scholarly journals EXPERIENCE IN THE TREATMENT OF CHILDREN WITH VASCULAR TUMORS OF THE MAXILLOFACIAL AREA

2018 ◽  
Vol 14 (4) ◽  
pp. 82-86 ◽  
Author(s):  
Ирина Замятина ◽  
Irina Zamyatina ◽  
Евгения Бимбас ◽  
Evgeniya Bimbas ◽  
Валентина Вольхина ◽  
...  
Keyword(s):  
Blood Flow ◽  
Young Children ◽  
High Efficiency ◽  
Treatment Time ◽  
Combined Treatment ◽  
Treatment Method ◽  
Linear Velocity ◽  
Combination Method ◽  
Vascular Tumors ◽  
Comparison Groups

Subject. The article shows the effectiveness of the author's method of treatment of young children with vascular tumors of the maxillofacial area. The variety of the clinical course of vascular tumors, their localization in the maxillofacial area create difficulties and limit the choice of treatment method. The author's method combines high efficiency, minimally invasiveness, reduction of rehabilitation time and minimal adverse reactions. Objective ― evaluation of the experience of treating vascular tumors of the maxillofacial region in children using a combination method - taking propranolol and hardening. Methodology. The results of the treatment of 120 children with vascular tumors of the maxillofacial area aged 2 months to 2 years have been evaluated. Compared the results in 3 groups of children who were treated by various methods: combined - taking propranolol and hardening (FG); propranolol (HS-1); sclerotherapy method (HS-2). The efficacy of treatment was assessed by changing the volume of formation, the diameter of the supply vessels and the values of the linear velocity of blood flow. Results. According to the results of our clinical study, a group of young children with vascular tumors of the maxillofacial area in cosmetically significant areas that received treatment by the author's method, has demonstrated its effectiveness. A significant amount of regression was achieved (2.5 times) compared with the comparison groups. According to the ultrasound, the reduction in the diameter of the supply vessels and the linear velocity of blood flow reached zero after 6 months after the start of treatment, faster than in the comparison groups Conclusions. The use of the combined treatment - taking propranolol and hardening - is effective in treating children with vascular tumors of the maxillofacial area, reduces the treatment time and reduces the risk and degree of complications.

scholarly journals Efficient, high-resolution topology optimization method based on convolutional neural networks

2021 ◽  
Author(s):  
Liang Xue ◽  
Jie Liu ◽  
Guilin Wen ◽  
Hongxin Wang
Keyword(s):  
Topology Optimization ◽  
High Resolution ◽  
High Efficiency ◽  
Optimization Problems ◽  
Combined Treatment ◽  
Computational Cost ◽  
Treatment Method ◽  
Optimization Method ◽  
Arbitrary Boundary ◽  
Topology Optimization Method

AbstractTopology optimization is a pioneer design method that can provide various candidates with high mechanical properties. However, high resolution is desired for optimum structures, but it normally leads to a computationally intractable puzzle, especially for the solid isotropic material with penalization (SIMP) method. In this study, an efficient, high-resolution topology optimization method is developed based on the superresolution convolutional neural network (SRCNN) technique in the framework of SIMP. SRCNN involves four processes, namely, refinement, path extraction and representation, nonlinear mapping, and image reconstruction. High computational efficiency is achieved with a pooling strategy that can balance the number of finite element analyses and the output mesh in the optimization process. A combined treatment method that uses 2D SRCNN is built as another speed-up strategy to reduce the high computational cost and memory requirements for 3D topology optimization problems. Typical examples show that the high-resolution topology optimization method using SRCNN demonstrates excellent applicability and high efficiency when used for 2D and 3D problems with arbitrary boundary conditions, any design domain shape, and varied load.

scholarly journals Evaluation of Treatment Outcomes in Children with Maxillofacial Vascular Tumors: Cohort Study

2019 ◽  
Vol 6 (1) ◽  
pp. 16-24
Author(s):  
Irina A. Zamyatina ◽  
Evgenia S. Bimbas ◽  
Olga A. Lvova
Keyword(s):  
Blood Flow ◽  
Cohort Study ◽  
Comparison Group ◽  
Combined Treatment ◽  
Group Analysis ◽  
Main Group ◽  
Vascular Tumors ◽  
Duration Of Treatment ◽  
Results Of Treatment ◽  
Group Reduction

Background. The variety of the clinical features of vascular tumors in the maxillofacial area limits the choice of method and is able to make difficulties in the treatment. The combined method of treatment proposed by the authors (vascular sclerotherapy with concurrent propranolol intake) demonstrates high efficacy, lack of invasiveness, shortening the rehabilitation period and less side effects. Objective. The aim of the study was to increase the effectiveness of conservative treatment of vascular tumors of the maxillofacial area in young children by combining the method of sclerotherapy and taking propronolol. Methods. In a cohort study, the results of treatment of 80 children aged 2 months to 2 years with vascular tumors of the maxillofacial region (ICD-10: D18.0) were evaluated. A comparison was made of the results in 2 groups of children who were treated with different methods: combined (n =40; main group; sclerotherapy and taking propranolol) and propranolol monotherapy (n =40; comparison group). Analysis of the data obtained in the main group and the comparison group led to the development of the criteria for evaluating the treatment results: good (regression of vascular tumors and the absence of a cosmetic defect), satisfactory (reduction of vascular tumors by 2/3 or more with maintaining cosmetic defect) and unsatisfactory (gross cosmetic defect) in terms of changes in the volume of tumor, the diameter of the supply vessels and the values of the linear velocity of blood flow according to ultrasound data. Results. Subjects treated by the combined treatment had a significant regression of vascular tumors in the maxillofacial area compared with the comparison group: reduction of the tumor volume, diameter of the supply vessels and linear blood flow velocity according ultrasound data reached zero after 6 months from the start of combined treatment — 6 months earlier than in the comparison group (p <0.001). Conclusion. According to the results of the study, the advantage of the author’s method over the traditional method was demonstrated, which resulted in a reduction in the duration of treatment, a decrease in the risk as well as in a degree of complications.

scholarly journals AB1264 THE EFFECTIVENESS OF KINESIOTHERAPY FOR PAIN SHOULDER SYNDROME

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1923.2-1924
Author(s):  
O. Tikhoplav ◽  
E. Guryanova ◽  
O. Moskovskaya ◽  
A. Moskovskij
Keyword(s):  
High Efficiency ◽  
Clinical Symptoms ◽  
Physical Therapist ◽  
Combined Treatment ◽  
Total Duration ◽  
Pain Syndrome ◽  
Treatment Method ◽  
Rehabilitation Medicine ◽  
Vas Score ◽  
Shoulder Syndrome

Background:Pain shoulder syndrome is one of the most common conditions that is inherent in patients with various diseases and conditions. This problem is faced by both patients of a rheumatological profile (rheumatoid arthritis), and patients of other profiles: neurological (stroke, hernia of the cervical spine), traumatological (periarthritis). The regular use of painkillers and NSAID is associated with a risk of serious adverse reactions in patients.PNF therapy can have a fairly quick positive effect. Kinesiotaiping is a common and easily accessible treatment method that, due to the inclusion of local neuromuscular adaptation mechanisms, can have an analgesic effect.Objectives:The purpose of the study is to compare the effectiveness of traditional treatment methods in combination.Methods:Patients with pain shoulder syndrome who were admitted to the doctor of physical and rehabilitation medicine were randomly assigned to one of three groups: group G1 - 20 patients who received combined treatment, including massage, acupuncture, PNF, kinesiotherapy.Patients of group G2 (20 people) who received massage and acupuncture sessions, kinesiotherapy, but did not deal with PNF.Patients in group G3 (20 people) received massage, acupuncture, and PNF, excluding kinesiotaping.All patients received treatment 5 times a week (Monday to Friday, excluding Saturday and Sunday), the total duration of the rehabilitation course is 20 days. The program included: 30 minutes an acupuncture session, 20 minutes massage, 45 minutes physical exercises with a physical therapist. Classes using the PNF technique were carried out separately every other day for 45 minutes using the standard method for shoulder pain.VAS was used to monitor efficacy. Pain was assessed at the beginning of the study, with the third, sixth, ninth and last visit to the clinic.Results:The age composition of the patient group is from 31 to 70 years. The gender composition is 35 (58.33%) women, and 25 (41.67%) men.The average time between the onset of clinical symptoms and the first treatment session was 47.3 days. In 90% of patients, a history of pain lasted from 6 weeks or more. 52 patients (86.67%) completed the treatment completely. Of these, G1 is 19 people (90% of this group), 16 (80%) in G2, and 17 of 20 in the G3 group (85%).The average VAS score in G1 was 5.15 at the start of the study, and after the tenth session, it dropped to 2.78. A significant decrease in pain is also observed in the G2 group (from 5.17 at the beginning of the study to 3.19 after the tenth session). The G3 group in terms of pain reduction almost equaled the G1 group, where the level of pain from 5.16 decreased to 2.71.Patients within 6 months after treatment evaluated the level of pain on their own and reported the data to the doctor. In patients of group G1, after 6 months, the average VAS score is 3.71. G3 patients after 6 months, the VAS score is 4.25 points. Patients of the G2 group at 3 months noted a return of the pain syndrome, after 3 months, the VAS score was 5.11.Conclusion:The obtained results testify to the high efficiency of PNF therapy, however, the combination with kinesiotyping allows better consolidation of the effect of therapy and prolongs remission of pain syndrome.Disclosure of Interests:None declared

scholarly journals Safe and Effective Treatment of Intracranial Infantile Hemangiomas with Beta-Blockers

2021 ◽  
Vol 13 (3) ◽  
pp. 347-356
Author(s):  
Aoife Naughton ◽  
Ariel Yuhan Ong ◽  
Goran Darius Hildebrand
Keyword(s):  
Effective Treatment ◽  
Beta Blockers ◽  
Combined Treatment ◽  
Infantile Hemangioma ◽  
Intracranial Extension ◽  
Vascular Tumors ◽  
Complete Regression ◽  
Pharmacological Management ◽  
Excellent Outcome ◽  
The Right

Infantile hemangiomas are common benign vascular tumors but are rarely found in an intracranial location. Our literature review identified 41 reported cases. There is no general consensus on management of these rare lesions and until recently, treatment was limited to surgery or pharmacological management with steroids or interferon. Although beta-blockers have been widely prescribed in the treatment of cutaneous infantile hemangiomas since 2008, their use in the treatment of intracranial infantile hemangiomas has been minimal. We present a case of infantile hemangioma affecting the right orbit, associated with intracranial extension, causing intermittent right facial nerve palsy. The patient achieved an excellent outcome following combined treatment with oral propranolol and topical timolol maleate 0.5%, with complete regression of the lesion by 4 months. We conclude that beta-blockers are a safe and effective treatment of intracranial infantile hemangiomas and can be employed as first-line management of these lesions.

scholarly journals Predictors of cervical myelopathy and hydrocephalus in young children with achondroplasia

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Youngbo Shim ◽  
Jung Min Ko ◽  
Tae-Joon Cho ◽  
Seung‐Ki Kim ◽  
Ji Hoon Phi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Young Children ◽  
Cervical Myelopathy ◽  
Treatment Method ◽  
Foramen Magnum ◽  
Resonance Imaging ◽  
Timely Manner ◽  
Frontal Horn ◽  
National University ◽  
Seoul National University

Abstract Background Cervical myelopathy and hydrocephalus occasionally occur in young children with achondroplasia. However, these conditions are not evaluated in a timely manner in many cases. The current study presents significant predictors for cervical myelopathy and hydrocephalus in young children with achondroplasia. Methods A retrospective analysis of 65 patients with achondroplasia who visited Seoul National University Children’s Hospital since 2012 was performed. The patients were divided into groups according to the presence of cervical myelopathy and hydrocephalus, and differences in foramen magnum parameters and ventricular parameters by magnetic resonance imaging between groups were analyzed. Predictors for cervical myelopathy and hydrocephalus were analyzed, and the cut-off points for significant ones were calculated. Results The group with cervical myelopathy showed foramen magnum parameters that indicated significantly lower cord thickness than in the group without cervical myelopathy, and the group with hydrocephalus showed significantly higher ventricular parameters and ‘Posterior indentation’ grade than the group without hydrocephalus. ‘Cord constriction ratio’ (OR 5199.90, p = 0.001) for cervical myelopathy and ‘Frontal horn width’ (OR 1.14, p = 0.001) and ‘Posterior indentation’ grade (grade 1: OR 9.25, p = 0.06; grade 2: OR 18.50, p = 0.01) for hydrocephalus were significant predictors. The cut-off points for cervical myelopathy were ‘Cord constriction ratio’ of 0.25 and ‘FM AP’ of 8 mm (AUC 0.821 and 0.862, respectively) and ‘Frontal horn width’ of 50 mm and ‘Posterior indentation’ grade of 0 (AUC 0.788 and 0.758, respectively) for hydrocephalus. Conclusion ‘Cord constriction ratio’ for cervical myelopathy and ‘Frontal horn width’ and ‘Posterior indentation’ grade for hydrocephalus were significant predictors and may be used as useful parameters for management. ‘Posterior indentation’ grade may also be used to determine the treatment method for hydrocephalus.

An Analytical Evaluation of the Optimal Thermal Dose Delivery Parameters for Thermal Therapies

2003 ◽  
Author(s):  
Kung-Shan Cheng ◽  
Robert B. Roemer
Keyword(s):  
Blood Flow ◽  
Treatment Time ◽  
Heating Time ◽  
Treatment Temperature ◽  
Thermal Dose ◽  
Dose Delivery ◽  
Thermal Therapies ◽  
Initial Power ◽  
High Treatment ◽  
Optimal Heating

This study derives the first analytic solution for evaluating the optimal treatment parameters needed for delivering a desired thermal dose during thermal therapies consisting of a single heating pulse. Each treatment is divided into four time periods (two power-on and two power-off), and the thermal dose delivered during each of those periods is evaluated using the non-linear Sapareto and Dewey equation relating thermal dose to temperature and time. The results reveal that the thermal dose delivered during the second power-on period when T&gt;43C (TD2) and the initial power-off period when T&gt;43C (TD3) contribute the major portions of the total thermal dose needed for a successful treatment (taken as 240 CEM43°C), and that TD3 dominates for treatments with higher peak temperatures. For a fixed perfusion value, the analytical results show that once the maximum treatment temperature and the total thermal dose (e.g., 240 CEM43°C) are specified, then the required heating time and the applied power magnitude are uniquely determined. These are the optimal heating parameters since lower/higher values result in under-dosing/over-dosing of the treated region. It is also shown that higher maximum treatment temperatures result in shorter treatment times, and for each patient blood flow there is a maximum allowable temperature that can be used to reach the desired thermal dose. In addition, since TD2 and TD3 contribute most of the total thermal dose, and they are both significantly affected by the blood flow present for high treatment temperatures, these results show that perfusion effects must be considered when attempting to optimize high temperature thermal therapy treatments (no excess thermal dose delivered, minimum power applied and shortest treatment time attained).

scholarly journals Gold Extraction from Cyanidation Tailing Using Microwave Chlorination Roasting Method

Metals ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 1025 ◽  
Author(s):  
Fei Zhu ◽  
Libo Zhang ◽  
Haoyu Li ◽  
Shaohua Yin ◽  
Sivasankar Koppala ◽  
...  
Keyword(s):  
Microwave Field ◽  
High Efficiency ◽  
Chloride Concentration ◽  
Treatment Method ◽  
Gold Extraction ◽  
Microwave Roasting ◽  
Gold Mines ◽  
Chlorination Roasting ◽  
New Treatment ◽  
Gold Industry

At present, gold mines are increasingly scarce in the world. The yield of cyanidation tailing (CT) of refractory gold ores with a grade of 10 g/T is huge; however, the effective capitalization of the cyanidation tailing is a significant problem in the gold industry. In this work, a new treatment method, a microwave-roasting process developed. The effect of roasting temperature, calcium chloride concentration, holding time and mineral size on the recovery of Au researched under conventional and microwave conditions. It found that, under the same processing conditions, the Au recovery in the microwave field is much higher than that of conventional conditions. The preliminary reinforcing role of the microwave discussed in the recovery of gold. This might be because of the microwave absorption ability of CaCl2 is much better, heated quickly and the reactions intensified among CaCl2, O2, and H2O. As a result, the extraction of gold in CT drastically increased in the microwave field, and the microwave roasting technology shows the characteristics of environmental protection in terms of low energy consumption and high efficiency.

Ablative therapies for liver metastases of digestive endocrine tumours.

2003 ◽  
pp. 463-468 ◽  
Author(s):  
D O'Toole ◽  
F Maire ◽  
P Ruszniewski
Keyword(s):  
Liver Metastases ◽  
Somatostatin Analogs ◽  
Hepatic Metastases ◽  
Vascular Occlusion ◽  
Treatment Method ◽  
Vascular Tumors ◽  
Endocrine Tumors ◽  
Hepatic Ischemia ◽  
Ablative Therapies

Hepatic metastases are frequently encountered in patients with digestive endocrine tumors and their presence plays an important role in quality of life and overall prognosis. Surgery is the treatment method of choice for hepatic metastases but this is frequently impossible due to the extent of disease. Systemic chemotherapy is offered to patients with diffuse and/or progressive liver metastases but results are disappointing especially in patients with metastases of midgut origin. In the latter patients with carcinoid syndrome, somatostatin analogs are frequently initially effective but their efficacy wanes due to disease progression and development of tachyphylaxis. Other therapeutic options in the treatment of hepatic metastases are locoregional strategies where vascular occlusion induces ischemia in these highly vascular tumors using either surgical or radiological techniques. Available methods include surgical ligation of the hepatic artery, transient hepatic ischemia or sequential hepatic arterialization. Trans-catheter arterial chemoembolization has proven effective in terms of long palliation and objective tumor responses. Other treatments aimed at regional destruction either alone or in combination with surgery include radiofrequency ablation and cryotherapy. The latter are usually important adjuncts to surgery and are usually reserved for limited disease.

scholarly journals Therapeutic approach to children’s intussusception at late hospitalization

2003 ◽  
Vol 2 (2) ◽  
pp. 72-77
Author(s):  
M. K. Belyaev ◽  
K. K. Fyodorov
Keyword(s):  
Old Age ◽  
Therapeutic Approach ◽  
Pediatric Surgery ◽  
High Efficiency ◽  
Abdominal Cavity ◽  
Treatment Method ◽  
Time Period

The goal of the investigation was to define whether conservative disinvagination would be safe and effective for long children’s intussusception. 368 children of 1 month to 13 years old age with intussusception have been treated in Novokuznetsk’ pediatric surgery clinic for a period from 1976 up to 2001. The number of boys was 248 (67,4%) and girls — 120 (32,6%) respectively. Patients of the age up to 1 year old were 185 (50,3%), older than 1 year — 183 (49,7%). 214 patients (58,2%) were hospitalized during the first 12 hours from the disease began, 71 patients (19,3%) — during 12—24 hours, 48 patients (13%) — during 24—48 hours, 35 patients (9,5%) — after 48 hours. In our clinic the method of conservative intussusception therapy is considered to be the priority and its application, if there are no any abdominal cavity complications (peritonitis), does not depend on introducing form, patients’ age, time period of hospitalization following the disease or recurrence beginning. The bloodless therapy has been found to be effective: the 1th stage — 93,2%, the 2nd stage — 93%, the 3d stage — 86,4% and the 4th stage — 91,7%. Thus, our facts earnestly prove both the potential of bloodless intussusception treatment method for children at late hospitalization (after 24 hours) and its safety and high efficiency (88,3%).

scholarly journals Stepwise separation of poplar wood in oxalic acid/water and γ-valerolactone/water systems

RSC Advances ◽  
2020 ◽  
Vol 10 (19) ◽  
pp. 11188-11199
Author(s):  
Liuming Song ◽  
Ruizhen Wang ◽  
Jianchun Jiang ◽  
Junming Xu ◽  
Jinsheng Gou
Keyword(s):  
Oxalic Acid ◽  
Combined Treatment ◽  
Treatment Method ◽  
Water Systems ◽  
Acid Water ◽  
Poplar Wood

A combined treatment method of oxalic acid/H2O and γ-valerolactone/H2O can be used for efficient fractionation of hemicellulose, cellulose, and lignin.

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