high treatment
Recently Published Documents


TOTAL DOCUMENTS

205
(FIVE YEARS 89)

H-INDEX

20
(FIVE YEARS 4)

Cells ◽  
2022 ◽  
Vol 11 (2) ◽  
pp. 284
Author(s):  
Paulina Wigner ◽  
Michał Bijak ◽  
Joanna Saluk-Bijak

Nephrolithiasis ranks third among urological diseases in terms of prevalence, making up about 15% of cases. The continued increase in the incidence of nephrolithiasis is most probably due to changes in eating habits (high protein, sodium, and sugar diets) and lifestyle (reduced physical activity) in all developed countries. Some 80% of all kidney stones cases are oxalate urolithiasis, which is also characterized by the highest risk of recurrence. Frequent relapses of nephrolithiasis contribute to severe complications and high treatment costs. Unfortunately, there is no known effective way to prevent urolithiasis at present. In cases of diet-related urolithiasis, dietary changes may prevent recurrence. However, in some patients, the condition is unrelated to diet; in such cases, there is evidence to support the use of stone-related medications. Interestingly, a growing body of evidence indicates the potential of the microbiome to reduce the risk of developing renal colic. Previous studies have primarily focused on the use of Oxalobacterformigenes in patients with urolithiasis. Unfortunately, this bacterium is not an ideal probiotic due to its antibiotic sensitivity and low pH. Therefore, subsequent studies sought to find bacteria which are capable of oxalate degradation, focusing on well-known probiotics including Lactobacillus and Bifidobacterium strains, Eubacterium lentum, Enterococcus faecalis, and Escherichia coli.


2022 ◽  
Vol 9 (1) ◽  
pp. 45-50
Author(s):  
Jonathan Setiawan ◽  
Ida Ayu Alit Widhiartini ◽  
I Gusti Made Aman

Treatment motivation among patients were heavily influenced by duration of therapy and existing side effects. TB supervisors motivated patients in their therapy. Limited communication from TB supervisors due to COVID-19 pandemic risked lowering treatment motivation in TB patients. Objective: get a general description of treatment motivation in TB patients from PHC in Denpasar. Method: descriptive observational with cross-sectional design in March – August 2021 at five PHC in Denpasar area. This study was done online using questionnaire with Google Forms application. Motivation is grouped into low, moderate, and high based on scores from internal factors, external factors, confidence in treatment, and interpersonal help seeking. Results: 86% of patients (43 people) had high treatment motivation, 12% of patients (6 people) have moderate treatment motivation, and two percent of patients (1 people) had low treatment motivation. Summary: Most of TB patients had high treatment motivation (86%). Communication between TB supervisors and patients are highly advised to motivate patients and increase success rate of therapy. Keywords: [Anti tuberculosis drugs, Lung tuberculosis, Treatment motivation].


2021 ◽  
Vol 9 (3) ◽  
pp. 1104-1112
Author(s):  
Tahmina Akter ◽  
Mansura Mokbul ◽  
Susmita Ghosh ◽  
Moumita Dey

Milk is an ideal food for all age groups. The current study was carried out to identify the microorganisms to assess the raw milk quality and the antibiotic resistance of those identified micro-organisms. Five raw milk samples along with two high treatment (UHT) milk samples from different locations of Noakhali district of Bangladesh were analysed. Bacterial isolation was performed by Nutrient Agar (NA) and MacConkey (MCA), Eiosin Methylene Blue (EMB) and Genital menital salt agar (GMSA). The isolates were then identified by Kliger’s Iron Agar (KIA) test, Motility Indole Urease (MIU) test, Catalase and Oxidase tests. Antibiotics resistance tests were done for 13 different antibiotics. Among all these samples, Maijdee Bazar (S4) contained the highest load as 1.87×106 and the UHT samples contained no bacterial contamination. E. coli covered 47.05% whereas Listeria, Bacillus and Yersinia were in the same percentage as 5.88% among all isolates. Salmonella and Staphylococcus were 23.53% and 11.76%, respectively. Listeria and Salmonella were resistant to five different antibiotics by 46.15% and 38.46% of multiple antibiotic resistance index (MRI), correspondingly. However, E. coli and Yersinia were resistant to three antibiotics namely, Rifampcin (RIF), Cefotaxime (CTX), Amoxycillin (AMX) by about 23% as MRI percentage. Bacillus and Staphylococcus both were resistant to Cefepime (CPM) by 7.69% of MRI. Hence, it can be concluded that Rifampcin and Cefepime were most common antibiotics which were resisted by most of the isolates. Therefore, hygiene aspect of these milk sources needs to be taken into consideration with high priority. Also, the antibiotics which are resisted by different organisms will be detrimental for public health aspects.


Crystals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1486
Author(s):  
Yi-Chen Chen ◽  
Wei-Hao Lee ◽  
Yung-Chin Ding

Aggregate sludge is a waste product produced from crushing, screening, and washing processes at aggregate plants. Because of the large quantity and high treatment cost of this sludge, it cannot be disposed of as landfill, and thus, has caused environmental concern over the years in Taiwan. In this preliminary study, the recycled aggregate sludge was reutilized for construction applications through the geopolymerization process. The ground granulated blast furnace slag (GGBFS) and fly ash (FA) were selected as alkaline activated materials for the fabrication of sludge geopolymer. Several process parameters that may affect the mechanical and physical properties of geopolymer were investigated. These parameters are sludge/GGBFS/FA ratios, solid/liquid (alkali solution) ratio, the molarity of NaOH, and curing time. According to the test results, the compressive strength of geopolymer specimens (70/30 sludge/GGBFS ratios) made with 4 M and 6 M NaOH can reach 39.17 MPa and 43.6 MPa after 28 days of curing. The specimen made with 60/40 sludge/GGBFS ratios has a strength of 61.3 MPa. After replacing GGBFS with 10% fly ash (70/20/10 sludge/GGBFS/FA), the strength of the specimen can also reach 43 MPa. According to the test results obtained in this study, it was found that the higher the NaOH concentration, the higher the strength of the geopolymer, and the GGBFS also can contribute more to the mechanical properties of geopolymer than fly ash. This preliminary study suggests that it is possible to reutilize aggregate sludge for construction applications and solve its environmental disposal problem.


2021 ◽  
Vol 55 (8) ◽  
Author(s):  
Tania Saskianti ◽  
Angela Faustina Kartono ◽  
Ayudia Rifki ◽  
Yufita Fitriani ◽  
Pradita Agung Kurnia

A common benign lesion in children’s oral cavity is mucocele on the lower lips that originates from the accumulation of mucous due to local trauma and a lip-biting habit. Lip-biting is often motivated by a psychological condition of anxiety. Mucoceles are painless but can be bothersome for patients when eating and speaking. Mucoceles can affect the general population but are more common among the young. The etiology of oral mucoceles may vary, and surgical treatment is best chosen for its convenience, child-friendliness, and high treatment success rate. Awareness education for children and parents is necessary to eliminate a lip-biting habit. If the pattern persists due to anxiety, it is essential to inquire more about the etiology and consult a professional psychologist.


2021 ◽  
pp. 004947552110438
Author(s):  
Naman S. Shetty ◽  
Minnie Bodhanwala ◽  
Ira Shah

We aimed to determine the outcome of bacteriologically confirmed drug-resistant (DR) tuberculosis (TB) in 174 children. We found that DR-TB infected children have nonetheless a high treatment completion rate with a low incidence of fatality and treatment failure. Reversible adverse drug reactions are common during therapy.


PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0260003
Author(s):  
Phantitra Sudadech ◽  
Sittiruk Roytrakul ◽  
Orawee Kaewprasert ◽  
Auttawit Sirichoat ◽  
Ploenchan Chetchotisakd ◽  
...  

Mycobacterium abscessus (Mab) is one of the most drug resistant bacteria with a high treatment failure rate. Antimicrobial peptides (AMPs) are alternative therapeutic agents against this infection. This study was aimed to assess the in vitro activities of thirteen AMPs (S5, S52, S6, S61, S62, S63, KLK, KLK1, KLK2, Pug-1, Pug-2, Pug-3 and Pug-4) that have never been investigated against drug resistant Mab isolates. Only four novel modified AMPs (S61, S62, S63 and KLK1) provided the lowest minimum inhibitory concentration (MIC) values ranging from 200–400 μg/ml against the Mab ATCC19977 strain. These four potential AMPs were further tested with 16 clinical isolates of clarithromycin resistant Mab. The majority of the tested strains (10/16 isolates, 62.5%) showed ~99% kill by all four AMPs within 24 hours with an MIC <50 μg/ml. Only two isolates (12.5%) with acquired clarithromycin resistance, however, exhibited values <50 μg/ml of four potential AMPs, S61, S62, S63 and KLK1 after 3-days-incubation. At the MICs level, S63 showed the lowest toxicity with 1.50% hemolysis and 100% PBMC viability whereas KLK1 showed the highest hemolysis (10.21%) and lowest PBMC viability (93.52%). S61, S62 and S63 were further tested with clarithromycin-AMP interaction assays and found that 5/10 (50%) of selected isolates exhibited a synergistic interaction with 0.02–0.41 FICI values. This present study demonstrated the potential application of novel AMPs as an adjunctive treatment with clarithromycin against drug resistant Mab infection.


2021 ◽  
Vol 900 (1) ◽  
pp. 012015
Author(s):  
N Junakova ◽  
J Junak

Abstract The paper focuses on the evaluation of the use of vegetation for the removal of contaminants from wastewater through vegetation-based wastewater treatment plants. Subsequently, the specific efficiencies of wastewater treatment using a selected vegetation-based wastewater treatment plant are evaluated. The results show that vegetation-based wastewater treatment plants generally work at relatively high treatment efficiency, but one of the main factors influencing the treatment efficiency is the values of pollution indicators at the inflow to the wastewater treatment plant.


Author(s):  
Corey J. Ketchem ◽  
Kisan P. Thakkar ◽  
Angela Xue ◽  
Sumana Reddy ◽  
Lior Abramson ◽  
...  

2021 ◽  
Vol 27 (5) ◽  
pp. 1169-1176
Author(s):  
Se-Eun You

This study is for the treatment effect and wave efficiency shown by using camellia oil, a natural material, for hair damaged by heat perm, a chemical treatment. For this, An experimental group containing camellia oil and a control group without it were prepared. and then, hair tensile strength measurement, absorbance measurement, SEM(Scanning Electron Microscope) observation, and hair gloss measurement were tested. First, in the tensile strength measurement, the tensile strength of the heat perm with camellia oil was higher than that of the heat perm without camellia oil. And as a result of absorbance measurement using methylene blue, the average absorbance of hair containing camellia oil was low. Second, in SEM, heat perm containing camellia oil showed less cuticle damage. Also, there was no cuticle damage in the heat perm containing camellia oil compared to the heat perm without camellia oil in the time observation. As a result of the gloss measurement, the degree of damage according to the time of the heat perm increased, but the damage was less in the heat perm including camellia oil. Based on these results, it was found that camellia oil had a high treatment effect of heat perm.


Sign in / Sign up

Export Citation Format

Share Document