar cartilages which showed mild enhancement with contrast (figure 1). T2W MRI showed hyperintense and or hypodense central focus (target sign). FNAC was done and report was suggestive of neurogenic tumour, most probably neurofibroma.

scholarly journals A case of Trixacarus caviae mange in a guinea pig (Caviaporcellus)

2018 ◽  
Vol 53 (4) ◽  
pp. 352 ◽  
Author(s):  
M. PERRAKI (Μ. ΠΕΡΡΑΚΗ) ◽  
M. SARIDOMICHELAKIS (Μ. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ) ◽  
C. KOUTINAS (X. ΚΟΥΤΙΝΑΣ) ◽  
A. KOUTINAS (Α. ΚΟΥΤΙΝΑΣ) ◽  
M. PAPAZACHARIADOU (Μ. ΠΑΠΑΖΑΧΑΡΙΑΔΟΥ)
Keyword(s):  
Guinea Pig ◽  
Subcutaneous Administration ◽  
Skin Lesions ◽  
The Body ◽  
Cavia Porcellus ◽  
The Past ◽  
Superficial Skin ◽  
Animal Medicine ◽  
History Of ◽  
Pruritic Skin

A male, peruvian, 1.5-years old, guinea pig {Cavia porcellus) was admitted to the Clinic of Companion Animal Medicine with a history of intensively pruritic skin lesions lasting for the past two months. Physical examination disclosed hypotrichosis, erythema, hyperpigmentation, scales, crusts, ulcers and papules in a focal to diffuse pattern on both the dorsal and ventral aspects of the body trunk. Whenever the handling of the animal was attempted, it started vocalizing, cycling and rolling in a frenzy manner. Pruritic papules were also observed on some parts of the glabrous skin of the owner. The diagnosis of Trixacarus caviae mange was based on the observation of the parasite in superficial skin scrapings. The subcutaneous administration of three weekly ivermectin injections, at the dose of 0.4 mg/Kg BW, resulted in the disappearance of the lesions and pruritus within a six-week period.

scholarly journals A clinical study on linear dermatoses at a teriary care teaching hospital in Davangere

2021 ◽  
Vol 7 (2) ◽  
pp. 201
Author(s):  
Sowmya Manangi ◽  
Anirudh M. ◽  
Aishwarya Sivuni ◽  
Hosalli Smrutha ◽  
Suga Reddy
Keyword(s):  
Lichen Planus ◽  
Skin Lesions ◽  
Epidermal Nevus ◽  
Linear Lesions ◽  
Cosmetic Reason ◽  
Histopathological Correlation ◽  
Lichen Striatus ◽  
History Of Disease ◽  
History Of ◽  
Blaschko’S Lines

<p class="abstract"><strong>Background:</strong> Skin lesions present with innumerable patterns like discoid, petaloid, arcuate, annular, polycyclic, livedo, reticulate, target, stellate, digitate, linear, serpiginous and whorled. Most of the linear lesions follow the Blaschko’s lines. Aim was to study the incidence of linear dermatoses, the age and sex incidence, various types of clinical presentation, various sites of distribution and their clinical correlation.  </p><p class="abstract"><strong>Methods:</strong> Detailed history including family history, History of disease documented with clinical examination. After counselling and after recording their consent for the test, skin biopsy along with routine investigations was done wherever needed and the results were evaluated. <strong></strong></p><p class="abstract"><strong>Results:</strong> Lichen striatus was seen in 29.91% followed by linear herpes zoster in 24.7%, linear lichen planus in 18.22%, linear verrucous epidermal nevus in 14.01%, segmental vitiligo in 3.73%, nevus depigmentation in 2.33% and others. Maximal cases were asymptomatic and reported for cosmetic reason. Intense itching was the main reason to bring the lichen planus patients and few cases of the lichen striatus patients for treatment.  </p><p class="abstract"><strong>Conclusions:</strong> Lichen striatus was found to be more common, female preponderance. Majority of patients showed unilateral distribution more on the extremities. Histopathological correlation shows the importance of histopathology which ultimately changes the management in any given condition.</p><p> </p>

scholarly journals Co-infection of mucormycosis and aspergillosis in post COVID-19 patient: A concerning rare case report during second wave of COVID-19 pandemic

2021 ◽  
Vol 7 (4) ◽  
pp. 300-303
Author(s):  
Anupam Das ◽  
Vikramjeet Singh ◽  
Nikhil Gupta ◽  
Ashish Chandra Agarwal ◽  
Tushar Gautam ◽  
...  
Keyword(s):  
Case Fatality ◽  
Invasive Disease ◽  
The Body ◽  
Sample Treatment ◽  
New Wave ◽  
Over The Counter ◽  
Uncontrolled Diabetes ◽  
Rare Case Report ◽  
Immunosuppressed Patients ◽  
History Of

COVID-19 manifestations have been evolving and affect different parts of the body every time a new wave comes. Association of mucormycosis in COVID-19, Covid Associated Mucormycosis (CAM) affected patients especially affecting paranasal sinuses must be given serious and timely consideration. Prolonged history of uncontrolled diabetes and over the counter use of steroids and abrupt stoppage of steroids are two main factors aggravating the illness, and both these factors must be critically checked. Clinical condition like Mucormycosis are caused by pathogenic moulds of family Mucorales and Aspergillosis is caused by Aspergillus species and both can cause an invasive disease with high case fatality rate, especially in immunosuppressed patients. In the present study we are discussing a case of co-infection in Post COVID-19 patient affected with mucormycosis and aspergillosis. A 55-year-old male patient with Type 2 diabetes mellitus presented post covid with ptosis and diplopia. Mixed infections of Rhizopus arrhizus and Aspergillus flavus were diagnosed by means of fungal microscopy and culture from biopsy sample. Treatment with Amphotericin B was started, the patient responded clinically within 15 days.

scholarly journals Paediatric Extensive Cervical Plexiform Neurofibroma Mimicking a Parotid Lesion

2020 ◽  
Vol 26 (2) ◽  
pp. 60-67
Author(s):  
Iu Tong Lim ◽  
Avatar Singh Mohan Singh ◽  
Viji Ramasamy ◽  
Suhana Abdul Rahim ◽  
Piao Piao Ang ◽  
...  
Keyword(s):  
Genetic Disorder ◽  
Plexiform Neurofibroma ◽  
Neurofibromatosis Type ◽  
Café Au Lait Spots ◽  
Left Neck ◽  
History Of ◽  
One Year ◽  
Important Variant ◽  
Carotid Space

Neurofibromatosis Type 1 (NF1), also known as von Recklinghausen’s disease is a multisystem genetic disorder that occurs with an incidence of 1 in 4000 live births. Plexiform nmeurofibroma (PN) is a rare important variant of NF1, seen in 5 to 15% of cases. We report a 7-year-old boy, without family history of neurofibromatosis presented with left neck swelling associated with multiple café au lait spots for one-year duration. Computed tomography of head and neck revealed an extensive soft tissue lesion involving the left parapharyngeal, carotid space and parotid space encasing the left internal and common carotid artery until its origin at the arch of aorta with erosion of the basiocciput. He underwent transcervical excision of the lesion, which was confirmed histopathologically as PN.

scholarly journals Case Report: A rapidly growing cyst on the scalp

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 779
Author(s):  
Emma Short ◽  
Aisling O'Shea ◽  
Krishna Mukkanna ◽  
Girish Patel ◽  
Stefan Docjinov ◽  
...  
Keyword(s):  
Surgical Excision ◽  
Skin Lesions ◽  
Hair Follicles ◽  
The Body ◽  
Low Grade ◽  
Outer Root Sheath ◽  
Rare Tumour ◽  
Suspected Infection ◽  
Root Sheath ◽  
History Of

Trichilemmal carcinoma is a rare tumour derived from the outer root sheath of hair follicles.  It can be difficult to distinguish both clinically and histologically from other skin lesions, particularly squamous cell carcinoma.  We present the case of a 62-year-old female with a 20-year history of three 1-cm cysts on her scalp.  Over a six-month period, a cyst overlying the occiput had become painful and grown in size.  The general practitioner and subsequently local emergency department suspected infection.  The lesion was incised, and the patient was treated with oral antibiotics.  At the time of surgical excision, the lesion measured 3 x 4 cm. Microscopic examination identified rounded dermal lobules of squamous epithelium with trichilemmal keratinization, in keeping with a pre-existing pilar cyst.  There were areas with nuclear pleomorphism, mitoses and an infiltrative architecture.  A diagnosis of trichilemmal carcinoma arising in a pilar cyst was made.  Trichilemmal carcinomas are considered to be a low-grade tumour, but they have the potential to spread to lymph nodes and to metastasise to distant sites in the body, therefore adequate excision and appropriate follow-up are required.

Frontal Base Gliosarcoma Mimicking as Olfactory Groove Meningioma- A Rare Case Report

2019 ◽  
Vol 8 (2) ◽  
pp. 108-111
Author(s):  
Kaisar Haroon ◽  
Tania Taher ◽  
Abdullah Alamgir ◽  
Naila Huq ◽  
Md Arif Reza ◽  
...  
Keyword(s):  
Case Report ◽  
The Body ◽  
Intracranial Tumour ◽  
Rare Tumour ◽  
Olfactory Groove ◽  
Rare Case Report ◽  
History Of ◽  
Olfactory Groove Meningioma ◽  
The Brain ◽  
Variable Presentation

Gliosarcoma is a rare tumour of the brain. It is a type of the gliobalstoma. This tumour has high complication rate as well as mortality. In our Institution, a 30 year old female was admitted with the complaints of headache and vomiting and weakness of rt. side of the body. She had history of radiotherapy on the frontal bone at four years age and following enucleation of the left eye. Now her recent MRI showed features of a tumor compatible with olfactory groove meningioma. She underwent craniotomy and her tumour was removed. Her histopathological exam was compatible with gliosarcoma which was confirmed with immunohistochemistry. And she was referred to oncologist for further management. Gliosarcoma is a rare intracranial tumour which has variable presentation. The aim of this case report is to present a secondary gliosarcoma which had presented as olfactory groove meningioma. Bang. J Neurosurgery 2019; 8(2): 108-111

scholarly journals Atopic Dermatitis and Psoriasis as Overlapping Syndromes

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
A. Bozek ◽  
M. Zajac ◽  
M. Krupka
Keyword(s):  
Atopic Dermatitis ◽  
Family History ◽  
Atopic Disease ◽  
Skin Lesions ◽  
The Body ◽  
T Helper 17 ◽  
Tnf Α ◽  
History Of

Background/Objectives. Cooccurrence of atopic dermatitis (AD) and psoriasis (PS) is not common. However, both diseases are still of interest because of their comprehensive and diverse mechanisms. This study aimed to present the clinical and immunological profiles of patients with concomitant AD and PS and compare them with those of patients with only one of the diseases. Methods. In this observational study, 38 children with concomitant AD and PS with a mean age of 6.5 ± 3.2  yrs were compared with 41 similar patients with AD only ( 5.3 ± 5.1  yrs) and 28 patients with PS only ( 6.4 ± 4.3  yrs). All patients underwent dermatological examinations, including determination of SCORAD and PASI scores. TNF-α, IFN-γ, IL-2, IL-4, IL-5, IL-6, IL-8, IL-12, IL-17, IL-18, IL-22, I:-33, and TARC/CCL17 were measured by ELISA according to the manufacturer’s instructions. Results. Patients with concomitant AD and PS were frequently boys and overweight and had skin lesions equally distributed throughout the body. Children with concomitant AD and PS were more likely to report a family history of atopic disease than children with only AD or PS, and those with AD were more likely to report a family history of atopic disease than those with PS. Significant differences were observed in the concentration of IL-17 between patients with AD and PS and those with only AD or PS: 9.1 ± 3.7  pg/ml vs. 4.8 ± 2.9  pg/ml; and 9.1 ± 3.7  pg/ml vs. 5.2 ± 3.9  pg/ml, respectively (PD vs. AD, p = 0.01 ; PD vs. PS, p = 0.03 ). Conclusions. AD and PS can coexist. The role of T helper 17 cells may be more essential than believed.

Disseminated Cutaneous Rhinosporidiosis: A Rare Case Report

2016 ◽  
Vol 8 (2) ◽  
pp. 72-74
Author(s):  
Ankita Joshi ◽  
Chinmaya S Ray ◽  
Rabindra K Khatua
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Maxillary Antrum ◽  
The Body ◽  
Rural South ◽  
Nasal Mass ◽  
Medical College ◽  
Rare Case Report ◽  
History Of ◽  
Granulomatous Disorder

ABSTRACT Rhinosporidiosis is a chronic granulomatous disorder caused by Rhinosporidium seeberi. It usually presents as a soft polypoidal pedunculated or sessile mass. Nose and nasopharynx are the commonly affected sites, but other sites, such as conjunctiva, the lips, palate, uvula, maxillary antrum, epiglottis, larynx, trachea, bronchus, ear, scalp, vulva, vagina, penis, and rectum, have been reported. However, cutaneous manifestation is rare. We report such a case of a 50-year-old male patient from rural south Odisha presenting to the ENT Department of SCB Medical College and Hospital, Cuttack, with multiple granulomatous growths of different sizes all over the body, along with a nasal mass, of 2½-year duration. He also gives history of a surgery on his nose 3 year back. Histopathology of the excised cutaneous and nasal lesions confirmed our diagnosis as rhinosporidiosis. On the basis of these clinical and histopathological findings, a diagnosis of nasal rhinosporidiosis with disseminated cutaneous spread was made. How to cite this article Ray CS, Joshi A, Khatua RK. Disseminated Cutaneous Rhinosporidiosis: A Rare Case Report. Int J Otorhinolaryngol Clin 2016;8(2):72-74.

scholarly journals Mixed Cutaneous Infection Caused by Leishmania and Dermatophytes: A Rare Coincidence or Immunological Fact

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Amresh Kumar Singh ◽  
Ankur Kumar ◽  
Jayesh Pandey ◽  
Vivek Gaur ◽  
Pratima Tripathi ◽  
...  
Keyword(s):  
Cellular Immunity ◽  
Uttar Pradesh ◽  
Skin Lesions ◽  
The Body ◽  
Cell Mediated Immunity ◽  
Kala Azar ◽  
Healthy Female ◽  
History Of ◽  
Loss Of Appetite

Leishmaniasis was first described in 1824, in the Jessore district of Bengal (now Bangladesh) and more prevalent in Bihar, Uttar Pradesh, Jharkhand, and West Bengal. The disease is associated with depressed cellular immunity. Tinea is a fungal infection of the skin, which can become more extensively pathogenic particularly in patients with depressed cell-mediated immunity. Regulatory T cells and Th17 cells have been shown to be responsible for post-kala-azar dermal leishmaniasis (PKDL). We present a rare case of a 52-year-old house wife with a history of recurrent itching, depigmentation of the skin of extremities, and loss of appetite for 2-3 months followed by progressive spread of such lesion all over the body in an apparently healthy female. On examination, there were many hypopigmented scaly lesions mainly over the extensor aspect of the body. Skin lesions were characteristics of tinea infection with or without PKDL. A diagnosis of PKDL with tinea was made based on the history of kala-azar and on the skin slit smear for amastigote forms, rK39 test, and KOH mount. Routine blood investigations showed negative serology for HIV and lower normal CD4+T counts. The patient was advised for treatment on systemic antifungal therapy with antihistaminics and later with miltefosine. We have highlighted that PKDL, although uncommon, is a distinct manifestation of VL. In our case study, we also tried to find the reason of coinfection; this was probably due to the depressed cellular immunity, skin abruptions, and acquired dermatophytic infection which is prevalent and associated with lower CD4+ T cell count.

Atypical Femoral Fracture in McCune-Albright Syndrome

2020 ◽  
Vol 7 (3) ◽  
pp. 147-152
Author(s):  
Salman Ghaffari ◽  
◽  
Mehran Razavipour ◽  
Parastoo Mohammad Amini ◽  
◽  
...  
Keyword(s):  
Femoral Fracture ◽  
Dynamic Compression ◽  
Plate Fixation ◽  
Medullary Canal ◽  
Mccune Albright Syndrome ◽  
Café Au Lait Spots ◽  
History Of ◽  
Albright Syndrome ◽  
Mccune Albright

McCune-Albright Syndrome (MAS) is characterized by endocrinopathies, café-au-lait spots, and fibrous dysplasia. Bisphosphonates are the most prescribed treatment for reducing the pain but their long-term use has been associated with atypical fractures of cortical bones like femur in patients. We present a 23-year-old girl diagnosed with MAS. She had an atypical mid-shaft left femoral fracture that happened during simple walking. She also had a history of long-term use of alendronate. Because of the narrow medullary canal, we used 14 holes hybrid locking plate for the lateral aspect of the thigh to fix the fracture and 5 holes dynamic compression plate (instead of the intramedullary nail) in the anterior surface to double fix it, reducing the probability of device failure. With double plate fixation and discontinuation of alendronate, the complete union was achieved five months after surgery

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